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esc Guidelines<br />

committee for Practice Guidelines<br />

to improve the quality <strong>of</strong> clinical practice and patient care in europe<br />

additional references<br />

Joint esc/eacts Guidelines on<br />

Myocardial revascularisation<br />

For more information<br />

www.escardio.org/guidelines


ESC/EACTS Page 1 <strong>of</strong> 34<br />

Additional references listed by<br />

chapter <strong>of</strong> the full text document<br />

1. Preamble (no references)<br />

2. Introduction ...................................................................................... 1<br />

3. Scores and Risk Stratification, Impact <strong>of</strong> Comorbidity ....... 2<br />

4. Process for Decision Making and Patient Information ........ 3<br />

4.1 Patient information .................................................................. 3<br />

4.2 Multidisciplinary decision making (Heart Team) ............ 3<br />

5. Strategies for Pre-Intervention Diagnosis and Imaging ....... 3<br />

5.1 Detection <strong>of</strong> coronary artery disease ............................... 4<br />

5.2 Detection <strong>of</strong> ischaemia .......................................................... 4<br />

5.3 Hybrid / combined imaging ................................................... 5<br />

5.4 Invasive tests.............................................................................. 5<br />

5.5 Prognostic value ....................................................................... 5<br />

5.6 Detection <strong>of</strong> myocardial viability ........................................ 5<br />

6. Revascularisation for Stable Coronary Artery Disease ...... 5<br />

6.1 Evidence basis for revascularisation ................................... 5<br />

6.2 Impact <strong>of</strong> ischaemic burden on prognosis........................ 6<br />

6.3 Optimal medical therapy versus PCI ................................ 6<br />

6.4 PCI with DES versus BMS ..................................................... 6<br />

6.5 CABG versus medical therapy ............................................ 6<br />

6.6 PCI versus CABG ................................................................. 6<br />

6.7 Recommendations ................................................................... 7<br />

7. Revascularisation in Non ST-segment Elevation ................... 8<br />

Acute Coronary Syndromes<br />

7.1 Intended early invasive or conservative strategies ........ 8<br />

7.2 Risk stratification ..................................................................... 8<br />

7.3 Timing <strong>of</strong> angiography and intervention ........................... 9<br />

7.4 Coronary angiography, PCI and CABG............................. 9<br />

7.5 Patient subgroups ..................................................................... 9<br />

8. Myocardial Revascularisation in ST-segment ......................... 10<br />

Elevation Myocardial Infarction<br />

8.1 Reperfusion Strategies ........................................................... 10<br />

8.2 Mechanical complications ...................................................... 12<br />

9. Special Conditions .......................................................................... 13<br />

9.1 Diabetes ...................................................................................... 13<br />

9.1.1 Indications for myocardial ........................................ 13<br />

revascularisation<br />

9.1.2 Type <strong>of</strong> intervention: CABG .................................... 13<br />

versus PCI<br />

9.1.3 Specific aspects <strong>of</strong> PCI ............................................... 13<br />

9.1.4 Type <strong>of</strong> CABG intervention ..................................... 13<br />

9.1.5 Antithrombotic pharmacotherapy ......................... 13<br />

9.1.6 Antidiabetic medications........................................... 14<br />

9.2 Myocardial Revascularisation in Patients with ................ 15<br />

Chronic Kidney Disease<br />

9.3 Myocardial Revascularisation in Patients .......................... 15<br />

Requiring Valve Surgery<br />

9.4 Associated Carotid / Peripheral Arterial Disease ......... 15<br />

9.4.1 Associated coronary and carotid artery .............. 15<br />

disease<br />

9.4.2 Associated coronary and peripheral arterial ...... 16<br />

disease<br />

9.5 Myocardial Revascularisation in Chronic Heart ............. 16<br />

Failure<br />

9.6 Crossed Revascularisation Procedures ............................. 17<br />

9.6.1 Revascularisation for acute graft failure ............... 17<br />

9.6.2 Revascularisation for late graft failure .................. 18<br />

9.6.3 Revascularisation for acute failure after PCI ...... 18<br />

9.6.4 Elective revascularisation for late failure ............. 19<br />

after PCI<br />

9.6.5 Hybrid procedures ...................................................... 19<br />

9.7 Arrhythmias in Patients with Ischaemic Heart ............... 20<br />

Disease<br />

9.7.1 Atrial fibrillation ........................................................... 20<br />

9.7.2 Supraventricular arrhythmias other ...................... 21<br />

than atrial fibrillation or flutter<br />

