04.05.2026 Aufrufe

Newsletter_05-2026_EN

A cleanroom is a room in which the concentration of airborne particles is kept very low. The lower the proportion of airborne particles in a room needs to be, the more important technology that guarantees the purity of the air becomes. Internationally, however, cleanroom technology is not an industry but an economic sector that is essential in many industries in which particles and germs are counterproductive in production, processing and handling: Pharmaceutical industry and biotechnology, chemical industry, healthcare, food industry and cosmetics, surface and plastics technology, microelectronics and microsystems technology, optics and laser technology, aerospace technology, automotive industry and electromobility as well as research and development in general. Cleanroom technology is an important regulatory and economic factor in all future-relevant industries. All of these listed industries, and probably a few more, have no future prospects in international competition without cleanrooms, because regulatory requirements define areas of use and applications: ISO-14611 series of standards and the VDI-2083 series of guidelines, the EU GMP guidelines, the ISPE Baseline Guides and the WHO Technical Report Series-No-957, as well as several more.

A cleanroom is a room in which the concentration of airborne particles is kept very low.
The lower the proportion of airborne particles in a room needs to be, the more important technology that guarantees the purity of the air becomes. Internationally, however, cleanroom technology is not an industry but an economic sector that is essential in many industries in which particles and germs are counterproductive in production, processing and handling:
Pharmaceutical industry and biotechnology, chemical industry, healthcare, food industry and cosmetics, surface and plastics technology, microelectronics and microsystems technology, optics and laser technology, aerospace technology, automotive industry and electromobility as well as research and development in general.
Cleanroom technology is an important regulatory and economic factor in all future-relevant industries.
All of these listed industries, and probably a few more, have no future prospects in international competition without cleanrooms, because regulatory requirements define areas of use and applications:
ISO-14611 series of standards and the VDI-2083 series of guidelines, the EU GMP guidelines, the ISPE Baseline Guides and the WHO Technical Report Series-No-957, as well as several more.

MEHR ANZEIGEN
WENIGER ANZEIGEN

Verwandeln Sie Ihre PDFs in ePaper und steigern Sie Ihre Umsätze!

Nutzen Sie SEO-optimierte ePaper, starke Backlinks und multimediale Inhalte, um Ihre Produkte professionell zu präsentieren und Ihre Reichweite signifikant zu maximieren.

EN 05/26

Molecules at

your fingertips


TITLE

toolcraft AG completes state-of-the-art cleanroom

– focus on controlling molecular contamination

Molecules at your

fingertips

The new cleanroom of toolcraft

AG is consistently designed to

control molecular contamination

(Airborne Molecular

Contamination AMC).

(Photo: CAT Group)

If it concerns contamination in a cleanroom, the primary monitoring

goal is usually „particles.“ This is not surprising, as particles are present

in the air in the millions — per cubic meter, mind you. However,

there is another form of contamination that is often underestimated

during the planning and implementation of cleanrooms: molecular

contamination (Airborne Molecular Contamination AMC). This refers

to gaseous or vaporous substances, often outgassing from materials,

process chemicals, or volatile organic compounds. Molecular

contaminations are usually much smaller than particles and can lead

to uncontrollable chemical reactions, corrosion, or film formation on

surfaces.

toolcraft AG in Georgensgmünd is now commissioning a stateof-the-art

cleanroom, whose planning and implementation were

consistently focused on controlling molecular contamination. The

specialist for additive and subtractive manufacturing technologies

as well as customized automation solutions set the highest requirements

for the environmental conditions of the approximately

600-square-meter cleanroom of ISO Class 6 from the outset.

For the implementation of this demanding project, toolcraft AG

commissioned CAT Clean Air Technology GmbH from Stuttgart.

„We were looking for a partner who not only has extensive experience

in cleanroom technology but is also absolutely proficient in the

field of molecular contamination,“ says Markus Miehling, Head of

Quality Assurance and Technical Cleaning at toolcraft.

The commissioning included, among other things, the planning

and realization of the entire ventilation, cooling, dehumidification,

and measurement and control technology, the compressed air distribution,

the cleanroom enclosure areas, and the cleanroom furniture.

Additionally, the overall coordination, commissioning, regulation,

and initial qualification.

In a remarkably short time — just under a year — the project team

completed the complex construction. About 20 toolcraft employees

will now perform component-specific assemblies for the high-tech

industry in the new cleanroom in a 3-shift operation, as well as work

in the area of cooling channel and spray cleaning.

toolcraft AG, headquartered in Middle Franconia‘s Georgensgmünd,

specializes in manufacturing high-end precision components

as well as customized automation and engineering solutions.

The family-owned company, founded in 1989, employs nearly 500

staff at two locations. Additionally, toolcraft has established a strategic

foothold in Asia through a stake in PT.YPTI in Indonesia.

CAT Clean Air Technology GmbH

Motorstraße 51

D 70499 Stuttgart

Telefon: +49 711 365919937

eMail: info@catgmbh.de

Internet: http://www.catgmbh.de

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 2/73


Survey on Market

Development in

Technical Cleanliness

MAI 2026

Dear cleanroom professionals,

It’s May, and the sunshine has a positive

effect on our well-being, boosts

our energy levels and helps lift the typical

winter-economy-politics-blues.

We’ve had a look around the market and found

some interesting articles for you.

The industry of Technical Cleaning is developing more dynamically

than ever. New markets are emerging, technologies are changing

processes, and business models are noticeably shifting. Those who

do not actively evaluate these developments are increasingly making

strategic decisions in the dark.

Since 2021, the CEC has been collecting market data annually and

making developments transparent. This creates real time series and

trends that provide orientation. The current survey has been specifically

further developed and is more focused on new markets, business

models, as well as digitalization and AI.

This is exactly the added value provided by the current survey on

market development in Technical Cleaning by the Cleaning Excellence

Center (CEC).

Why participate?

The survey offers the opportunity to share your own perspective and

at the same time benefit from the results. When many companies

participate in the survey, it creates a comprehensive picture that allows

early recognition of new challenges and market requirements.

The broader the data base, the more valuable the insights for all participants.

These well-founded data can then be used for marketing,

sales, and corporate strategy.

Participants will receive the complete study afterward free of

charge, saving 120 euros.

Here’s a brief overview of the contents

of this newsletter:

> Survey on Market Development

in Technical Cleanliness

> LIFE SCIENCE READY DAYS 2026

> Cleaning pharmaceutical packaging reliably

and resource-efficiently after filling

> Cleanroom-compatible seating Systems

> When function creates atmosphere

> Synergies for high-tech cleanroom planning

> . . .

Mit freundlichem Gruß

Reinhold Schuster

Participation takes only about 10 minutes. Join now.

Here is the link to the survey: https://cec-leonberg.de/umfrage/

Deadline: 31.05.2026

CEC

D 71229 Leonberg

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 3/73


Innovations, digital transformation, shaping the future together

LIFE SCIENCE READY DAYS 2026

The LIFE SCIENCE READY DAYS are the central customer conference

of the Systec & Solutions Group and will once again bring

together specialists and executives from the life science industry on

June 9 + 10, 2026, in Karlsruhe. The event offers an established platform

for exchange, inspiration, and practical solutions around modern,

future-proof production environments.

Under the motto “Innovations, Digital Transformation, Shaping

the Future Together,” the LIFE SCIENCE READY DAYS 2026 will

focus primarily on solutions for cleanroom environments in pharmaceuticals,

biotechnology, medical technology, and related regulated

sectors. Systec & Solutions will demonstrate how processes in cleanrooms

can be made efficient, safe, and compliant through innovative

technologies, automation, and digital systems.

A special highlight of the LIFE SCIENCE READY DAYS 2026 is

the keynote by Jean-Philippe Hagmann, an internationally recognized

innovation expert and thought leader. In his lecture, Hagmann

will explore how innovation culture and digital transformation can

be successfully implemented, especially in highly regulated environments

such as the life science industry. His focus is on how companies

can drive change, integrate new technologies, and achieve

sustainable future viability through collaboration.

Highlights of the LIFE SCIENCE READY DAYS 2026:

– Inspiring keynotes on innovation, digitalization, and future

trends in life science environments

– Live demonstrations of innovative hardware and software

solutions for use in cleanrooms

– Practice-oriented workshops on digitalization, standardization,

and automation of cleanroom processes

– Best practice insights from real customer projects in regulated

environments

– Networking on equal footing with industry experts

As an exclusive conference organized by Systec & Solutions, the

event is aimed at specialists and executives from cleanroom laboratories,

pharmaceutical and biotechnological production, as well as

regulated industrial environments who want to further develop their

processes and actively shape digital transformation.

Participation & Registration

Further information about the program and registration

options can be found at:

https://crm.systec-solutions.com/en-gb/life-science-readydays-2026

Jean-Philippe Hagmann

provides insights on innovation

nd digital transformation as a

eynote speaker.

Systec & Solutions GmbH

Wilhelm-Schickard-Str. 9

D 76131 Karlsruhe

Telefon: +49 721 663510

eMail: talk@systec-solutions.com

Internet: http://www.systec-solutions.com

Insights into current trends and future strategies

in the life sciences sector.

Intensive exchange and professional discussions characterize the LIFE

SCIENCE READY DAYS and create space for new perspectives.

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 4/73


Snow instead of ultra-pure water

To ensure that any substances which may have contaminated the outside

of vials during filling do not pose a risk to humans or the environment, the

exterior surfaces of containers are increasingly being cleaned.

(Photo credit: Bausch+Ströbel)

Cleaning pharmaceutical packaging reliably

and resource-efficiently after filling

Cleaning the exterior of pharmaceutical containers such as bottles, vials and cartridges

after filling prevents any adhering product residues from becoming a danger

to humans and the environment. This process, which is traditionally liquidbased,

consumes enormous amounts of energy and water and incurs high costs.

In order to offer a dependable but more resource-friendly solution, a leading manufacturer

of fill & finish machines participated in a joint project to investigate

the suitability of the quattroClean snow jet technology. The results confirm that

the sustainable cleaning process meets all the requirements of the pharmaceutical

industry. A basic validation carried out in parallel simplifies the approval of

the process in compliance with FDA and GMP regulations.

Taking on the challenges of the global market

and meeting them with the best technical

and most cost-effective solutions:

this is the corporate goal that has guided

Bausch+Ströbel SE + Co. KG since 1967 in

the design, manufacture, and sale of packaging

and production systems for the pharmaceutical

and related industries. What

started off with four employees has since

grown into an international group of companies

with a workforce of around 2,800 staff

and an export share of over 90%, making it

Up till now, external cleaning has generally

been a liquid-based process involving spraying

the containers with ultra-pure water and

subsequently drying them with clean compressed

air. This requires large quantities

of water to be treated in an energy-intensione

of the world’s market leaders in the field

of pharmaceutical packaging.

High-tech packaging solutions including

external cleaning after filling

High-quality pharmaceuticals in liquid and

powder form are filled into vials, bottles, syringes,

or cartridges on customer-specific

filling and finishing lines in a fully automated

process. This starts with cleaning and

sterilizing the containers and continues

through to labeling or syringe assembly.

“Due to the trend towards the use of increasingly

potent active ingredients, there

is a risk that the exterior of the containers

could be contaminated with a potentially

hazardous substance after filling. We are

therefore seeing a growing demand for solutions

to clean the outside of containers after

the filling process. Not only do ever-stricter

cleaning requirements have to be met,

but the reliable removal of product residues

must also be proved,” reports Werner Iländer,

Group Manager of Research, Technology

and Pharma Services at Bausch+Ströbel.

Dry snow jet technology instead

of ultra-pure water

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 5/73


ve process and, depending on the product

being filled, to be disposed of as hazardous

waste. This not only results in high operating

costs for customers but is also a wasteful

use of drinking water, which has already

become scarce in some regions of the world.

“For these reasons, we looked around for

an alternative cleaning method that would

make this process more cost-efficient and

resource-friendly, as well as having a lower

CO2 footprint. We have been working with

the dry quattroClean snow jet cleaning

technology from acp systems for some time

and know that very high standards of cleanliness

can be achieved, depending on the

substance to be removed. However, we had

no valid data on the material compatibility

of the process,” says Werner Iländer, describing

the initial situation.

QuattroClean snow jet cleaning is a dry

process for full-surface and localized applications

that can be easily integrated into fully-automated

production lines. The cleaning

medium is liquid, recycled carbon dioxide,

which is a by-product of industrial processes

and used, among others, in the food

industry. The liquid CO2 is guided through

a wear-free two-substance ring nozzle and

expands on exiting to form fine snow crystals.

These are bundled by a separate jacket

jet of compressed air and accelerated to

supersonic speed. The easily-focused jet of

compressed air and snow develops a combination

of thermal, mechanical, solvent, and

sublimation effects on impacting on the

surface to be cleaned, which makes it highly

effective. The removed contaminants are

then extracted in the compact cleaning cell,

thus preventing re-contamination of the

product and contamination of the surroundings.

Since the crystalline carbon dioxide

sublimates completely during the process,

the cleaned residue-free surfaces are dry,

thereby eliminating the need for costly and

energy-intensive rinsing and drying steps.

With the aim of significantly reducing resource

consumption in the cleaning of medical and

pharmaceutical products, the material compatibility

and cytotoxicity of the dry quattroClean

snow jet cleaning technology was successfully

investigated in a joint project.

(Photo credit: acp Systems)

Joint project provides

the necessary evidence

Examination results with different test substances before and after cleaning.

(Image source: Bausch+Ströbel)

Microscope images of vials with existing damage show no change in the

defects before (left) and after (right) worst-case cleaning with the CO2 snow.

(Photo credit: Fraunhofer IPA)

Bausch+Ströbel therefore did not hesitate

to participate in a joint project funded by

Invest BW involving five industrial partners

as well as Fraunhofer IPA and the NMI Natural

and Medical Sciences Institute at the

University of Tübingen. In the project, the

material compatibility and cytotoxicity of

the cleaning technology was investigated

on various product surfaces typically found

in the medical and pharmaceutical sectors.

“This project was primarily about proving

that the mechanical forces of the snow

crystals do not alter, impair, or damage the

surface in any way. It was also important to

establish whether the thermal stress and/or

the chemical properties of carbon dioxide

affect the surfaces or biocompatibility of the

containers, for example by releasing cytotoxic

material components,” explained the

group manager.

In addition to glass vials, test specimens

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 6/73


made of stainless steel 1.4301 and 1.4305

with different surface finishes, as well as polyetheretherketone

(PEEK), polyether (PE),

polyoxymethylene (POM), nitinol, and cobalt-chromium

were included in the studies.

To evaluate the test series, Fraunhofer

IPA examined the surfaces of the test specimens

microscopically (light and/or scanning

electron microscope) in their initial

state and after cleaning. The dry jet cleaning

process was carried out under worst-case

conditions, i.e. the middle section and edges

of the test specimens were continuously

irradiated with CO2 snow at a high pressure

of twelve bars for ten seconds. During the

subsequent microscopic examination of the

glass vials, no cracking was detected, and no

propagation of existing cracks was observed.

With the aid of a fluorescent penetrant,

it was also possible to demonstrate that the

snow crystals did not cause any additional

stress in the glass. Likewise, the abrupt exposure

to cold and the subsequent warming

of the vials to ambient temperature did not

result in the formation of any micro cracks.

Furthermore, in vitro cytotoxicity tests in

accordance with DIN EN ISO 10993-12:

2021-05 and DIN EN ISO 10993-12: 2021-

08 confirmed that the CO2 snow does not

impair cell vitality in any way. The VOC and

SVOC analyses carried out according to ISO

16017-1 yielded Tenax values within or below

the measurement limits.

GMP- and FDA-compliant process

The process therefore meets all the requirements

of the pharmaceutical industry in this

field; it is also compliant with GMP and FDA

in terms of material compatibility, meaning

that basic validation has already been achieved.

“In this project, we were able to generate

the key data for our customers and develop

a basic solution. The next step will be

to implement this in a market-ready product

that will significantly reduce operating costs

and resource consumption in external cleaning

for specific applications,” adds Werner

Iländer.

acp systems AG

Berblingerstraße 8

D 71254 Ditzingen

Telefon: +49 7156 480140

eMail: info@acp-systems.com

Internet: http://acp-systems.com

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe DE 05-2023

Seite 7/103


A major milestone in propelling industry into the ångström era

Imec receives the world’s most advanced

High NA EUV system

– Imec announces the arrival of the ASML EXE:5200, the world’s most advanced

High NA EUV lithography system, in its 300mm cleanroom in Leuven.

– Operating the High NA EUV system in direct connection with state-of-the-art metrology and patterning

equipment/materials accelerates learning cycles to unlock the performance needed for sub-2nm logic

and future memory technologies, supporting the rapidly scaling AI and high-performance computing (HPC) markets.

– “With this strategic capability, imec reinforces its central role in launching the industry into the ångström era.

The tool is also set to play a pivotal role in solidifying Europe’s position as a leader in advanced

semiconductor R&D in the decades to come.” – Luc Van den hove, imec.

On March 18, 2026 imec, a world-leading

research and innovation hub in

advanced semiconductor technologies,

announced the arrival of the

ASML EXE:5200 High NA EUV lithography

system, the most advanced

lithography tool available today. With

this strategic milestone, imec reinforces

its position as the industry’s

launchpad into the ångström era, giving

its global partners ecosystem unparalleled

early access to the next generation

of chip-scaling technologies.

Integrated directly with a comprehensive

suite of patterning and metrology

tools and materials, the High NA EUV

system will empower imec and its ecosystem

partners to unlock the performance

needed to pioneer sub-2nm

logic and high-density memory technologies

that will fuel the rapid growth

of advanced AI and high-performance

computing.

Luc Van den hove, CEO of imec: “The past

two years have marked an important chapter

for High NA (0.55NA) EUV lithography,

with imec and ASML joining forces with the

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 8/73


ecosystem in its joint High NA EUV Lithography Lab in Veldhoven

(The Netherlands) to pioneer High NA EUV technology. With the

installation of the EXE:5200 High NA EUV lithography system into

our 300mm cleanroom in Leuven (Belgium), we aim to bring these

High NA EUV patterning technologies to an industry-relevant

scale and to develop the next-generation High NA EUV patterning

use cases. Its unmatched resolution, improved overlay performance,

high throughput, and a new wafer stocker that improves process stability

and throughput, will give our partners a decisive advantage in

accelerating the development of sub-2nm chip technologies. As the

industry moves into the ångström era, High NA EUV will be a cornerstone

capability, and imec is proud to lead the way by offering its

partners the earliest and most comprehensive access to this technology.”

This milestone is a key element of imec’s five-year strategic partnership

with ASML supported by the EU (Chips Joint Undertaking

and IPCEI), the Flemish government, and the Dutch government.

Luc Van den hove: “As an integral part of the EU funded NanoIC pilot

line, the tool is set to play a pivotal role in strengthening Europe’s

position as a leader in advanced semiconductor R&D in the decades

to come.”

Having the ASML EXE:5200 High NA EUV lithography system in

imec’s cleanroom firmly positions imec as the most comprehensive

development environment for advanced patterning. Imec’s deep

ecosystem collaboration with leading chip manufacturers, equipment,

material and resist suppliers, mask companies, and metrology

experts will allow us to ramp up learning cycles and enhance process

stability to develop and demonstrate cutting-edge patterning for

next generation logic and memory device technology, driving breakthroughs

that will shape the future of advanced computing and AI in

the years to come.

Christophe Fouquet, CEO of ASML: “Imec’s installation of the

EXE:5200 marks an important step into the ångström era. Together,

we’re accelerating High NA EUV extendibility for the next generations

of advanced memory and compute.”

Imec anticipates the EXE:5200 High NA EUV lithography system

to be fully qualified by Q4 2026. In the meantime, the joint

ASML-imec High NA EUV lithography Lab in Veldhoven will remain

operational, ensuring continuity in the High NA EUV R&D activities

for imec and its ecosystem partners.

IMEC Belgium

BL 3001 Leuven

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe DE 05-2023

Seite 9/103


EU is funding SPINS with an amount of € 50 million

Semiconductor-based

Quantum Pilot Line ‘SPINS’

launched with EU support

In April, ‘SPINS’ (Semiconductor Pilot line for Industrial Quantum NanoSystems)

was launched, one of the 6 European quantum pilot lines. Coordinated by

imec, the consortium brings together 25 European RTOs, industry partners, and

academic research groups to strengthen Europe’s leadership and sovereignty in

this strategically important domain. The €50 million SPINS pilot line project has

been made possible through the co‐funding support from the European Union’s

Chips Joint Undertaking (Chips JU) and the national and regional authorities of

the participating Member States. Fraunhofer IPMS plays a central role within

SPINS in the high-resolution structuring of qubit and processor elements.

tion navigation systems.

However, a gap remains between current

quantum research and manufacturable

quantum processors to enable significant

quantum applications. Scaling the number

of stable qubits (to as much as one billion)

Fraunhofer IPMS plays a central role within SPINS in the high-resolution structuring

of qubit and processor elements. © Fraunhofer IPMS

Quantum computing has become a highly

strategic domain with economic and societal

relevance rising sharply. Applications

vary from breakthroughs in drug

discovery and materials science to ultrasecure

communications and next-generais

key to building reliable and fault-tolerant

quantum computers.

Given the technological complexity, including

cryogenic operation, ultraprecise

control electronics and highly specialized

fabrication processes, and given the strategic

importance of quantum chips, the EU

Chips Act has established six complementary

quantum pilot lines, each focused on a

distinct hardware platform and collectively

advancing quantum technologies in the

space of quantum computing, communications

and sensing. Within this portfolio,

SPINS is the pilot line dedicated to semiconductor‐based

spin qubits, with a primary

focus on delivering quantum chips for quantum‐computing

applications.

Imec coordinates this new pilot line efforts

and leads the European consortium of

25 partners, ranging from RTOs like Fraunhofer,

VTT and CEA-Leti, industry (both

large enterprises like Infineon and Siltronic

as well as SMEs and startups) and academic

groups (like TU Delft and University of Jyväskylä),

bringing in complementary knowledge

and skills, with the goal of translating

the strategic framework of the EU Chips Act

into concrete actions.

The first actions of the SPINS-consortium

include process and design optimization

to establish a robust foundation for scalable,

stable, and high-performing spin qubits,

all on three different technology platforms:

Si/SiGe, Ge/GeSi, and SOI. SPINS aims to

establish a lab-to-fab route for this technology

via Multi-Project Wafers (MPW) and

standardized quantum Process Design Kits

(PDKs), which lower entry barriers for startups

and SMEs in semiconducting quantum

technology and lay the foundations for European

companies to build quantum knowhow

early on.

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 10/73


Fraunhofer IPMS within the SPINS pilot line

Fraunhofer IPMS plays a central role within SPINS in the high-resolution

structuring of qubit and processor elements. All lithography

steps requiring resolutions beyond the capabilities of optical

methods are performed at Fraunhofer IPMS. This enables precise,

reproducible patterning, which is essential for the functionality and

scalability of Si/SiGe-based quantum chips. In addition, Fraunhofer

IPMS makes key contributions to process stability and maturity

across the pilot line by providing state-of-the-art cleanroom infrastructure

designed for reproducible, scalable qubit fabrication. Processes

at Fraunhofer IPMS are designed to support both Si/SiGe and

Ge/SiGe platforms, securing multiple technologically complementary

pathways within the SPINS consortium. Furthermore, the expertise

of Fraunhofer IPMS bridges to activities within the EU project

QLSI2, where migration to high-resolution lithography and 300-mm

wafers is being explored. This prepares the transfer of SPINS pilot

line results to a future 300-mm CMOS line at an early stage.

In this way, Fraunhofer IPMS combines leading research expertise

with industrial process readiness, significantly strengthening Europe’s

technological independence in semiconductor quantum technology.

