(Converted)-4 - Journal of Cell and Molecular Biology - Haliç ...

42 Zerrin Y›lmaz et al.
repetitive regions that are located on the centromeres
of chromosomes 1, 9, and 16 and on the distal arm of
Y chromosome (Burkholder and Duczek, 1980; Cook,
1995). Our AFM image also helps us to understand
that these regions were not belonging to G- banding
regions, as there was not a banding pattern (Tan et al.,
2001).
AFM can be considered as a novel technique for
analysing detailed structures of chromosomes for its
line measure analysis and 3-D image capture
capabilities. Reflecting these capabilities, AFM helped
us to investigate the gap region on the derivative
chromosome and this study is also novel by making
new implementations on the mechanism of
translocation. As a conclusion, the capability of AFM
for detecting chromosomal abnormalities will reflect
light into further studies.
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