9.7.3 Ventricular arrhythmias............................................. 22<br />

9.7.4 Concomitant revascularisation in heart .............. 23<br />

failure patients candidates for<br />

resynchronization therapy<br />

10. Procedural aspects <strong>of</strong> CABG ...................................................... 23<br />

10.1 Preoperative management .................................................. 23<br />

10.2 Surgical procedures .............................................................. 24<br />

10.3 Early postoperative risk....................................................... 24<br />

11. Procedural aspects <strong>of</strong> PCI ............................................................ 25<br />

11.1 Impact <strong>of</strong> clinical presentation ........................................... 25<br />

11.2 Specific lesion subsets .......................................................... 26<br />

11.3 Drug-eluting stents ................................................................ 28<br />

11.4 Adjunctive invasive diagnostic tools ................................. 30<br />

12. Antithrombotic Pharmacotherapy ............................................ 31<br />

12.1 Elective PCI ............................................................................. 31<br />

12.2 Non ST-segment Elevation Acute Coronary ............... 31<br />

Syndrome<br />

12.3 ST-segment Elevation Myocardial Infarction ................ 31<br />

12.4 Points <strong>of</strong> interest and special conditions ....................... 32<br />

13. Secondary prevention.................................................................... 32<br />

13.1 Background and rationale .................................................. 32<br />

13.2 Modalities ................................................................................ 33<br />

13.3 Settings...................................................................................... 33<br />

14. Strategies for follow-up................................................................. 33<br />

2. Introduction<br />

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3. Scores and Risk Stratification,<br />

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4. Process for Decision Making and<br />

Patient Information<br />

4.1 Patient information<br />

Directive 2001/20/EC <strong>of</strong> the <strong>European</strong> Parliament and <strong>of</strong> the<br />

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5.1 Detection <strong>of</strong> coronary artery disease<br />

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404.<br />

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CW, Hueb WA, Kahler J, Kelsey SF, King SB, Kosinski AS, Lopes<br />

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versus a non-invasive strategy in non-ST-elevation acute coronary<br />

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Pieper KS, Gore JM, FitzGerald G, Granger CB, Goldberg RJ,<br />

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7.3 Timing <strong>of</strong> angiography and<br />

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Montalescot G, Cayla G, Collet JP, Elhadad S, Beygui F, Le BH,<br />

Choussat R, Leclercq F, Silvain J, Duclos F, Aout M, Dubois-Rande<br />

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Riezebos RK, Ronner E, Ter BE, Slagboom T, Smits PC, ten Berg<br />

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Ryan JW, Peterson ED, Chen AY, Roe MT, Ohman EM, Cannon<br />

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Manoharan G, Ntalianis A, Muller O, Hamilos M, Sarno G, melikian<br />

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8. Myocardial Revascularisation in<br />

ST-segment Elevation Myocardial<br />

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8.1 Reperfusion strategies<br />

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Acute Coronary Syndromes (GUSTO IIb) Angioplasty Substudy<br />

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HOTLINE II, TRIANA, elderly AMI patients fare better with<br />

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9. Special Conditions<br />

9.1 Diabetes<br />

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9.1.1 Indications for myocardial revascularisation<br />

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1104.<br />

9.1.2 Type <strong>of</strong> intervention: CABG versus PCI<br />

Seven-year outcome in the Bypass Angioplasty Revascularization<br />

Investigation (BARI) by treatment and diabetic status. J Am Coll<br />

Cardiol 2000;35(5):1122-1129.<br />

Frye RL, August P, Brooks MM, Hardison RM, Kelsey SF, MacGregor<br />

JM, Orchard TJ, Chaitman BR, Genuth SM, Goldberg SH, Hlatky<br />

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randomized trial <strong>of</strong> therapies for type 2 diabetes and coronary<br />

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9.1.3 Specific aspects <strong>of</strong> PCI<br />

Lee SW, Park SW, Kim YH, Yun SC, Park DW, Lee CW, Hong<br />

MK, Rhee KS, Chae JK, Ko JK, Park JH, Lee JH, Choi SW, Jeong<br />

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SJ. A randomized comparison <strong>of</strong> sirolimus- versus paclitaxeleluting<br />

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Maeng M, Jensen LO, Galloe AM, Thayssen P, Christiansen<br />