European quantum pilot lines

Complementary tracks of the European quantum efforts, next to

the semiconductor-based pilot line, include pilot lines on photonics

for quantum ‘P4Q’ (coordinated by University of Twente,

NL) - to which imec is also contributing, ion trap qubits ‘CHAMP-

ION’ (coordinated by SAL, AT), superconducting qubits ‘SUP-

REME’ (coordinated by VTT, FI), diamond quantum chips ‘DI-

REQT’ (coordinated by CNR, IT) and neutral atoms ‘Q PLANET’

(coordinated by Pasqal, FR).

Fraunhofer-Institut für Photonische Mikrosysteme IPMS

D 01109 Dresden

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe DE 05-2023

Seite 11/103


Uni Siegen

becomes a beacon

for intelligent

sensor technology

The University of Siegen is significantly expanding its infrastructure

for modern sensor technologies: With the WI-

SENT pilot line, a state-of-the-art environment for the development

of intelligent sensors is being created in the new

INCYTE research building. The project has a total volume of

4.7 million euros.

© Sascha Hüttenhain

Glaringly bright light, absolutely clean air, researchers in blue fullbody

suits: The cleanroom area forms the technological heart of the

new INCYTE research building at the University of Siegen. A stateof-the-art

laboratory environment in which intelligent sensors can

be manufactured, tested and developed into prototypes. The WI-

SENT pilot line is now significantly expanding the infrastructure

once again: five new high-tech systems and additional process options

are taking research and development work in the clean room to

a new level. The project is being funded by the ERDF program with

EU funds amounting to 4.7 million euros.

Partner for the industry

„The new systems not only complement the existing infrastructure,

they also enable fundamentally new process and analysis methods

and, together, create truly outstanding technological conditions. A

few years ago, we would never have dared to dream of coating or removing

individual atomic layers of selected materials in a targeted

manner,“ says Dr. Andreas Bablich, Head of Technology at WISENT.

WISENT stands for „Westphalian Intelligent Sensor Integration Pilot

Line“ - an end-to-end high-tech production line that covers the

entire development process: from the initial idea to chip and component

design, sensor production, integration into complex systems

and system-specific software development. Not only researchers,

but also companies and start-ups can make use of the infrastructure

and scientific expertise at INCYTE.

„Collaboration with industry is very important to us. We want to

create a low-threshold offer to implement feasibility studies and initial

demonstrators for new sensor concepts without companies having

to invest in cost-intensive large-scale equipment themselves,“

explain Paul Kienitz, who is responsible for operating the new cleanroom

facilities at WISENT, and Maurice Müller, who played a key

role in acquiring the pilot line.

Sensors for medicine, industry and the environment

The new infrastructure opens up a wide range of possibilities for

intelligent sensor technology: one example is 3D image sensors, in

Working together on the WISENT project: Matthias Weber,

Dr. Andrii Nehrych, PD Dr. Andreas Bablich, Prof. Dr. Peter Haring Bolívar,

Prof. Dr. Benjamin Butz, Prof. Dr. Ivo Ihrke, Prof. Dr. Michael Möller,

Prof. Dr. Bhaskar Choubey, Paul Kienitz, Moin Diwan (from left to right).

© Dirk Manderbach

The cleanroom at INCYTE may only be entered with special protective

clothing. First row: Prof. Dr. Bhaskar Choubey, Paul Kienitz,

PD Dr. Andreas Bablich, Moin Diwan, second row: Prof. Dr. Michael Möller,

Matthias Weber, Prof. Dr. Peter Haring Bolívar,

third row: Prof. Dr. Benjamin Butz, Prof. Dr. Ivo Ihrke, Dr. Andrii Nehrych

(from left to right). © Dirk Manderbach

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 12/73


© Dirk Manderbach

which microscopically small structures - such as lenses or

other optical elements - can be printed directly onto the

sensor chips using modern production technologies. This

allows the incident light to be captured and processed particularly

efficiently. Novel materials also play an important

role. For example, researchers are working with extremely

thin semiconductor layers or two-dimensional materials

such as graphene.

„The integration of special AI hardware makes these

high-performance sensors even more powerful,“ explains

Dr. Bablich. „You get a kind of integrated little brain that evaluates

the huge amounts of data from the 3D pixels or graphene

layers directly on site in fractions of a second.“ This

results in extremely compact systems that perceive the environment

in precise 3D depth and immediately interpret

the information obtained. Areas of application include autonomous

driving, robotics and wearables for fall detection,

which can react in real time.

Plant analysis and biomarker recognition

Other applications range from agriculture to medicine. In

future, drones equipped with special image sensors could

analyze plants from the air and determine the health status

of fields based on reflected light signals. In medical technology,

Prof. Dr. Peter Haring Bolívar‘s team is working on

highly sensitive sensors that can detect the smallest molecules

- so-called biomarkers. This could enable diseases

such as skin cancer to be diagnosed much more effectively

in future than with current laboratory methods.

With the Center for Sensor Systems (ZESS), the University

of Siegen has already had an internationally recognized

platform for research into this key area of technology for

many years. The WISENT pilot line in the new INCYTE research

building will enable the university to further expand

its role as an innovation driver for intelligent sensor systems.

„The combination of state-of-the-art infrastructure, interdisciplinary

research and close cooperation with industry

characterizes our location. This makes us the central point

of contact in NRW for all questions relating to software,

hardware and system integration in sensor technology,“ says

Andreas Bablich.

Universität Siegen

D 57076 Siegen

NEWSLETTER | Ausgabe EN 05-2026

Seite 13/73


Wafer Exchange For Ferroelectric Memory

Materials Within the FAMES Pilot Line

CEA-Leti and Fraunhofer IPMS have successfully completed the first exchange

of ferroelectric memory wafers within the FAMES Pilot Line, marking a pivotal

milestone in establishing a shared European platform for advanced embedded

non-volatile memory technologies. Launched in December 2023 and coordinated

by CEA-Leti, the five-year initiative has demonstrated the viability of circulating

complex material stacks across some of its leading research fabs.

The collaboration has been first focused on

the processing and electrical characterization

of hafnium-zirconium oxide (HZO)

ferroelectric capacitor stacks. Utilizing the

combined 300 mm CMOS cleanroom capabilities

of both institutes, the wafers were

circulated in short process loops to enable

joint evaluation of materials, electrode configurations,

and device behavior.

The work also validated the wafer exchange

and contamination-control protocols

implemented in the Pilot Line, demonstrating

that complex material stacks can be

processed reliably across multiple advanced

semiconductor facilities, on all wafers.

The entire process adhered to standardized

contamination control procedures, verified

through VPD-ICP-MS (Vapor Phase

Decomposition – Inductively Coupled Plasma

Mass Spectrometry) and TXRF (Total

Reflection X-Ray Fluorescence) analytics.

Devices were evaluated using a FeCAP array

test vehicle designed by CEA-Leti, with

electrical characterization performed via

the PUND (Positive-Up-Negative-Down)

methodology to isolate true ferroelectric

switching from parasitic effects.

Accelerating the Path Toward

System-Level Application

„The successful wafer exchange marks an

important step toward a joint European

material testing platform for ferroelectric

memories,“ said Dr. Wenke Weinreich, Division

Director of Fraunhofer IPMS’ Center

Nanoelectronic Technologies, a member of

the 11-member consortium. „By combining

our processing expertise with CEA-Leti’s

CMOS integration capabilities, the pilot

line provides a powerful environment for

evaluating new ferroelectric stacks and accelerating

their path toward system-level

applications.“

Initial experimental results have already

yielded critical insights. The team screened

various electrode materials to enhance

performance, finding that titanium nitride

Illustration of HfO₂-based ferroelectric devices enabling scalable, CMOS-compatible non-volatile

memory. The architecture supports integration in both front-end (FeFET) and back-end memory

structures, while opening pathways to advanced ferroelectric functionalities such as multiferroic,

pyroelectric, and tunable RF devices. © Fraunhofer IPMS

(TiN) bottom electrodes significantly outperform

tungsten (W). In reliability tests,

TiN exhibited lower failure rates after 10⁷

field cycles at 4 MV/cm. Furthermore, clear

cross-split effects were observed across different

electrode configurations, confirming

the sensitivity of the test vehicles to process

variations.

Seamless Exchanges Across FAMES’ Sites

„This first exchange between CEA-Leti and

Fraunhofer IPMS demonstrates that shared

process flows, test vehicles, and characterization

environments can work seamlessly

across FAMES’ sites,“ noted project Coordinator

Dominique Noguet. „Establishing reliable

wafer loops between leading research

fabs is essential for accelerating ferroelectric

memory development.“

Looking ahead, the wafer loops lay the

groundwork for broader collaborative development.

Upcoming phases will integrate

HfO₂-based ferroelectric stacks from

Fraunhofer IPMS into CEA-Leti CMOS

processes, followed by array-level evaluations

of state-of-the-art memory technologies

embedded in the upcoming Global-

Foundries’ 22nm FDX® Memory Advanced

Demonstrator Multi Project Wafers shuttle

prepared by CEA-Leti. The roadmap also

includes studies on electrode process variations,

long-term reliability, and back-endof-line

integration approaches.

In parallel, Fraunhofer IPMS recently

completed a first chip tape-out using GlobalFoundries’

22nm FDX® technology and

initiated research on algorithm-based AI

compute-in-memory accelerator architectures

built on these ferroelectric technologies.

Together, these efforts advance the core

mission of the FAMES Pilot Line: to provide

a unified European platform for developing

and validating emerging memory technologies—including

OxRAM, MRAM, FeRAM,

and FeFET. By enabling collaborative material

development and standardized characterization,

the initiative aims to strengthen

Europe’s capacity to design and manufacture

the low-power, next-generation chip architectures

required for the future of computing.

Fraunhofer-Institut für

Photonische Mikrosysteme IPMS

D 01109 Dresden

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 14/73


Highest hygiene: Stainless steel,

rust-free, for tray handling systems

Granulation systems with stainless steel components

ensure efficient granulation. © L.B. Bohle

Tablets are among the most widespread forms of medication,

nutraceuticals, and dietary supplements. Easy to dose,

convenient to transport, and to take with a sip of water whenever

needed, they ensure precise release of active ingredients.

Their production demands the highest standards:

consistently high quality and compliance with all regulations

for process and food safety must be balanced with resource-efficient,

sustainable manufacturing and cost-effectiveness.

Tablet presses, which can be flexibly used for

batch and high-volume production, automate and control

the complex process from powder to finished tablet. The

heart of these production lines are tablet presses, as they

significantly contribute to the quality, safety, and economic

efficiency of the products. For all parts in contact with the

product, high-quality stainless steel, corrosion-resistant, is

mandatory.

Diverse types of tablets – single or multilayer, coat-core, effervescent,

or lozenges – as well as various tablet shapes require tailored

equipment concepts. The range of tablet presses extends from laboratory

eccentric presses for initial feasibility studies, through R&D

rotary presses, standard single and multi-station rotary presses, to

high-performance double rotary presses. Fully integrated systems in

enclosed design with containment features for highly active or toxic

substances encompass the entire production process, from material

feeding, dosing, granulation, to tableting and quality control, packaging

into blisters or cans, as well as cleaning, retooling, and maintenance

of all system components.

Fundamental components of every tablet press include hoppers,

feed shoes, dies, and punches. Besides the active pharmaceutical

ingredient, tablets usually contain additional excipients such as binders,

lubricants, and flow regulators. A balanced interplay of these

components is crucial for the flow properties of the material. Granulates

have better flow characteristics compared to powders and

can therefore be dosed more effectively. Various processes such as

fluidized bed, vertical, high-shear, or double-screw granulation are

used industrially to produce granulates for tablets. Batch granulators

combine three process steps in one vessel: mixing, vertical or highshear

wet granulation, and drying.

Up to one million tablets per hour

The use of stainless steel in tablet manufacturing equipment significantly

contributes to the quality, safety, and cost-effectiveness of the products.

© L.B. Bohle

The powder or granulate mixture is fed into the hopper, which distributes

it into openings called dies, determining the later tablet shape,

on a rotating die wheel. Die segments can replace the rotor to enable

significantly more tablet stations at the same press size. In the dies,

upper and lower punches compress the material with increasing

force into the final tablet shape. Often, tablets are also marked with

a break line and a logo here.

Sensors measure the pressing force and ensure consistent quality

by monitoring weight, hardness, thickness, and breaking strength

of each individual tablet. Some press models address the high load

on tooling with heavy-duty profile heads to minimize wear. The

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 15/73


In integrated plant concepts for tablet manufacturing, product-contact

components made of stainless steel corrosion-resistant provide the

necessary product safety across processes. © L.B. Bohle

For equipment enclosures,

stainless steel is the guarantee

of sustainably highest hygiene

and reliable durability in 24/7

operation. © FETTE Compacting

When it comes to stainless steel

tablet presses, product quality and

process safety are the focus.

© FETTE Compacting

finished tablet is pushed upward from the die by the lower punch

and transported into a collection container or onto a conveyor belt

by a shuttle. High-performance presses process all types of granulate

and viscous products at high speed using changeable die discs. They

can produce over a million single-layer tablets in various shapes or

up to 500,000 multilayer tablets per hour.

Protection against emissions through containment features

Stainless steel, due to its corrosion resistance and good processing

properties, is a standard material for numerous components in

tablet manufacturing equipment. © WZV/ERWEKA

High-quality stainless steel, rust-free, meets the strictest

hygienic requirements through its smooth, abrasion-resistant,

and easy-to-clean surface. © L.B. Bohle

Ensuring process safety also involves protecting people and the environment

from emissions. Product changeovers require the press

to be thoroughly cleaned beforehand to prevent cross-contamination.

Increasing demands for active ingredient safety and process

control are reflected in various containment features in tablet production.

Modern tablet presses are designed with dust-tight basic

equipment and operate under vacuum to prevent active ingredient

escape. When processing highly active or toxic substances, a fully

enclosed system with complete containment features is necessary.

The five-stage containment pyramid from the International Society

for Pharmaceutical Engineering (ISPE), known as the Occupational

Exposure Band (OEB), is used to classify the hazard level of the substances

used.

In practice, for products rated OEB 3 and above, fully automated

tablet production from system filling to dust-minimized tablet

discharge is considered the minimum standard. Glove boxes, leakproof

transfer systems, and efficient dry and wet cleaning technologies

complement containment solutions. From OEB 4 onwards,

Wash-in-Place (WIP) procedures significantly reduce the workload

for machine operators during cleaning. For hazard class OEB 5, the

highest safety requirements in production and personnel protection

are ensured by a highly complex high-containment system for

the entire plant: including a closed material handling system with

fully enclosed, integrated production lines from automatic material

feeding, tableting, in-process quality control, comprehensive dust

emission control, air management, and Wash-in-Place technology.

For highly active active pharmaceutical ingredients, whose demand

is rapidly increasing due to new therapies, such as in oncology,

continuous direct compression in a closed system is considered a

future-oriented solution.

Cross-process use of stainless steel

In tablet manufacturing systems, components made of stainless

steel – like this measuring machine – provide reliable protection against

emissions and cross-contamination. © FETTE Compacting

Given strict requirements for hygiene and purity of the production

environment according to ISO standards or Good Manufacturing

Practice (GMP), stainless steel is indispensable for all product-con-

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 16/73


The use of stainless steel (stainless) in this fully automatic

tablet hardness tester guarantees a hygienic production

environment. © WZV/ERWEKA

tact components in tablet production lines. High-quality stainless

steel, such as grades 1.4404 and 1.4435, meets the strictest hygienic

standards due to its smooth, wear-resistant, and easy-to-clean surface.

The durable surface quality of this inert material withstands

corrosive environments, high pressures, and temperatures over the

long term. Particularly, austenitic stainless steel 1.4404 with 2 to 2.5

percent molybdenum content is a standard material for many components

in integrated production lines due to its corrosion resistance

and good processing properties.

Electropolished surfaces with defined roughness prevent particle

adhesion, further increase corrosion resistance, and withstand

mechanical stresses. Appropriately designed stainless steel components

in tablet systems are fully WIP-compatible and can be cleaned

repeatedly without residue. In integrated tablet manufacturing

systems, product-contact components made of corrosion-resistant

stainless steel provide the necessary process safety and reliable protection

against emissions and cross-contamination across the entire

process chain.

From IBC containers for raw material and product storage, to

granulators, mixers, hoppers, dies, and punches, up to conveyor

belts, sampling systems, waste disposal units with metal detectors,

sorting and counting systems, high-quality stainless steel is standard

practice. It is also used in dust extraction filters, air filters, cleaning

systems, sensor and control housings, and plant enclosures, ensuring

maximum hygiene and reliable durability in 24/7 operation.

Warenzeichenverband Edelstahl Rostfrei e.V.

D 40237 Düsseldorf

Alles für Ihren Reinraum

aus einer Hand

Bekleidung & Handschuhe

Tücher & Swaps

Reinigungsgeräte- & mittel

Dispenser

Partikelmessgeräte

Staubbindematten

HANS J. MICHAEL GmbH, Hart 11, 71554 Weissach im Tal

hjm-reinraum.de | Tel. 07191/9105-0 | office@hjm-reinraum.de

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe DE 05-2023 Seite 17/103


Why the right office chair contributes more to process safety than often assumed

Cleanroom-compatible seating systems

In cleanrooms, every detail is crucial. Air purity, material behavior,

cleanability, and electrostatic safety must be precisely coordinated

to ensure stable processes and consistent product quality. While

machines, materials, and process media are usually thoroughly evaluated

and monitored, one element is often underestimated in daily

practice: the work chair.

However, a cleanroom chair is much more than just a seat. It is

located in close proximity to the process, interacts directly with the

operating personnel, and influences both hygiene and ergonomics

as well as process stability. Those who think holistically about cleanroom

workstations should therefore consider seating systems under

the same criteria as other technical components.

Cleanroom workstations impose special requirements

Depending on the industry — such as semiconductor manufacturing,

medical technology, pharmaceuticals, or precision mechanics — uncompromising

requirements apply in the cleanroom. Components

used in these environments must behave controllably, be safely cleanable,

and must not introduce additional contamination sources.

For seating systems, this means specifically: they must not only

be ergonomic but also designed structurally and materially for cleanroom

use. Particularly in sensitive areas according to DIN EN ISO

14644-1, aspects such as particle emission, cleanability, material stability,

and ESD safety play a central role.

Hygienic Design: Cleanability begins in the construction

A cleanroom-compatible work chair must be designed so that surfaces

can be cleaned quickly, thoroughly, and safely. This is precisely

where the principle of Hygienic Design comes into play.

For Bimos, this means for a cleanroom chair like the TEXON:

– Smooth, closed surfaces

– Minimized joints and gaps

– Rounded transitions

– Sealed mechanisms

– Easily accessible cleaning areas

Especially in the cleanroom, open mechanisms, hard-to-reach interspaces,

or unsuitable surfaces can lead to the accumulation of particles,

residues, or lubricants. A design with a clean, reduced form

language is therefore not only a matter of aesthetics but also a crucial

contribution to process safety.

The TEXON demonstrates this approach particularly clearly:

The Clean Cover additionally protects the mechanism, the closed

design supports cleanability, and reduces potential weak points during

daily use.

Material durability is not a detail but a necessity

In addition to construction, material choice also plays a central role.

In cleanrooms, work chairs are regularly cleaned with alcohol-based

or oxidative disinfectants. Materials must therefore remain permanently

resilient — without swelling, dispersing, or altering their surface.

With Skintec, Bimos has developed a covering material specifically

designed for these requirements. The material is disinfectantresistant,

easy to clean, has a closed surface, and at the same time

offers particularly comfortable seating.

This combination is especially critical in practice: In the cleanroom,

it is not enough for a material to be merely hygienic. It must

also withstand continuous use — under mechanical stress, during

regular disinfection, and over long usage cycles.

Skintec was therefore developed to be not only functional but

also durable and economical. The surface remains dimensionally

stable, resistant to common disinfectants, and offers a high-quality

tactile feel. For companies, this means less material fatigue, longer

service life, and an overall more stable workplace standard.

Particle control also begins with sitting

Operating personnel are among the largest sources of particles in

the cleanroom. That is why the work chair influences particle control

more than often assumed.

Seating systems affect, among other factors:

– Movement patterns at the workstation

– Wear on contact surfaces

– Stability of working positions

– Material behavior during daily use

An ergonomically unfavorable chair often leads to frequent position

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 18/73


Therefore, modular seating systems are increasingly important. For

example, on the TEXON, seat and backrest cushions can be quickly

and easily replaced as exchangeable pads. This not only reduces

downtime but also facilitates cleaning, maintenance, and long-term

use.

This is a real advantage especially in sensitive production environments:

individual components can be replaced without having

to replace the entire seating system. This saves resources, reduces

costs, and supports a more sustainable workplace design.

Ergonomics is also a cleanroom issue

Ergonomics is still often reduced in the cleanroom to “seating comfort.”

In reality, it is a key factor for concentration, process safety, and

work quality.

Anyone working in controlled environments for extended

periods needs a seating solution that:

– Supports an upright, stable posture

– Distributes pressure evenly

– Allows movement without creating instability

– Can be used intuitively and without distraction

changes, unnecessary compensatory movements, and potentially

increased particle disturbance. Therefore, cleanroom-compatible

seating solutions should be designed not only with low emissions

but also with ergonomic considerations.

The TEXON was developed precisely from this perspective. Its

movement mechanism supports dynamic sitting and promotes a

stable, ergonomically sensible working posture — without complicated

adjustment logic. This helps employees focus on their tasks and

reduces unnecessary movement impulses in the sensitive work environment.

ESD safety is indispensable even in the cleanroom

In many cleanroom applications — especially in electronics and semiconductor

manufacturing — not only cleanliness but also electrostatic

safety is critical. Uncontrolled discharges can damage sensitive

components or disrupt processes.

Therefore, cleanroom chairs must often be designed to be not

only particle-safe but also electrostatically safe. Bimos consistently

considers these requirements: In the TEXON, all relevant components

are conductive and tailored for use in sensitive high-tech environments.

Particularly noteworthy is a technological advancement long

considered challenging in the industry: conductive materials in light

color variants. While ESD-capable plastics have so far mostly been

realized only in dark shades, this development opens new possibilities

for light, hygienic-looking cleanroom workstations — without

compromising functionality.

Modularity and maintenance: An often underestimated advantage

Another important aspect in the cleanroom is how components

can be maintained, replaced, and used long-term. Any unnecessary

maintenance or complete replacement can interrupt processes and

incur additional costs.

This shows clearly that cleanroom chairs must not only be “cleanroom-compatible”

but also workplace-appropriate. Only when hygiene,

technology, and ergonomics are considered together does a

workplace truly meet the requirements of modern cleanroom production.

Thinking about cleanroom workstations holistically

A work chair is not a secondary element in the cleanroom. It is part

of a sensitive overall system and should be evaluated accordingly.

Construction, material, cleanability, ESD capability, ergonomics, and

maintenance all influence how stable and safe a workstation functions

in everyday use.

With solutions like the TEXON and the specially developed covering

material Skintec, Bimos demonstrates how modern cleanroom

seating systems can meet these requirements: through consistent

Hygienic Design, tested material durability, high ergonomic

quality, and technical design for sensitive production environments.

Conclusion

Cleanroom-compatible seating systems provide much more than

ergonomic support. They contribute to cleanability, particle control,

ESD safety, and long-term process stability — and should therefore

be understood as a functional component of the entire cleanroom

concept.

Those who want to future-proof cleanroom workstations should

not see the work chair as a marginal component but as a core part of

a holistically planned, standards-oriented workstation system.

Bimos - eine Marke der Interstuhl Büromöbel GmbH & Co. KG

Brühlstraße 21

Telefon: +49 7436 8710

Telefax: +49 7436 871110

eMail: bimos@bimos.com

D 72469 Meßstetten-Tieringen

Internet: http://www.bimos.com

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 19/73


Moqlero - Automated Trending according to GMP Annex 1

Trends at the push of a button?

