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A SHORT COURSE IN THE MODELING OF CHEMOTAXIS

A SHORT COURSE IN THE MODELING OF CHEMOTAXIS

A SHORT COURSE IN THE MODELING OF CHEMOTAXIS

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Contents<br />

List of Figures iii<br />

1 Introduction 1<br />

1.1 What is Chemotaxis? . . . . . . . . . . . . . . . . . . . . . . . . . . . 1<br />

1.2 The Story of Dicty . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3<br />

1.3 Beyond Dicty . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4<br />

2 Modeling: The Macroscopic Approach 7<br />

2.1 The first derivation by Keller and Segel . . . . . . . . . . . . . . . . . 7<br />

2.2 The Keller-Segel Model of Chemotaxis . . . . . . . . . . . . . . . . . 14<br />

2.3 Traveling bands of chemotactic bacteria . . . . . . . . . . . . . . . . . 15<br />

2.4 Some conclusions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20<br />

3 Modeling: The Microscopic Approach 22<br />

3.1 A Local Information Model . . . . . . . . . . . . . . . . . . . . . . . 25<br />

3.2 A Barrier Model . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29<br />

3.3 A Nearest Neighbor Model . . . . . . . . . . . . . . . . . . . . . . . . 30<br />

3.4 A Gradient-Based Model . . . . . . . . . . . . . . . . . . . . . . . . . 33<br />

3.5 Chapter Conclusions . . . . . . . . . . . . . . . . . . . . . . . . . . . 34<br />

ii

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