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CUTIS LAXA-LIKE APPEARANCE AUTOIMMUNE DISEASES AND DISEASES OF IMMUNE DYSFUNCTION Complement deficiency Lancet ii:858, 1983 Cutis laxa with hypocomplementemia and nephrotic syndrome AD 123:1211–1216, 1987 Dermatitis herpetiformis Bolognia p.1477, 2003 Lupus erythematosus – systemic LE JAAD 8:869, 1983; lupus panniculitis (lupus profundus) – thighs, buttocks, arms, breasts, face Rook p.2451, 1998, Sixth Edition; Ann DV 117:841–844, 1990 Rheumatoid arthritis – acral cutis laxa JAAD 46:128–130, 2002 Urticaria – acquired cutis laxa JAAD 46:128–130, 2002 CONGENITAL LESIONS Congenital cutis laxa AD 92:373, 1965 DEGENERATIVE DISORDERS Aging DRUG-INDUCED Hypersensitivity reaction AD 123:1211–1216, 1987 Isoniazid (INH) – acquired cutis laxa JAAD 46:128–130, 2002 Minocycline-induced generalized post-inflammatory elastolysis Am J Med 109:340–341, 2000 Penicillamine Cutis 76:49–53, 2005; BJD 142:560–561, 2000; Isr J Med Sci 30:667–669, 1994; Lancet ii:858, 1983 Penicillin allergy – acquired cutis laxa JAAD 46:128–130, 2002; Am J Dermatopathol 5:267–276, 1993 EXOGENOUS AGENTS Leeches applied to skin – anetoderma Int J Derm 35: 226–227, 1996 Saltpeter-induced atrophy INFECTIONS Acrodermatitis chronica atrophicans – Lyme borreliosis Onchocerciasis – ‘hanging groin’ due to destruction of elastic fibers Cutis 65:293–297, 2000 Syphilis – localized cutis laxa JAAD 46:128–130, 2002 INFILTRATIVE DISEASES Amyloidosis – elastolytic lesions of myeloma-associated amyloidosis AD 126:657–660, 1990; Clin Exp Dermatol 11:87–91, 1986; ptosis and dermatochalasis in primary systemic amyloidosis Ophthalmic Surg 18:495–497, 1987; hemodialysis-associated beta-2 microglobulin amyloidosis BJD 152:250–257, 2005 INFLAMMATORY DISEASES Amyotrophic lateral sclerosis JAAD 17:1006–1012, 1987 Angioedema Bolognia p.1477, 2003 Chronic urticaria – acquired cutis laxa JAAD 33:896–899, 1995 Erythema multiforme – acquired cutis laxa JAAD 46:128–130, 2002 Granulomatous slack skin BJD 142:353–357, 2000 Post-inflammatory cutis laxa Bolognia p.1477, 2003; JAAD 22:40–48, 1990 Sarcoid – localized cutis laxa JAAD 46:128–130, 2002 METABOLIC DISEASES Celiac disease – acquired cutis laxa JAAD 46:128–130, 2002; BJD 135:130–134, 1996 Congenital hemolytic anemia Bolognia p.1477, 2003 Gangliosidosis – X-linked; gingival hypertrophy, macroglossia, coarse facies, micrognathia, loose skin, inguinal hernia, delayed growth, hepatosplenomegaly, neonatal hypotonia, delayed motor development Ped Derm 18:534–536, 2001 Lysyl oxidase deficiency Clin Genet 51:109–114, 1997 Marasmus – severe protein and caloric deprivation; wrinkled, loose, redundant dry skin; extensive loss of subcutaneous fat JAAD 21:1–30, 1989 Mucopolysaccharidosis type III (Sanfilippo syndrome) – skin thickened and loose Mucopolysaccharidosis type VII (Sly syndrome) – skin laxity Necrobiosis lipoidica diabeticorum – localized cutis laxa JAAD 46:128–130, 2002 Nephrogenic fibrosing dermopathy, resolved Nephrotic syndrome – acquired cutis laxa JAAD 