Forskning 2008 - Herlev Hospital

herlevhospital.dk

Forskning 2008 - Herlev Hospital

Forskning 2008

Klinisk Mikrobiologisk Afdeling M

Forskningsområder

Infektionspatogenese.

Mikrobiologisk diagnostik ved hjælp af genamplifikationsteknik.

Epidemiologisk forskning.

Forskningsaktiviteter

Projekter vedrørende:

Stafylokokinfektioner.

Meningitis og sepsisbehandling.

Overvågning af bakteriæmier.

Overvågning af antibiotikaresistens.

Molekylærbiologiske metoder til diagnostik og typning,

specielt med hensyn til Legionella-infektioner.

Antibiotikaresistens.

Infektionsepidemiologi og nosokomielle infektioner

(sygehuserhvervede infektioner).

Originalartikler

Arendrup MC, Fuursted K, Gahrn-Hansen B, Schonheyder

HC, Knudsen JD, Jensen IM, et al. Semi-national

surveillance of fungaemia in Denmark 2004-2006:

increasing incidence of fungaemia and numbers of

isolates with reduced azole susceptibility. Clinical

Microbiology and Infection 2008;14(5):487-94.

Bocher S, Gervelmeyer A, Monnet DL, Molbak K, Skov

RL. Methicillin-resistant Staphylococcus aureus: risk

factors associated with community-onset infections

in Denmark. Clinical microbiology and infection

: the official publication of the European Society

of Clinical Microbiology and Infectious Diseases

2008;14(10):942-8.

Brandt CT, Holm D, Liptrot M, Ostergaard C, Lundgren

JD, Frimodt-Moller N, et al. Impact of bacteremia on

the pathogenesis of experimental pneumococcal meningitis.

J Infect Dis 2008;197(2):235-44.

Brandt CT, Simonsen H, Liptrot M, Sogaard LV,

Lundgren JD, Ostergaard C, et al. In vivo study of

experimental pneumococcal meningitis using magnetic

resonance imaging. BMC medical imaging 2008;8:1.

Cavaco LM, Frimodt-Moller N, Hasman H, Guardabassi

L, Nielsen L, Aarestrup FM. Prevalence of quinolone

resistance mechanisms and associations to minimum

inhibitory concentrations in quinolone-resistant

Escherichia coli isolated from humans and swine in

Denmark. Microbial Drug Resistance-Mechanisms

Epidemiology and Disease 2008;14(2):163-9.

Fuursted K, Arpi M, Lindblad BE, Pedersen LN.

Broad-range PCR as a supplement to culture for detection

of bacterial pathogens in patients with a clinically

diagnosed spinal infection. Scand J Infect Dis

2008;40(10):772-7.

Ibler K, Jensen KT, Ostergaard C, Sonksen UW, Bruun

B, Schonheyder HC, et al. Six cases of Aerococcus

sanguinicola infection: Clinical relevance and bacterial

identification. Scand J Infect Dis 2008;40(9):761-5.

Jensen JU, Lundgren B, Hein L, Mohr T, Petersen PL,

Andersen LH, et al. The Procalcitonin And Survival

Study (PASS) - a randomised multi-center investigator-initiated

trial to investigate whether daily measurements

biomarker Procalcitonin and pro-active

diagnostic and therapeutic responses to abnormal Procalcitonin

levels, can improve survival in intensive care

unit patients. Calculated sample size (target population):

1000 patients. BMC infectious diseases 2008;8:91.

Kjerulf A, Hansen DS, Sandvang D, Hansen F, Frimodt-

Moller N. The prevalence of ESBL-producing E-coli and

Klebsiella strains in the Copenhagen area of Denmark.

APMIS 2008;116(2):118-24.

Lester CH, Sandvang D, Olsen SS, Schonheyder HC,

Jarlov JO, Bangsborg J, et al. Emergence of ampicillin-resistant

Enterococcus faecium in Danish hospitals.

The Journal of antimicrobial chemotherapy

2008;62(6):1203-6.

Pedersen M, Brandt CT, Knudsen GM, Ostergaard C,

Skinhoj P, Skovsted IC, et al. The effect of S. pneumoniae

bacteremia on cerebral blood flow autoregulation in

rats. Journal of cerebral blood flow and metabolism :

official journal of the International Society of Cerebral

Blood Flow and Metabolism 2008;28(1):126-34.

Rasmussen RV, Kemp M, Bangsborg JM, Kjerulf

AV, Christensen JB, Bruun NE. Dyrkningsnegativ

Streptococcus pneumoniae endokarditis diagnosticeret

med polymerasekaedereaktion. Ugeskr Laeger

2008;170(39):3070.

Stolle LB, Plock N, Joukhadar C, Arpi M, Emmertsen

KJ, Buerger C, et al. Pharmacokinetics of linezolid in

bone tissue investigated by in vivo microdialysis. Scand

J Infect Dis 2008;40(1):24-9.

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