Antibiotic prophylaxis in surgery. (SIGN Guideline No 104)
Antibiotic prophylaxis in surgery. (SIGN Guideline No 104)
Antibiotic prophylaxis in surgery. (SIGN Guideline No 104)
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<strong>Antibiotic</strong> prophylAxis <strong>in</strong> <strong>surgery</strong><br />
16<br />
Operation Recommendation Odds Ratio NNT Outcome Evidence level<br />
heAD AnD necK<br />
ear, nose and throat - benign<br />
0.46 13 otorrhea 1 ++ ,1 + ,2 ++80-82<br />
<strong>Antibiotic</strong> <strong>prophylaxis</strong> (a s<strong>in</strong>gle dose of topical antibiotic)<br />
is recommended<br />
grommet <strong>in</strong>sertion b<br />
head and neck<br />
83, 84<br />
D <strong>Antibiotic</strong> <strong>prophylaxis</strong> is not recommended 4<br />
head and neck <strong>surgery</strong><br />
(clean, benign)<br />
+85, 86<br />
Wound <strong>in</strong>fection 2<br />
-29<br />
9<br />
c <strong>Antibiotic</strong> <strong>prophylaxis</strong> should be considered 1.28<br />
0.12<br />
head and neck <strong>surgery</strong><br />
(clean, malignant; neck<br />
dissection)<br />
A <strong>Antibiotic</strong> <strong>prophylaxis</strong> is recommended 0.37 6 Wound <strong>in</strong>fection 1 ++87-90<br />
+54, 85 2<br />
The duration of prophylactic antibiotics should not be<br />
more than 24 hours<br />
c<br />
head and neck <strong>surgery</strong><br />
(contam<strong>in</strong>ated/cleancontam<strong>in</strong>ated)<br />
4 84<br />
Ensure broad spectrum antimicrobial cover for aerobic<br />
and anaerobic organisms<br />
D
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