46:128–130, 2002 Wasting syndrome – cutaneous laxity due to marked weight loss NEOPLASTIC DISEASES Generalized smooth muscle hamartomas with skin folding Granulomatous slack skin syndrome – CD30 + T-cell lymphoproliferative disorder BJD 147:998–1002, 2002 Lymphoma – cutaneous angiocentric T-cell lymphoma – acquired cutis laxa Int J Dermatol 36:772–776, 1997; lymphoplasmacytoid lymphoma AD 131:110–111, 1995; cutaneous T-cell lymphoma (CTCL) – granulomatous slack skin JAAD 51:165–185, 2004; JAAD 46:325–357, 2002; BJD 142:353–357, 2000; Ped Derm 14:204–208, 1997; JID 89:183, 1987; AD 121:250–252, 1985 Myeloma – acquired cutis laxa JAAD 46:128–130, 2002; acral acquired cutis laxa Cutis 69:114–118, 2002; JAAD 21:33–40, 1989; AD 112:853–855, 1976 Neurofibroma – localized cutis laxa JAAD 46:128–130, 2002 PARANEOPLASTIC DISEASES Acquired cutis laxa Bolognia p.1528, 2003 PHOTODERMATOSES Severe actinic damage (dermatoheliosis) CUTIS LAXA-LIKE APPEARANCE 125 PRIMARY CUTANEOUS DISEASES Acanthosis nigricans, generalized – periflexural laxity Ped Derm 18:213–216, 2001 Acral localized acquired cutis laxa BJD 134:973–976, 1996; JAAD 21:33–40, 1989 Anetoderma AD 120:1032–1939, 1984
126 A CLINICIAN’S GUIDE TO DERMATOLOGIC DIFFERENTIAL DIAGNOSIS, VOLUME 1 Blepharochalasis (Fuchs syndrome) Hautarzt 29:474–477, 1978 Cutis laxa Ped Derm 19:412–414, 2002; JAAD 29:846–848, 1993, Ped Derm 2:282–288, 1985 Inherited (dermatochalasis connata) Autosomal dominant Clin Genet 39:321–329, 1991 Autosomal recessive X-linked dominant (occipital horn syndrome (formerly Ehlers–Danlos syndrome type IX) Transient neonatal Acquired – associated with: Type 1 – generalized acquired elastolysis Complement deficiency AD 123:1211–1216, 1987 Drug hypersensitivity Inflammatory skin disease Klippel–Trenaunay–Weber syndrome Malignancy Multiple myeloma Cutis 57:267–270, 1996; Am J Dermatopathol 18:533–537, 1996 Penicillamine dermatopathy AD 125:92–97, 1989 Sarcoid JAAD 29:846–848, 1993 Systemic lupus erythematosus Syphilis Type 2 – Marshall’s syndrome – Sweet’s syndrome followed by cutis laxa AD 131:1175–1177, 1995 Acrolocalized acquired cutis laxa BJD 134:973–976, 1996; JAAD 21:33–40, 1989 Elastoderma – localized skin laxity of the neck, trunk or arm JAAD 53:S147–149, 2005; JAAD 33:389–392, 1995 Elastolysis of the earlobes JAAD 14:145–146, 1986 Elastosis perforans serpiginosa with pseudoxanthoma elasticum-like changes in Moya-Moya disease (bilateral stenosis and occlusion of basa intracranial vessels and carotid arteries) BJD 153:431–434, 2005 Lichen myxedematosus Cutis 39:219–223, 1987 Multiple benign ring-shaped skin creases Eur J Ped 138:301–3,1982 Pseudoxanthoma elasticum – linear and reticulated yellow papules and plaques JAAD 42:324–328, 2000; JAAD 43:337–339, 2000; Dermatology 199:3–7, 1999; AD 133:664–666, 1997; AD 124:1559, 1988; acquired pseudoxanthoma elasticum – farmers exposed to saltpeter (calcium-ammonium-nitrate salts); antecubital fossa JAAD 51:1–21, 2004; Acta DV 78:153–154, 1998; Acta DV 58:319–321, 1978; periumbilical