EH, Hansen KN, Helqvist S, Botker HE, Lassen JF, Thuesen L.<br />

Comparison <strong>of</strong> the sirolimus-eluting versus paclitaxel-eluting<br />

coronary stent in patients with diabetes mellitus: the diabetes and<br />

drug-eluting stent (DiabeDES) randomized angiography trial. Am<br />

J Cardiol 2009;103(3):345-349.<br />

9.1.4 Type <strong>of</strong> CABG intervention<br />

Calafiore AM, Di MM. Bilateral internal mammary artery grafting.<br />

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Salehi OA, Karimi A, Ahmadi SH, Davoodi S, Marzban M, Movahedi<br />

N, Abbasi K, Boroumand MA, Davoodi S, Moshtaghi N. Superficial<br />

and deep sternal wound infection after more than 9000 coronary<br />

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thoracic artery harvest increase the risk <strong>of</strong> mediastinitis? Interact<br />

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9.1.5 Antithrombotic pharmacotherapy<br />

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H, Pache J, Dirschinger J, Berger PP, Schomig A. Randomized<br />

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Theroux P, Topol EJ. Platelet glycoprotein IIb/IIIa inhibitors reduce<br />

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Stuckey TD, Stone GW, Cox DA, Tcheng JE, Garcia E, Carroll<br />

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randomized Tailoring Treatment with Tir<strong>of</strong>iban in Patients<br />

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mellitus in the trial to assess improvement in therapeutic outcomes<br />

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9.1.6 Antidiabetic medications<br />

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G, Blanchard D, Lablanche JM, Genes N, Cambou JP. Role <strong>of</strong><br />

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Heupler FA, Jr. Guidelines for performing angiography in patients<br />

taking metformin. Members <strong>of</strong> the Laboratory Performance<br />

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Interventions. Cathet Cardiovasc Diagn 1998;43(2):121-123.<br />

Singh S, Furberg CD. Thiazolidinediones and cardiovascular<br />

outcomes in type 2 diabetes. Heart 2009;95(1):1-3.<br />

9.2 Myocardial Revascularisation in<br />

Patients with Chronic Kidney Disease<br />

K/DOQI clinical practice guidelines for chronic kidney disease:<br />

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2002;39(2 Suppl 1):S1-266.<br />

Chen SL, Zhang J, Yei F, Zhu Z, Liu Z, Lin S, Chu J, Yan J, Zhang R,<br />

Kwan TW. Clinical outcomes <strong>of</strong> contrast-induced nephropathy<br />

in patients undergoing percutaneous coronary intervention: a<br />

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413.<br />

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Sneed JD, Booth DC, Ziada KM. Impact <strong>of</strong> drug-eluting stents<br />

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M, Diarte JA, Rodriguez-Collado J, Rumoroso JR, Lopez-Minguez<br />

JR, Mauri J. Drug-eluting stent thrombosis: results from the<br />

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Hage FG, Smalheiser S, Zoghbi GJ, Perry GJ, Deierhoi M, Warnock<br />

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ML, Ghali WA. Survival after coronary revascularization among<br />

patients with kidney disease. Circulation 2004;110(14):1890-1895.<br />

Heupler FA, Jr. Guidelines for performing angiography in patients<br />

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Interventions. Cathet Cardiovasc Diagn 1998;43(2):121-123.<br />

Iakovou I, Schmidt T, Bonizzoni E, Ge L, Sangiorgi GM, Stankovic<br />

G, Airoldi F, Chieffo A, Montorfano M, Carlino M, Michev I,<br />

Corvaja N, Briguori C, Gerckens U, Grube E, Colombo A.<br />

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Jeong YH, Hong MK, Lee CW, Park DW, Kim YH, Kim JJ, Park SW,<br />

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Kolh PH. Renal insufficiency after cardiac surgery: a challenging<br />

clinical problem. Eur Heart J 2009;43:513-515.<br />

Lemos PA, Arampatzis CA, Hoye A, Daemen J, Ong AT, Saia F, Van<br />

der Giessen WJ, McFadden EP, Sianos G, Smits PC, De FP, H<strong>of</strong>ma<br />

