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endocrine toxicology - Ecology and Evolutionary Biology - Texas ...

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Grading<br />

Study<br />

Materials:<br />

Exam-3: Multiple Choice type: 20%<br />

Exam-4: Case study report *: 40%<br />

Total: 100%<br />

* Case Study Report: All students will be required<br />

to prepare a case study report (maximum total of<br />

10 pages, 2.0 line spaced; 1 inch margins; 12 pt<br />

Arial or Times Roman font; 10 references<br />

minimum). The case study will require examining a<br />

chemical in a specific contaminated site (e.g.,<br />

chromium in California <strong>and</strong> New Jersey) or a<br />

chemical that affects a more specific target<br />

<strong>endocrine</strong> organ (e.g., organochlorine <strong>and</strong> thyroid<br />

gl<strong>and</strong> or dioxin <strong>and</strong> endometriosis), or choose one<br />

of the “World’s worst polluted places”, <strong>and</strong> select<br />

one particular EDC <strong>and</strong> its clinical /endocrinological<br />

relevance on the health of the people living in that<br />

environment. Alternatively, choose an EDC that is<br />

more relevant to occupational exposure etc., (the<br />

student can obtain help from the instructor to<br />

choose the topic). The case study will examine<br />

sources, pathways, transport, levels of<br />

contamination in the environment, remediation<br />

process (if any), <strong>and</strong> receptors in the target<br />

<strong>endocrine</strong> organ, <strong>and</strong> end-point diseases or<br />

disorders. The paper should be submitted<br />

according to a required format <strong>and</strong> will reference<br />

peer‐reviewed work <strong>and</strong> reviews, website<br />

information, reports from USEPA <strong>and</strong>/or ATSDR,<br />

The Blacksmith Institute etc.<br />

90-100 : A<br />

80-89.99 : B<br />

70-79.99 : C<br />

60-69.99 : D<br />

Less than 60 : F<br />

H<strong>and</strong> out of the lecture will be given (Most of the<br />

objective questions will be taken from lectures).<br />

Particular book chapters or interested journals<br />

could be referred.<br />

Course material will be derived from the<br />

following books & reviews.<br />

1. Casarett & Doull's Essentials of Toxicology, by<br />

Curtis D. Klaassen <strong>and</strong> John B. Watkins III.<br />

2. Endocrine Toxicology, Third Edition, by J.<br />

Charles Eldridge <strong>and</strong> James T. Stevens.<br />

3. Our Stolen Future by<br />

Theo Colborn, Dianne Dumanoski, John Peterson<br />

Myers, published by Dutton.<br />

4. Environmental Endocrine Disrupters: An<br />

<strong>Evolutionary</strong> Perspective, by A Crain, L J Guillette<br />

Jr., published by Taylor & Francis.<br />

5. Endocrine Disrupting Chemicals: An Endocrine<br />

Exam-3:Multiple Choice type: 20%<br />

Exam-4:Descriptive (short essays)* 40%<br />

Total: 100%<br />

Students will be asked essay<br />

questions, <strong>and</strong> should be answered in<br />

the given page limit. Exams 1, 2 & 3<br />

are class room exams <strong>and</strong> exam 4 is a<br />

take home assignment.<br />

Case study report not required.<br />

90-100 : A<br />

80-89.99 : B<br />

70-79.99 : C<br />

60-69.99 : D<br />

Less than 60 : F<br />

H<strong>and</strong> out of the lecture will be given (most<br />

of the questions will be taken from<br />

lectures). Particular book chapters or<br />

interested journals could be referred.<br />

Course material will be derived from<br />

the following books & reviews.<br />

1. Casarett & Doull's Essentials of<br />

Toxicology, by Curtis D. Klaassen <strong>and</strong><br />

John B. Watkins III.<br />

2. Endocrine Toxicology, Third Edition, by<br />

J. Charles Eldridge <strong>and</strong> James T.<br />

Stevens.<br />

3. Our Stolen Future by<br />

Theo Colborn, Dianne Dumanoski, John<br />

Peterson Myers, published by Dutton.<br />

4. Environmental Endocrine Disrupters:

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