- Page 2 and 3: BIMM118 Definitions • Pharmacolog
- Page 4 and 5: BIMM118 History of Pharmacology •
- Page 6 and 7: BIMM118 Homeopathy • 1790-96: Dr.
- Page 8 and 9: BIMM118 • Aspirin® - first synth
- Page 10 and 11: BIMM118 New Drug Discovery • Anal
- Page 12 and 13: BIMM118 New Drug Discovery • Desi
- Page 14 and 15: BIMM118 Patent Protection of new Dr
- Page 16 and 17: BIMM118 • Brand Name Drug Nomencl
- Page 18 and 19: BIMM118 • Safety Drug Approval -
- Page 20 and 21: BIMM118 • Regulatory bodies (FDA)
- Page 22 and 23: BIMM118 Drug Efficacy - Dietary Sup
- Page 24 and 25: BIMM118 Establishing Safety and Eff
- Page 26 and 27: BIMM118 • Pharmacokinetics Precli
- Page 28 and 29: BIMM118 Toxicity Testing • Mutage
- Page 30 and 31: BIMM118 • Animal Studies: Toxicit
- Page 32 and 33: BIMM118 Premarketing Clinical Studi
- Page 34 and 35: BIMM118 Phase I Studies • Used to
- Page 36 and 37: BIMM118 • Main clinical trial Pha
- Page 38 and 39: BIMM118 Phase III Studies • Measu
- Page 40 and 41: BIMM118 Adverse Reactions to Drugs
- Page 42 and 43: BIMM118 Drug Administration and Abs
- Page 44 and 45: BIMM118 Oral Drug Administration
- Page 46 and 47: BIMM118 Oral Drug Administration
- Page 48 and 49: BIMM118 Percutaneous Drug Administr
- Page 50 and 51: BIMM118 Percutaneous Drug Administr
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BIMM118 •Eye Drops •Sterile; Is
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BIMM118 Parenteral Drug Administrat
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BIMM118 Drug Distribution
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BIMM118 Drug Distribution - Interna
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BIMM118 Drug Distribution Drug conc
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BIMM118 Bioavailability: Drug Distr
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BIMM118 Drug Distribution Rate of E
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BIMM118 Half-life (t 1/2 ) [min]: D
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BIMM118 Loading Dose: Drug Distribu
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BIMM118 BLOOD LEVEL TOXIC LEVELS Ma
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BIMM118 BLOOD LEVEL TOXIC LEVELS Ma
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BIMM118 Drug Metabolism and Elimina
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BIMM118 • Phase I Reactions Phase
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BIMM118 Drug Metabolism - Phase I
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BIMM118 Drug Metabolism - Oxidation
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BIMM118 Drug Metabolism - Oxidation
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BIMM118 Aromatic hydroxylation: Ali
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BIMM118 Drug Metabolism - Oxidation
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BIMM118 Monoamine Oxidases (MAO): D
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BIMM118 Hydrolysis reactions Ester
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BIMM118 Drug Metabolism - Phase II
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BIMM118 Drug Metabolism - Glucuroni
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BIMM118 Drug Metabolism - Glucuroni
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BIMM118 Sulfation: Drug Metabolism
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BIMM118 Drug Metabolism - Other con
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BIMM118 Drug Action: Receptor Theor
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BIMM118 Four major drug targets: Dr
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BIMM118 Drug Targets
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BIMM118 Drug Targets: Receptors
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BIMM118 Receptors Many other types
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BIMM118 Sources of Ca ++ : Calcium
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BIMM118 Calcium as Second Messenger
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BIMM118 Ca ++ Sensors: • Annexins
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BIMM118 Calcium as Second Messenger
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BIMM118 - Smooth muscle: Calcium as
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BIMM118 • Immune response: Calciu
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BIMM118 G-Proteins: Two major group
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BIMM118 Main targets: Phospholipase
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BIMM118 Targets of cAMP: Protein Ki
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BIMM118 Cyclic Nucleotides • Guan
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BIMM118 Regulation of Receptors •
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BIMM118 Receptor Desensitization
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BIMM118 Nuclear Receptors • Lipid
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BIMM118 Phospholipids, Phosphoinosi
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BIMM118 Phospholipids, Phosphoinosi
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BIMM118 Phospholipids, Phosphoinosi
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BIMM118 • Eicosanoids: Arachidoni
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BIMM118 Arachidonic Acid Metabolism
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BIMM118 Growth Factor Receptors •
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BIMM118 Signaling through Adapter p
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BIMM118 Growth Factor Receptors
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BIMM118 Cytokine Receptors • Basi
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BIMM118 Signal Transduction: Cytoki
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BIMM118 Signal Transduction: SMADs:
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BIMM118 Autonomic Nervous System
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BIMM118 • Ganglia close to the in
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BIMM118 Receptors: • Cholinergic
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BIMM118 Cholinergic System - Agonis
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BIMM118 Cholinergic System - Agonis
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BIMM118 Cholinergic System - Agonis
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BIMM118 Cholinergic System - Agonis
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BIMM118 Cholinergic System - Antago
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BIMM118 Cholinergic System - Antago
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BIMM118 Cholinergic System - Antago
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BIMM118 Cholinergic System Parasymp
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BIMM118 • Ganglia close to the in
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BIMM118 Adrenergic System Terminati
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BIMM118 Sympathomimetics Adrenergic
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BIMM118 Sympathomimetics Indirect S
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BIMM118 Sympathomimetics α 1 - sel
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BIMM118 Sympathomimetics α 2 - sel
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BIMM118 Sympathomimetics β 1 - sel
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BIMM118 Sympatholytics α - selecti
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BIMM118 Sympatholytics Adrenergic S
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BIMM118 Sympatholytics Adrenergic S
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BIMM118 Cardiovascular Pharmacology
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BIMM118 Cardiac blood flow Cardiova
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BIMM118 Cardiovascular Pharmacology
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BIMM118 Venous return Cardiovascula
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BIMM118 Antihypertensive Drugs Four
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BIMM118 Antihypertensive Drugs: Vas
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BIMM118 Antihypertensive Drugs: RAA
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BIMM118 Antihypertensive Drugs: RAA
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BIMM118 Angina pectoris • Medical
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BIMM118 Angina pectoris - Nitrates
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BIMM118 Arrhythmias: Drug Classes:
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BIMM118 Arrhythmias: Class II - β-
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BIMM118 Congestive heart failure: C
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BIMM118 Congestive Heart Failure Tr
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BIMM118 Cardiac Glycosides: • Two
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BIMM118 Cardiac Glycosides: Congest
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BIMM118 Kidneys: Renal Pharmacology
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BIMM118 Renal Pharmacology • Bloo
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BIMM118 Diuretics: Renal Pharmacolo
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BIMM118 Diuretics: Thiazide diureti
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BIMM118 Diuretics: Potassium-sparin
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BIMM118 Renal Pharmacology
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BIMM118 Uricosuric agents: Renal Ph
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BIMM118 Acid production: • 2.5 L
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BIMM118 Antacids: Gastrointestinal
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BIMM118 Gastrointestinal Pharmacolo
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BIMM118 Gastrointestinal Pharmacolo
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BIMM118 Gastrointestinal Pharmacolo
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BIMM118 Laxatives: Gastrointestinal
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BIMM118 Gastrointestinal Pharmacolo
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BIMM118 Gastrointestinal Pharmacolo
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BIMM118 Gastrointestinal Pharmacolo
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BIMM118 Drugs for Metabolic Disorde
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BIMM118 Diabetes mellitus Blood glu
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BIMM118 Diabetes mellitus Insulin:
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BIMM118 Complications: • Short-te
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BIMM118 Insulin: Diabetes mellitus
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BIMM118 Insulin administration: Dia
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BIMM118 Diabetes mellitus Oral hypo
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BIMM118 Novel concepts: Alpha-Gluco
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BIMM118 Novel concepts (cont’d):
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BIMM118 Artherosclerosis: Hyperlipi
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BIMM118 Lipoprotein metabolism: - A
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BIMM118 Lipid-lowering drugs: Hyper
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BIMM118 Hyperlipidemia Lipid-loweri
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BIMM118 Lipid-lowering drugs: Bile
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BIMM118 Steroid-based Drugs • Adr
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BIMM118 Steroid hormone synthesis:
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BIMM118 Glucocorticoids (GC): Adren
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BIMM118 Adrenocortical Hormones Glu
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BIMM118 Glucocorticoids (GC): • P
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BIMM118 Glucocorticoids (GC): • A
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BIMM118 Sex Steroids • Female rep
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BIMM118 Sex Steroids • Female rep
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BIMM118 Sex Steroids Estrogens All
- Page 312 and 313:
BIMM118 Estrogens • Mestranol Sex
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BIMM118 Progesterons • Progestero
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BIMM118 Anti-Progesterons • Mifep
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BIMM118 Androgens Sex Steroids •
- Page 320 and 321:
BIMM118 Anabolic Androgens Sex Ster
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BIMM118 Anti-Androgens • Flutamid
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BIMM118 Oral Contraceptives • His
- Page 326 and 327:
BIMM118 Oral Contraceptives Sex Ste
- Page 328 and 329:
BIMM118 Oral Contraceptives Side ef
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BIMM118 Allergy Allergy: represents
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BIMM118 Allergy - Pathophysiology
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Allergy - Latex BIMM118 Latex: milk
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BIMM118 Allergy - Hymenoptera sting
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BIMM118 Allergy - Diagnosis
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BIMM118 Allergy - Histamine Recepto
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BIMM118 Allergy - Histamine Effects
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BIMM118 H1-Antagonists (“Antihist
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BIMM118 H1-Antagonists (“Antihist
- Page 348 and 349:
BIMM118 H1-Antagonists (“Antihist
- Page 350 and 351:
BIMM118 Allergy - Leukotrienes Leuk
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BIMM118 5-Lipoxygenase inhibitor:
- Page 354 and 355:
BIMM118 Neurotransmitters in the CN
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BIMM118 Drugs Targeting the CNS GAB
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BIMM118 Drugs Targeting the CNS 5-H
- Page 360 and 361:
BIMM118 Anxiety: Drugs Targeting th
- Page 362 and 363:
BIMM118 Hypnotics / Anxiolytics Bar
- Page 364 and 365:
BIMM118 Benzodiazepines Hypnotics /
- Page 366 and 367:
BIMM118 MAO Inhibitors: Antidepress
- Page 368 and 369:
BIMM118 Antidepressants Selective S
- Page 370 and 371:
BIMM118 Classical neuroleptics: Phe
- Page 372 and 373:
BIMM118 Atypical neuroleptics: - In
- Page 374 and 375:
BIMM118 Pathology: Parkinson’s Di
- Page 376 and 377:
BIMM118 Dopamine agonists: Parkinso
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BIMM118 Epilepsy Treatment strategi
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BIMM118 Glycine receptor antagonist
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BIMM118 • Alcoholism - Long-term
- Page 384 and 385:
BIMM118 Drugs against Pain • Anes
- Page 386 and 387:
BIMM118 General Anesthetics Inhalat
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BIMM118 General Anesthetics Inhalat
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BIMM118 General Anesthetics Modern
- Page 392 and 393:
BIMM118 Opioid Analgesics Opiates:
- Page 394 and 395:
BIMM118 Opiates: Morphine: - CNS: -
- Page 396 and 397:
BIMM118 Heroin (diamorphine): - Dia
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BIMM118 Opiate antagonists: • Nal
- Page 400 and 401:
BIMM118 Mode of action: Local Anest
- Page 402 and 403:
BIMM118 Classification: • Cocaine
- Page 404 and 405:
BIMM118 NSAIDs Non-Steroidal Anti-I
- Page 406 and 407:
BIMM118 NSAIDs Non-Steroidal Anti-I
- Page 408 and 409:
BIMM118 COX-2 specific NSAIDs: •
- Page 410 and 411:
BIMM118 General Aspects: Antibiotic
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BIMM118 • Resistance avoided/dela
- Page 414 and 415:
BIMM118 Antibiotics - Cell wall syn
- Page 416 and 417:
BIMM118 Penicillins Antibiotics - C
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BIMM118 Antibiotics - Cell wall syn
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BIMM118 Antibiotics - Cell wall syn
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BIMM118 Antibiotics - Cell wall syn
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BIMM118 Antibiotics - Cell wall syn
- Page 426 and 427:
BIMM118 Antibiotics - Protein synth
- Page 428 and 429:
BIMM118 Antibiotics - Protein synth
- Page 430 and 431:
BIMM118 Macrolides Antibiotics - Pr
- Page 432 and 433:
BIMM118 Folate antagonists Antibiot
- Page 434 and 435:
BIMM118 Trimethoprim Antibiotics -
- Page 436 and 437:
BIMM118 Quinolones • Nalidixic ac
- Page 438 and 439:
BIMM118 Chemotherapeutic Agents •
- Page 440 and 441:
BIMM118 Fungal Growth Patterns •
- Page 442 and 443:
BIMM118 Mycosis • Fungal infectio
- Page 444 and 445:
BIMM118 Cutaneous Mycosis - Also kn
- Page 446 and 447:
BIMM118 • Tinea pedis - Classical
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BIMM118 Systemic Mycosis - Infectio
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BIMM118 Systemic Mycosis • Blasto
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BIMM118 Opportunistic Mycosis • C
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BIMM118 Opportunistic Mycosis • C
- Page 456 and 457:
BIMM118 Polyenes (Amphotericin, Nys
- Page 458 and 459:
BIMM118 Antifungal Drugs - Azoles A
- Page 460 and 461:
BIMM118 Imidazoles • Miconazole -
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BIMM118 Antifungal Drugs - Antimeta
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BIMM118 Antifungal Drugs - Echinoca
- Page 466:
BIMM118 Antifungals - Summary
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