New Disorder of Serine / Glycine Biosynthesis ... - ERNDIM
New Disorder of Serine / Glycine Biosynthesis ... - ERNDIM
New Disorder of Serine / Glycine Biosynthesis ... - ERNDIM
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<strong>Serine</strong> and <strong>Glycine</strong> <strong>Biosynthesis</strong><br />
Glucose<br />
3-P-Glycerate<br />
Pyruvate<br />
1 2 3<br />
3-P-hydroxypyruvate<br />
1 = 3-P-glycerate dehydrogenase<br />
2 = 3-P-serine aminotransferase<br />
3 = 3-P-serine phosphatase<br />
4 = serine hydroxymethyl transferase<br />
5= <strong>Glycine</strong> cleavage system (NKH)<br />
3-Pserine<br />
serine<br />
glycine<br />
NH3 +<br />
CO2<br />
4<br />
5<br />
THF<br />
MTHF
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