Why now is the right time to rethink

Trending in GMP Annex 1 – From „Nice-to-have“

to Regulatory Requirement

With the revision of EU GMP Annex 1 in 2022, the regulatory environment

for the manufacturing of sterile medicines has fundamentally

changed. A central element of this revision is the mandatory

introduction of systematic trending of monitoring data.

What was once considered a supportive quality tool is now an

integral part of compliance – and thus comes into focus for quality

assurance, production, and inspections alike.

From Reacting to Proactive Thinking

Trending describes the systematic, temporal analysis of monitoring

data to identify patterns, changes, and potential risks early on. Unlike

isolated consideration of individual limit breaches, developments

over longer periods become visible. The regulatory requirement is

clear: companies should no longer just react to deviations, but proactively

identify and prevent process deteriorations.

Annex 1 makes Trending Mandatory

In the revised Annex 1, especially in Chapter 9 („Environmental and

Process Monitoring“), trending is explicitly required and thus becomes

a mandatory component of environmental monitoring and the

Contamination Control Strategy (CCS).

A systematic evaluation of monitoring data is required to detect

trends, insidious changes, and recurring patterns early and to incorporate

them into the quality strategy.

This makes it clear: trending is no longer an optional reporting

tool, but a central control instrument to ensure product quality and

patient safety.

Requirements for Effective Trending

The Annex 1 sets clear expectations for implementation:

– Detection of trend patterns

Increasing limit breaches, recurring deviations, or consecutive

warning messages must be systematically recognized and

evaluated.

– Short- and long-term analysis

Both short-term events and long-term developments

are to be analyzed.

– Correlation with root cause analysis

Trending must be correlated with influencing factors such as

maintenance, personnel movements, or process changes and

forms the basis for root cause analysis and CAPA processes.

– Visualization and data preparation

Only through appropriate representations such as diagrams,

dashboards, and statistical evaluations do trends become

understandable and assessable.

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 20/73


When Excel Reaches Its Limits

In practice, a clear tension emerges between regulatory demands

and real-world application, as monitoring data are still often exported,

consolidated in Excel, and manually evaluated – an approach

that increasingly reaches its limits under today‘s requirements due

to high time consumption, lack of standardization, increased susceptibility

to errors, and limited traceability.

Automation as a Logical Consequence

Automated systems address exactly this point: they enable continuous

processing of data – from collection to analysis to structured

presentation of results. Trends can be analyzed regularly, patterns recognized

early, and evaluations standardized. Results are automatically

presented both graphically and in tables, making developments

immediately traceable.

Trending at the push of a button is less about simplifying and

more about a well-defined process. After setting the parameters,

evaluations can be retrieved in Moqlero with minimal effort. For

many in practice, this means a clear break from time-consuming,

error-prone Excel processes: instead of spending hours on manual

data preparation, reliable results are available in seconds – standardized,

audit-proof, and accessible at any time.

A Look into Practice

What sounds complex in theory has long become reality in practice.

Moqlero demonstrates impressively what Industry 4.0 cleanroom

monitoring can look like.

Whether particle concentration, filter test, or air exchange rate

– the platform initially automates mobile measurements of all kinds.

And this opens up new possibilities: since all measurement results

are available digitally natively, the new GMP Annex 1 trending requirements

can be seamlessly fulfilled. Trend reports with graphics,

tables, comments, and electronic signatures are generated without

media discontinuities, with just a few clicks.

Moqlero offers six different types of trends:

– Filter efficiency, for evaluating long-term filtration performance

– Filter differential pressure, for early detection of clogging trends

– Particle counts, for identifying contamination developments

– Physical environmental parameters such as temperature and

humidity

– Air volume flow, to ensure stable ventilation conditions

– Air change rate, for further verification of cleanroom compliance

Between Obligation and Opportunity

The requirements of Annex 1 may seem demanding at first glance

– but they offer the chance to fundamentally improve quality processes.

Consistent trending increases process stability, improves data

quality, and reduces deviations and risks in the long term. Those still

relying on manual processes risk not only compliance gaps but also

valuable time that could be spent on what truly matters: quality and

patient safety.

Getting started doesn‘t have to be difficult:

With Moqlero, automated trending can be set up quickly and is

ready for immediate use – new insights, no upfront investments, and

full compliance.

Conclusion

With the new EU GMP Annex 1, trending is finally moving from an

optional tool to a regulatory obligation. At the same time, this development

marks a fundamental change in the quality understanding

of the pharmaceutical industry. The future no longer lies in retrospective

data analysis, but in its digital, intelligent utilization.

Automated trending with Moqlero exemplifies a modern, integrated

quality approach that meets the increasing demands for transparency,

data integrity, and patient safety.

For pharmaceutical companies, the question is no longer whether

this approach will be implemented, but how quickly a sustainable

and future-proof implementation can be achieved.

MKL Ingenieurgesellschaft mbH

D 81827 München

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 21/73


GEA opens new technology center,

strengthening its position in the

growing pharma applications market

Together with Mona Neubaur, Minister of Economic Affairs

of the German state of North Rhine-Westphalia, GEA CEO

Stefan Klebert has opened a new technology center for pharmaceutical

freeze-drying systems in Elsdorf, Germany. GEA

employs approximately 260 people at the facility, which

combines research and development with production and

service under one roof. The site is carbon-neutral thanks to

power supplied by photovoltaic systems. The investment of

more than EUR 80 million underscores GEA’s commitment

to strengthening its position as a technology partner for the

growing global pharmaceutical industry. At the same time,

the company is making a positive contribution to structural

change in Germany’s Rhineland lignite mining region.

At the opening ceremony, GEA CEO Stefan Klebert said: “With our

new technology center in Elsdorf, we are investing in one of our key

growth areas and further strengthening our innovative capabilities

in the pharmaceutical sector. We are also significantly expanding

our production capacities. Together, these measures help us expand

our leading position in this highly innovative market segment.”

Mona Neubaur, Deputy Minister President and Minister of Economic

Affairs of the German state of North Rhine-Westphalia, was

a guest at the opening. “Today is a good day for the future of Elsdorf

and the entire region. From the heart of North Rhine-Westphalia,

GEA Group is driving the global transformation towards climateneutral

production. Efficient, digitally networked production methods

and sustainable technologies are helping to drive the transition

toward a resilient and climate-neutral economy. Elsdorf demonstrates

that North Rhine-Westphalia offers reliable framework conditions

to enable investments with significant impact. This way, we secure

good jobs, industrial value creation, and competitiveness, even

in challenging times.”

Digital on the inside, green on the outside

GEA opened a new pharmaceutical technology center

in Elsdorf (North Rhine-Westphalia). (Photo: GEA)

The new building in Elsdorf replaces an existing GEA freeze-drying

plant in neighboring Hürth, where production capacities had

reached their limits. The more than 260 employees will find ideal

conditions for their work in development, design, manufacturing,

assembly, and service at the new location. Production capacities can

be expanded, particularly through shorter production times.

Photovoltaic systems and green roofs on the production facilities

and office buildings will ensure carbon-neutral operation. GEA

uses the electricity from the roof to operate air-to-water heat pumps

for freeze-drying, heating and cooling at the site. This can save up

to 7,000 metric tons of CO₂ annually in production. Moreover, the

photovoltaic system powers 30 charging stations for e-cars and fleet

vehicles as well as six stations for e-bikes. As much of the approximately

45,000 square meter site as possible remained unsealed

thanks to the use of grass pavers.

A leader in pharmaceutical freeze-drying

Opening of the new GEA Pharma Technology Center in Elsdorf:

Johannes Giloth (COO, GEA), Michael Asenkerschbaumer (Managing

Director Lyophilization), Andreas Heller (Mayor of Elsdorf), Prof. Dieter

Kempf (Chairman of the Supervisory Board, GEA), Mona Neubaur

(Minister of Economic Affairs of North Rhine-Westphalia) and GEA

CEO Stefan Klebert (front row, from left to right). (Photo: GEA)

Freeze-drying is a necessary production step for many temperaturesensitive

medicines to extend their shelf life or make them transportable

in the first place. Alongside vaccines, these include antibiotics,

serums, diagnostic agents, protein-based and biotechnological

products, cells, tissues and chemicals. Production must meet

the pharmaceutical industry’s exceptionally high quality and safety

standards. Many of the corresponding manufacturing processes are

traditionally energy-intensive. GEA significantly reduces this energy

requirement through its innovative systems and processes. The

company has been systematically expanding its capacities and capabilities

in this growth market for years.

GEA Group Aktiengesellschaft

D 40468 Düsseldorf

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 22/73


www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 23/73


For example, the topic of explainability of AI using heatmaps

can contribute to regulatory-compliant development.

© Fraunhofer IPA/Photo: Rainer Bez

Particularly, robotics in use without safety fences requires

special safety measures. © Fraunhofer IPA / Photo: Rainer Bez

Bringing AI legally compliant into

practice: Reallabor KIRR Real develops

exemplary AI and robotics solutions

The goal of »KIRR Real: Living Laboratory for Legally Compliant

AI and Robotics« of the Fraunhofer IPA and ARE-

NA2036 was to support companies in Baden-Württemberg

in implementing the EU AI Act as well as the EU Machinery

Regulation coming into force in 2027. The results of the collaboration

with 15 companies are now published and serve

as guidance for companies with similar applications to develop

AI and robotic systems in a legally compliant manner.

Time is of the essence when it comes to current regulations: On August

2, 2027, the obligations for high-risk AI systems as safety components

will come into effect, and the entire EU AI Act will apply.

The new EU Machinery Regulation also sets new requirements for

safety-related AI and self-learning systems starting in January 2027.

Regulatory and technical consulting for companies

KIRR Real helped companies understand and implement these

complex regulatory requirements. For this purpose, »Legal Quick

Checks« were offered, which are short, concise consulting projects.

A law firm classified these cases into one of the four risk classes of

the AI Act (from minimal to unacceptable risk). Subsequently, the

Fraunhofer Institute for Production Technology and Automation

IPA examined the technical documentation and underlying concepts

of the AI development to evaluate the legal compliance of the

systems and to develop practical recommendations.

The project ran from November 15, 2024, to December 31, 2025,

and was funded by the Ministry of Economics, Labour and Tourism

of Baden-Württemberg. The consortium consisted of Fraunhofer

IPA and the research campus ARENA2036, supported by several associated

partners. The main objectives of the project were to investigate

how well companies in Baden-Württemberg are prepared for

the AI Act and the Machinery Regulation, how the two regulations

interact and overlap, and where there are still hurdles in AI regulation.

The insights gained from the project provide impulses for practical

implementation and further development of AI regulation and

are actively fed back into the legislative process, for example through

participation in standardization committees, regular exchanges with

the Federal Network Agency, the Federal Institute for Occupational

Safety and Health, and a workshop with the Federal Ministry of Labour

and Social Affairs. The project results are also intended to influence

the design of the living labs provided for in the AI Act.

Raising awareness of regulatory requirements

During the project, 15 AI application cases from areas such as manufacturing,

humanoid robotics, healthcare, and personnel management

were addressed. Even companies with advanced AI development

still needed support in implementing the AI Act. Discussions

also revealed that awareness of upcoming regulations is often insuf-

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 24/73


ficient. In applying the AI Act, either the legal or the technical aspect

was frequently considered, but both aspects and early engagement

with AI regulation are crucial for successful application.

Challenges in implementing the regulations

Particularly challenging for companies is the classification into risk

categories. This classification is crucial for resource planning but can

sometimes be ambiguous and depends heavily on the details of the

application case. Therefore, guidance based on similar cases is not

always possible.

The lack of harmonized standards means that more AI systems

must undergo conformity assessment by third parties. Regarding the

Machinery Regulation, many experts also see a need for clarification

on what exactly constitutes a system with »self-developing behavior«.

Another issue is the technical implementation of the requirements.

Many companies ask questions such as: How must evidence

be provided? How extensive must documentation be? When is AI

considered part of a machine? Handling multiple applicable regulations

is often unclear and causes fear of unnecessary additional

effort. Furthermore, many companies do not develop AI systems

entirely in-house but use existing general-purpose AI models for

their applications, which complicates the provision of the required

evidence. However, the available guidelines and support tools have

so far hardly addressed this practice.

An additional challenge for integrating AI into robots and other

machines is posed by the new Machinery Regulation: companies

must not only comply with the new rules for AI in safety functions

over the next twelve months but also adapt their existing products

to the new regulation.

Recommendations from the Living Laboratory

The experiences from KIRR Real show that while some companies

are engaging with the regulations, existing uncertainties, the multitude

of regulations to consider, and the lack of harmonized standards

pose significant problems.

There is an urgent need for concrete, practical, and easily implementable

guidelines, as well as structured approaches that start early

in development. Particularly, AI development teams—regardless of

company size—are often small and struggle to manage the required

efforts. Support offers (such as living laboratories) should therefore

be as accessible as possible to provide real added value. Companies

should also receive support early in development, for example

through legal assessments of an application case, workshops, or consulting

during system development.

The Fraunhofer IPA will continue to collect insights from the

project work and actively contribute to the legislative process, as well

as use these insights for direct collaboration with companies. Companies

can contact our representatives for this purpose. The goal remains

to further develop AI regulation in a practical manner and to

support companies in Baden-Württemberg optimally.

Fraunhofer-Institut für Produktionstechnik und Automatisierung IPA

Nobelstraße 12

D 70569 Stuttgart

Telefon: +49 711 970 1667

eMail: joerg-dieter.walz@ipa.fraunhofer.de

Internet: http://www.ipa.fraunhofer.de

NEWSLETTER | Ausgabe EN 05-2026

Seite 25/73


(Image credits: © nora)

(Image credits: © nora)

Noravant Timber Rubber Floors for Modern Laboratory and Cleanroom Architecture

When function creates atmosphere

Experts in laboratory technology and the planning of safety-related

facilities know: laboratories and cleanrooms are highly functional

work environments with clearly defined requirements. In recent

years, these requirements have continued to increase in an increasingly

complex environment. In addition to integrating innovative

technologies, adhering to strict safety standards, and optimizing

efficiency and resource utilization, aspects such as comfort, design,

and sustainability are now also coming into sharper focus. Atmosphere

and well-being are gaining importance – even in areas that

were long considered purely functional. This is precisely where the

new rubber flooring noravant timber comes into play. It combines

the appearance of natural wood design with the performance that

is indispensable in laboratories and cleanrooms. The sheet flooring

opens up new creative possibilities for areas where safety and design

go hand in hand.

between design and function is essential,“ says Bettina Haffelder,

Vice President DACH nora. „With noravant timber, it has

been possible to develop a flooring with an authentic wood look

that is easy to clean and characterized by outstanding resistance

to media.“

Durability for demanding applications

As important as aesthetics are – in laboratories and cleanrooms,

performance ultimately decides. The innovative surface technology

ensures an exceptionally high resistance against a wide range of laboratory

chemicals. This reduces cleaning effort and simultaneously

helps maintain the quality of the rooms in the long term – for a permanently

pleasant working environment and sustainable preservation

of the laboratory property.

Design as a functional added value

Colors, materials, and surfaces influence motivation, concentration,

and ultimately the quality of work results. The floor is

an integral part of modern laboratory architecture and plays an

important role within a comprehensive concept that considers

both function and design equally. The calm oak look of noravant

timber and its matte surface create a surface that intentionally

recedes and yet produces a pleasant room atmosphere. „Especially

in laboratory and cleanroom areas, the close connection

nora systems GmbH

Höhnerweg 2-4

D 69469 Weinheim

Telefon: +49 6201 2743934

Mobilfunk: +49 172 6330484

eMail: frank.baehr@nora.com

Internet: http://www.nora.com

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 26/73


Invisible particles,

real consequences:

New Camfil film

shows why clean

indoor air protects

health

How clean is the air we breathe indoors, and what impact does it

have on our health? A film recently released by filter manufacturer

Camfil addresses these questions as part of the international series

„Healthier Together.“ Healthier Together is a series by the WHO

Foundation and was produced by BBC StoryWorks Commercial

Productions.

Whether cooking, heating, cleaning, or simply normal building

use: microscopic particles are generated in everyday life. In modern,

energy-efficient buildings, these particles remain in the air for a long

time if ventilation and filtration are inadequate – with consequences

for the well-being and health of the people inside the building.

„At Camfil, we work with something that cannot be seen, but

whose effects everyone can feel: air. Understanding and actively

controlling indoor air quality reduces risks, protects people, and

creates a noticeably better environment,“ says Anders Sundvik, VP

Product & Innovation at Camfil, who introduces the topic in the film.

Those responsible for schools, offices, and other public buildings

should not consider providing clean air merely as a technical issue,

but as an essential part of responsible building planning and management.

The film is available on the Camfil website. There, additional information

is provided on simple measures for better air quality at the

workplace.

About the series „Healthier Together“

Healthier Together is a video series created in collaboration with the

WHO Foundation. It was produced by BBC StoryWorks Commercial

Productions on behalf of participating organizations. The series

highlights global health challenges and opportunities – in cities and

villages, in hospitals and at home – and shows how people work together

to achieve the goal of health for all.

Camfil GmbH

Feldstr. 26 - 32

D 23858 Reinfeld

Telefon: +49 4533 2020

Telefax: +49 4533 202202

eMail: info.de@camfil.com

Internet: http://www.camfil.com

NEWSLETTER | Ausgabe EN 05-2026

Seite 27/73


Hermann Bantleon GmbH and IQM Oberflächentechnik GmbH

implement sustainable solutions for clean components

Holistic process optimization

in surface technology

Clean components are a central quality factor

in industrial manufacturing. Together

with IQM Surface Technology GmbH, Hermann

Bantleon GmbH has demonstrated

how demanding requirements in surface

technology can be efficiently and sustainably

implemented through a holistic view of

the entire process chain. From processing to

component cleaning to secure VCI packaging.

Goods carriers and components ready for

cleaning with Bantleon cleaning media.

(Copyright: Hermann Bantleon GmbH)

The starting point was the commissioning

of a new cleaning system at IQM. The challenge

was to find a partner for a cleaning

medium that can be used for all alloys offered

by the company to its customers – while

maintaining consistently high cleaning performance.

„With the commissioning of a new system

in 2021, we faced the task of finding a

cleaning medium suitable for all alloys we

process. At the same time, we had to ensure

that we reliably meet the high quality standards

of our customers,“ explains Sebastian

Trakies, Commercial Manager of IQM Surface

Technology GmbH. „With Bantleon, we

found this partner and can clean all components

in our cleaning system as needed

to ensure the quality of our customers on a

long-term basis.“

The focus of the project was to reliably

achieve clean components while optimally

coordinating all process steps. After

vibratory polishing, specially tailored cleaning

media ensure the effective removal of

contaminants. The subsequent residual dirt

analysis in a cleanroom guarantees compliance

with the required quality standards. In

this way, permanently clean components

and high process security for subsequent

manufacturing steps are achieved.

A key success factor was the individual,

technical consulting provided by Bantleon

throughout the entire process. In addition

to selecting the appropriate cleaning medium,

Bantleon also supported IQM in designing

the suitable VCI packaging. This

reliably protects the cleaned components

from corrosion and prepares them safely for

storage and shipping. Cleaning, corrosion

protection, and packaging were considered

as an integrated overall system and precisely

tailored to IQM‘s requirements.

„We especially appreciate that Bantleon‘s

technical advisor is always available

and supports us directly,“ says Melanie

Rehm, Production Manager at IQM Surface

Technology GmbH.

The joint success story shows that successful

cleaning and high-quality surface

technology do not arise from individual

products, but through partnership collaboration,

technical expertise, and a consistent

focus on the entire process. This way, quality,

efficiency, and sustainability can be increased

simultaneously – an approach that

is increasingly gaining importance in modern

surface technology.

Hermann Bantleon GmbH

D 89077 Ulm

The cleaning media from Bantleon

ready for use.

(Copyright: Hermann Bantleon GmbH)

VCI packaging by Bantleon for safe storage and secure transportation.

-(Copyright: Hermann Bantleon GmbH)

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 28/73


Bild: AdobeStock_569552759

Synergies for high-tech

cleanroom planning

Lorenz Consult is now a partner in the Silicon Alps Cluster, an important technology

and innovation network for electronic and software-based systems in Austria.

As one of Austria‘s leading general planners for complex buildings, the company

is strengthening its network within the electronics and microelectronics industry.

The goal of the collaboration is to recognize technological trends early and integrate

them into the planning of highly specialized cleanroom infrastructures.

Focus on the Interface of Building and Process

The Silicon Alps Cluster brings together actors from industry, research, and the public

sector from southern Austria. For Lorenz Consult, this platform offers direct access

to the technological requirements of the future. Since cleanrooms in semiconductor

manufacturing or sensor technology are subject to extreme requirements for

particle-free environments, vibration isolation, and climate stability, close exchange

with system developers is essential.

„The partnership in the Silicon Alps Cluster provides us with a knowledge advantage.

We understand earlier how our customers‘ manufacturing technologies are

developing, and can precisely tailor the building infrastructure and building technology

accordingly,“ explains Christian Lorenz, Managing Director of Lorenz Consult.

Innovation and Sustainability in Cleanroom Technology

A central concern of the partnership is the consistent integration of technological

progress and sustainable building design. Especially in energy-intensive cleanroom

projects, resource and energy efficiency play a crucial role. Lorenz Consult uses the

network to further develop innovative planning approaches that meet the increasing

ecological and economic demands of the industry.

Strategic Added Value for High-Tech Industries

With this membership, Lorenz Consult consolidates its position as a specialized

partner for the electronics and microelectronics industry, as well as for pharmaceuticals,

laboratories/biosafety, and food. Customers benefit from planning that not only

meets current standards but also considers the technological cycles of the coming

years. The continuous transfer of process know-how from the cluster directly into

the planning phase ensures the future viability of demanding cleanroom and laboratory

projects.

Lorenz Consult Ziviltechniker GmbH

AT 8010 Graz

NEWSLETTER | Ausgabe EN 05-2026

Seite 29/73


Hannusch EMS Increases Line Flexibility

with ASYS Automation Solutions

Hannusch Industrieelektronik GmbH, based in Laichingen (Baden-

Württemberg, Germany), is an experienced EMS provider specializing

in demanding electronics manufacturing. To increase line flexibility

and optimize setup and throughput times, the company implemented

a new SMD production line equipped with automation and

software solutions from the ASYS Group. The collaboration between

Hannusch and ASYS has been ongoing since 2009 and was further

strengthened through this project.

Seamless Communication for Efficient Product Changeovers

The objective of the line concept was to economically manage up to

20 product changeovers per day without compromising equipment

availability or throughput. This required short setup times as well as

stable, standardized machine-to-machine communication across

the entire line.

The line is equipped with multiple ASYS modules for PCB handling,

including loading and unloading modules, transport systems,

buffer and magazine solutions, turning and singulation units, as well

as workstations and interface stations. The hardware is complemented

by the SynapticaOS Hermes Assistant as a central software solution

for product and line management.

The VEGO modules used automatically adapt to different PCB

formats and ensure a continuous material flow, even with frequent

product changes.

Scalable Architecture for Future Automation Steps

The Hermes standard and the associated software solutions are

continuously being further developed at ASYS. Currently, Hannusch

uses the Hermes Assistant for product data management and line

changeovers. Looking ahead, the changeover process is planned to

be further automated and executed directly at the machines. In addition,

cross-line communication is to be expanded in the future to

unlock further efficiency potential across the entire production environment.

“The collaboration was always very pleasant and on an equal

footing. Response times were fast, and the support was excellent.”

Michael Hannusch, CEO, Hannusch Industrieelektronik GmbH

Results and Added Value

– High line flexibility: Realization of up to 20 product

changeovers per day

– Standardized communication: Hermes protocol

as the foundation for scalability and future automation

– High equipment availability: Robust, low-maintenance ASYS

systems designed for continuous industrial operation

– Long-term partnership: Close, solution-oriented collaboration

with a focus on continuous process optimization

Successful Implementation of Standardized Interfaces

During the project, the integration of the Hermes standard posed

a technical challenge, as it is interpreted differently by various

equipment manufacturers. Through close coordination between

Hannusch, ASYS, and the involved machine suppliers, end-to-end

Hermes communication across the entire line was successfully implemented.

