BB - DIfE

20
Drittmittelprojekte
External Funding
Untersuchung zu den Mechanismen
der Anti-Adipositas-Effekte von Epigallocatechingallat
(EGCG) aus grünem
Tee an einem Mäusemodell
Finanzierung: Stiftung, Vitamehr
Laufzeit: 01.03.2005 – 31.12.2005
TEAVIGO – Effects of TEAVIGO on fat and
glucose metabolism in mice via stable
isotope technique
Finanzierung: Industrie
Laufzeit: 10.05.2006 – 31.03.2007
Stabil-Isotopenhäufigkeit (13C, 15N) in
Proteinen und Aminosäuren der Haare
vom Menschen – Möglichkeiten zur
Nutzung als Biomarker für die Abschätzung
der Proteinernährung als
Basis epidemiologischer Risikobewertungen
Finanzierung: DFG
Laufzeit: 01.01.2005 – 31.12.2006
Ausgewählte Publikationen
Selected Publications
Originalarbeiten/Original Papers
Boschmann, M., Adams, F., Schaller, K.,
Franke, G., Sharma, A. M., Klaus, S., Luft, F.
C., Jordan, J.: Hemodynamic and metabolic
responses to interstitial angiotensin II
in normal weight and obese men. J.
Hypertens. 24, 1165–1171 (2006).
Jürgens, H.S., Schürmann, A., Kluge, R.,
Ortmann, S., Klaus, S., Joost, H.-G., Tschöp,
M.H.: Hyperphagia, lower body temperature,
and reduced running wheel activity
precede development of morbid obesity in
New Zealand obese mice. Physiol.
Genomics 25, 234–241 (2006).
Kanzleiter, T., Schneider, T., Walter, I., Bolze,
F., Eickhorst, C., Heldmaier, G., Klaus, S.,
Klingenspor, M.: Evidence for Nr4a1 as a
cold-induced effector of brown fat thermogenesis.
Physiol. Genomics 24, 37–44 (2005).
Klaus, S.: Increasing the protein: Carbohydrate
ratio in a high-fat diet delays the
development of adiposity and improves
glucose homeostasis in mice. J. Nutr. 135,
1854–1858 (2005).
Klaus, S., Pültz, S., Thöne-Reineke, C.,
Wolfram, S.: Epigallocatechin gallate attenuates
diet-induced obesity in mice by
decreasing energy absorption and increasing
fat oxidation. Int. J. Obes. Relat.
Metab. Disord. 29, 615–623 (2005).
Klaus, S., Rudolph, B., Dohrmann, C., Wehr,
R.: Expression of uncoupling protein 1 in
skeletal muscle decreases muscle energy
efficiency and affects thermoregulation
and substrate oxidation. Physiol. Genomics
21, 193–200 (2005).
Klipstein-Grobusch, K., Möhlig, M., Spranger,
J., Hoffmann, K., Rodrigues, F. U. S.,
Sharma, A. M., Klaus, S., Pfeiffer, A. F. H.,
Boeing, H.: Interleukin-6 g.–174G>C promoter
polymorphism is associated with
obesity in the EPIC-Potsdam Study.
Obesity 14, 14–18 (2006).
Petzke, K. J., Riese, C., Klaus, S.: Short-term,
increasing dietary protein and fat moderately
affect energy expenditure, substrate
oxidation and uncoupling protein
gene expression in rats. J. Nutr. Biochem.
18, 400–407 (2007).
Petzke, K. J., Boeing, H., Klaus, S., Metges C.
C.: Carbon and nitrogen stable isotopic
composition of hair protein and amino
acids can be used as biomarkers for animal-derived
dietary protein intake in
humans. J. Nutr. 135, 1515–1520 (2005).
Petzke, K. J., Friedrich, M., Metges, C. C.,
Klaus, S.: Long-term dietary high protein
intake up-regulates tissue specific gene
expression of uncoupling proteins 1 and
2 in rats. Eur. J. Nutr. 44, 414–421 (2005).
Thone-Reineke, C., Kalk, P., Dorn, M., Klaus,
S., Simon, K., Pfab, T., Godes, M., Persson, P.
Unger, T., Hocher, B.: High-protein nutrition
during pregnancy and lactation programs
blood pressure, food efficiency, and body
weight of the offspring in a sex dependent
manner. Am. J. Physiol. Regul. Integr.
Comp. Physiol. 291, R1025-R1030 (2006).