Die Hyperbare Sauerstofftherapie diabetischen Fußsyndroms (DFS)

Cochrane Database of Systematic ReviewsKranke P, M Bennett, I Roeckl-Wiedmann, S Debus: Hyperbaricoxygen therapy for chronic wounds . Cochrane Database ofSystematic Reviews 2007 Issue 324Copyright © 2007 The Cochrane Collaboration. Published by John Wiley & Sons,Ltd.DOI: 10.1002/14651858.CD004123.pub2 This version first published online: 26January 2004 in Issue 1, 2004Date of Most Recent Substantive Amendment: 14 October 2003This record should be cited as: Kranke P, Bennett M, Roeckl-Wiedmann I, DebusS. Hyperbaric oxygen therapy for chronic wounds. Cochrane Database ofSystematic Reviews 2004, Issue 1. Art. No.: CD004123. DOI:10.1002/14651858.CD004123.pub2.AbstractBackgroundChronic wounds are common and present a health problem with significant effecton quality of life. The wide range of therapeutic strategies for such woundsreflects the various pathologies that may cause tissue breakdown, including poorblood supply resulting in inadequate oxygenation of the wound bed. Hyperbaricoxygen therapy (HBOT) has been suggested to improve oxygen supply towounds and therefore improve their healing.ObjectivesTo assess the benefits and harms of adjunctive HBOT for treating chronic ulcersof the lower limb (diabetic foot ulcers, venous and arterial ulcers and pressureulcers).Search strategyWe searched the Cochrane Wounds Group Specialised Trial Register (searched6 February 2003), CENTRAL (The Cochrane Library Issue 1, 2003), Medline(1966 - 2003), EMBASE (1974 - 2003), DORCTHIM (1996 - 2003), and referencelists of articles. Relevant journals were handsearched and researchers in the fieldwere contacted.Selection criteriaRandomised studies comparing the effect on chronic wound healing oftherapeutic regimens which include HBOT with those that exclude HBOT (with orwithout sham therapy).Data collection and analysisThree reviewers independently evaluated the quality of the relevant trials usingthe validated Oxford-Scale (Jadad 1996) and extracted the data from theincluded trials.24