Analytical solutions from a single source - Aqura Gmbh

Analytical solutions
from a single source

Techniques & procedures
04 - 05 Quality standard
Development priorities
06 - 07 Inorganic analytics
Chromatography
08 - 09 Computational Chemistry
Mass spectrometry
10 - 11 Microscopy
Molecular spectroscopy
12 - 13 Surface and interface analytics
Organic analytics
14 - 15 Physical substance data
Biochemical analytics
16 -17 Safety testing
Environmental measuring methods
18 - 19 Management team
Certifications
“Thank you for the very good
cooperation and helpful
discussions.”
“I thank you for the
unsurpassed fine cooperation
with you; not only for your
professionality but also for the
kindness and the collegiality ...”
Customer satisfaction analysis 2010
What do you expect from a company which provides
analytical services with the greatest of care and
precision?
For example the ability to use a wide variety
of methods? Always being one step ahead
of the competition? Certainly a corporate
culture which is based on a permanent dialogue
and working together as partners, as
well as an experienced and motivated team
which solves all problems with farsightedness
and expertise.
With our techniques and methods we have
been serving many sectors for years. Our
attention is strongly focused on the fields of
chemistry, pharmaceutics, biotechnology
and materials science. The analyses perfor-
med by us, their results and the information
obtained from them are of course treated
confidentially.
Range of services
In our laboratories we offer analytical services
in the fields of research, process development,
product development, application
technology, production and plant safety.
The basis for this is a wide range of modern
methods and techniques, as well as a large
number of validated procedures which we
have developed ourselves.
We are specialists in the following sectors:
• Special chemistry
• Pharmaceutical industry and
biotechnology
• Materials science
02 - 03

Quality standard
Experience
Sometimes it seems to us that the world
turns a little faster every day. For industrial
companies it is true more than ever that the
time available for making accurate decisions
with far-reaching consequences is becoming
shorter and shorter.
In this situation, it is a relief to have a reliable
and experienced partner at one’s side who
perfectly knows his trade and can really help.
Development priorities
Aims
Our priorities include developing, evaluating
and testing new analytical methods on
large scale equipment and special analytical
techniques.
The aim is to make the necessary methods
available and utilisable at an early stage
through systematic transfer of knowledge.
Here, the main focus is on a greater degree
of selectivity and detection sensitivity,
greater speed and – to a certain extent –
completely new interpretation possibilities.
Quality
Our testing institute guarantees a high
level of quality for all analyses. Our quality
standards have been recognised by various
independent bodies.
Regular participation in round robin tests
is as self-evident for us as the continual
checks of our methods.
Confidentiality
It goes without saying that the analyses
performed by us, their results and the
information obtained in this connection
are treated confidentially.
Upon request additional confidentiality
agreements can be concluded.
Examples
• Development of new tools and
applications from computational
chemistry / molecular modelling
• Modern electron microscopic and
spectroscopic processes for charac-
terising surfaces (e.g. scanning probe
methods, molecule detection down
to the ppb range)
• New mass spectrometric techniques
and coupling techniques for high
throughput and bioanalytics to
supplement high-throughput
screening, proteome research and
biocatalytic developments
Processing time
We guarantee the fastest possible processing
of the samples around the clock, according to
schedule and in line with your requirements.
Depending on the type of technique
employed, this may also be possible within
one day.
Services
Our services are extensive and highly
specialised. For particularly urgent cases,
we offer an express service and sample
collection service.
We come to you, fetch and return the
samples. Reliably and fast.
“AQura stands out due to
their high scientific level and
excellent experts ...”
“ ... what should be emphasised
is the sustainability of their
customer care before, while and
following the actual order ...”
Customer satisfaction analysis 2010
04 - 05