ASYS Prozess- und Reinraumtechnik GmbH

Lerchenbergstraße 31

D 89160 Dornstadt

Telefon: +49 7348 98560

eMail: cleanroom@asys-group.com

Internet: http://www.asys-group.com

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 30/73


Arnt König takes over the operational leadership of the German market

– Group aligns management capacities more internationally

Testo Industrial Services expands

management team for further growth

Testo Industrial Services (TIS), one of the leading full-service providers in the

fields of measurement technology, quality management, and calibration in Europe,

is expanding its management team: Arnt König is appointed as the second

operational managing director and simultaneously takes on the role of Deputy

Managing Director from Raimund Föhrenbacher. With this step, TIS strengthens

its management structure and creates additional capacities for further international

growth and increasing demands within the group.

Führen das Unternehmen gemeinsam in die Zukunft: Raimund Föhrenbacher (rechts)

und der neue Geschäftsführer Arnt König (links). © Testo Industrial Services GmbH

Broad experience for key future tasks

velopment of the Swiss market and has

advanced international cooperation within

the group. His deep understanding

of customer needs, markets, and internal

processes makes him an ideal candidate

for the operational leadership of the

group‘s largest TIS market.

„For me, this new role is a great honor

and the next exciting development step,“

says Arnt König. „I look forward to further

expanding our strong market position in

Germany and actively shaping the group‘s

international orientation.“

In his new role, König will not only assume

operational responsibility for Germany

but also central customer-oriented topics

such as Sales & Marketing International – a

Arnt König brings an exceptionally broad

background of experience to his new role,

which has connected him closely with the

development of Testo Industrial Services

for over twenty years. Since joining in 2003,

he has actively supported and significantly

shaped the company‘s key growth phases.

His operational expertise ranges from sales-related

key positions to long-standing

leadership roles in the German organization,

up to international responsibility as Managing

Director of Testo Industrial Services

Switzerland.

In this position, König has provided

important impulses for the strategic dekey

to linking local excellence with global

strategy.

Strengthening of international

orientation

With the expansion of the management

team, Testo Industrial Services is focusing

even more strongly on the group‘s international

development. TIS has grown dynamically

in recent years and now works much

more closely with the national subsidiaries

and the parent company Testo in Titisee.

This environment necessitates a clear division

of roles to manage the increasing demands

of internationalization, scalability,

and synergies in a structured and futureoriented

manner.

Raimund Föhrenbacher will increasingly

focus on the strategic management of the

entire TIS group – particularly on implementing

the Group Strategy 2030 and establishing

stronger international collaboration.

The goal is to further increase the global

performance of the organization while specifically

strengthening operational focus in

the German market.

„Our group is growing rapidly, and with

it, the demands on leadership and internationalization,“

says Raimund Föhrenbacher.

„With the new structure, we create more

space for strategic development – and at the

same time ensure the necessary attention

for our strongest market in Germany.“

The new division of roles creates a clear

and efficient structure that optimally supports

both the international orientation and

the local market dynamics.

Testo Industrial Services GmbH

Gewerbestraße 3

D 79199 Kirchzarten

Telefon: +49 7661 909018000

eMail: gmp@testotis.de

Internet: http://www.testotis.de

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 31/73


Green Elephant Biotech and

Bürkert Fluid Control Systems

present Archimedes® One for scalable

and automated adherent cell culture

Innovative partnership revolutionizes

cell therapy production

Green Elephant

Biotech presents

the dynamic adherent

bioreactor Archimedes®

One, a new platform

designed to simplify and

scale adherent cell culture

processes.

Green Elephant Biotech announced the introduction

of the Archimedes® One — Dynamic

Adherent Bioreactor, a new platform

designed to simplify and scale adherent cell

culture processes. The system was developed

in close collaboration with Bürkert

Fluid Control Systems, combining Green

Elephant Biotech’s cultivation technology

with Bürkert’s expertise in fluidic control

and automation. The collaboration between

the two companies began at analytica 2024,

when Bürkert’s application management

Joel Eichmann (left) and Felix Wollenhaupt (right) from Green Elephant Biotech, together with

Georg Stawowy (second from left) and Hendrik Faustmann (third from left) from Bürkert Fluid

Control Systems, proudly look back on their one-year partnership and their first joint product.

team discovered Green Elephant’s technology.

Recognizing the potential to jointly address

key challenges in biopharmaceutical

manufacturing, Bürkert subsequently joined

Green Elephant Biotech as a strategic investor,

establishing the foundation for a longterm

development partnership.

Together, the teams focused on integrating

advanced fluidic and automation technologies

with next-generation cell culture

systems. The result of this collaboration is

the Archimedes® One, the first system in a

new category designed specifically for scalable

adherent cell cultivation.

Adherent cell processes remain central

to many emerging cell and gene therapies

but are often difficult to scale. Traditional

two-dimensional culture systems rely on

manual workflows and large numbers of

vessels, while suspension systems frequently

require adapting sensitive cell types. Fixed-bed

bioreactors can provide scalability

but introduce significant hardware complexity

and operational overhead.

Archimedes® One takes a biology-first

approach. Instead of forcing adherent cells

into suspension or complex matrices, the

system enables controlled, perfusion-based

cultivation using the CellScrew® geometry,

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 32/73


providing a large growth surface within a

compact footprint. Automated media distribution

and integrated cell harvesting reduce

manual intervention and support reproducible,

standardized workflows.

Through the integration of Bürkert’s

fluidic control technologies, the system

enables precise control of media and gas

flows. In combination with a connected

biocontroller, key process parameters such

as pH, dissolved oxygen, and temperature

can be monitored and controlled, bringing

bioreactor-level process control to adherent

cell cultivation.

“Cell therapy manufacturing should not

require choosing between biological integrity

and industrial scalability,” said Joel

Eichmann, Co-Founder of Green Elephant

Biotech. “With Archimedes® One, we are

introducing a platform that aligns process

control with adherent cell biology while significantly

reducing operational complexity.”

“The collaboration with Green Elephant

demonstrates how precise fluidics and

automation technologies can open up new

possibilities in cell culture technology,” says

Hendrik Faustmann, Manager New Business

Model Development at Bürkert Fluid

Control Systems. “By combining our expertise

in automation and system integration

with Green Elephant’s cultivation platform,

we have created a system architecture that

seamlessly integrates fluid management

and process control—optimally tailored to

the requirements of modern adherent cell

processes.”

The system is currently being introduced

to the market ahead of its planned commercial

launch later this year. In parallel,

Green Elephant Biotech is opening an Early

Access Program for selected cell therapy

companies and CDMOs, providing early

access to production units, dedicated technical

support, and the opportunity to contribute

to application data and case studies

ahead of the commercial launch.

“The Early Access Program allows us

to work directly with therapy developers

and CDMOs as we prepare for commercial

launch,” said Felix Wollenhaupt, Co-Founder

at Green Elephant Biotech. “Together,

we want to demonstrate how Archimedes®

One integrates into real manufacturing

workflows and supports scalable adherent

cell production.”

Green Elephant Biotech and Bürkert

Fluid Control Systems will present the dynamic

adherent bioreactor together at analytica

2026 in Munich (Stand A1.419), where

visitors can learn more about the joint development

and experience the system firsthand.

Companies interested in the Early Access

Program can apply via:

www.greenelephantbiotech.com/eap

Bürkert GmbH & Co. KG

D 74653 Ingelfingen

BioCapt® Single-Use Microbial Air Sampler

for a Continuous Cleanroom Monitoring

Learn more

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe DE 05-2023 Seite 33/103


© Fraunhofer IPA/Foto Rainer Bez

»Humanoid Capabilities Navigator«:

What technical skills does a humanoid

robot possess?

A research team from Fraunhofer HNFIZ has published

a newly developed evaluation model that categorizes the

technical capabilities of humanoids across five levels of development.

Applications can also be classified based on the

robot capabilities required. The model makes humanoids

comparable, facilitates the selection of the right humanoid

for a specific application, and highlights open topics in

technology development.

Against the backdrop of increasing skilled labor shortages and rapid

advances in artificial intelligence (AI) and robotics, humanoid robots

are becoming increasingly prominent in industry and logistics.

Companies face the central question of when and for which tasks

humanoid robots are technically and economically viable or will

become so. Many companies and research institutions are already

testing initial systems, but until now, there has been a lack of a comprehensive,

comparable evaluation model.

Transparency and comparability for humanoid robots

This is where the Humanoid Capabilities Navigator, developed by

the Fraunhofer Institute for Production Technology and Automation

IPA at the Heilbronn site, comes into play. It has been published in a

newly released white paper. Fraunhofer IPA, as part of the research

and innovation center for AI-based robotics, is a component of the

Fraunhofer Heilbronn Research and Innovation Centers HNFIZ and

works on topics such as intelligent mobile manipulation and flexible

use of robotic arms, as well as humanoids.

The Humanoid Capabilities Navigator is broadly inspired by the

five levels of automation in autonomous driving and evaluates humanoid

robots based on four categories, which often include various

technical capabilities and their levels of development:

– Mobility and locomotion (including localization

and path planning)

– Manipulation (including force perception and grasp planning)

– Cognition (including perception and task planning)

– Safety and security

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 34/73


For each capability within a category, humanoids can be classified

according to maturity levels from 0 (not present) to 4 (highly autonomous,

comparable to or better than humans). This allows for the first

time a transparent, manufacturer-independent, and well-founded

comparison of different humanoids and provides information about

their suitability for specific applications.

Practical assessment of real-world applications and robots

The publication illustrates the use of the Humanoid Capabilities

Navigator in typical industrial applications such as truck loading

and unloading, order picking, machine operation, and maintenance

tasks. For each task, the necessary technical maturity levels in

the four capability areas are outlined. For example, truck loading

demands the highest levels in manipulation, cognition, and safety,

while machine operation requires lower levels due to the more structured

process, which involves less flexibility in task execution.

Using a current humanoid robot, the G1 from Unitree Robotics,

the automation division of Fraunhofer IPA tested the Humanoid Capabilities

Navigator. It was found that the current G1 version has already

made significant progress in areas such as mobility. However,

there is still considerable development needed to fully meet industrial

requirements. The evaluation model makes these gaps transparent

and helps to specifically prioritize development efforts.

Guidance for research, development, and market forecasts

The Humanoid Capabilities Navigator provides industry with a practical

tool to realistically assess the potential of humanoid robots,

validate investment decisions, and derive targeted research and development

measures. It also enables a reliable assessment of future

market developments, as the progress of the technology is systematically

linked to specific application requirements.

This white paper is part of several publications that the institute

has already published or will publish in the first half of 2026.

All of them focus on providing companies with comprehensive

and reliable material to evaluate and assess the economic and

technical feasibility of deploying humanoid robots for their own

applications.

Fraunhofer-Institut für Produktionstechnik und Automatisierung IPA

Nobelstraße 12

D 70569 Stuttgart

Telefon: +49 711 970 1667

eMail: joerg-dieter.walz@ipa.fraunhofer.de

Internet: http://www.ipa.fraunhofer.de

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe DE 05-2023 Seite 35/103


A-look-inside-imec‘s-300mm-cleanroom. (Photo: Imec)

Semiconductor-based

Quantum Pilot Line ‘SPINS’

launched with EU support

IMEC-SPINS. (Photo: Imec)

On April 2, 2026, SPINS (Semiconductor

Pilot line for Industrial Quantum NanoSystems)

was inaugurated, one of six European

quantum pilot lines. The consortium coordinated

by imec brings together 25 European

research institutions, industry partners, and

academic research groups to strengthen

Europe‘s leadership and sovereignty in this

strategically important field. The €50 million

SPINS pilot project is made possible

through co-financing from the European

Union‘s „Chips Joint Undertaking“ (Chips

JU) as well as national and regional authorities

of the participating member states.

Quantum computing has developed

into a highly strategic area with rapidly increasing

economic and societal importance.

Applications range from breakthroughs in

drug research and materials science to extremely

secure communication and nextgeneration

navigation systems.

However, there is still a gap between

current quantum research and the manufacturing

of quantum processors that enable

significant quantum applications. Scaling

the number of stable qubits (up to one billion)

is the key to building reliable and faulttolerant

quantum computers.

Considering the technological complexity,

which includes cryogenic operation,

high-precision control electronics, and

highly specialized manufacturing processes,

and given the strategic importance of quantum

chips, six complementary quantum

pilot lines have been established under the

EU-Chip Act. Each focuses on a specific

hardware platform and collectively advance

quantum technologies in the areas of quantum

computers, communication, and sensing.

Within this portfolio, SPINS is the pilot

line dedicated to semiconductor-based spin

qubits, with a primary focus on developing

quantum chips for quantum computer applications.

Imec coordinates this new pilot

line and leads a European consortium of 25

partners from research institutions such as

Fraunhofer, VTT, and CEA-Leti, from industry

(including large companies like Infineon

and Siltronic as well as SMEs and startups),

and from academic groups (such as TU Delft

and the University of Jyväskylä), who share

their knowledge and skills with the goal of

translating the strategic framework of the

EU-Chip Act into concrete actions.

Initial projects of the SPINS consortium

include process and design optimization

to create a robust foundation for scalable,

stable, and high-performance spin qubits

on three different technology platforms:

Si/SiGe, Ge/GeSi, and SOI. SPINS aims

to transfer this technology from the lab

into production via Multi-Project Wafers

(MPW) and standardized quantum Process

Design Kits (PDKs), lowering entry barriers

for startups and SMEs in semiconductor

quantum technology and laying the groundwork

for European companies to build early

quantum expertise.

Quote from imec - Kristiaan De Greve,

SPINS Coordinator: „Scaling qubits requires

an extremely controllable environment and

solid manufacturing processes due to the

extreme sensitivity of qubits to environmental

disturbances. These challenges demand

the precision and control only available in a

semiconductor cleanroom infrastructure, as

well as the research and innovation mindset

to adapt such environments to these sensitive

qubits. At imec, we have been creatively

tackling complex problems in modern semiconductor

manufacturing for over 40 years.

By pooling the expertise of our European

consortium partners in this quantum pilot

line, we will accelerate the development of

high-TRL semiconductor qubits and enable

quantum systems at a larger scale, made in

Europe.“

In addition to the semiconductor technology

pilot line, there are other European

quantum research projects, including the

photonics pilot line for quantum „P4Q“ (coordinated

by the University of Twente, NL),

in which imec is also involved; ion trap qubits

„CHAMP-ION“ (coordinated by SAL,

AT); superconducting qubits „SUPREME“

(coordinated by VTT, FI); diamond quantum

chips „DIREQT“ (coordinated by CNR, IT);

and neutral atoms „Q PLANET“ (coordinated

by Pasqal, FR).

IMEC Belgium

BL 3001 Leuven

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 36/73


Production sites in Europe and the USA increase process efficiency and capacities

Vetter continues to expand his global

network for clinical manufacturing

– Construction measures at the new clinical site in Des Plaines

are proceeding on schedule

– Expansion of infrastructure at the Austrian site

strengthens clinical processes

– Established site in Skokie continues to show positive results

Vetter, one of the world‘s leading pharmaceutical

service providers in the field of

aseptic production of injectable medicines,

announces the further expansion of its global

network for clinical manufacturing. With

the continuous extension of its service offerings

in Vetter Development Service, the

company is taking decisive steps to provide

the necessary capacity, state-of-the-art

technologies, and specialized expertise to

meet the increasing worldwide demand. By

further strengthening its presence in Europe

and the USA, Vetter positions itself as a

reliable, long-term partner for biopharmaceutical

innovators worldwide.

“Our ongoing global expansion reflects

our holistic approach to comprehensively

support our customers in their clinical development,”

says Dr. Claus Feußner, Senior

Vice President of Vetter Development Service.

“Through investments in technology

and capacity, we provide our partners with

tailored manufacturing services for early development

phases, ensuring their molecules

successfully progress from the laboratory to

the clinic.”

US locations with strong performance

and major expansion projects

Vetter continues to grow in the USA. The

site in Skokie, Illinois, remains a key partner

for global biotech companies. Since its opening,

the site has supported over 140 customers

and more than 350 active substances

on the demanding path through clinical development.

Over 40% of Skokie’s customers

are startups or small companies with fewer

than 50 employees.

Building on this foundation, construction

of the new 15,000-square-meter facility

in Des Plaines, Illinois, is progressing on

schedule. With the steel structure expected

to be completed soon, interior work will begin.

After commissioning in 2029, the site

will further increase Vetter’s clinical production

capacities in the USA and strengthen

the company‘s long-term commitment.

The construction work at the Vetter

construction site in Des Plaines is

progressing as scheduled (April 2026).

©Vetter Pharma International GmbH

European site grows in response

to customer demand

Vetter’s European manufacturing facility in

Rankweil, Austria, is also developing very

positively in the production and quality

control of drug candidates for clinical trials.

To meet the steadily increasing project volume,

Vetter is implementing several infrastructural

adjustments at the site.

The measures include establishing an

additional weighing room and another formulation

area within the aseptic production

zone. Capacity for manual optical inspection

is also being increased. Additionally,

the service offerings at the site will benefit

from new cooling rooms, specialized freezing

units for API storage, and another incubation

chamber for microbiological testing.

Through continued process optimization

and capacity expansion on both sides

of the Atlantic, Vetter is strengthening its

role as a global partner for comprehensive

and cGMP-compliant clinical development

and aseptic manufacturing. Close coordination

between the European and US sites

ensures harmonized processes, consistent

quality standards, and the flexibility needed

to meet the evolving requirements of customers

worldwide.

Vetter Pharma International GmbH

D 88212 Ravensburg

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 37/73


BASF and Schütz have signed a settlement agreement

for the construction of a highly automated production and

storage facility for Intermediate Bulk Containers (IBC) at BASF‘s

headquarters in Ludwigshafen. (Photo: Schütz)

Schütz invests in a state-of-the-art

IBC production facility at BASF’s

main plant in Ludwigshafen

– Construction of a highly automated production and storage

facility for intermediate bulk containers (IBC)

– Close proximity enables maximum delivery flexibility, short

transport routes and 24/7 just-in-time delivery

– Schütz’s investment underscores the strategic partnership

between the two companies

BASF and Schütz have signed an agreement

for the construction of a highly automated

production and storage facility for intermediate

bulk containers (IBCs) at the BASF

headquarters in Ludwigshafen. The new

IBC production facility will ensure the secure,

long-term supply of industrial packaging

to the BASF plant. Work on building the IBC

production facility is scheduled to commence

in the third quarter of 2026.

A supply concept firmly focused

on the future

Schütz has teamed up with BASF to develop

a new, comprehensive concept for the supply

of industrial packaging to the site, in the

course of which Schütz’s future production

facility and the chemical site will be closely

interlinked in terms of infrastructure and

logistics. A core component is the construc-

tion of a state-of-the-art IBC manufacturing

plant on a site directly adjacent to the

chemical company’s factory perimeter. The

concept also includes an advanced, digitalised

packaging warehouse that will be integrated

in the container production facility,

and the continued roll-out of the reuse, reconditioning

and recycling of used packaging

containers. “This project is not only a

bold signal for sustainable site development;

it also stands for highly-efficient, customerspecific

on-site solutions and the further

expansion of our role as a strategic partner

to the industrial sector”, says Roland Strassburger,

CEO of the Schütz Group.

“The targeted attraction of long-standing

partners and the investment in production

capacities close to the site create

decisive structural advantages for our main

plant”, says Helmut Winterling, President

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 38/73


creates maximum supply security for our

operations. The proximity and integration

keep transport routes short and allow us to

respond flexibly at all times to changing demands

in our production plants and facilities”,

says Uwe Lohr, Senior Vice President

Global Indirect Procurement, BASF SE.

A partnership spanning decades

provides a solid foundation

Schütz has developed a new, comprehensive supply concept with industrial packaging

for the Ludwigshafen site in collaboration with BASF. A core component is the establishment

of a state-of-the-art plant for IBC manufacturing on a site owned by the chemical company,

located in close proximity to the Verbund site. (Photo: Schütz)

European Verbund Sites, BASF SE. “The

integration of IBC manufacturing into our

material and production cycles strengthens

our competitiveness in the long term.”

“Schütz’s new site close to our facility

The collaboration between BASF and

Schütz dates back to the 1960s. A milestone

was the development of the world’s first IBC

in 1975 by Udo Schütz in close cooperation

with BASF – an innovation that fast became

the standard for industrial packaging

worldwide. At the BASF site in Ludwigshafen,

the classic intermediate bulk container

is used, among other things, for the storage

and transport of chemical products in liquid

form; these typically include chemical

bases such as dispersions, additives and

surfactants. Today, Schütz operates a global

production network with more than 70 locations

and supplies BASF sites worldwide as

well as numerous other customers across a

wide range of industries.

SCHÜTZ GmbH & Co. KGaA

D 56242 Selters

Clean Room Design

Glatt Process & Plant Engineering

Pharma+Biotech provides a

holistic planning that brings

together all interfaces and

engineering disciplines in

advance.

Cleanrooms as an integral part of

complex system planning.

Let‘s develop your

optimum solution.

ppe.glatt.com

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe DE 05-2023 Seite 39/103


Analytik Jena celebrates

40 years of Biometra

– a success story in

molecular biology

Analytik Jena, together with its subsidiary Biometra, looks

back on four decades of technological excellence in molecular

biology. Since its founding in 1985, Biometra has significantly

influenced laboratory practices – from early electrophoresis

systems to pioneering PCR thermocyclers and

modern platforms for automated, precise workflows. This

success story is closely linked to customer proximity, engineering

craftsmanship, and a clear quality standard.

In the early years, Biometra relied on precision and reliability: the

first products enabled efficient separation and analysis of DNA,

RNA, and proteins. They quickly became standard in many laboratories.

The introduction of early PCR thermocyclers in 1989 marked

a turning point: DNA amplification became faster, more precise, and

user-friendly. In the 1990s, Biometra established its role as a trusted

technology partner in research and diagnostics worldwide.

In the 2000s, Biometra strategically expanded its portfolio:

solutions for DNA/RNA extraction and quantitative PCR (qPCR)

were added to meet the growing demands of modern laboratories.

A milestone in the company‘s history followed on May 11, 2009:

Biometra became part of the Analytik Jena Group. This connection

strengthened the joint product offering – from thermocyclers to

electrophoresis and blotting to imaging and hybridization technologies

– and opened new markets as well as synergies in development

and service.

The impact on science and society is well documented: with

the TGradient thermocycler, Biometra contributed to decoding the

human genome, a milestone in modern biology. During the CO-

VID-19 pandemic, the central importance of (q)PCR systems was

reaffirmed: Biometra technologies supported molecular diagnostics

worldwide at a high level. Strategic collaborations – for example with

Max Planck institutions in protein purification – further promoted

knowledge exchange and accelerated innovations that resulted in

practical solutions.

Since the 2020s, Biometra has increasingly focused on energy

efficiency, sustainability, and integration into automated laboratory

environments – always with the goal of making precise results available

faster and more robustly.

“Our vision is to shape the next 40 years as boldly and consistently

as the past ones,” says Eggert Appel, Head of Product Development

at Biometra. “Technologically mature products, high userfriendliness,

and seamless integration into automated processes

remain central guiding principles of our work.”

Oliver Klaeffling, Managing Director of Analytik Jena GmbH +

Co. KG, thanks all employees, partners, and customers who have

accompanied Biometra over four decades. “Your commitment and

trust are the foundation of our success – and an incentive for the

future.”

Analytik Jena GmbH+Co. KG

D 07745 Jena

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 40/73


Dr.-Ing. Carlos Paiz Gaitca, Business Owner Industrial Analytics (left)

and Ralph Scheller, Team Leader of Software Development

at ResMa (right), accept the award. Image source: Weidmüller

ResMa® monitors the values from numerous

measurement stations and offers visualization options.

