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Kalabhavi Srinivas K.pdf

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2. Extrinsic causes:<br />

Proforma<br />

An aberrant, accessory, or early branching lower pole vessel is the most<br />

common cause of extrinsic UPJ obstruction. This is a major case of UPJ obstruction<br />

in adults.<br />

These vessels pass anteriorly to the UPJ or proximal ureter and contribute to<br />

mechanical obstruction. Nixon (1953) reported that 25 of 78 cases of UPJ<br />

obstruction were secondary to vascular compression. Other reported incidences have<br />

varied between 15% and 52% (Ericsson et al, 1961; Williams and Kenawi, 1976,<br />

Johnson et al, 1977; Stephens, 1982; Lowe and Marshall, 1984). Whether the<br />

aberrant vessel causes obstruction or is a co-variable that exists along with an<br />

intrinsic narrowing is unclear.<br />

Stephens (1982) theorized that when an aberrant or accessory renal artery to<br />

the lower pole of the kidney is present and the ureter courses behind it, the ureter may<br />

angulate at both the UPJ and the point at which it traverses over the vessel as the<br />

pelvis fills and bulges inferiorly. Further angulations of the ureter occurs as it<br />

becomes adherent to the UPJ secondary to an inflammatory process. A two-point<br />

obstruction ensues, with kinking of the ureter at the UPJ and at the point where the<br />

ureter drapes over the vessel. Stephens (1982) could find no evidence of stricture or<br />

fibrosis at these points when the ureter was freed of its adhesions and lifted off the<br />

vessel. However, he suggested that over time, these areas may become ischemic,<br />

fibrotic, and finally stenotic 16 .

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