Inorganic analytics
Qualitative and quantitative element
determination in the total sample
• AAS: Flame, graphite furnace, hydride
generation, cold vapour atomic absorption
spectroscopy
• ICP-OES: Optical emission spectroscopy
with inductively coupled plasma
• ICP-MS: Elemental mass spectrometry
with inductively coupled plasma, high
and low resolution, ultra-trace analysis,
individual element and screening analysis,
CE, LC-ICP-MS coupling
• GD-MS: Multi-element analysis,
elemental survey analysis
• XRF: X-ray fluorescence analysis,
quantitative and qualitative individual
elements, qualitative overview analysis,
semi-quantitative XRF with fundamental
parameter evaluation
• Volumetry, gravimetry, electrogravimetry
• Photometry
Chromatography
Gas chromatography
(GC)
• Various detectors such as flame ionisation,
thermal conductivity, mass spectrometry,
photometry, electron capture, etc.
• Various injection techniques such as oncolumn,
cold injection, thermodesorption,
etc.
• Gases and liquefied gases
• Gas samples, also under GMP
• Pressure gas analytics for the pharmaceutical
industry (identity, composition,
oil traces, particle content)
• GC after derivatisation
• From the headspace
(headspace GC, purge & trap GC / MS)
• High-temperature GC
• Separation of enantiomers
• Pyrolysis GC / MS
• Titrations (complexometric, acid / base,
potentiometric, redox, argentometric)
• Ion-sensitive electrodes
• Ion-chromatography, quantitative deter-
mination of halides, anions and cations
• Combustion analyses,
elemental analyses in inorganics
(determination of C, H, N, O and S)
• Ash determinations,
ignition and drying losses
High-performance liquid
chromatography (HPLC)
• Various separation selectivities such as
reversed phase, normal phase, ion exclusion,
ion pair chromatography, etc.
• Various detectors such as UV, diode array,
fluorescence, refractive index, mass
spectrometry, conductivity, light diffusion,
nitrogen-selective, etc.
• Pre-column and post-column derivatisation
• Separation of enantiomers, analytical
racemate separation, determination of
enantiomeric purity
• Preparative isolation of pure enantiomers
Elements on surfaces and
in thin layers
• GD-MS: Glow discharge mass spectrometry
• Surface analytics, microscopy, X-ray micro-
analysis (EDX)
XRD crystalline phase analysis
• XRD: Qualitative and quantitative phase
analysis
• X-ray crystallite size determination
• Determination of lattice parameters
• Texture determination (statement on
textures / preferred orientations)
• Rietveld refinement
(structural methods, quantitative analysis)
• Polymorph determination
• Small-angle scattering (SAXS) for the
determination of primary particle sizes
• Micro-preparative and preparative
isolation of unknown secondary
components from products or product
blends (identification, purification,
characterisation of reference material)
• ASA, amino acid analysis, qualitative and
quantitative amino acid determination,
trace determinations, amino acid analytics
after hydrolysis (e.g. for peptide
quantification and characterisation)
Gel permeation chromatography
(GPC)
• GPC with RI and UV detection
• Absolute molar mass and molar mass
distribution according to gel chromatography
and MALS detection
• Molar mass fractions, preparative
isolation, oligomer and polymer content
determination in organic monomers and
pharmaceutical active substances
Ion chromatography
(IC)
• Determination of inorganic and / or
organic anions and cations (including
carbohydrate analytics)
• Besides the standard forms of detection
in HPLC, conductivity detection (with
and without suppression techniques)
and electrochemical detection are used
Capillary electrophoresis
(CE)
• Direct and indirect UV detection, diode
array
• Capillary zone electrophoresis (CZE) and
micellar electrokinetic chromatography
(MEKC)
• Separation of enantiomers
• Isotachophoresis
Info
In chromatography, the selective analysis
of individual components in a mixture is
performed through the physical separation
of the individual components.
Thin-layer chromatography
(TLC)
• Qualitative, semi-quantitative and
quantitative determination of purity,
main and secondary components
• Preparative separation, semi-quantitative
and quantitative determination of
enantiomeric purity
• Preparative separation of substances or
substance blends, pure isolation of
secondary components from product
blends
Element speciation
• Photometry
• HPLC-ICP-MS coupling
06 - 07