SH, van Domburg RT, Serruys PW. Impact <strong>of</strong> baseline renal<br />

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2005;95(2):167-172.<br />

Lentine KL, Schnitzler MA, Brennan DC, Snyder JJ, Hauptman<br />

PJ, Abbott KC, Axelrod D, Salvalaggio PR, Kasiske B. Cardiac<br />

evaluation before kidney transplantation: a practice patterns<br />

analysis in Medicare-insured dialysis patients. Clin J Am Soc<br />

Nephrol 2008;3(4):1115-1124.<br />

Levey AS, Coresh J, Greene T, Stevens LA, Zhang YL, Hendriksen S,<br />

Kusek JW, Van LF. Using standardized serum creatinine values in the<br />

modification <strong>of</strong> diet in renal disease study equation for estimating<br />

glomerular filtration rate. Ann Intern Med 2006;145(4):247-254.<br />

Recio-Mayoral A, Chaparro M, Prado B, Cozar R, Mendez I,<br />

Banerjee D, Kaski JC, Cubero J, Cruz JM. The reno-protective<br />

effect <strong>of</strong> hydration with sodium bicarbonate plus N-acetylcysteine<br />

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1288.<br />

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C. Early creatinine shifts predict contrast-induced nephropathy<br />

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2010;123:755-763.<br />

Romano G, Briguori C, Quintavalle C, Zanca C, Rivera NV, Colombo<br />

A, Condorelli G. Contrast agents and renal cell apoptosis. Eur<br />

Heart J 2008;29(20):2569-2576.<br />

Stevens LA, Coresh J, Greene T, Levey AS. Assessing kidney<br />

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Stenestrand U, Wallentin L, Jernberg T. Influence <strong>of</strong> renal<br />

function on the effects <strong>of</strong> early revascularization in non-STelevation<br />

myocardial infarction: data from the Swedish Web-<br />

System for Enhancement and Development <strong>of</strong> Evidence-Based<br />

Care in Heart Disease Evaluated According to Recommended<br />

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Witczak BJ, Hartmann A, Jenssen T, Foss A, Endresen K. Routine<br />

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Witczak BJ, Jenssen T, Endresen K, Roislien J, Hartmann A. Risk<br />

factors for mortality in diabetic nephropathy patients accepted<br />

for transplantation. Transplantation 2007;84(3):356-361.<br />

9.3 Myocardial Revascularisation in<br />

Patients Requiring Valve Surgery<br />

Brinster DR, Byrne M, Rogers CD, Baim DS, Simon DI, Couper<br />

GS, Cohn LH. Effectiveness <strong>of</strong> same day percutaneous coronary<br />

intervention followed by minimally invasive aortic valve<br />

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(«hybrid approach»). Am J Cardiol 2006;98(11):1501-1503.<br />

Brown JM, O’Brien SM, Wu C, Sikora JA, Griffith BP, Gammie JS.<br />

Isolated aortic valve replacement in North America comprising<br />

108,687 patients in 10 years: changes in risks, valve types, and<br />

outcomes in the <strong>Society</strong> <strong>of</strong> Thoracic Surgeons National Database.<br />

J Thorac Cardiovasc Surg 2009;137(1):82-90.<br />

Byrne JG, Leacche M, Unic D, Rawn JD, Simon DI, Rogers CD, Cohn<br />

LH. Staged initial percutaneous coronary intervention followed<br />

by valve surgery («hybrid approach») for patients with complex<br />

coronary and valve disease. J Am Coll Cardiol 2005;45(1):14-18.<br />

Feldman DN, Gade CL, Slotwiner AJ, Parikh M, Bergman G, Wong<br />

SC, Minutello RM. Comparison <strong>of</strong> outcomes <strong>of</strong> percutaneous<br />

coronary interventions in patients <strong>of</strong> three age groups (80 years) (from the New York State Angioplasty<br />

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Greelish JP, Ahmad RM, Balaguer JM, Petracek M, Byrne JG.<br />

Reoperative Valve Surgery. In: Cohn LH, ed. Cardiac Surgery in<br />

the Adult. Third Edition ed. New York, McGraw-Hill; 2008. p.<br />

1164-1170.<br />

Grossi EA, Galloway AC, LaPietra A, Ribakove GH, Ursomanno<br />

P, Delianides J, Culliford AT, Bizekis C, Esposito RA, Baumann<br />

FG, Kanchuger MS, Colvin SB. Minimally invasive mitral valve<br />

surgery: a 6-year experience with 714 patients. Ann Thorac Surg<br />

2002;74(3):660-663.<br />

Hannan EL, Samadashvili Z, Lahey SJ, Smith CR, Culliford AT, Higgins<br />

RS, Gold JP, Jones RH. Aortic valve replacement for patients with<br />

severe aortic stenosis: risk factors and their impact on 30-month<br />

mortality. Ann Thorac Surg 2009;87(6):1741-1749.<br />

Iung B, Baron G, Butchart EG, Delahaye F, Gohlke-Barwolf C,<br />

Levang OW, Tornos P, Vanoverschelde JL, Vermeer F, Boersma<br />

E, Ravaud P, Vahanian A. A prospective survey <strong>of</strong> patients with<br />