Image source: Weidmüller

Award for Energy Management

and Regression Analysis

The resource and energy management system ResMa® from Weidmüller

has been awarded the Product of the Year by Industrial Production.

The system achieved third place in the category „Energy

Technology and Electromechanics.“ The award „recognizes outstanding

industrial products and projects,“ according to the self-description.

ResMa® steps onto the winners‘ podium. At the official award

ceremony of Industrial Production in Munich, the energy management

system was chosen for third place in the category „Energy

Technology and Electromechanics.“

The approach of ResMa® was recognized for not only transparently

evaluating energy consumption using regression and

correlation analyses but also reliably predicting it. By normalizing

historical and current data, savings can be objectively assessed

and future consumption realistically forecasted — independent of

external influences such as temperature or working hours. „The

award is a great honor and shows that our products meet the

needs of our customers and the requirements for more efficient

energy use,“ reports Dr.-Ing. Carlos Paiz Gatica, Product Owner

for Industrial Analytics.

The jury for the award consists of the readers. In an open online

voting, they can vote for their favorites. Ralph Scheller, Team Leader

of Software Development for ResMa®, is also excited: „I am pleased

with the great appreciation from the readers. A special thanks goes

to the team that has worked long and intensively on ResMa® and

continues to do so every day.“

ResMa® is a browser-based software that centrally collects all

energy and production data via various interfaces. With its extensive

analysis and visualization functions, it enables far more than traditional

energy management, as users also gain detailed insights into

workflows and production processes. This helps ResMa® not only

monitor energy but also specifically improve the efficiency and quality

of operational processes.

The software combines energy management with comprehensive

evaluation, analysis, and visualization options — as a tool for process

optimization and their energetic requirements. Based on detailed

knowledge gained about processes and energy flows within the

company, potentials can be identified to optimize processes.

ResMa® also supports compliance with the requirements of the

Energy Efficiency Act, prepares CO₂ balances according to CSRD,

and systematically implements energy management according to

DIN EN ISO 50001. This creates a reliable data basis for more efficient

processes and regulatory security.

Weidmüller GmbH & Co. KG

D 32758 Detmold

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 41/73


c/o Analytik Jena

Analytik Jena supports again as a sponsor

Bunsen-Kirchhoff

Prize 2026 awarded

at analytica

At the analytica conference, the renowned

Bunsen-Kirchhoff Award for Analytical

Spectroscopy was presented on March 26,

2026. Analytik Jena is pleased to support

this long-standing, internationally esteemed

award again this year as a sponsor and

to promote the laureate with a prize money

of 3,000 euros.

The Bunsen-Kirchhoff Award is awarded

by the German Working Group for Analytical

Spectroscopy (DAAS) of the German

Chemical Society (GDCh) and recognizes

outstanding scientific achievements in the

field of analytical spectroscopy. It is one of

the most important recognitions for excellent

research in this field and is a central

component in promoting young scientists

in the advanced stages of their careers.

Prof. Dr. David Clases receives

the Bunsen-Kirchhoff Award 2026

This year, the award goes to Prof. Dr. David

Clases, University of Graz. He has distinguished

himself with his work in the field of

Element Mass Spectrometry, particularly

ICP-TOF-MS (inductively coupled plasma

time-of-flight mass spectrometry).

Prof. Dr. Clases is internationally regarded

as one of the most innovative young

researchers in analytical spectroscopy. His

research at the interface of ICP-MS, nanostructure

analysis, and hybrid measurement

methods has gained significant global attention

in recent years.

His groundbreaking contributions include,

among others:

- Further development of high-resolution

ICP-TOF-MS, enabling the simultaneous,

rapid, and highly accurate analysis of

complex particle systems.

- Multimodal approaches that combine

ICP-MS with complementary methods

such as optical trapping or Raman

spectroscopy – a crucial step toward

capturing both elemental and molecular

information in a single measurement.

- Significant advances in particle

characterization, relevant for

environmental analysis, materials

research, and biomedical questions.

With more than 70 publications, numerous

international awards – including the JAAS

Emerging Investigator Lectureship 2025 –

and a highly visible presence in scientific

committees and conferences, Prof. Dr. Clases

is considered a “Rising Star” in spectroscopy.

Judging Committee’s Statement

The DAAS judging panel, composed of representatives

from universities, research

institutes, and industry, sees a particularly

high scientific and technological added value

in Prof. Dr. Clases’s work. His research

significantly contributes to further developing

ICP-TOF-MS technology – a techno-

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 42/73


logy that, thanks to its multi-element capability

and coupling options, is regarded

as a key technology for future laboratory

analysis.

Opinions from the Scientific Community

Prof. Dr. Carsten Engelhard, Chairman of

DAAS and chair of the Bunsen-Kirchhoff

Award jury, emphasizes the importance of

the award:

“The Bunsen-Kirchhoff Award has a

long tradition and is highly regarded both

nationally and internationally. It recognizes

exceptional scientific achievements in analytical

chemistry, from optical spectroscopy

to mass spectrometric analysis. The work of

Prof. Dr. Clases is outstanding in its scientific

depth and practical relevance and possesses

high transfer potential for industry,

environmental, and materials analysis.”

Analytik Jena once again as a supporter

of scientific excellence

Analytik Jena is proud to have supported

the Bunsen-Kirchhoff Award for many years

and to contribute to promoting innovative

analytical research.

“The scientific insights recognized by

this award shape the further development of

analytical methods worldwide. As a technology

provider, we see it as our responsibility

to make cutting-edge research visible and to

support young scientists,” said Oliver Klaeffling,

Managing Director of Analytik Jena

GmbH+Co. KG.

About the Bunsen-Kirchhoff Award

The award is presented every two years and

targets outstanding researchers in the field

of analytical spectroscopy. It traces back to

a decades-long tradition within the GDCh

Working Group for Analytical Chemistry

and was first awarded in 1990. The ceremony

takes place during the analytica conference

in Munich.

Analytik Jena GmbH+Co. KG

D 07745 Jena

WIR MESSEN

NACH NORMEN

ISO 14644

VDI 2083

GMP

ANNEX 1

MEDIZINISCHE DRUCKLUFT

UND WEITERE EDELGASE

ISO 8573 + PHARMACOPEIA

C-tec Cleanroom-Technology GmbH

Tübinger Straße 47 D 72127 Kusterdingen

Tel.: +49 7071 6887180 Fax: +49 7071 688718700

E-Mail: public@c-tec.de www.c-tec.de

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe DE 05-2023 Seite 43/103


Fraunhofer ISIT strengthens its expertise in microfabrication:

Prof. Dr. Erica Lilleodden takes over the leadership

of the Microfabrication Processes business unit. The

materials scientist brings international experience from

research and institute management. At ISIT, she develops

manufacturing processes for microstructured systems and

microelectronics. The goal is to bring innovative microfabrication

faster into industrial applications and to strengthen

Europe‘s technological sovereignty.

New impulses for industrial

micro-manufacturing:

Prof. Dr. Erica Lilleodden heads

the business unit at Fraunhofer ISIT

The Fraunhofer Institute for Silicon Technology ISIT is strengthening

its expertise in microfabrication: Prof. Dr. Erica Lilleodden has

taken over the management of the Microfabrication Processes business

unit. With her international research experience and extensive

leadership expertise, she will drive the strategic development of this

central technology area.

Microfabrication as a key technology

for the next generation of microsystems

The Microfabrication Processes business unit is one of the largest

and most technologically central areas at Fraunhofer ISIT. The focus

is on developing and optimizing processes for the production of microstructured,

multi-material systems – especially for applications in

microelectronics and adjacent future fields.

„This business unit addresses the industrial requirements for

new manufacturing approaches for microstructured components

and systems,“ explains Lilleodden. „Our work benefits significantly

from close integration with other business units as well as from direct

access to the cleanroom infrastructure at the institute.“

International expertise meets applied research

Prof. Dr. Erica Lilleodden is an internationally experienced materials

scientist with positions in the USA and Germany. After earning her

doctorate at Stanford University, she worked at leading research institutions

such as Lawrence Berkeley National Laboratory and Sandia

National Laboratories.

In Germany, she shaped materials research for many years at the

Helmholtz-Zentrum Hereon and as a professor at the Hamburg University

of Technology. Most recently, she served as director of the

Fraunhofer Institute for Microstructure of Materials and Systems

IMWS in Halle (Saale).

With her move to Fraunhofer ISIT, she consciously combines

a change in perspective: „The role as business unit leader enables

much closer collaboration with scientists and industry partners on

an operational level,“ says Lilleodden. „I want to actively shape the

scientific strategy and especially expand the testing and diagnostics

area.“

Focus on process understanding, functionality, and reliability

A central differentiator of ISIT, according to Lilleodden, is the holistic

view of microfabrication processes: „We not only develop processes

but also identify new functionalities and specifically investigate

the reliability of the resulting systems,“ she says. „Diagnostic methods

play a crucial role here – especially to understand why components

work or don‘t.“

Response to increasing demands from industry and society

The requirements for microsystems are constantly growing – driven

by technological, economic, and societal developments.

„The pressure to innovate is enormous,“ emphasizes Lilleodden.

„Systems must be more powerful, sustainable, and at the same time

cost-efficient. These demands often stand in direct tension with

each other.“

Fraunhofer ISIT addresses these challenges through application-oriented

research and close cooperation with industry partners.

The goal is to align technologies early on with industrial requirements

and to transfer them efficiently into application.

Strategic role for microelectronics and European sovereignty

A particular focus is on strengthening microelectronics in Germany

and Europe. In the context of the Microelectronics Germany

research factory (FMD) and European initiatives like the EU Chips

Act, Lilleodden sees great opportunities for ISIT: „We will increa-

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 44/73


singly work on complex issues that are crucial for Europe‘s technological

sovereignty – for example, in prototype development, process

optimization, and wafer-level packaging,“ she says.

Leadership with a focus on collaboration and development

In her new role, Lilleodden relies on teamwork, interdisciplinary

exchange, and targeted support for young talent: „Everyone in the

team contributes with individual skills to overall success. It is crucial

to recognize these strengths and develop them together,“ she says.

She places particular importance on combining scientific excellence

with practical application: „Research at Fraunhofer means

translating knowledge into solutions that work in practice.“

Clear vision: technological leadership in microfabrication

For the coming years, Lilleodden has a clear goal: The Microfabrication

Processes business unit should be positioned as a leading

partner for innovative manufacturing technologies – nationally and

internationally.

„Our contribution to microelectronics is decisive,“ she summarizes.

„We develop technologies that enable future applications – from

AI to quantum technologies to medical sensors.“

Fraunhofer-Institut für Siliziumtechnologie ISIT

D 25524 Itzehoe

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe DE 05-2023 Seite 45/103


Independent award cements Vetter‘s position as a leading CDMO

Vetter awarded as winner at

the CDMO Leadership Awards 2026

– Important Industry Recognition for CDMOs

– Selection based on quantitative metrics and

verified reviews from the biopharma industry

– The award emphasizes the trust of the industry

and customers in Vetter

Vetter, a globally operating service provider for pharmaceutical and

biotech companies specializing in the manufacturing of essential

and life-enhancing medicines, receives the CDMO Leadership

Award 2026 as CDMO of the Year in the „Finished Dose“ category.

The award honors companies that stand out through exceptional

achievements in engagement, quality, and technical expertise, and

underscores Vetter‘s role as a reliable partner for the biopharma industry.

The award winners were announced during DCAT Week on

March 25, 2026, in New York.

“Our goal is to support our customers in the long term and according

to their needs,” says Lars Hahn, Senior Vice President of Global

Sales Organization at Vetter. “The award confirms our focus on the

highest quality, reliability, and collaborative partnership. Above all, it

recognizes the work of our more than 7,300 employees worldwide.”

Investments in Capacities and Technologies

The award reinforces Vetter’s important role as a strategic partner

in the development and manufacturing of injectable medicines.

The pharmaceutical service provider supports its customers across

the entire value chain, from process development through clinical

and commercial filling to a wide range of assembly and packaging

services. In light of continuously increasing demands on the manufacturing

processes of complex biological medicines, Vetter is expanding

its capacities, technological expertise, and quality systems:

Strategic investments in Europe and the USA strengthen the global

development and production infrastructure. Overall, the company

plans investments of around two billion euros by 2035.

Reputable Industry Award with Independent Data Basis

“The CDMO Leadership Awards represent much more than mere

recognition,” says Louis Garguilo, Editor-in-Chief of Outsourced

Pharma. “They reflect direct feedback from clients as well as the

practical experiences of companies that must succeed in an increasingly

complex development and production environment. The finalists

and winners this year have convincingly demonstrated that

they deliver reliably, continuously adapt to new requirements, and

act as trustworthy partners.”

The CDMO Leadership Awards are awarded annually by the media

group Life Science Connect and the trade publication Outsourced

Pharma and are among the prestigious industry awards. The basis

for the award is an independent study by the Boston-based Tufts

Center for the Study of Drug Development, which is based on quantitative

performance data and verified reviews from pharmaceutical

and biotech companies.

Vetter Pharma International GmbH

D 88212 Ravensburg

The Vetter team proudly accepts the award (from left): Dr. Sebastian Schuck, Vice President of Key Account Management, Lars Hahn, Senior

Vice President of Global Sales Organization, Ayse Hizli, Vice President of New Business Development, Michele Cavalheiro, Key Account Manager,

and Dr. Claus Feussner, Senior Vice President of Development Service. © Vetter Pharma International GmbH

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 46/73


Own subsidiary for the Spanish market

ENGEL Spain strengthens customer

proximity, service and access

to technology in Spain

With the rebranding of its former sales partner Roegele as ENGEL Spain, injection

moulding machine manufacturer ENGEL is expanding its direct presence in

the Spanish market. Since 1 April, the company has been represented in Spain by

its own subsidiary. For local plastics processors, this combines the continuity of

a team established on the ground for decades with direct access to the technology,

service and solutions portfolio of the global ENGEL Group – from injection

moulding machines and automation to digital assistance systems. ENGEL now

has its own subsidiary in the Spanish market.

Local continuity and global support

structures

Since 1972, Roegele has supported customers

in Spain in sectors such as automotive,

packaging, medical and technical moulding,

providing sales, service, training and consultancy

relating to ENGEL injection moulding

solutions. Building on this long-standing

partnership, the injection moulding

machine manufacturer is now taking the

next logical step. With ENGEL Spain, customers

will continue to work with the same

trusted contacts and benefit from the same

local market expertise. Service and application

engineering expertise will be integrated

even more closely into the corporate group’s

international network.

“The integration into the ENGEL Group

strengthens our local presence in Spain and

enables us to offer our customers even better

service and technical support,” says Daniel

Vizuete, Managing Director of ENGEL

Spain.

Barcelona site to be expanded

ENGEL is making targeted investments in

local structures, application engineering

and service capacity in Spain. At the Barcelona

site, a technical centre for training and

a showroom are being established. This will

strengthen ENGEL Spain’s local technical

support and shorten service response times.

For customers, the combination of local presence

and global connectivity will become

even more immediately accessible.

“With ENGEL Spain, we are creating

the conditions to support our customers in

the Spanish market even more directly and

to further develop our local presence in a

targeted manner,” says Benjamin Lettner,

VP Europe West & East. “In doing so, we are

building on long-established customer relationships

and an experienced local team.”

Broad portfolio for the Spanish market

Spain is one of Europe’s key plastics markets

and an important market for ENGEL in

south-western Europe. ENGEL has traditionally

had a strong presence here in the automotive

industry; at the same time, packaging

and the second brand WINTEC offer

further potential. For processors in Spain,

this expands access to solutions that are

both commercially and technically suited to

a wide range of market requirements. This

offering will also be showcased at Equiplast

in Barcelona in early June: ENGEL Spain will

present exhibits from the automotive, packaging

and technical moulding sectors, including

a tie-bar-less victory 120 with viper

20 linear robot, the all-electric e-mac 200

and e-motion 220, as well as the WINTEC t-

win 6500. The trade fair presentation will be

complemented by digital assistance systems

and connected production solutions.

Daniel Vizuete, Geschäftsführer ENGEL Spain

(Bild: Engel)

Benjamin Lettner, VP Europe West & East

(Bild: Engel)

ENGEL AUSTRIA GmbH

AT 4311 Schwertberg

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 47/73


The research group of Prof. Dr. Peter Neubauer combines robots, analysis devices,

and artificial intelligence into effective research teams

A laboratory without people

It sounds a bit like science fiction: a laboratory that can plan, conduct,

and evaluate its experiments largely independently. In which

computers and artificial intelligence (AI) control robots work together

with state-of-the-art analysis devices. And in which no human

has to burn the night hours feeding cells and keeping experiments

running. But exactly that has become a reality at the KIWI Biolab

at TU Berlin. The developers of the fully automated high-tech laboratory

will also make their know-how available in the new research

center „The Simulated Human“ (Si-M) of TU Berlin and Charité –

Universitätsmedizin Berlin.

„I‘ve always been interested in how to bring new biological processes

from the lab into practice as quickly as possible,“ says Prof. Dr.

Peter Neubauer, who heads the Department of BioProcess Engineering

at TU Berlin. The co-founder and director of the KIWI Biolab

is a trained microbiologist. So he initially asked himself questions

mainly regarding bacteria, yeasts, and fungi: How can such organisms

be best kept in bioreactors? In a way that they not only reproduce

and thrive well but also produce valuable substances, such as

specific proteins for the pharmaceutical industry?

Finding an answer to this is anything but easy. Because these

tiny manufacturers often react very strongly to their environment. In

a laboratory experiment at the milliliter scale, they may behave perfectly.

But that doesn‘t necessarily mean they will do the same in a

bioreactor with several hundred cubic meters of content. Therefore,

before industrial use, it is essential to determine under which conditions

which organisms can best perform the desired task.

Automated work in the laboratory

Model calculations can provide clues. How quickly does an organism

grow? How much substrate does it consume? Peter Neubauer and

his team compile these and many other parameters into mathematical

formulas. In the computer, different process variants can then be

compared to see which one yields the best results.

„But we can also connect such mathematical models with robots

and analysis devices,“ explains Peter Neubauer. In this way, work in

the lab can be organized and automated digitally. One type of robot,

for example, sucks a few milliliters of liquid from the bioreactor

at specific times. One of its mobile colleagues then transports the

sample to a measuring device that analyzes its properties. For this to

work, the technical helpers must coordinate their work so that each

does the right thing at the right moment. „For this, we need extensive

computer programs,“ says Peter Neubauer.

Extremely interesting for the pharmaceutical industry

But the effort is worth it. The KIWI Biolab is now one of the world‘s

leading laboratories for the development of bioprocesses. Through

the use of mathematical models and artificial intelligence, even

At KIWI Biolab, one of the world‘s leading laboratories for the development

of bioprocesses, a 48-bioreactor system integrated into a laboratory

robot is used, enabling the parallel cultivation and automated monitoring

of biological processes under controlled conditions.

complex experiments can be carried out fully automatically. The AI

decides, for example, when it makes sense to take a sample and then

initiates the necessary steps. It ensures that the organisms in the

bioreactor lack nothing, automatically maintaining temperature, pH,

and other influencing factors in the optimal range. This way, it controls

the process so that it delivers the maximum yield or a specific

quality of the desired product. It even recognizes when an experiment

is not going well, so it can be aborted, repeated, or modified.

„All of this is, for example, extremely interesting for the pharmaceutical

industry,“ says Peter Neubauer. Is it worthwhile to move

from the lab to application with a new product? Which of several

possible candidates is the most promising? And what will the optimal

process for production look like later? Such questions can be

answered much faster and more efficiently in the KIWI Biolab than

in a conventional laboratory.

Data marketplace for the biotechnology industry

No wonder, then, that Peter Neubauer and his team collaborate with

many pharmaceutical manufacturers on various projects. „Developing

a new drug costs an average of 2.5 billion US dollars and takes

ten to fifteen years,“ the researcher says. Every superfluous experiment

and every saved day benefits patients and companies alike.

From industry, a new challenge was also posed to the TU group.

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 48/73


„So far, we‘ve mainly dealt with processes involving microorganisms,“

explains Peter Neubauer. „But there is also great interest in

similar procedures for cell cultures.“ His working group will focus on

this in the future at the Si-M research center, where TU Berlin and

Charité – Universitätsmedizin Berlin cooperate.

Another focus will be the development of a data marketplace for

the biotechnology industry: What information must be recorded during

an experiment to ensure it can be reproduced? How should the

data be presented and offered to others so that they can understand

and utilize it? The team has gained extensive experience in such

questions over the years.

„From my point of view, we are not a core group at Si-M,“ the

scientist clarifies. Therefore, only a small part of his team will gradually

move to the new research center. „But our expertise is interesting

for many groups working there.“ Because robots and AI are likely to

play an increasingly important role in other laboratories in the future.

And to ensure that the technical research helpers do what they are

supposed to, much work remains for Peter Neubauer and his team.

The Research Center „The Simulated Human“ (Si-M)

On April 22, 2026, four years after groundbreaking, the doors of the

five-story research building „The Simulated Human“ will open. On

the campus in Berlin-Wedding, medical professionals, natural scientists,

and engineers from many disciplines of TU Berlin and Charité

– Universitätsmedizin Berlin will work closely together to develop

new therapeutic and diagnostic approaches for diseases. Bioanalytics,

organoid technologies, and methods for cell measurement are

intertwined with single-cell genetics, bioinformatics, automation,

and medical technology, often combined with other fields and excellence

clusters. Artificial mini-organs from human cells, fitting on

a chip, are intended to replace animal testing; by stitching together

interacting proteins, previously unknown processes in cells will become

visible.

Architecturally, the Si-M building already reflects the integrated

working atmosphere and the planned dialogue with the public: In

the light-filled central atrium with a café and a round lecture hall, an

impressive open staircase spirals upward. It leads to spacious laboratories

equipped with advanced technology such as mass spectrometry,

bioprinting, laser scanning microscopy, and others.

Further information:

The Department of Medical Biotechnology will also be represented

at the new Berlin research center „The Simulated Human“ with its

organoid research. Read here about the research of Prof. Dr. Sina

Bartfeld.

Technische Universität Berlin

D 10587 Berlin

Conveyor belts ensure a steady flow of materials in the medical technology sector and meet the

highest requirements for purity, precision, and integration into automated processes.

Conveyor belts in medical technology:

Precision and purity in focus

In medical technology, conveyor belts are a central component of

safe and stable production processes. They enable a consistent material

flow and help reduce errors and contamination risks.

Manufacturers face high demands: cleanroom compatibility,

ESD safety, vibration-free processes, and seamless integration into

automated systems are crucial. At the same time, conveyor belts

must be easy to clean and reliably protect sensitive components.

Montech offers specialized conveyor belt solutions that combine

precise transport, compact designs, and high reliability. Systems

like TB30 and TB40 enable exact positioning, stable workflows, and

flexible integration into various applications – from assembly to packaging

of sensitive products.

Efficient conveying technology for the high-precision medical industry.

(Copyright: MONTECH AG)

Montech AG

Gewerbestrasse 12

CH 4552 Derendingen

Telefon: +41 326815500

eMail: info@montech.com

Internet: https://www.montech.com

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 49/73


Final report — Growth in visitor numbers,

full halls, clear future topics:

analytica 2026 sets standards

– 1,135 exhibitors from 40 countries

– About 35,000 visitors from 115 countries

– AI and automation as innovation drivers for the industry

Full halls, more visitors, highly satisfied exhibitors: analytica

2026, held in Munich from March 24 to 27, impressively

demonstrated how innovative and forward-looking the

international laboratory industry is. 1,135 exhibitors from

40 countries presented their world premieres and new products

from the entire spectrum of laboratory technology,

analysis and biotechnology to about 35,000 visitors from 115

countries. Conversations at the stands and in the supporting

program were all about the digital, automated, and sustainable

laboratory—and mostly the hot topic of AI.

