ICDs and CRTs for Dummies

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Cardiac Dyssynchrony Effects of Abnormal Activation Sequences • atrioventricular asynchrony • negative LA - LV: LA contraction against closed MV • long LA - LV: late diastolic MR decreases LV filling time • interventricular asynchrony • decreased LV filling time • septum recruited to RV ejection • intraventricular asynchrony • some LV contraction before aortic valve opening • some LV contraction after aortic valve closure • wasted work stretching noncontracting regions • uncoordinated papillary muscles leads to MR • decreased diastolic LV filling time • intramural asynchrony • contraction is non-transmural
STUDY N RR MUSTIC SR 58 3.00 (0.13 – 70.7) MUSTIC AF 43 2.19 (0.09 – 50.9) MIRACLE 453 0.74 (0.36 – 1.53) COMPANION 925 0.85 (0.66 – 1.09) CARE HF 813 0.67 (0.53 – 0.86) All Trials 2292 0.76 (0.64 – 0.90) RAFT Investigators ICDs and CRTs for Dummies All-Cause Mortality – CRT vs Control Class III/IV Pts 0.2 0.4 0.6 0.8 1.0 1.2 1.4 1.6 RELATIVE RISK
Page 1 and 2: Disclosures - L. Brent Mitchell, MD
Page 3 and 4: ICDs and CRTs for Dummies Available
Page 5 and 6: ICDs and CRTs for Dummies
Page 7 and 8: ICDs and CRTs for Dummies Sudden Ca
Page 9 and 10: ICDs and CRTs for Dummies All-Cause
Page 11 and 12: ICDs and CRTs for Dummies Sudden Ca
Page 15: ICDs and CRTs for Dummies Available
Page 19 and 20: ICDs and CRTs for Dummies Who Shoul
Page 21 and 22: ICDs and CRTs for Dummies All-Cause
Page 23 and 24: STUDY N RR MIRACLE ICD II 186 1.19
Page 27 and 28: Multicentre Automatic Defibrillator
Page 29 and 30: Resynchronization in Ambulatory Hea
Page 31 and 32: Cumulative Incidence Resynchronizat
Page 33 and 34: ICDs and CRTs for Dummies Who Shoul
Page 35: When? ICDs and CRTs for Dummies “
Page 38 and 39: ICD Implantation ACC/AHA/HRS (2008)
Page 40 and 41: ICD Implantation CCS Consensus (200
Page 42 and 43: ICD Implantation CCS Consensus (200

ICDs and CRTs for Dummies

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