Computational chemistry
Molecular simulation (quantum chemistry,
force fields and statistical methods)
• Molecular and crystalline structures
• Crystal morphology
• Chemical reactions, catalysis,
surface processes
• Substance data
• Polymer characteristics
• Structure-property relationships
• Reaction kinetics, molecular dynamics
• Phase equilibria
• Solubility
Mass spectrometry
General mass spectrometry
• Ionisation techniques: Electron impact (EI),
chemical ionisation (CI), electrospray (ESI),
nano-ESI, atmospheric pressure chemical
ionisation (APCI)
• Positive and negative ions
• Low-resolution analysers (ion traps,
quadropole, time-of-flight)
• High Mass resolution with Fourier-transform
ion cyclotron resonance mass spectrometry
(FT-ICR) and orbitrap technology
• Multi-dimensional mass spectrometry
(MS-MS, MSn)
• Accurate masses for determining elemental
composition / empirical formula
Coupling techniques
• Direct evaporation
• Coupling with gas chromatography (GC)
• Static/dynamic headspace GC-MS
(HS-GC-MS)
• Thermodesorption GC-MS (TD-GC-MS)
• Pyrolysis GC-MS
• Liquid chromatography (HPLC,
micro-HPLC, nano-HPLC, UPLC)
• Ion chromatography (IC-MS)
• Gel permeation / size exclusion
chromatography (GPC/SEC-MS)
• HPLC ICP MS for elemental speciation
Info
Mass spectrometry enables the identification
and quantification of individual components
in complex substance mixtures. The high
level of detection sensitivity allows statements
to be made at trace concentration level.
Quality problems with products are clarified at
the molecular level with mass spectrometry.
Special techniques
Info
• MALDI-TOF-MS
Wir nutzen bei spektroskopischen
• Analysis of technical polymers and
Struktur-Untersuchungen umfangreiche
biopolymers
Datenbanken.
• Qualitative and quantitative proteomics
Zur Strukturaufklärung und Identitätsprüfung
• Enzymatic führen digestion wir auch analytics kombinierte Arbeiten
mit spektroskopischen
• Identity and purity tests of proteins
Methoden (NMR, IR, Raman, UV etc.) nach
Reindarstellung • High-throughput von screening Substanzen (HTS) mit der
präparativen
• High-throughput
HPLC oder
quantification
GC durch.
with
SRM techniques
• LC-MS on chiral phases
• LC-MS with N-selective
chemiluminescence detector
08 - 09

Microscopy
Electron microscopy
• Scanning electron microscopy (SEM) and
field emission scanning electron microscopy
(FE-SEM) with various sample preparation
techniques, including (cryo-) microtomy,
embedding, grinding, polishing, cryofracture,
selective etching
• Transmission electron microscopy (TEM)
with various sample preparation techniques,
including (cryo-) ultra-microtomy,
contrasting methods
• Energy dispersive X-ray analysis (EDX)
in SEM (microanalysis) and TEM
(nanoanalysis)
• Electron energy loss spectroscopy (EELS)
in the TEM
• Cryo-TEM
Molecular spectroscopy
NMR spectroscopy
• Digital 400, 500 and 600 MHz NMR
spectrometer
• From 2012: Cryo probe technology for
maximum sensivity of 1 H and hetero nuclei
• Routine 1 H, 13 C, 29 Si and 31 P-NMR
spectroscopy
• Also other NMR-active hetero nuclei
( 11 B, 27 Al, 119 Sn, 195 Pt, amongst others)
• Determination of molecular structure and
identity
• Special pulse techniques, multi-dimensional
NMR for structural elucidation
• Content determination against certified
internal standards (qNMR)
• Measurements in accordance with GMP
and GLP requirements on qualified
spectrometers
• Kinetic measurements, molecular dynamics
• Solid state NMR (400 MHz), CP-MAS
• Analytical TEM with maximum resolution
(HR-TEM, 200 kV field emission, resolution
down to 1.2 Angstrom), with STEM addition
and HAADF detector
• Electron diffraction, determination of
lattice constants
• Particle size distributions
• Primary particle size determination
(according to ASTM, using TGZ techniques)
• Aggregate size distributions and
classification analyses
• Plasma preparation techniques
• Digital image processing and
documentation
Optical microscopy
• Optical microscopy (reflected/transmitted
light, polarisation, hot stage, fluorescence)
• Digital image processing and
documentation
• Laser-assisted surface profiling
(2 and 3-D measurements)
Infrared / Near-infrared spectroscopy
(IR / NIR), Raman spectroscopy
• Fourier transform infrared spectroscopy
(FT-IR)
• Measurements in accordance with GMP
and GLP requirements on qualified
spectrometers
• Surface and micro-particle analysis with
attenuated total reflection (ATR, diamond
ATR, germanium ATR)
• Reflection measurements with heatable
DRIFT unit
• Identity check using NIR spectroscopy
• FT Raman spectroscopy with NIR excitation
Spectroscopy in the ultraviolet and
visible range (UV / Vis)
• UV / Vis spectrometer scaning and
diode array
• UV / Vis remission measurements
(reflection of powders and surfaces up
to 1100 nm) UV/Vis applications with or
without derivatisation, colour reactions
and derivative spectroscopy
• Spectroscopic determination of colour
numbers (APHA, Gardner, yellowness
index) etc.
Info
On the basis of their spectroscopic properties,
molecules can be identified in a similar
manner to a fingerprint.
If unknown compounds such as undesirable
impurities occur, the molecular structure
is often determined by means of detective
work using spectroscopy.
In addition, the purity and the course of
entire chemical reactions can be followed.
10 -11