“With a noticeable increase in the number of visitors and exhibitors,

and a high share of international participants, analytica 2026 confirmed

its status again as a world-leading trade fair,” says Dr. Reinhard

Pfeiffer, CEO of Messe München. “It once again made the dynamism

and innovative strength of an industry visible that supplies the

essential basics for growth fields such as food and quality control, life

sciences, and environmental technology.”

“analytica 2026 consistently addressed the most important industry

topics in the exhibition area, at the conference, and in the

supporting program. That makes it a unique platform for making

trends tangible, imparting specialist knowledge, and providing

orientation for the future of the laboratory,” adds Exhibition Director

Approximately 35,000 visitors from 115 countries attended analytica 2026.

© Messe München GmbH

Susanne Grödl. “The positive response from exhibitors and visitors

shows that we struck a chord with that and provided important impetus

for the industry.”

Exhibitors report very positive outcome

The exhibitors were very satisfied with the trade fair and were often

continuously involved in discussions at the stands. Dr. Gunther

Wobser, Managing Partner of Lauda Dr. R. Wobser and new Chairman

of the analytica Advisory Board, sums up: “analytica 2026 impressively

reaffirmed its status as the most important international

meeting place for the industry.” For Sylveer Bergs, Managing Director

Thermo Fisher Dreiech, analytica is the platform which unites all

industry stakeholders: “It showcases high-end analytics, integrated

life science workflows, digital and automated labs, and sustainable,

regulated applications, reflecting the move from standalone instruments

to connected, data-driven end-to-end solutions.”

Mathis Kuchejda, Managing Director of Schmidt + Haensch and

Chairman of the Analytical, Bio and Laboratory Technology Division

at the industry association Spectaris, adds: “Despite a challenging

market environment in recent times, there is a mood of optimism in

the industry—underpinned by the high level of innovative strength

and positive prospects in the long term.” Experts anticipate an annual

growth rate of five percent for the global laboratory market in the

next few years. This development is being driven primarily by automation,

robotics, and rising investments, for example, in life sciences,

pharmaceutical research, and environmental analysis.

Major attractions: special shows on the modern lab

The usual extensive supporting program addressed hot topics in

the industry and made them accessible in lectures, discussion panels,

and special shows. The daily live demonstrations, such as the

Special Show Digital Transformation, were a major attraction. Organizer

Felix Lenk, CEO of SmartLab Solutions, is extremely positive

about how things went: “You could feel the enthusiasm of the trade

fair visitors not only during the live demonstrations but also in the

hundreds of individual conversations about AI, digitalization, automation,

and robotics.” Nearby in the Live Lab, the rows of seats for

spectators were also full several times a day when experts presented

typical work processes from modern everyday laboratory life. The

experimental presentations in the Lab Safety Forum, which illustrated

the risks involved in laboratory work complete with bangs and

smoke, were also popular. The Jobday on the last day of the trade fair

drew large crowds. It offered graduates and young professionals the

opportunity to find out about professional prospects in the industries

and get to know potential employers.

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 50/73


Scientific exchange at the highest level

There was intensive specialist discourse at the accompanying scientific

conference, which had over 2,000 participants. “Analysis is the

basis of all knowledge. That became clear once again at the analytica

conference, which networks industry and academia every two

years at analytica,” says Prof. Gertrud Morlock from the Justus Liebig

University Giessen, who gave a lecture on a sustainable miniature

laboratory system. “The analytica conference has become one

of the most important scientific conferences worldwide—we heard

that repeatedly in conversations,” says a delighted Susanne Grödl.

Many sessions addressed trends such as the digital and green laboratory,

and were, in some cases, at full capacity due to the excessive

demand. Other lectures dealt with topics such as detecting designer

drugs in forensics, innovative mass spectrometry procedures for the

botanical origin analysis of honey, or special analytical methods for

ancient manuscripts.

analytica 2026 in figures

1,135 exhibitors (2024: 1,066 exhibitors) traveled from 40 countries

and regions, 56 percent of them from abroad. The top ten exhibitor

countries were (in this order): Germany, China, the U.S., Italy, Great

Britain and Northern Ireland, the Netherlands, Switzerland, France,

India, and Spain. There were about 35,000 visitors (2024: 33,386 visitors)

from 115 countries and regions, and the share of international

visitors totaled around 40 percent. After Germany, the top ten visitor

countries were (in this order): Austria, Switzerland, Italy, Great Britain

and Northern Ireland, France, the Netherlands, Turkey, Poland,

Czech Republic and the U.S.

The next analytica will be held with the analytica conference

from April 25 to 28, 2028.

Messe München GmbH

D 81823 München

Regulatory milestone provides planning security for BBIT-based products

Vink Chemicals listed according

to Art. 95 for active ingredient BBIT

Vink Chemicals is officially listed for the active substance

BBIT according to Article 95 of the EU Biocidal Products

Regulation, thereby strategically expanding its portfolio.

With the achievement of this milestone, Vink Chemicals strengthens

its position as a reliable manufacturer of biocides and as a

solution provider that supports its customers with both active substances

and formulated systems.

BBIT is now the seventh active substance listed by Vink Chemicals

under Article 95 of the EU Biocidal Products Regulation. This

confirms and honors the company‘s long-term strategy to commit

to compliance with legal requirements, ensure supply security for its

customers, and continuously expand its portfolio.

Ingo Krull, Technical Sales Manager TB Europe at Vink Chemicals,

comments: „With Vinkocide® BBIT 97, Vink Chemicals completes

its active substance portfolio for water-miscible coolants.

Vinkocide® BBIT 97 was the last missing puzzle piece in our product

range. This means we now offer not only the active substance

BBIT but also a water-soluble formulation with Vinkocide® BB WM,

enabling the use of BBIT in all aqueous metalworking fluids.“

With the listing, Vink Chemicals now has the opportunity to offer a

range of high-performance products based on BBIT. These include

Activink® BBIT 97 (for formulators of biocidal products) as well as

Vinkocide® BBIT 97, which is used as a biocide in liquid concentrates

for metalworking and in the manufacture of silicone sealants.

Furthermore, Vink Chemicals offers ready-to-use formulations

based on BBIT: parmetol® BPX for household, industrial, and institutional

sectors (HI&I), paints & coatings, and coolants, as well as

Vinkocide® BB WM for post-treatment in metalworking fluids.

BBIT products now available

With the listing of Vink Chemicals, customers in Europe now have

a genuine alternative supplier, allowing them to diversify their procurement

risks. Vink Chemicals plans to further develop the market

through competitive conditions and reliable availability. Interested

companies can request samples immediately.

Vink Chemicals

D 21250 Tostedt

What customers now benefit from

Headquarters of Vink Chemicals in Kakenstorf near Hamburg.

(Image: Vink Chemicals)

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 51/73


The world-leading trade fair sends a strong message with global reach

and innovation power in a challenging market environment

PaintExpo: Worldwide, indispensable

meeting point for industrial

coating technology

Concrete projects, lively conversations, palpable energy – the PaintExpo

presented itself in 2026 at its most dynamic. Intensive discussions

took place in the halls, new contacts were made, and business

was initiated, driven by a high visitor frequency and an international

professional audience. The atmosphere: electrifying. And perhaps

the most surprising aspect: amidst a challenging economic situation,

a clear optimism prevailed, paired with a firm determination to actively

pursue the next steps. „Despite strikes in air traffic and difficult

economic conditions, PaintExpo 2026 was a complete success. It

once again demonstrated that the world’s leading trade fair for industrial

coating technology is the most important impulse generator

and an indispensable platform for the industry,“ explains Markus

Geisenberger, Managing Director of Leipziger Messe.

With 10,200 visitors from 68 countries and 425 exhibitors from

30 countries, it shows that even in its tenth edition, it enjoys very

high acceptance and attracts visitors from all over the world. It is the

must-attend event for new visitors and existing customers. Almost

45 percent of the guests do not participate in any other trade fair. „I

am very satisfied with the great public interest at PaintExpo 2026.

Our booth – as in previous years – was continuously well attended,

and we held many targeted high-level conversations. I am especially

impressed by the high international share of visitors,“ states Michael

Müller, CEO of the WAGNER Group.

PaintExpo has once again expanded its international significance:

the proportion of foreign exhibitors increased from 48 to 52

percent, which also affected the visitor structure. Almost 40 percent

of visitors traveled from abroad, making the fair a global meeting

point for the industry. Industry professionals from 68 countries used

the platform to gather information from companies in 30 different

countries, establish international business contacts, and explore

new markets. This strong international presence promotes crossborder

exchange of know-how and innovations. Thomas Querfurth,

Sales Coordinator for Germany at HangOn, confirms this: „There is

simply no other spot where you can gather in three exhibition halls

and meet all the necessary trades within a few days, exchanging the

latest technology. And this applies to companies from Japan to the

USA.“

Innovations shape the industry: The focus of this year‘s event

was particularly on sustainable, energy-efficient, and digitized coating

processes in the areas of powder coating, wet coating, dip coating,

and electroplating. Automation and the use of artificial intelligence

also defined the trade fair activities and reflected the current

industry requirements, which aim to simplify processes for users,

redefine standards, or increase flexibility. Numerous world and trade

fair premieres demonstrated how companies can make their processes

more economical and environmentally friendly at the same

time. „Personal exchange is especially important to us and cannot

be replaced by digital formats because only in individual conversations

can our technologies, solutions, and services be made visible

and tangible. But the PaintExpo is also relevant as a trend barometer.

Here we see which future application fields can be developed,“ adds

Matthias Haarer, Managing Director at Eisenmann.

Platform for exchange and business initiation: PaintExpo 2026

impressed not only with its comprehensive product and solution

offerings but also as a communication and business platform for decision-makers

and managing directors – after all, two out of three visitors

belong to the top decision-makers in their companies. Intensive

technical discussions, concrete project initiations, and active

exchange between providers and users characterized the trade fair

– a key success factor that has already led to high satisfaction among

exhibitors and visitors in previous events. 89 percent of exhibitors

state that they achieved their goals for participating in PaintExpo.

„PaintExpo simply manages to bring the entire industry to Karlsruhe

and offers a comprehensive showcase of surface technology.

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 52/73


For Krautzberger, PaintExpo is the most important trade fair there

is,“ explains Thomas Weidmann, Managing Director of Krautzberger

GmbH.

Focus on Nachwuchsförderung (young talent promotion): On

the final day of the fair, PaintExpo also emphasized the promotion

of young talents with its Career Day. Students and graduates received

targeted insights into industrial coating technology and could

directly contact companies. A compact program of lectures, guided

tours, and networking offered practical orientation regarding entry

opportunities and career paths. This strengthens PaintExpo’s role as

a platform for networking professionals and industry.

The focus is already on the next event: The upcoming PaintExpo

will take place from April 25 to 28, 2028, and already attracts interest.

Numerous exhibitors are already using the opportunity of rebooking

during the ongoing fair to secure their preferred spots early.

Leipziger Messe GmbH

D 04356 Leipzig

Redipor® Legionella agar plate range - specifically designed to support the detection

and enumeration of Legionella in water samples

New Legionella testing selective

agar plates launched by AnalytiChem

AnalytiChem’s new Redipor Legionella agar plates,

specifically designed to detect and count Legionella bacteria

in water samples.

AnalytiChem, manufacturer of specialized laboratory equipment,

reagents and consumables, has launched a new addition to its highquality

Redipor® microbiological prepared media portfolio. The new

Redipor Legionella Agar Plate range offers a suite of ready-to-use,

selective culture media options. These are formulated to support

ISO 11731-compliant Legionella culture workflows, enabling enumeration

of Legionnaires’ Disease-causing Legionella spp. bacteria as

colony-forming units (CFU) for regulatory reporting.

AnalytiChem’s new Redipor Legionella media range covers the

full culture pathway required for ISO-aligned testing, ensuring reliable

recovery, quality control, and compliance with international

standards. This makes it ideal for use in laboratories and organizations

responsible for water safety and regulatory compliance, including

environmental, public-health and industrial monitoring laboratories,

as well as water utilities.

Redipor Legionella media delivers a comprehensive range of ISO

11731–aligned culture media, designed for parallel plating on non-selective

and selective media, as required by ISO 11731 to maximize

recovery across diverse environmental sample types. Plate options

include BCYE (Buffered Charcoal Yeast Extract), GVPC (Glycine

Vancomycin Polymyxin Cycloheximide) and MWY (Modified Wadowsky-Yee)

agar variants with growth factors and selective agents,

and a cysteine-free option for comparative studies.

Each Redipor medium in the new range serves a distinct role

within the Legionella culture workflow: non-selective recovery

(BCYE), selective isolation (GVPC, MWY), and confirmation via

cysteine dependency. AnalytiChem experts can advise on the right

combination by application - from testing clinical respiratory specimens

(e.g. BAL, sputum) to differing environmental water or heavily

contaminated environmental samples, such as biofilms and cooling

tower sludge.

“Culture remains the internationally accepted reference method

for the detection, enumeration, and confirmation of Legionella

in water systems, forming the basis of regulatory compliance and

outbreak investigation,” said Nico van Stallen, Segment Director

Life Science & Lab Essentials, AnalytiChem. “Our new suite of ready‐to‐use

Redipor Legionella agar plates are designed to make this

workflow simple, consistent, and aligned with ISO 11731. This is the

benchmark international reference method for Legionella detection,

supporting official investigations and reporting.”

AnalytiChem’s Redipor ready-to-use culture media range not

only supports critical applications in Water testing, but also Pharmaceutical

quality control, Food & Beverage, and Healthcare sectors.

AnalytiChem Holding GmbH

D 65760 Eschborn

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 53/73


Interpack 2026: Stäubli presents a comprehensive robot

portfolio for hygiene-sensitive applications

Roboter für Food- und

Pharma-Packaging

At Interpack, Stäubli emphasizes its expertise in Food and

Pharma Packaging with groundbreaking innovations at

booth C38 in Hall 15. The manufacturer has expanded its

portfolio of hygienic four- and six-axis robots with a mobile

pharmaceutical robot capable of operating even under sterile

conditions – a true world first.

TX2-160 HE - Both the SCARAs

of the TS2 series and the TX2

six-axis robots prove themselves

in the wash-down version (HE)

configuration with food-grade oil

(H1) in all possible applications

in food manufacturing.

(Copyright: Stäubli Tec-Systems

GmbH Robotics)

With the Accesspharma program, which

focuses on environments of cleanroom class C,

Stäubli completes the circle with fast, reliable

automation solutions for non-aseptic areas.

(Copyright: Stäubli Tec-Systems GmbH Robotics)

In sensitive industries such as food, pharmaceuticals, and medical

technology, special regulations, specific standards, and strict hygiene

requirements apply. These entry prerequisites naturally create

a barrier to robot deployment. Therefore, standard robots are at best

found in secondary packaging areas.

For all other tasks, such as packaging open foods or filling liquids

into vials, robots that meet the strictest hygiene standards, including

sterilization, are required. Additionally, process safety, dynamics,

and precision are among the desired qualities.

With numerous model variants of four- and six-axis robots,

Stäubli can precisely meet these industry-specific requirements.

Now, the provider has further enhanced its unique robot portfolio

with two additional innovations. „At Interpack, we will present,

alongside two demo applications, the TX2-60L Stericlean+ in Hollow

Wrist design as well as the Sterimove, the world‘s first mobile

robot capable of working under sterile conditions. This is a milestone

for the pharmaceutical industry,“ says Peter Pühringer, Managing

Director of Stäubli Robotics.

Sterimove – a globally unique concept

Indeed, Sterimove is more than just an innovation. The mobile robot

makes a significant contribution to safer, more productive, and

more reliable pharmaceutical manufacturing. The device sets new

standards for mobile robotics in Class A/B/C/D environments. Sterimove

minimizes contamination risks from manual interventions,

increases productivity, and ensures safety and reliability in the most

sensitive environments. Thanks to its modularity, easy cleaning, and

contamination-free design, it is the ultimate solution for pharmaceutical

manufacturers seeking safety and operational excellence.

Special versions: From HE and H1 to Stericlean and Stericlean+

Both the SCARAs of the TS2 series and the TX2 six-axis robots perform

reliably in the wash-down configuration (HE) with food-grade

oil (H1) across all possible applications in food production. When it

comes to meeting aseptic conditions, these four- and six-axis robots

are also available in the Stericlean version. For direct use in isolators

within high-sterility pharmaceutical environments of GMP Class A,

Stäubli offers the suitable robot with the Stericlean+ variant.

For the first time at Interpack, Stäubli will present the TX2-60L

in Stericlean+ version with Hollow Wrist. „With these robots, the

engineers have pushed the hygienic design to the limit with a fully

enclosed structure from the base to the flange at the tip. The model

with hollow wrist offers unparalleled cleanability and improves

decontamination processes compared to the standard model,“ emphasizes

Pühringer. The cleaning processes are simplified, and the

robot‘s design additionally prevents particles from adhering to the

coating. The Stericlean+ option with Hollow Wrist for the TX2-60

and TX2-60L models is now available for order.

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 54/73


Practical demo applications

Fully automatic filling and packaging of radionuclides.

(Copyright: C-RayTherapeutics Group)

At Interpack, Stäubli will showcase the performance of its robots

through two application examples in the Food and Pharma sectors.

In an AI-optimized, robot-assisted food application, a TS2-80 SCA-

RA in HE and H1 versions demonstrates high dynamics in handling

unpackaged foods. A special feature: the SCARA is equipped with

a newly designed bellows made from material properties compliant

with FDA guidelines. This makes the robot suitable for direct contact

with food.

A second cell demonstrates the advantages of the recently introduced

Accesspharma series in the secondary packaging of pharmaceuticals.

With the Accesspharma program, focused on cleanroom

environment Class C, Stäubli completes the circle with fast, reliable

automation solutions for non-aseptic areas. This allows users to

avoid the significantly higher investment in more complex model

variants.

Stäubli Tec-Systems GmbH Robotics

D 95448 Bayreuth

Technical surface coatings for

3D-printed plastic parts

In mass production, 3D-printed parts are being used to an increasing

extent – not only for small batches and prototypes. Therefore, it

is of great importance that the surface quality of the parts is optimized

in every respect. With our processes and procedures, we bring

3D-printed components and housings to the level of commercial

parts in terms of appearance and function.

On one hand, regarding the visual appearance, which is especially

important for visible components. On the other hand, in many

cases, the technical properties of the surface of the parts are also significant.

Here, our diverse methods and variations of surface coating

are available to meet various requirements.

The surface technology that WÖHR covers includes

the following applications:

– Increasing chemical robustness

– Enhancing UV resistance

– High-ohmic ESD protection

– Low-ohmic EMC protection

Structurally, a coating can also offer advantages; depending on the

choice of coating, different surface textures from fine to coarse can

be applied to the workpieces.

Does your 3D part have the wrong color because the filament for

the 3D printer is not available in the desired shade? Our coating systems

allow for a free choice of color to match other components of a

device – even metallic-looking surfaces can be realized. We can also

vary the gloss level of the surface.

Defects in the surface, such as small holes or fine seam lines, can

be invisibly covered with a coating. With our expertise, we adjust the

surface of the coating so that cracks, holes, and seams are no longer

visible.

The advantage of all our coating technologies for our customers: they

receive ready-to-sell parts and components that are suitable even for

demanding users – including the renowned excellent quality of Richard

Wöhr GmbH.

Richard Wöhr GmbH

D 75339 Höfen/Enz

Oberflächenlackierung 3D-gedruckte Kunststoffteile – Vergleichsbild

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 55/73


34th Conference „Industrial Component Cleaning“, June 25 and 26, 2026

Ensure component cleanliness in

a process-safe and efficient manner

Changed requirements for the quality, cost-efficiency, and sustainability of components

demand adapted manufacturing technologies and processes – including

in component cleaning. As a leading knowledge platform in the German-speaking

region, the „Industrial Component Cleaning“ conference of FiT provides

relevant know-how, informs about trends and new developments in cleaning

technology. The event program with an integrated exhibition on June 25 and 26,

2026, at the Neckar Forum Esslingen also includes the presentation of the 5th

FIT2clean Award.

Increasingly rapid transformation processes

in industry pose challenges for manufacturing

companies. For example, producing

high-quality components and system parts,

including for sensor and analysis systems,

aerospace, semiconductors, optics, mobility,

medical and pharmaceutical technology,

security technology, defense, coating and

finishing technology, as well as energy technology,

requires optimized and new solutions

even in component cleaning. The processes

must ensure that defined, sometimes

extremely strict cleanliness specifications

are not only stable and cost-efficient but

also carried out in an energy- and resourcesaving

manner.

The 34th „Industrial Component Cleaning“

conference of the Professional Association

for Industrial Part Cleaning (FiT)

presents know-how, new process engineering

solutions and products, innovative

methods for process control, as well as bestpractice

applications. An integrated exhibition

and the presentation of the „FiT2clean

Award“ innovation prize complement the

program of this event, established as a leading

knowledge platform for component

cleaning. It will be held by fairXperts on June

25 and 26, 2026, at the Neckar Forum Esslingen.

Future-oriented cleaning

processes – what matters

The focus of the versatile two-day program

includes the areas of process chain for component

cleaning, media quality – process

water treatment, innovations, measure-

ment, testing, and control, as well as practical

examples. It offers numerous impulses

and shows strategies for adapting and optimizing

cleaning processes. Under the title

„From Sand in the Gears to Contamination-

Free,“ the importance of purity throughout

the entire process chain is examined, along

with general standards, guidelines, and

practical requirements. A presentation will

illustrate the conceptual and technological

challenges in designing high-purity cleaning

applications using a case study from medical

technology, where the cleaning system is

understood as a quality gate before the cleanroom.

The factors to consider when coordinating

forming processes, component

cleaning, and corrosion protection in battery

cell manufacturing are also discussed.

The agenda also features the introduction

of a world novelty for energy-efficient and

environmentally friendly laser cleaning of

mass-produced items such as screws, nuts,

or clips. Under the motto „Innovation Butane

Cleaning,“ participants will receive an

update on the latest developments of a new

cleaning process. Other topics include new

high-performance filters for component

cleaning and the efficiency advantages of

treating used rinse water through vacuum

distillation. Additionally, the conference will

inform about ways to increase cleaning efficiency

and recycling capability of process

water during vibratory finishing through

synergistic cleaning and flocculation systems,

as well as cost and resource savings in

Defines, partially extremely strict cleanliness specifications that are

both stable and cost-efficient as well as energy- and resource-saving,

for which the conference offers knowledge, innovations, and solutions.

(Image source: fairXperts GmbH & Co. KG)

The accompanying exhibition provides direct information

about new products, developments, and networking.

(Image source: fairXperts GmbH & Co. KG)

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 56/73


The event in brief:

34th „Industrial Component Cleaning“ Conference

Date: June 25 and 26, 2026

Location: Neckar Forum Esslingen, Hauffstraße, 73728 Esslingen

Information and registration: www.industrielle-reinigung.de, fairXperts GmbH & Co. KG,

Nicolas Herdin, nicolas.herdin@fairxperts.de

component cleaning through sensor-controlled

bath changes. New developments for

bath monitoring, such as a solution for mobile

measurement of ultrasonic power and

cleanliness control regarding particulate

and film cleanliness, will also be presented.

The benefits resulting from the interplay of

cleaning technology and new measurement

solutions along the process chain are illustrated

with practical examples. Just as the

consistent recording, evaluation, and interpretation

of process and cleanliness data

can enhance cleaning performance.

Furthermore, the decisive influence of

intelligent parts handling on cost efficiency

is highlighted. The question of what advantages

inline laser cleaning of aluminum diecast

electronic housings offers as an alternative

to decapping is answered by a practical

contribution.

Presentation of the FiT2clean

Innovation Award

As part of the conference, the €10,000 FiT-

2clean Award will also be presented. The innovation

prize will be awarded for the fifth

time on June 25. Prior to that, the three finalists

will present their submitted solutions to

the conference participants.