valvular heart disease in Europe: The Euro Heart Survey on<br />

Valvular Heart Disease. Eur Heart J 2003;24(13):1231-1243.<br />

Khaladj N, Shrestha M, Peterss S, Kutschka I, Strueber M, Hoy L,<br />

Haverich A, Hagl C. Isolated surgical aortic valve replacement<br />

after previous coronary artery bypass grafting with patent grafts:<br />

is this old-fashioned technique obsolete? Eur J Cardiothorac Surg<br />

2009;35:260-264.<br />

LaPar DJ, Yang Z, Stukenborg GJ, Peeler BB, Kern JA, Kron IL,<br />

Ailawadi G. Outcomes <strong>of</strong> reoperative aortic valve replacement<br />

after previous sternotomy. J Thorac Cardiovasc Surg 2010;139:263-<br />

272.<br />

Maganti M, Rao V, Armstrong S, Feindel CM, Scully HE, David<br />

TE. Redo valvular surgery in elderly patients. Ann Thorac Surg<br />

2009;87(2):521-525.<br />

Rumsfeld JS. Valve surgery in the elderly: question <strong>of</strong> quality (<strong>of</strong> life)?<br />

J Am Coll Cardiol 2003;42(7):1215-1217.<br />

Soltesz EG, Cohn LH. Minimally invasive valve surgery. Cardiol Rev<br />

2007;15(3):109-115.<br />

Tabata M, Umakanthan R, Cohn LH, Bolman RM, III, Shekar PS,<br />

Chen FY, Couper GS, Aranki SF. Early and late outcomes <strong>of</strong> 1000<br />

minimally invasive aortic valve operations. Eur J Cardiothorac<br />

Surg 2008;33(4):537-541.<br />

Vahanian A, Alfieri O, Al-Attar N, antunes m, Bax J, cormier b,<br />

cribier a, de Jaegere PP, fournial g, Kappetein AP, Kovac J, ludgate<br />

s, maisano f, moat n, Mohr FW, Nataf P, Pierard L, Pomar J, Sch<strong>of</strong>er<br />

J, Tornos P, Tuzcu EM, van hout b, von segesser l, Walther T.<br />

Transcatheter valve implantation for patients with aortic stenosis:<br />

a position statement from EACTS and ESC, in collaboration with<br />

EAPCI. Eur Heart J 2008;29:1463-1470.<br />

Vahanian A, Alfieri O, Al-Attar N, antunes m, Bax J, cormier b,<br />

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JJ, Tornos P, Tuzcu EM, van hout b, von segesser l, Walther T.<br />

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EAPCI. Eur J Cardiothorac Surg 2008;34:1-8.<br />

9.4 Associated Carotid / Peripheral<br />

Arterial Disease<br />

9.4.1 Associated coronary and carotid artery disease<br />

Abbott AL. Medical (nonsurgical) intervention alone is now best<br />

for prevention <strong>of</strong> stroke associated with asymptomatic severe<br />

carotid stenosis: results <strong>of</strong> a systematic review and analysis. Stroke<br />

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Aboyans V, Lacroix P. Indications for carotid screening in patients<br />

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Baiou D, Karageorge A, Spyt T, Naylor AR. Patients undergoing<br />

cardiac surgery with asymptomatic unilateral carotid stenoses<br />

have a low risk <strong>of</strong> peri-operative stroke. Eur J Vasc Endovasc Surg<br />

2009;38(5):556-559.<br />

Berens ES, Kouchoukos NT, Murphy SF, Wareing TH. Preoperative<br />

carotid artery screening in elderly patients undergoing cardiac<br />

surgery. J Vasc Surg 1992;15:313-321.<br />

D’Agostino RS, Svensson LG, Neumann DJ, Balkhy HH, Williamson<br />

WA, Shahian DM. Screening carotid ultrasonography and risk<br />

factors for stroke in coronary artery surgery patients. Ann Thorac<br />

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9.4.2 Associated coronary and peripheral arterial disease<br />

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9.5 Myocardial Revascularisation in<br />

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