Surface, interface and
depth profile analyses
Solid matter surface analyses
• X-ray photoelectron spectroscopy
(XPS) / electron spectroscopy for chemical
analysis (ESCA), monochromatised and
non-monochromatised X-rays
• Localised small spot XPS
• Chemical XPS surface mapping, parallel
imaging
• XPS for determining the electrostatics of
powders
• Cryo-XPS
• Ultraviolet photoelectron spectroscopy
(UPS)
• Residual gas and desorption mass
spectrometry
• In-situ reduction and / or temperature
pre-treatment
Organic analytics
Chemical characteristics
• Pharmacopoeial test
(DAB, USP, BP, Ph.Eur., Ph. Helv., etc. )
• Bromine, iodine, carbonyl, ester, hydroxyl,
acid, base, saponification numbers
• Epoxide, NCO, peroxide content
• Determinations of water content
(in solid, liquid, gaseous samples)
• Residue of evaporation, residual moisture,
dry and extract content
• Ash, volatility
• Pour point
• Colour numbers, colorimetry, photometry
(APHA, Gardner, Sayboldt, iodine, etc.)
• Polarimetry (polarimeter, microcells,
also heatable)
• Secondary ion mass spectrometry
(SIMS), static and dynamic
• Secondary neutral particle mass
spectrometry (SNMS)
• Ion scattering spectroscopy (ISS)
• Depth profile analyses by means of XPS
and SIMS
• Laser-assisted surface profilometer (2D
and 3D measurements)
Atomic force microscopy (AFM)
• Determination of the surface roughness,
contact mode, non-contact mode,
tapping mode, phase contrast mode,
nano-indentation
Wet analyses, titrations
• Neutralisation, precipitation and redox
titrations, complexometry, potentiometry
• Titration in non-aqueous media
• Two-phase titration for surfactants
• Water determination according to
Karl-Fischer (coulometric and volumetric
and oven technique)
Characteristics of polymers
• Carboxyl, amino, hydroxyl terminal group
assay
• Gel fraction, carbon black content, filler
content
• J-value, intrinsic viscosity, solution viscosity
• Molar mass (relative), molar mass
distribution
• Water solubility
• Residual monomers
• Emissions
• Polymer composition
Photometry, UV/VIS spectroscopy
• Anions, cations, stabilisers, aldehydes,
phenols, tensides
• Turbidity measurements, nephelometry
• Spectroscopic determination of colour
numbers (APHA, Gardner, yellowness
index, etc.)
• UV / Vis applications with / without
derivatisation, colour reactions and
derivative spectroscopy
• UV / Vis spectrometer (recording and
diode array), transmission and reflection
measurements
• Fluorescence spectroscopy
Sorption analysis and porosimetry
• Specific surface area (BET, STSA)
• Fractal dimension (FHH, BET)
• Analysis of micro- and mesopores by
gas adsorption (micropores: t-plot,
Horvath-Kavazoe, DFT / mesopores: BJH)
• Mercury porosimetry
• Determination of metal dispersion by gas
chemisorption measurements (Pt, Pd, Rh,
Ni, Cu, …)
• Temperature-programmed desorption /
reduction / oxidation (TPD / TPR / TPO)
• Water vapour sorption (DVS)
Combustion and elemental analyses
• C/H/N/S/O determination
• Oxygen determination in the high
temperature furnace, also in metal / semimetal
oxides and samples containing
fluorine or phosphorus
• Total sulphur, fluorine, chlorine, bromine,
iodine by Wickbold digestion
• Total inorganic carbon (TIC)
• Organic carbon (TOC, DOC)
• Total carbon (TC)
• Total nitrogen and ammonium-nitrogen
by Kjeldahl analysis
Tensiometry and contact angle
• Surface and interfacial tension of liquids
(ring, plate, pending-drop, spinning
drop methods)
• Critical micelle concentration (CMC)
• Contact angle (sessile drop),
surface energies
• Wettability/wetting effect on planar
surfaces, fibres, powders
Zeta potential
• Zeta potential
(electrophoretic light scattering,
electroacoustics), titration curves
Electrochemical procedures
• Amperometry, dead-stop titrations
• Conductometry, coulometry
• Potentiometry
(mass analyses, micro-pH)
• Voltammetry, polarography
Info
Applying analytical techniques a balance
for the chemical elements and functional
groups can be drawn.
Through combination with higher selective
analytical procedures (separation methods,
spectroscopy) it is possible to achieve a fundamental
understanding of the composition
of products on an organic chemical basis.
12 -13

