Medicinsk teknologivurdering af obstruktiv ... - Danske Regioner

Medicinsk teknologivurdering af obstruktiv ... - Danske Regioner

Medicinsk teknologivurdering af obstruktiv søvnapnø


This health technology assessment (HTA) concerns diagnostics, treatment and follow-up

of patients with obstructive sleep apnoea (OSA) and obesity hypoventilation syndrome

(OHS). The number of patients with OSA is growing and this report takes its starting point

in the treatment activities for this patient group. The report describes and assesses the

most recent level of evidence within diagnostics, treatment and follow-up in this patient

group. The report addresses primarily decision-makers and professionals in the field.


A Danish HTA on OSA from 2006 presents detailed descriptions of diagnostics and treatment

activities in both the public and private area. The HTA concludes that the patient

group is undertreated. For a number of years a growth in the treatment activity among patients

with OSA has been observed; Recently, it has been questioned if this growth in

treatment activity can be justified. Reported prevalence ratios indicate that the size of the

patient group is considerable. Previous studies have shown that treatment of OSA is associated

with increased quality of life and reduction in e.g. sleeplessness and blood pressure.

Complex diagnostic and treatment conditions, the development in diagnostic/treatment

methods as well as organisational and economical demands have made it necessary to

evaluate the consequences of diagnostics and treatment of patients with OSA.


The purpose of this HTA is to evaluate and describe the current knowledge and evidence

within the field of OSA including investigating prerequisites and consequences for different

approaches to diagnostics and treatment as well as organisational and economic conditions

related to treatment of patients with OSA. The HTA will contribute to the future

planning within the field. The report will also contribute to creating a common foundation

for diagnostics, treatment and follow-up for this patient group.


The report and the analysis of the perspectives are evaluated within the basic HTA framework

including technology, organisation and economy. Overall, the analyses are based on

national and international systematic reviews, recent primary studies not evaluated in

connection with the systematic review, and collection of primary data by questionnaires,

interviews and relevant databases. The purpose of the report is thus investigated using

different methods. A separate literature search and review has been made for each of the

main chapters of the report. The literature search is based on a protocol designed in advance

(appendix) and specific search strategies for each chapter. Search strategies and

protocol are stored as documentation.

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