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Perianal Crohn's Disease - Washington Hospital Center

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<strong>Perianal</strong> Crohns <strong>Disease</strong><br />

Colorectal Colloquium<br />

<strong>Washington</strong>, DC<br />

November 2nd, 2012<br />

Allen Chudzinski, MD<br />

Colon and Rectal Surgery<br />

Georgetown University <strong>Hospital</strong>


<strong>Perianal</strong> Crohns<br />

• Often first sign of Crohns<br />

• Can precede intestinal symptoms by years<br />

• Pts with LB disease more likely to have<br />

perianal disease, compared to SB


• Fistula in ano<br />

<strong>Perianal</strong> <strong>Disease</strong><br />

• Rectovaginal Fistula<br />

• Fissure<br />

• Skin Tags<br />

• Hemorrhoids<br />

• Abscess<br />

• Anal Stenosis


• Multiple fistulas<br />

Signs<br />

• Lateral anal fissures<br />

• Large skin tags<br />

• Multiple lesions<br />

• Ulcerations<br />

• Anal stricture


<strong>Perianal</strong> Crohns


Workup<br />

• Colonoscopy, flexible sigmoidoscopy<br />

• ERUS<br />

• MRI<br />

• Exam under Anesthesia<br />

– Drain sepsis<br />

– Obtain biopsy


• Treatment options<br />

• Diversion?<br />

• Fistulotomy<br />

• Seton<br />

• I/D<br />

<strong>Perianal</strong> Crohn’s


Skin tags


Skin Tags<br />

• Most common finding in perianal Crohns<br />

• Edematous, thickened, large<br />

• Difficulty with cleansing<br />

• Can be painful


• Expectant<br />

• Sitz baths<br />

Skin Tag Treatment<br />

• Moist wipes for cleansing<br />

• Not advisable to resect<br />

• Exceptions in extreme circumstances


Abscess


<strong>Perianal</strong> Abscess


Abscess<br />

• 3 rd most common presentation<br />

• 70% associated with fistula-in-ano<br />

• Painful<br />

• Can become septic


Abscess Treatment


Abscess Treatment<br />

• Incision and Drainage<br />

• Office vs. OR<br />

• ID should be close to anal opening<br />

• Expectant fistula-in-ano<br />

• Fistula may already present


Abscess Fistula


Fistula in Ano<br />

• Second most common manifestation in<br />

perianal Crohns<br />

• Often one of the most challenging<br />

• Often complex fistulas


FISTULA


Fistula


Surgical Treatment<br />

• Depends on the severity<br />

• Active rectal disease?<br />

• Combined use of Biologics


Surgical Treatment<br />

• No active rectal disease?<br />

• Fistulotomy<br />

• Seton<br />

• Rectal Advancement flap


Complex Fistula


Surgical Treatment<br />

• Active Rectal <strong>Disease</strong> present<br />

• Seton/Fistulotomy<br />

• Biologic study on fistula closure<br />

• Diverting ostomy, +/- flap closure


Complex perianal Crohns


Anal Fissure


Fissure-nonCrohns<br />

• Split in anoderm in<br />

typically posterior<br />

midline<br />

• Often reported after<br />

hard bowel movement<br />

• scant amount bright<br />

red blood with pain


Anal Fissure Physiology<br />

• High resting pressure of the internal<br />

sphincter muscle<br />

• No differences in the maximum voluntary<br />

contraction ( external sphincter)


Anal Fissure<br />

• Reported to occur 20-35% of Crohns pts<br />

• Fairly common<br />

• Posterior(40%), Lateral(20%),<br />

Multiple(30%)<br />

• Pain mild compared to Non-Crohns


Anal Fissure<br />

• Nonoperative Treatment<br />

• Control proctitis ( Canasa)<br />

• Sometimes Ca+ Channel blockers and<br />

Lidocaine effective<br />

• If extreme pain EUA recommended<br />

• Extreme cases LIS


Lateral Internal Sphincterotomy


Rectovaginal Fistula


Rectovaginal fistula<br />

• In true <strong>Perianal</strong> Crohns disease can be<br />

devastating<br />

• Advancement Flap<br />

• Multilayer closure<br />

• Diversion<br />

• Gracilis muscle flap


RVF repair


RVF<br />

• Severe rectal disease present<br />

• Proctectomy


Hemorrhoids


Hemorrhoids<br />

Function<br />

Venous Plexus, sinusoids<br />

• Vascular structure whose walls do not<br />

contain muscle, thus sinusoids not veins<br />

• three main cushions: left lateral, right<br />

anteriorlateral, right posterolateral


Hemorrhoids<br />

Increased size in certain conditions<br />

Symptoms<br />

– Painless<br />

– Bleeding<br />

– Itching<br />

– Burning


Internal


External


Hemorrhoids<br />

• All attempts should be made at<br />

conservative therapy<br />

• Avoid surgery<br />

• Poor wound healing<br />

• Risk of fistula<br />

• Offered in extreme circumstances


External<br />

• Covered by anoderm: modified squamous<br />

epithelium w/o appendages<br />

• Innervated by somatic nerves – pain


External Hemorrhoids<br />

• Venous Congestion<br />

• SKIN<br />

• Thrombosed- Painful<br />

• Medical Treatment<br />

• Excision vs Thrombectomy<br />

• Significantly decrease in pain after 48-72h


Stenosis


• Spasmodic<br />

Anal Stenosis<br />

– Smooth Muscle Contraction<br />

• Fibrotic<br />

– Infectious, tissue destruction<br />

• Can be debilitating for patient


• Dilation<br />

• Bulk forming agents<br />

• Finger dilation<br />

• Operative dilation<br />

• Selected cases, LIS<br />

Anal Stenosis<br />

• Extreme-Proctectomy


Cancer<br />

• Always aware Crohns pts at increased risk<br />

• Colonoscopy<br />

• EUA<br />

• Biopsy

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