Physical substance data
Particle size distribution
• Laser diffraction spectroscopy
(wet, dry dispersion)
• Dynamic light scattering (DLS)
• Single particle optical sizing
• Sieve analysis (dry, wet, air jet sieving)
• Dynamic image analysis
Thermal analyses and calorimetry
• Thermogravimetry (TG, thermal stability)
• Differential scanning calorimetry (DSC)
• Simultaneous thermal analysis (TG / DSC)
• Simultaneous thermal analysis with evolved
gas analysis (EGA) by coupling with mass
spectro metry and infrared spectrometry
(TG / DTA-MS-FTIR)
• Temperature programmed desorption /
reduction / oxidation (TPD / TPR / TPO)
• Isothermal reaction calorimetry
Biochemical analytics
Gel electrophoresis
• Isoelectric focussing (IEF)
• SDS-page, 2D gel electrophoresis with
different staining techniques and image
analysis
• Western blot for protein with specific
antibody detection
Enzyme immunoassays
• ELISA techniques
“Bio-specific” NMR and MS Methods
• Proteomics
• Sequence analyses on polypeptides /
proteins
• Quantitative and qualitative metabolomics
Protein and DNA analytics
• Capillary electrophoresis
• Protein determination according to
Bradford (colorimetric)
• Protein digestion
• Endotoxin determination (LAL test)
• Fluorometric double-stranded (ds) DNA
determination
Field-flow fractionation
• Characterisation of biopolymers, determination
of mean molecular weights,
radii of gyration
Electrical properties
• Surface and volume resistivitiy
(films, plates, layers)
• Dielectric constant, permittivity
(liquids, films)
• Breakdown voltage
• Conductivity (aqueous solutions)
Rheology and viscosity
• Rotation and oscillation measurements
(flow curves, yield point, viscoelastic
behaviour, structure)
• Capillary viscosimetry
• Viscosity index, K value,
molecular weight determination
Physical and other characteristics
• Density (liquids: pycnometer, oscillating
densimeter; solids: pycnometer,
gas pycnometer, buoyancy method)
• Bulk density, tapped densitiy
• Powder flowability
(angle of repose, flow index, Hausner ratio)
• Melting point
(capillary method, DSC, hot stage
microscope)
• Freezing point
• Pour point, cloud point
• Boiling point (ebulliometer, DSC)
• Distillation range
• Vapour pressure
(static, dynamic method, vapour pressure
balance)
• Solubility measurements
• Surface tension
• Refractive index
• Thermal conductivity (solids, powders,
liquids)
• Specific heat
• Calorific value, heating value
• Water activity (Aw),
water vapour sorption (DVS)
• Zeta potential of dispersions
• Permeability of films / glove testing
• Particulate contamination
• Air-release/water separability of oils
• Oxidation stability of oils
Info
Physical measurements provide essential
information for the characterisation of
substances and materials.
Both in the development of products with
high-quality application technology properties
and in the design, optimisation and monitoring
of production processes, know-ledge of
the physical material data is essential as the
key to a deeper understanding of the material
properties.
14 -15