Accompanying exhibition

– networking at its best

An accompanying exhibition rounds off the

demanding lecture program. Participants

Fachverband industrielle Teilereinigung (FiT) e.v.

Geschäftsstelle

Hauptstraße 7

D 72639 Neuffen

Telefon: +49 7025 84340 Telefax: +49 7025 843420

eMail: info@fit-online.org

Internet: http://www.fit-online.org

Reingehört special, live from the lounges Karlsruhe 2026, the first episode of the year

with Dr. Jochen Kolb, Managing Director of BioChem Labor für biologische

und chemische Analytik GmbH, Karlsruhe

Reingehört - the podcast of the cleanroom

and process engineering industry

From the comprehensive analysis and

consulting services of BioChem, including

what the horseshoe crab has to do with bacterial

analysis, to home water filters – in this

episode, everything revolves around water.

What qualities does water have in pharmaceutical

production?

The podcast discusses, among other

things, the monographs of Ph. Eur., USP, and

JP and their differences. For example, Ph.

Eur. has recently included the rFC test in the

endotoxin LAL test monograph. This test is

more sustainable than the LAL and does not

rely on animal products.

BioChem also talks about problems in

the production and supply of water in pharmaceutical

manufacturing (e.g., biofilm).

will have the opportunity to learn about new

products and developments in industrial

cleaning technology and to exchange experiences

directly with experts.

The conference is aimed at specialists

and managers, engineers, and technicians

from development and design, technology,

process engineering, work preparation,

manufacturing, production planning, and

quality management from various industries.

The complete program of the 34th „Industrial

Component Cleaning“ conference,

further information, and registration forms

are available at www.industrielle-reinigung.de.

https://open.spotify.com/episode/3kJIw2U-

RY4N4bPD7sxAvIo?nd=1&dlsi=02e2f133499c4675

BioChem Labor für biologische und chemische Analytik

GmbH

Daimlerstr. 5b

D 76185 Karlsruhe

Telefon: +49 721 9737-0

eMail: biochem@biochem.de

Internet: http://www.biochem.de/

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 57/73


With SynTiso, developed together with two major pharmaceutical companies,

Syntegon offers the solution for increasingly strict regulations

aimed at eliminating contamination risks in injectable medicines.

interpack 2026: „re:imagine Your Factory

of the Future“ – with the strategic

lifecycle partner Syntegon

– The „Factory of the Future“ of pharmaceutical, biotech,

and food companies must address urgent industry challenges

– Automation, robotics, digitalization, and AI enable users

to focus on value-adding tasks

– Syntegon‘s contribution to „re:imagine Your Factory of the Future“:

neXt, SVX, SynTiso – supported by lifecycle services

At interpack 2026, Syntegon will reimagine the „Factory of the Future“

together with its customers (re:imagining) and present solutions

to their most pressing challenges. With highly innovative solutions,

the company will demonstrate at stand A31–B31 in Hall 6 how

processes in the pharmaceutical, biotech, and food industries can be

elevated to the next level of efficiency, flexibility, and sustainability.

Challenges as Drivers

for Innovation and Growth

The industry is undergoing a groundbreaking transformation: Due

to increasing cost pressures, growing flexibility requirements, and

stricter regulations, companies must rethink the „Factory of the

Future.“ Syntegon addresses these challenges through innovations

developed jointly with customers. The vision: a factory that regulates

itself and adapts to all challenges, overseen by an AI-supported

human control center. At interpack 2026, Syntegon will present the

building blocks that enable customers to rethink their „Factory of the

Future“ – with processes that are smoother, smarter, contactless, and

ultimately more efficient.

„At interpack, we demonstrate the strength of our COCREA-

TE and COSUCCEED concepts. Breakthrough innovations developed

together with customers lead to greater business success.

Our highlights neXt and SVX set new standards in the food sector.

In pharmaceutical production, SynTiso sets a new standard as the

first of its kind: a glove-free high-speed line for filling liquid medicines.

Syntegon‘s promise as a strategic lifecycle partner combines

industry leadership with top-tier lifecycle services as the

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 58/73


The new neXt system solution from Syntegon addresses the industry‘s

challenges by offering seamless operation, smart performance, and

contactless control.

ultimate enabler for our customers‘ growth,“ says Torsten Türling,

CEO of Syntegon.

neXt: The „Factory of the Future“ is smooth, smart,

and contactless

The food industry is developing rapidly: consumer and retailer demands

change overnight, requiring maximum flexibility. Workforce

shortages and rising costs, along with regulations demanding more

sustainable packaging materials, are pressing issues. Syntegon‘s

new system solution neXt addresses these challenges with seamless

operation, smarter performance, and contactless control. The neXt

automation allows users to focus on value-adding activities.

Smooth processes increase efficiency and minimize downtime.

Real-time data drive fact-based decisions and optimized OEE. Contactless

operation and intuitive user interfaces lead to faster changeovers,

reduced training efforts, and higher flexibility across the entire

product portfolio. Looking ahead to future requirements, neXt gives

food manufacturers a competitive advantage in a dynamic market.

SVX: High speed, quick changeovers,

low material consumption

The highly innovative vertical packaging platform SVX sets new

standards in meeting current and future customer requirements. Its

impressive speed of 300 bags per minute enables the lowest cost per

bag. Switching between different bag formats is simple, quick, and

ensures maximum availability and flexibility. Patented technology

reduces packaging material consumption by 50 percent. The compact

footprint of the SVX significantly increases productivity per

square meter without requiring additional production space, thereby

supporting business growth.

SynTiso: Redefining liquid

pharmaceutical production

Pharmaceutical and biotech are growth industries. Most new biologics

are delivered as injectable preparations. Stricter regulations

aim to eliminate contamination risks in injectable drugs. Syntegon

offers the solution with SynTiso: developed jointly with two major

The highly innovative vertical packaging platform SVX sets new

standards in solving today‘s and future customer requirements.

pharmaceutical companies, SynTiso eliminates the need for human

intervention through glove-free isolator technology and fully robotic

operation, including contactless transport systems. The advantages:

compliance with the highest regulatory standards, 50 percent faster

changeovers, and higher batch outputs. SynTiso is ready to revolutionize

the future of liquid drug filling.

“re:imagining Your Factory of the Future”

with Lifecycle Services

Syntegon is the strategic lifecycle partner for its customers. Its comprehensive

application expertise supports companies in the pharmaceutical,

biotech, and food industries from the initial idea stage

for their „Factory of the Future.“ Engineering solutions tailored to

the specific business needs create the best return on investment.

Flawless project execution from start to production enables faster

market entry. Qualified service engineers on-site ensure reliable

performance and high availability. Continuous line upgrades based

on AI-supported data analysis make every investment future-proof.

Syntegon‘s lifecycle services turn the equipment of any „Factory of

the Future“ into a valuable and reliable business asset.

Syntegon Technology GmbH

Blaufelder Straße 45

D 74654 Crailsheim

Telefon: +49 7951 4020

eMail: packaging-ph@syntegon.com

Internet: http://www.syntegon.com

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 59/73


Arburg Technology Days 2026

The leading information platform

for all plastics processors

– A success: The industry’s largest in-house event worldwide, attracting around 3,750 visitors

– arburgSOLUTIONworld: Practical solutions, high performance and 40 machine exhibits

– Highlight: New electric Allrounder Trend machines receive an enormous response

Around 3,750 visitors from 44 countries attended the Arburg Technology Days from 11 to 13 March 2026, dedicated entirely

to arburgSOLUTIONworld. This industry highlight once again impressed with its tried-and-tested concept of opening the

doors of Arburg’s central headquarters in Lossburg to its German and international customers. With more than 40 machine

exhibits and a wide range of practical applications, innovative processes, smart automation, as well as digital services,

software and after-sales offerings, Arburg demonstrated its capabilities in every respect – from standard to high-end. The

company presented itself across the entire value chain as an innovative solution provider and as a competent and reliable

partner.

The guests were thoroughly delighted to learn more about the present

and future of injection moulding – from the new electric Allrounders

Trend through special exhibition areas dedicated to medical

technology, sustainability, automation and turnkey solutions, to

specialist presentations, a comprehensive service area and insights

into the state-of-the-art assembly line for the Trend machines. There

was also ample opportunity for networking and for one-on-one

discussions with the experts from Arburg and its partners.

Once again, unique for the entire industry

“Presenting the wide range of solutions – the unique blend of technology,

processes and services – all in one place makes the Arburg

Technology Days the ‘home of injection moulding’, a showcase for

plastics processing and a magnet for customers from all over the

world”, summarised Juliane Hehl, Managing Partner Global Marketing

and Business Development at Arburg. “Nowhere else is such

a wealth of information concentrated in such a customer-focused

way. We see ourselves as a highly reliable partner who cultivates

the best possible business relationships over the long term. With us,

everyone finds exactly the right answers to their individual injection

moulding questions of today and tomorrow. We had many fruitful discussions

and received substantive enquiries about our machines,

services and solutions”.

Dr Christoph Schumacher, Vice President Global Marketing,

adds: “These Technology Days are a fixture in the trade fair calendars

of our customers and prospective clients. The high level of

commitment and customer focus shown by each and every one of

us leaves an extremely positive overall impression. This makes a visit

to the Technology Days an experience within and alongside the Arburg

family.”

Hands-on experience: Allrounder Trend highlight

Ein Highlight unter den rund 40 Maschinen-Exponaten der

Arburg Technologie-Tage 2026 waren die elektrischen Allrounder

Trend – der neue Standard im Spritzgießen. (Foto: ARBURG)

Five exhibits of the electric Allrounder Trend demonstrated how rapid

set-up and simple operation enable the efficient production of

plastic parts. The new standard machines are available worldwide.

At the market launch in spring 2026, four machine sizes with clamping

forces ranging from 500 to 2,000 kN will be available. The following

exhibits could be experienced live:

– A typical application for technical injection moulding was the

production of free-falling, angled insulators for automotive wiring

harnesses on an electric Allrounder 1000 e Trend.

– An automated Allrounder 1000 e Trend attracted a great deal of

attention as it produced the “Donut-ella” – a practical USB cable

winder – from PA material recycled from abandoned fishing nets.

The gadget was the winner of the Italian “Pleiades” design competition

of the IUAV University of Venice. Arburg supports this

competition with machine technology; other partners include

Uniform (mould) and Ewikon (hot runner).

– An electric Allrounder 500 e Trend produced reusable coffee

cups made from coffee grounds. The bio-based compound and

tool for this came from the Danish start-up Grounded.

– The efficient production of 9,200 LSR closures per hour was

demonstrated on a production cell centred around an Allrounder

1800 e Trend with a 64-cavity tool from ACH Solution and a linear

Multilift Select 16.

– The new Gestica lite control system for the Allrounder Trend also

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 60/73


attracted enormous interest from visitors. It is simple and intuitive

to use and features a clear, centralised dashboard that is easy to

understand. This makes the machine much easier to oerate, even

for non-specialists.

Automation and turnkey solutions take centre stage

Skills shortages and labour costs are increasingly pointing a spotlight

at customised automation and turnkey projects into focus. Arburg

sees itself in every respect as a “problem solver”, finding turnkey

solutions that keep unit costs to a minimum without compromising

maximum quality in any way. The turnkey experts offer expertise tailored

to the specific case of application and support the customers

throughout the entire value chain, from the initial idea to the finished

product. Several customer projects and Arburg exhibits demonstrated

succinctly, how ingenious ideas and efficient automation can

be put into practice.

To showcase this, e. g. a turnkey system centred around a vertical

Allrounder 475 V produced covers for radio keys as an example.

Here, overmoulding with PC/ABS recycled material combined

with in-mould decoration (IMD) creates a high-quality surface. Part

handling and re-working are carried out by a Kuka six-axis robot integrated

into the Gestica control system.

– One benchmark project is the digitally interlinked turnkey system

for injector pens, the “NextGen Medical Solution”, centred

around an Allrounder 570 A electric machine in cleanroom version.

This production cell was realised through the collaboration

of Arburg (machine technology), Hack Formenbau (mould technology),

Hack Digital Solutions (mould monitoring), HB-Therm

(temperature control units) and a renowned OEM. It impresses

with a holistically optimised, cost-effective, compact configuration

characterised by high availability, productivity, part quality

and energy-efficiency.

– An Allrounder 370 A electric injection moulding machine demonstrated

how medical products can be manufactured in an

ISO Class 7 clean room under the most stringent of hygiene standards.

The dual-cavity pilot mould from partner Fostag can be

scaled up to a large number of mould cavities once the part design

has been finalised.

– A cost-effective investment is to connect a clean room-rated

machine to the clean room via an extended tunnel conveyor belt.

This was demonstrated on an electric Allrounder 520 A. Using a

96-cavity tool from partner Kebo, around 60,000 needle caps for

insulin pens made from PP (Borealis) were produced per hour.

These were then fed into the clean room on an enclosed conveyor

belt.

– Using a demo part for microfluidics, a hydraulic Allrounder 520 S

demonstrated, a simple, reliable and cost-effective way of manufacturing

medical products from PVC, known as a difficult material

to process.

– Is there a reliable process for achieving shot weights of just 0.016

grams? This is precisely what a production cell based around

an electric Allrounder 270 A set out to demonstrate. The machine

was equipped with a size 5 micro injection module and

an 8-millimetre injection screw and it showcased the sprueless

production of four micro-filters, each weighing 0.004 grams and

featuring complex geometries.

High levels of public interest across the board

570A NextGen Medical Solution (Foto: ARBURG)

Focus on Medical: Diverse clean room solutions

Arburg had set up a dedicated “Medical Corner” for the expanding

medical sector. This showcased some pioneering exhibits from the

field of medical technology – developed by Arburg and renowned

partners: stand-alone solutions, a production cell docked to a clean

room, and production directly within that clean room – an appropriate

concept to meet every requirement.

Other key areas of the Arburg program also proved very popular

with visitors. Considerable interest was shown in digital services

and software across the entire value chain. Many of these solutions

enable customers to minimise their operating costs and thus save

money. Here, Arburg provides support with its combined expertise

in digitalisation, smart manufacturing and artificial intelligence. The

Gestica lite control system, Arburg’s own MES (ALS) and the arburgXworld

customer portal were presented. In addition, the added

value of innovative digital pilots and assistants was demonstrated on

Allrounder exhibits.

In the arburgGREENworld exhibition area, the company demonstrated

what it has to offer in terms of processing recycled materials

and alternative plastics, as well as the activities contributing

to resource conservation and the implementation of a functioning

circular economy.

The wide range of Application Technology services was also

showcased, including on-site consultancy, fault analysis and process

optimisation. In the service area, the range of services covering the

entire machine lifecycle was on display. Here too, the focus was on

‘ease of use’. These machines are easy to operate and maintain. This

enables even relatively inexperienced operators to manufacture products

of the highest quality. The maintenance of the new Allrounder

Trend, predictive maintenance, comprehensive after-sales support

and Ready2Go used machines, as well as modern training methods,

were demonstrated.

The technical presentations on all three Technology Days were

complemented by interesting expert talks. These offered practical

insights – from reliable injection moulding and the path to the

Smart Factory right through to the latest Allrounder Trend machines.

And last but not least, the factory tours were also very well received.

Among other things, interested visitors were able to find

out in detail about the new Allrounder Trend production concept

and gain interesting insights into the highly automated production

at Arburg.

ARBURG GmbH + Co KG

D 72290 Loßburg

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 61/73


The pharmaceutical and valve

industry – a marriage

for life

In order to eliminate the

risks associated with manual

handling, SISTO Armaturen S.A.

developed an automatic media

panel as a compact, flow-optimised

multi-way block diaphragm valve.

(Source: KSB / SISTO)

Everything communicates with everything else – in the

pharmaceutical industry, this type of production process

has long been more than just a vision for the future. Already,

artificial intelligence and the digital transformation are

streamlining the first pharmaceutical plants. Good news for

an industry which in many countries is one of the important

pillars of their economy.

The pharmaceutical industry is accelerating the digital transformation

of its laboratories in order to make them more efficient and

sustainable. “Large pharmaceutical companies are planning to nearly

double their investments in laboratory transformation by 2025

– from 4 percent today to as much as 7 percent of their turnover,” the

Capgemini Research Institute (CRI) reports. Almost 75 percent of

drug companies have already started modernising their laboratories.

“Cost pressure and international competition are increasing,”

explains the Baelz company, a provider of valves, actuators and sensors

and more. In order to remain competitive in a challenging environment,

the focus is therefore increasingly on digitisation. “It is

indispensable both for the use of valves and the management of our

plant park,” reports Baelz. Everything communicates with everything

else.

Sanofi also continuously invests in its facilities. The goal is, among

other things, to strengthen Europe‘s supply security in the

pharmaceutical sector. (Photo: Sanofi)

Automation and digitisation as a key

Automation and digitisation are progressing – a development also

observed by Baelz. For example, a pharmaceutical company invested

around 275 million Euros into a highly automated model factory for

the treatment of cancer and cardiovascular conditions. “Thanks to

With FLOWave, Bürkert has brought a hygienic, material-saving and yet

very accurate flow sensor to the market. The focus was on conserving

resources. (Photo: Bürkert Fluid Control Systems)

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 62/73


its modular design, you can quickly expand or convert production,”

says Baelz.

A Baelz pure steam generator station was designed specifically

in order to provide live steam for the production of drugs in their new

production building. “Sophisticated control and safety functions as

well as integrated automatic desalination and sludge removal ensure

a smooth and economical operation,” explains Baelz.

Optimising energy needs

Increased energy prices are proving a challenge for the pharmaceutical

industry. The sector is therefore taking action and installing

new plant or optimising existing systems with regard to their energy

requirements. Against this background, Bürkert has developed products

that are not just more energy-efficient to manufacture, but

also reduce energy consumption in subsequent use. Therefore, Bürkert

is continuously investing into the development of components.

In addition, the company is also trying to think of system solutions

that offer increased added value to their customers. An example of

this is their FLOWave flow sensor: “The use of an innovative physical

sensor principle has enabled us to launch a hygienic, material-saving

and very accurate flow sensor.”

Sterile, aseptic and hygienic processes

A variety of pharmaceutical processes require safety valves in a variety

of materials and sizes. “Especially in the core processes for the

end product, there is a need for special valves that offer easy process

integration with the option of cleaning (CIP) or sterilisation (SIP),”

explains the valve manufacturer LESER. “Safety valves for these applications

must avoid external contamination.”

With their Clean Service series, LESER has developed safety

valves “that meet all the requirements of the pharmaceutical industry”.

Its small dead space and gap-free interior construction

allow for “a high degree of cleanliness”. During the cleaning process,

valves can be opened automatically using the existing pneumatic

lift.

For use in sterile, aseptic and hygienic processes, valves must

meet high requirements. Since product and process safety is a top

priority in these applications, the GEA industry group has equipped

its aseptic valves with a hermetic sealing element to prevent

microorganisms entering a sterile process. Numerous valve types

are required. The spectrum ranges from shut-off, double-seat and

tank valves to an extensive portfolio of special valves.

Fast, safe and cost-effective

Faced with a strong and changing pharmaceutical industry, valves

are in great demand. SISTO Armaturen S.A. for example, which is

part of the KSB Group, has developed an automated media panel solution

for the production of immunosuppressants for a French pharmaceutical

company. In order to eliminate the risks associated with

manual handling, SISTO developed the media panel as a compact,

flow-optimised multi-way block diaphragm valve. Equipped with

pneumatic drives and electronic feedback units, it automates and

streamlines production processes. “This allows them not just to be

run faster and more safely, but also more cost-efficiently,” emphasises

SISTO.

Investments into modern pharmaceutical plant

The willingness of the pharmaceutical sector to adapt to industry

growth involving increasing requirements by means of investments

is great. There are numerous projects to demonstrate this. With an

investment volume of almost 300 million Euros, Pfizer has expanded

its existing plant into one of the world‘s most modern production facilities

for the pharmaceutical industry in accordance with Industry

4.0 standards. In their “HighCon” factory, drugs for the treatment of

diseases such as cancer, cardiovascular conditions and Covid-19 are

efficiently manufactured for the global market.

The HighCon system facilitates a highly automated and at the

same time sustainable production process. Pfizer: “All machines and

processes are intelligently networked using information and communication

technologies, enabling the Freiburg Pfizer plant to produce

in a faster, more flexible and resource-efficient way.”

Strengthening supply security

In the construction of new facilities, Sanofi also

emphasizes a high degree of automation and the highest

sustainability standards. (Photo: Sanofi)

In Frankfurt, Sanofi is building a state-of-the-art insulin production

facility around 36,000 square meters in size. “The aim is to secure

the long-term supply of vital insulin and to strengthen the European

security of supply,” explains the company. The investment amounts

to about 1.3 billion Euros by 2029. This system will also be largely

automated and is designed to meet the highest sustainability standards.

Merck is also investing sustainably. The company is expanding

its ADC production capacity in St. Louis, USA, by investing 70 million

Euros. Capacities for the production of ADCs (antibody-drug

conjugates) for cancer patients will be tripled, and laboratories modernised.

Such investments by the pharmaceutical industry are also

investments into people’s recovery. The valve industry is part of a

marriage for life, sometimes also helping to save lives in their role as

a supplier.

Trends and highlights from the valves industry can be experienced

at VALVE WORLD EXPO from 1 to 3 December 2026 in Düsseldorf.

Current industry and product information can be found on the

internet portal at www.valveworldexpo.com.

Messe Düsseldorf GmbH

D 40001 Düsseldorf

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 63/73


Hose and injection molding solutions from Germany | Medical technology expertise

Masterflex Group Medical Solutions

at MedtecLIVE 2026 in Stuttgart

Masterflex Group Medical Solutions: Medical Tubing,

Injection Molding & Assemblies from a Single Source

Plastics are indispensable in medical technology: they enable safe,

reliable, and cost-effective solutions for applications with high requirements

for functionality, documentation, and quality. As Masterflex

Group Medical Solutions, Novoplast Tubing Technology from

Halberstadt and Fleima-Plastic from Wald-Michelbach develop and

manufacture high-quality medical tubing, connectors, injectionmolded

parts/form parts, as well as customer-specific assemblies for

demanding medical applications.

Medical Technology: Development Partner,

Manufacturer, Supplier, and Exhibitor

„Our precise plastic components are used in infusion, dialysis, endoscopy,

enteral nutrition, and also in hearing aids, among others.

A particular advantage for development and purchasing teams: For

many years, we have successfully combined extrusion and injection

molding in complex medical technology projects – thus creating innovative,

economical system solutions from a single source,“ says

Martin Oye, Managing Director of Medical Technology at Novoplast

Tubing Technology and Fleima-Plastic.

Exhibitor at Medical Technology at MedtecLIVE with T4M 2026

Novoplast Tubing Technology will showcase at MedtecLIVE with

T4M 2026 (May 5-7, Hall 3/303) how demanding medical plastic

components can be reliably brought into series production, from

marking to validation. One focus is laser marking under cleanroom

conditions (ISO 14644): this creates durable, wipe- and abrasion-resistant

markings on tubing and plastic components, such as graduations

or serial and batch numbers. Additionally, the Medtec brands of

the Masterflex Group support tool and production relocation in injection

molding – with clear project structure and a consistent focus

on process stability. Complementarily, Novoplast offers validation of

plastic components and downstream processes: compliant, fast, and

audit-proof, as an important contribution to reliable market release.

The German Medtec brands position themselves as trusted

development partners for medical plastic components and support

projects from concept to series production – including project

management, feasibility analyses, and assistance with quality and

regulatory issues.

Free Tickets for MedTec 2026 Medical Technology Trade Fair

Novoplast Tubing Technology invites you to a personal exchange at

MedtecLIVE with T4M 2026 in Stuttgart: whether you want to clearly

mark a product, need a customer-specific injection molding component

or a secure tubing solution, or seek support with validation

and process setup, you can discuss these topics directly with the experts

on site. Hall 3 | Stand 303 (May 5–7, 2026).

