Forskning 2007 - Herlev Hospital

herlevhospital.dk

Forskning 2007 - Herlev Hospital

Forskning 2007

Medicinsk Reumatologisk Geriatrisk

Afdeling Q

Forskningsområder

Reumatologiske sygdomme med fokus på inflammatoriske

sygdomme som reumatoid artrit, Mb. Bechterew

og bindevævssygdomme.

Billeddiagnostiske metoder.

Biomarkører.

Infektionsmedicin.

Idrætsmedicin.

Betydning af behandling med biologiske lægemidler

for det det antimikrobielle immunforsvar.

Forskningsaktiviteter

Klinisk forskning, incl. kontrollerede kliniske afprøvninger

af nye behandlinger (biologiske).

Screening for tuberkulose og andre infektionssygdomme

før behandling med biologisk lægemidler.

Billeddiagnostisk forskning (MR-, ultralyds-, og CTundersøgelser).

Forskning i biomarkører, bl.a. YKL-40, IL-6 og VEGF.

Databaseforskning.

Biomekanisk forskning.

Celle- og molekylærforskning.

Originalartikler

Bird P, Ejbjerg B, Lassere M, Ostergaard M, McQueen

F, Peterfy C, Haavardsholm E, O’Connor P, Genant H,

Edmonds J, Emery P, Conaghan PG. A multireader

reliability study comparing conventional high-field

magnetic resonance imaging with extremity lowfield

MRI in rheumatoid arthritis. J Rheumatol

2007;34(4):854-6.

Combe B, Landewe R, Lukas C, Bolosiu HD, Breedveld

F, Dougados M, Emery P, Ferraccioli G, Hazes JMW,

Klareskog L, Machold K, Martin-Mola E, Nielsen H,

Silman A, Smolen J, Yazici H. EULAR recommendations

for the management of early arthritis: report of a

task force of the European Standing Committee for

International Clinical Studies Including Therapeutics

(ESCISIT). Ann Rheum Dis 2007;66(1):34-45.

Conaghan PG, Ejbjerg B, Lassere M, Bird P, Peterfy C,

Emery P, McQueen F, Haavardsholm E, O’Connor P,

Edmonds J, Genant H, Ostergaard M. A multicenter

reliability study of extremity-magnetic resonance

imaging in the longitudinal evaluation of rheumatoid

arthritis. J Rheumatol 2007;34(4):857-8.

Davis CR, Karl J, Granell R, Kirwan JR, Fasham J,

Johansen J, Garnero P, Sharif M. Can biochemical

markers serve as surrogates for imaging in knee osteoarthritis?

Arthritis Rheum 2007 Dec;56(12):4038-47.

Dohn UM, Skjodt H, Hetland ML, Vestergaard A,

Moller JM, Knudsen LS, Ejbjerg BJ, Thomsen HS,

Ostergaard M. No erosive progression revealed by

MRI in rheumatoid arthritis patients treated with

etanercept, even in patients with persistent MRI and

clinical signs of joint inflammation. Clin Rheumatol

2007;26(11):1857-61.

Dohn UM, Ejbjerg BJ, Hasselquist M, Narvestad E,

Court-Payen, Szkudlarek M, Moller J, Thomsen HS,

Ostergaard M. Rheumatoid arthritis bone erosion

volumes on CT and MRI: reliability and correlations

with erosion scores on CT, MRI and radiography. Ann

Rheum Dis 2007;66(10):1388-92.

Gjorup IE, Vestergaard LS, Moller I, Ronn AM,

Bygbjerg IC. Laboratory indicators of the diagnosis

and course of imported malaria. Scand J Infect Dis

2007;39(8):707-13.

Johansen JS, Hoyer PE, Larsen LA, Price PA,

Mollgard K. YKL-40 protein expression in the early

developing human musculoskeletal system. Journal of

Histochemistry & Cytochemistry 2007;55(12):1213-28.

Johansen JS, Brasso K, Iversen P, Teisner B, Garnero

P, Price PA, Christensen IJ. Changes of biochemical

markers of bone turnover and YKL-40 following

hormonal treatment for metastatic prostate cancer are

related to survival. Clin Cancer Res 2007;13(11):3244-9.

Keeling SO, Landewe R, van der Heijde D, Bathon J,

Boers M, Garnero P, Geusens P, El-Gabalawy H, Inman

RD, Kraus VB, Kvien TK, Mease PJ, Ostergaard M,

Ritchlin C, Syversen SW, Maksymowych WP. Testing

of the preliminary OMERACT validation criteria for

a biomarker to be regarded as reflecting structural

damage endpoints in rheumatoid arthritis clinical

trials: The example of C-reactive protein. J Rheumatol

2007;34(3):623-33.

Larsen LS, Nielsen DC, Terslev L, Amris K. Gonoroisk

monoartritis i talonavikulaerleddet. Ugeskrift for laeger

2007 Jan 22;169(4):324-5.

Lassere MN, Johnson KR, Boers M, Tugwell P, Brooks

P, Simon L, Strand V, Conaghan PG, Ostergaard M,

Maksymowych WP, Landewe R, Bresnihan B, Tak

PP, Wakefield R, Mease P, Bingham CO, Hughes M,

Altman D, Buyse M, Galbraith S, Wells G. Definitions

and validation criteria for biomarkers and surrogate

endpoints: Development and testing of a quantitative

27

More magazines by this user
Similar magazines