Safety testing
Classification of hazardous substances
(REACH, GHS) in physical hazard classes
• Explosives
• Self-reactive substances
• Self-heating substances
• Oxidising substances
• Flammable substances
(gases, liquids, solids)
Environmental measuring methods
Emission measurements
• Nitrogen oxides
• Sulphur dioxide, sulphur trioxide
• Carbon oxides
• Hydrogen halides, chlorine
• Ammonia, hydrazine, HCN
• Oxygen, hydrogen, nitrogen
• Methane
• Dust and dust components
• Organic compounds
• Solvents
• PAH
• Particle size distribution
Transport Classification
(hazardous goods ADR, RID, UN, IMDG)
• Class 3
(flammable liquids)
• Class 4.1
(combustible solids)
• Class 4.1
(self-reactive substances, “UN Flow Chart“,
“SADT“, also detonation tests)
• Class 4.2
(self-heating substances)
• Class 4.3
(substances forming flammable gases
upon contact with water)
• Class 5.1
(oxidising substances, solids and
liquids)
• Class 5.2
(organic peroxides, “UN Flow Chart“,
“SADT“, also detonation tests)
Workplace and room air measurements
Accredited according to
DIN EN ISO / IEC 17025:2005
• Aerosols, dusts, dust components
• Inorganic and organic gases and vapours
• Particle measurements in clean rooms
• Particle size distribution
• Fine dust
• Nanoparticles
• Diesel engine emissions (DME)
• Asbestos
• Solvents, VOC
• Work area analyses
Combustibility, flammability, explosion
properties of dusts (VDI Directive)
• Combustibility class, smouldering temperature,
flammability, low-temperature
carbonisation gas formation of dust layers
• Auto-ignition of dust layers
• Volume-dependency of auto-ignition
• Explosiveness of dispersed dusts
• Explosion characteristics of dispersed dusts
(explosion limits, Pmax, KSt value), 20-liter
sphere, 1 cubic metre container
• Limiting oxygen concentration of
dispersed dusts ( “inerting”)
• Ignition temperature and minimum
ignition energy of dispersed dusts
Flammability, explosion properties of
liquids, gases and vapours (DIN, EN)
• Flashpoint, ignition temperature,
sustained combustibility
• Explosion limits
(also under process conditions: pressure
and temperature dependency)
• Explosion points (temperature values
corresponding to the explosion limits,
lower explosion point = equilibrium
flashpoint)
• Limiting oxygen concentration
• Explosion characteristics
(explosion pressure, KG value)
• Explosion ranges of multicomponent
systems (also under process conditions)
• Detonation ability of gases and vapours
( “detonation tube”, also under process
conditions)
• Flashback / explosion suppression under
process conditions
Thermal stability of substances and
mixtures (data for storage and plant safety)
• Differential scanning calorimetry (DSC)
• Adiabatic warm storage
(kinetics of exothermal reactions)
• SADT for various containers and
package sizes
• Adiabatic induction time (TMRad)
• Reaction calorimetry
(heat production rate, reaction enthalpy,
reactant accumulation)
Properties of critical reactions
• Isothermal and isoperibol reaction
calorimetry (in particular pressure
reactions, equipment: Mettler RC1 and
Setaram C80)
• Adiabatic reaction calorimetry (runaway
reactions, equipment: VSP and PHI TEC II)
• Adiabatic tests for emergency relief of
reactors, storage tanks, rail tank cars, etc.
Info
Aim
Design of bursting discs and safety valves,
also for two-phase flow (runaway reactions,
effective fire engulfment)
Practically relevant tests, special setups
Suitable rooms (autoclave boxes, pilot plant,
outdoor testing range, “explosion pit”) for
special experimental setups, tests under
“critical” conditions
Safety consultancy
• Safety aspects in all stages of process
development and planning
• Advice on safety-relevant characteristics
(“product safety”, “safety data sheet”)
The safety-relevant tests deal with the
determination of parameters for assessing
fire and explosion hazards with respect to
plant and transportation safety.
16 -17

Management team
Certifications
Our certifications and authorisations
• Accreditation according to DIN EN ISO / IEC 17025: 2005 including compliance
with DIN EN ISO 9001: 2000 (German Accreditation Institute DAkkS)
• Environmental management system according to DIN EN ISO 14001: 2005
• Compliance with Section 67 of German Drug Law
• Good Laboratory Practice (GLP) certification
• Registered test laboratory under Sections 26 and 28 of German legislation
relating to protection from immissions
• Registered external test laboratory under Sections 6 (9) of German Hazardous
Substances Regulations
• Approval under Section 3 of BtMG (German Narcotics Act)
The management team (from left to right):
Dr. Hans-Dieter Speikamp (Managing Director),
Dr. Ulrich Schneider, Dr. Sophia Fischer,
Dr. Arndt Müller
• Approval under Section 7 of GÜG (German legislation controlling raw
materials that could be used for production of narcotics)
... our skills are your progress.
18 -19

AQura GmbH
Hanau Site
Rodenbacher Chaussee 4
63457 Hanau, Germany
Marl Site
Paul-Baumann-Straße 1
45772 Marl, Germany
Frankfurt Site
Industriepark Höchst
65926 Frankfurt am Main, Germany
www.aqura.de
Date 10/2011