Masterflex Group

D 45891 Gelsenkirchen

(Copyright: Masterflex SE)

Medical technology - Fleima-Plastic & Novoplast Schlauchtechnik, booth

3056 at MD&M West 2025, Anaheim. (Copyright: Masterflex SE)

Trade fair stand POV (Copyright: Masterflex SE)

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 64/73


The new PowerPulse CNp with

ultrasound requires only 2.2 m² of floor

space and features full-current filtration and

separate infrared vacuum drying. (Photo: LPW)

New from LPW: PowerPulse CNp system with ultrasound

High Performance

in the Production

Environment

Requires minimal floor space and offers maximum High Purity technology:

the new PowerPulse CNp with ultrasound from LPW Reinigungssysteme

GmbH. The compact, semi-automatic system was

designed for demanding industrial applications in production environments

and offers high performance, especially at low throughput

rates, high-quality auxiliary processes, and in sensitive manufacturing

areas.

The PowerPulse CNp is designed as a multi-stage system and

functions as a complete unit with manual batch handling. It combines

impulse vacuum through cyclic nucleation (CNp) and ultrasound.

Both methods can be used simultaneously or selectively

depending on the cleaning task. Additionally, the system features

an integrated full-stream filtration that ensures stable process conditions

and supports near-production, low-maintenance operation.

Another essential component is the integrated vacuum infrared drying

as a standalone process stage. It is an integral part of the concept

and enables efficient and quality-assured results, even for sensitive

or demanding components.

Dirk Konzok, Sales Manager and Authorized Signatory at LPW:

„We have responded to the increased demand from our customers

for a simple semi-manual CNp ultrasound system that can do much

more than previous solutions. Now we are bridging the gap between

laboratory technology and near-production cleaning. The new LPW

product stands for a practical approach to high-quality cleaning of

complex geometries: powerful, flexible, and tailored to the requirements

of modern manufacturing processes.“

The system is particularly suitable for demanding tasks in areas

such as medical technology, additive manufacturing, or general industry.

Typical application fields include cleaning medical devices,

capillaries, and stents, de-powdering additively manufactured components,

and cleaning complex geometries after post-processing.

Additionally, pre- and intermediate cleaning processes in subtractive

manufacturing are possible.

The tanks have a capacity of 55

liters for cargo carriers up to Schäfer

size 2. (Photo: LPW)

Technical data overview:

The new LPW system is available for experiments

at the company‘s location in Riederich.

LPW Reinigungssysteme GmbH

Industriestraße 19

D 72585 Riederich

Telefon: +49 7123 38040

eMail: info@lpw-cleaning.de

Internet: http://www.lpw-cleaning.de

The control panel can be operated

intuitively, also via a tablet or smartphone.

(Photo: LPW)

- Floor space: approx. 2.2 m²

- Dimensions (D × W × H): 760 × 2,812 × 1,496 mm

- Connection power: 35 A / 15 kW

- Filter / heating circuit: approx. 1.2 m³/h

- Heating capacity: circuit approx. 3 kW, tank approx. 2 kW

- Ultrasound power: approx. 9 W/l

- Tank volume: 55 liters

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 65/73


With the TDS501, E+E Elektronik introduces a next-generation dew point sensor. The sensor enables

continuous dew point measurement with auto-calibration without signal interruption, thereby

laying the foundation for reliable 24/7 process control.

TDS501 from E+E Elektronik: Continuous

dew point measurement down

to −70 °C Td without signal freezing

Industrial drying processes, especially in battery manufacturing, place the highest demands on dew point measurement.

At very low moisture levels, even the smallest deviations can affect product quality, yield and safety. This makes a stable,

continuous measurement signal essential. With the TDS501, E+E Elektronik presents its latest development for dew point

measurement: continuous measurement thanks to auto-calibration based on a new four-element measuring method, dew

point monitoring down to −70 °C Td, and smart protection concepts. The sensor therefore supports reliable around-theclock

process monitoring and efficient dehumidification control.

New: Four-element measuring method

Typical process events such as opening doors and airlocks or load

changes require a stable measurement signal. A frozen or heavily

averaged signal during auto-calibration can create blind spots in the

process in such environments. The TDS501 was therefore developed

around a key requirement in the control of very low dew points: auto-calibration

must not interrupt the measurement signal. In highly

dynamic applications, control decisions are made continuously. A

signal that freezes during calibration can conceal real process deviations

precisely when they matter most. To address this, the TDS501

uses an innovative new technology based on a four-element measuring

method with robust capacitive sensing elements. The

aim is to provide continuous dew point information for

24/7 process monitoring and therefore stable control

loops.

Dew point monitoring down to −70 °C Td

for demanding industrial drying

With the TDS501, E+E Elektronik extends its dew point portfolio

to measuring ranges down to −70 °C Td. This makes the sensor suitable

for applications in which extremely low moisture is a critical process

variable. These include battery manufacturing and the drying

of plastic granulate. In such processes, stable dew point monitoring

helps reduce moisture-related scrap, define safety

margins more precisely and control dehumidification

efficiently.

Smart protection concepts and

configurable filter caps

Seasonal fluctuations, plant shutdowns or component

failures can cause short-term condensation

in compressed air systems. The TDS501 is

designed to remain reliable even under such atypical

conditions and to reduce condensation-related

drift through practical design features. These include

robust sensing elements, a sintered stainless steel filter

and a durable stainless steel construction.

As standard, the TDS501 is equipped with a stainless

steel filter that offers a balanced ratio between protection and

response time. For cleanroom applications, where particularly

fast response times are required, an open filter cap is available as

an option. It further improves response time and allows even earlier

detection of dew point deviations.

Reproducible measurement results up to 80 bar

The TDS501 from E+E Elektronik.

(Photo: E+E Elektronik Ges.m.b.H.)

When dew point becomes a control variable, the measurement signal

must remain consistent even under changing operating conditions.

The TDS501 combines high repeatability with an accuracy of ±2

°C Td, supporting stable and reproducible production conditions. It

is also designed so that typical changes in process temperature do

not affect the measurement result.

With a pressure rating of up to 80 bar, the sensor can be installed

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 66/73


directly where the process takes place. This provides a robust basis

for process control and quality assurance in industrial compressed

air application.

The TDS501 is more than a sensing element in a housing. It is a

holistically developed measurement system in which the sensing

element, electronics, mechanical integration, installation and adjustment

are optimally matched to one another. For users, this means

stable, repeatable measurement results and a reliable basis for

process decisions across devices, batches and operating conditions.

An optimally matched measurement system

for reliable performance

E+E Elektronik Ges.m.b.H.

Langwiesen 7

AT 4209 Engerwitzdorf

Telefon: +43 7235 6050 Telefax: +43 7235 6058

eMail: info@epluse.com Internet: http://www.epluse.com

SPETEC® Laminar Flow Boxes for Laboratory, Research, and Industry

A cleanroom exactly

where it is needed

rooms in these cases is often associated

with disproportionate structural and financial

effort.

With the Laminar Flow Box FBS, Spetec

offers a solution for the targeted creation

of local cleanroom conditions directly

at the workstation. The systems generate a

The requirements for particle- and germfree

work environments are continuously

increasing. Especially in laboratories,

research facilities, as well as in industrial

manufacturing and packaging. In many applications,

cleanroom conditions are only

needed locally. Building complete cleanuniform,

vertical laminar airflow, enabling

controlled air quality within a clearly defined

workspace.

Depending on the model variant, a Laminar

Flow Box FBS covers an effective

cleanroom area of approximately 0.37 to

1.12 sqm. HEPA filters of type H14 are used,

which filter out at least 99.995% of all particles

— based on a particle size of 0.12 μm

according to MPPS. This results in a significant

improvement in air quality compared to

the ambient air and creates the conditions

for cleanroom standards up to ISO Class 5.

The Laminar Flow Box FBS is available

in various sizes and can be used as both a

freestanding unit and a table version. The

construction is made exclusively from cleanroom-compatible

materials such as anodized

aluminum and acrylic glass. The

systems have been tested by the Fraunhofer

Institute for Production Technology and

Automation.

Thanks to its modular design, the Laminar

Flow Boxes can be flexibly integrated

into existing work environments — without

structural modifications and with minimal

installation effort.

Spetec Gesellschaft für Labor- und Reinraumtechnik

mbH

Am Kletthamer Feld 15

D 85435 Erding

Telefon: +49 8122 959090

Telefax: +49 8122 9590955

eMail: info@spetec.de

Internet: https://www.spetec.de

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 67/73


For maximum flexibility

KEL-ERM VARIO from icotek:

Cable entry with variable

separation plates

The KEL-ERM VARIO is an advancement of the proven icotek cable entry system

and has been specifically designed for the entry of cables with and without connectors.

Different configurations can be easily implemented without replacing

the frame: With the plug-in separator bars, the frame can be individually adapted

to each application.

The KEL-ERM VARIO is easy and safe to

install. The modular system is based on a

clear structure and reduces the variety of

options to one frame size per version. Fewer

required components mean less storage and

procurement effort, while planning, design,

and assembly are simplified. For control cabinet

construction and device integration,

it offers additional flexibility. Thanks to the

variable filling, the KEL-ERM VARIO is suitable

for various requirements, from series

applications to customer-specific solutions.

Depending on the need, it can be equipped

with a different number of large or small

glands.

Automatic gland fixation

Depending on the gland used, cables with

diameters from 1 to 16 mm (single glands

KT1 to KT15) or 16 to 35 mm (single glands

KT16 to KT34) can be safely fed, sealed, and

strain-relieved. The cable glands are automatically

fixed in the frame during assembly.

After complete filling, the end cap is

securely screwed on. The KEL-ERM VARIO

is compatible with standard connectors for

10-, 16-, and 24-pin heavy-duty connectors.

The size KEL-ERM VARIO B is designed

for connectors measuring 46 x 46 mm (e.g.,

for controllers, counters). Thanks to the injected

seal and the use of single glands, the

high protection class IP65 is maintained

even with flexible configurations.

The advantages at a glance:

– Only one frame size for different

variants (e.g., 24|10, 24|7, 24|4)

– Maximum flexibility through plug-in

separator bars (included)

– High protection class IP65 thanks

to injected seal

– Maintains the integrity

of pre-assembled cables

– Quick retrofitting and easy

service work

– High packing density and a wide

variety of glands

– Strain relief according

to DIN EN 62444

– High stability and vibration resistance

– Very easy filling

– Compatible with IMAS-CONNECT

adapter glands

Less complexity, higher system

availability

The KEL-ERM VARIO allows processes to

be simplified, costs to be reduced, and the

entire product lifecycle to be optimized.

Optionally, the KEL-ERM VARIO is also

available with integrated threaded bushings

– perfect for mounting on the inside of enclosures

and ideal for vandalism protection

or unintentional loosening.

icotek GmbH

D 73569 Eschach

The new cable entry KEL-ERM-VARIO from icotek offers maximum flexibility in configuration. (Image: icotek GmbH & Co. KG)

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 68/73


New sensor technology for autonomous cleaning robotics in dynamic operational environments

Cleanfix is the first company to rely on the

3D ultrasound sensor ADAR from Sonair

The Swiss manufacturer of professional cleaning systems

Cleanfix is the first OEM partner to integrate the 3D ultrasonic

sensor ADAR from the Norwegian company Sonair

into the new generation of its autonomous cleaning robot

RA660 Navi XL. The solution is designed for use in open

and shared environments.

Autonomous cleaning robots are increasingly part of regular operations

today – often unattended, at night, and in areas also used by

humans. They encounter changing conditions: limited visibility, moisture,

dust, as well as small or ground-level obstacles in their path.

Against this background, Cleanfix has specifically further developed

the perception systems of the RA660 Navi XL. A central component

is the 3D ultrasonic sensor ADAR, which enables reliable

obstacle detection even under conditions that are challenging for

optical or laser-based sensor systems.

“Our customers do not evaluate algorithms, but results,” says Roger

Kaiser, Head of Robotics at Cleanfix. “Stable operation, minimal

interruptions, and a system that works reliably for hours are crucial.

This is exactly where ADAR comes in – as a prerequisite to make

autonomous cleaning scalable in everyday life.”

“For Sonair, this integration is an important step towards broader

application of 3D ultrasound in robotics,” adds Knut Sandven,

CEO of Sonair. “Service robotics is one of the fastest-growing areas

of automation. At the same time, these systems are increasingly working

in environments shared with humans instead of isolated industrial

facilities. In such scenarios, robust environment perception is

essential for reliable and predictable operation.”

Reduced sensor technology through 3D ultrasound

instead of individual sensors

With ADAR, Cleanfix replaces multiple linear ultrasonic sensors

with a central 3D sensor unit. By bundling these into a single sensor,

system complexity and the number of components are significantly

reduced.

This directly impacts integration and operation: The 3D ultrasonic

sensor provides spatial environment data that supports navigation

and movement behavior in real time. As a result, the robot

reliably detects small or partially concealed obstacles at ground level

– such as bags, pallet edges, or tools, which are common in practice.

Data protection is also considered systemically: Since no imaging

data is recorded or stored, the robot can be used in sensitive

environments.

High availability through low-maintenance sensors

and stable operation

Since the RA660 Navi XL does not rely on optical sensor systems

with sensitive lenses, regular cleaning is unnecessary. This minimizes

downtime and service effort, increasing availability during daily

operation.

Furthermore, false interpretations (“false positives”), such as

caused by dust particles, occur much less frequently. As a result, the

RA660 Navi XL operates more evenly and with fewer interruptions,

directly impacting productivity and area coverage.

The operation is independent of ambient light, making it suitable

for use at night or in poorly lit areas.

Outlook: Safety certification for 3D ultrasound

In the future, the safety-oriented use of the technology is also gaining

importance: Sonair is currently working on a safety certification

according to PL d (ISO 13849) / SIL (IEC 61508). This represents an

important step for the use of 3D ultrasonic sensors in safety-critical

applications and addresses the increasing requirements for autonomous

systems in shared environments.

This integration into the cleaning robot RA660 Navi XL marks

a first step in the industrial application of Sonair’s 3D ultrasound

technology.

Sonair

N 0484 Oslo

(Copyright Cleanfix)

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 69/73


Product Update BRXH: Optimized Lubrication, Better Sealing, More Precision

Rodriguez revises profile

rail guides for mechanical

engineering and robotics

Rodriguez now offers the profile rail guides of the BRXH series in an optimized version. The update includes three key

points: an expanded lubrication concept, a new sealing system, and higher precision. This makes processes even safer while

maintaining system compatibility.

Proven properties remain:

– Four ball rows in X arrangement with

45° pressure angle for load capacity

in all main directions

– Variants A, B, AL, BL, BS as well as

versions with and without flange

– Existing coatings still available

– Metal cover band usable

– Rail lengths up to 3,900 mm

– Interchangeability within a accuracy

and preload class

Higher accuracy becomes standard

Rodriguez GmbH now offers the BRXH series profile rail guides in an optimized version.

(Image: Rodriguez GmbH)

With the adjustments to its profile rail

guides BRXH, Rodriguez responds to the

increased demands in machinery construction

and automation. The fundamental

technical data remains unchanged, targeted

optimization steps increase process safety

and ensure longer service life and reproducible

precision.

More lubrication points

for uniform supply

The guide carriages now feature additional

lubrication points, through which the lubricant

is better and more evenly distributed

within the ball circulation unit. The systems

are still delivered pre-lubricated. When lubricating

from above, an adapter ensures

targeted distribution within the carriage.

New sealing concept

for demanding environments

A central element of the revision is the new

sealing system. Standardly, face seal double

lip seals and double lip longitudinal seals are

used, effectively protecting against particles

and contamination. Optional additional variants

are available: non-abrasive seal, additional

abrasive seal, and metal scrapers.

The previous normal accuracy class N is

eliminated. Instead, class H becomes the

new standard. The tolerances for height and

width have been reduced by approximately

50 percent compared to the previous N

version. Accuracy class P is now only available

upon request. The Z2 class in preload is

eliminated; Z0, Z1, and Z3 remain available.

Specifically, this means: higher repeatability

– especially relevant in robotics and automation

– and better parallelism, i.e., multiple

guides run more smoothly in parallel.

Other design adjustments

Additionally, the ground running surfaces of

the carriages have been increased from two

to three. For the rails, protective caps made

of plastic or optionally brass are available.

Rodriguez GmbH

D 52249 Eschweiler

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 70/73


www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe DE 05-2023 Seite 71/103


Veranstaltungen im Mai 2026

Für mehr Informationen oder zum Anmelden einfach auf die Veranstaltung klicken

12.05.2026 Seminar Oberflächen in der Medizintechnik

Veranstaltungsort: Ostfildern, Veranstalter: Technische Akademie Esslingen e.V.

18.05.2026 - 20.05.2026 Symposium 2026 ISPE Annex 1 Symposium

Veranstaltungsort: Lyon (FR), Veranstalter: ISPE

19.05.2026 - 21.05.2026 Seminar Pharma-Ingenieur/in (PT 25) - Block I

Veranstaltungsort: Mannheim, Veranstalter: CONCEPT HEIDELBERG GmbH

19.05.2026 - 19.05.2026 Workshop Performance Workshop Reinraum-Praxis

Veranstaltungsort: Reinraum Training Ceneter Frankfurt, Veranstalter: Cleanroom Future GmbH

20.05.2026 - 21.05.2026 Tagung 16. Fachtagung: Technische Sauberkeit in Montage- und Produktionsprozessen

Veranstaltungsort: Heidenheim, Veranstalter: Ultima Media Germany GmbH

20.05.2026 Seminar Praxis-Seminar für neue Teammitglieder: Kontaminationskontrolle und Arbeiten im Reinraum

Veranstaltungsort: München, Veranstalter: comprei Reinraum-Handel und Schulungs GesmbH

Veranstaltungen im Juni 2026

Für mehr Informationen oder zum Anmelden einfach auf die Veranstaltung klicken

02.06.2026 Seminar GMP-News 2026

Veranstaltungsort: Rheinfelden (CH), Veranstalter: Swiss Cleanroom Concept GmbH

04.06.2026 Webinar Annex 1 - Erfahrungen und Praxisbeispiele

Veranstaltungsort: Online, Veranstalter: PTS Training Service

09.06.2026 - 10.06.2026 Seminar Life Science Ready Days 2026

Veranstaltungsort: Karlsruhe, Veranstalter: Systec & Solutions GmbH

09.06.2026 - 10.06.2026 Seminar Fachgerechte Verlegung von nora Kautschukböden: Unterboden bei Wandbelägen &

Abdichtung von Nassbereichen

Veranstaltungsort: Weinheim, Veranstalter: nora systems GmbH

10.06.2026 - 11.06.2026 Seminar Bestimmung von Messunsicherheiten nach GUM

Veranstaltungsort: Hamburg, Veranstalter: Testo Industrial Services GmbH

10.06.2026 - 11.06.2026 Training & Schulung GMP-Reinraumschulung für aseptische Bereiche

Veranstaltungsort: Osnabrück, Veranstalter: Piepenbrock Dienstleistungen GmbH + Co. KG

11.06.2026 - 12.06.2026 Seminar Environmental Monitoring - Compliant and Reasonable

Veranstaltungsort: Kopenhagen, Veranstalter: CONCEPT HEIDELBERG GmbH

11.06.2026 Seminar Hygiene

Veranstaltungsort: Affoltern am Albis, Veranstalter: PTS Training Service

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 72/73


Veranstaltungen im Juni 2026

Für mehr Informationen oder zum Anmelden einfach auf die Veranstaltung klicken

15.06.2026 - 19.06.2026 Seminar Kalibriertage Thermodynamik: Prüfmittelmanagement und Kalibriertraining

Veranstaltungsort: Kirchzarten bei Freiburg, Veranstalter: Testo Industrial Services GmbH

16.06.2026 - 18.06.2026 Webinar GMPs for Equipment, Utilities and Facilities - Live Online Training

Veranstaltungsort: online, Veranstalter: CONCEPT HEIDELBERG GmbH

16.06.2026 - 17.06.2026 Seminar Klinische Prüfung mit Prüfpräparaten: GMP / GDP bei der Herstellung und Logistik

Veranstaltungsort: Alzenau/Digital, Veranstalter: PTS Training Service

17.06.2026 Seminar Aktualisierung und Auffrischung für Reinraum-Servicetechniker/-innen Neues in der

Mess- und Gentechnik, GMP & Co.

Veranstaltungsort: Krefeld, Veranstalter: IHK Mittlerer Niederrhein

17.06.2026 - 19.06.2026 Seminar Validierungsbeauftragte/r in der pharmazeutischen Industrie (QV 16)

Veranstaltungsort: Hamburg, Veranstalter: CONCEPT HEIDELBERG GmbH

17.06.2026 - 17.06.2026 Webinar PUPSIT - Erwartung & Umsetzung - Live Online Seminar

Veranstaltungsort: online, Veranstalter: CONCEPT HEIDELBERG GmbH

18.06.2026 Seminar GCP ICH E6 R3 und EMA Guidelines - Computersystemvalidierung und Datenintegrität

Veranstaltungsort: Siegburg, Veranstalter: PTS Training Service

23.06.2026 - 25.06.2026 Seminar Pharma-Ingenieur/in (PT 25) - Block II

Veranstaltungsort: Hamburg, Veranstalter: CONCEPT HEIDELBERG GmbH

23.06.2026 Seminar Räume, Luft und Technik: Gestaltung und Qualifizierung von Räumen

Veranstaltungsort: Online, Veranstalter: PTS Training Service

24.06.2026 Seminar Räume, Luft und Technik: Lüftungsanlagen

Veranstaltungsort: Online, Veranstalter: PTS Training Service

25.06.2026 Seminar Schleusenkonzepte im Reinraum: GMP-Praxis erleben mit 3D-Simulation

Veranstaltungsort: Online, Veranstalter: PTS Training Service

25.06.2026 Seminar Räume, Luft und Technik: Messtechnik, Umsetzung gemäß Annex 1 neu und DIN ISO 14644

Veranstaltungsort: Online; Veranstalter: PTS Training Service

25.06.2026 - 26.06.2026 Tagung 34. Fachtagung „Industrielle Bauteilreinigung“

Veranstaltungsort: Esslingen; Veranstalter: Fachverband industrielle Teilereinigung (FiT) e.v.

30.06.2026 - 01.07.2026 Webinar Annex 1 Intensive Training Course - Live Online Training

Veranstaltungsort: online; Veranstalter: CONCEPT HEIDELBERG GmbH

Impressum:

W.A. Schuster GmbH / reinraum online · Mozartstraße 45 · D 70180 Stuttgart · Tel. +49 711-9640350 · Fax 9640366

info@reinraum.de · www.reinraum.de · GF Dipl.-Designer Reinhold Schuster · Stgt, HRB 14111 · USt.-IdNr. DE 147811997

Originaltexte und Bilder:

Die namentlich gekennzeichneten Beiträge stehen in der Verantwortung des jeweiligen Autors. Nachdruck, auch auszugsweise, nur mit Genehmigung

der Redaktion und mit Quellenangabe gestattet. Für unaufgefordert eingesandte Manuskripte und Abbildungen übernimmt der Herausgeber keine

Haftung. Dem Herausgeber ist das ausschließliche, räumliche, zeitliche und inhaltlich eingeschränkte Recht eingeräumt, den Beitrag in unveränderter

oder bearbeiteter Form für alle Zwecke beliebig oft zu nutzen oder Dritten zur Nutzung zu übertragen. Dieses Nutzungsrecht bezieht sich auf Print- und

elektrische Medien (Internet, Datenbanken, Datenträger aller Art).

www.reinraum.de | www.cleanroom-online.com NEWSLETTER | Ausgabe EN 05-2026

Seite 73/73

Hurra! Ihre Datei wurde hochgeladen und ist bereit für die Veröffentlichung.

Erfolgreich gespeichert!

Leider ist etwas schief gelaufen!