perforating pseudoxanthoma elasticum JAAD 51:1–21, 2004; JAAD 26:642–644, 1992; AD 115:300–303, 1979 SYNDROMES Ablepharon macrostomia syndrome with cutis laxa Hum Genet 97:532–536, 1996 Acrogeria of the Gottron type Eur J Dermatol 10:36–40, 2000 Alagille syndrome – cutis laxa-like changes with resolution of xanthomas after liver transplantation Ped Derm 15:199–202, 1998 Ankyloblepharon–ectrodactyly–cleft lip/palate syndrome (AEC syndrome) – periorbital wrinkling Ascher syndrome Int J Derm 31:710–712, 1992 Barber–Say syndrome – autosomal dominant; wrinkled lax, atrophic skin, hypertrichosis of back and neck, eyebrows, eyelashes, lower lid ectropion, large mouth, and abnormal external ears, hypoplastic or absent nipples, growth retardation Am J Med Genet 86:54–56, 1999 Beare–Stevenson cutis gyrata syndrome – redundant loose facial skin Cantu syndrome Chromosome 6q deletion syndrome – cutaneous and joint laxity Ped Derm 11:281–282, 1994 Coffin–Lowry syndrome – X-linked inheritance; straight coarse hair, prominent forehead, prominent supraorbital ridges, hypertelorism, large nose with broad base, thick lips with mouth held open, large hands, tapering fingers, severe mental retardation; loose skin easily stretched, cutis marmorata, dependent acrocyanosis, varicose veins Clin Genet 34:230–245, 1988; Am J Dis Child 112:205–213, 1966 Costello syndrome – loose skin of neck, hands and feet; papillomas around nose and mouth J Med Genet 31:486–489, 1994 Cutis laxa – autosomal dominant; mild disease of late onset; mutation in elastin gene AD 140:1135–1139, 2004; Ped Derm 21:167–170, 2004; Clin Genet 39:321–329, 1991 Cutis laxa type I – autosomal recessive; diaphragmatic hernia, gastrointestinal and genitourinary diverticulae, pulmonary emphysema, cardiac abnormalities Ped Derm 21:167–170, 2004 Cutis laxa type II – autosomal recessive; pre and postnatal growth retardation, delayed motor development, delayed closure of large fontanelle, congenital hip dislocation, bone dysplasias, parallel strips of redundant skin of back Ped Derm 21:167–170, 2004 Cutis laxa type III – autosomal recessive; severe mental retardation, corneal clouding Ped Derm 21:167–170, 2004 Cutis laxa – X-linked recessive (occipital horn syndrome; formerly Ehlers–Danlos type IX) – lysyl oxidase deficiency, skeletal dysplasias, joint hypermobility, chronic diarrhea, obstructive uropathy Ped Derm 21:167–170, 2004 Cutis laxa, congenital with ligamentous laxity, delayed development, Dandy–Walker malformation, minor heart and osseous defects Clin Genet 45:318–322, 1994 Cutis laxa with bone dystrophy (osteoporosis) Am J Dis Child 137:452–454, 1983 Cutis laxa, craniofacial defects, and hypotonia J Clin Dysmorphol 1:24–25, 1983 Cutis laxa with early-onset emphysema Thorax 49:836–837, 1994 Cutis laxa, late closure of fontanels, intrauterine growth retardation, hyperlaxity of joints Pediatrics 72:850–856, 1983 DeBarsy syndrome – autosomal recessive progeroid syndrome; lax wrinkled skin; cloudy corneas, mental retardation, pseudoathetoid movements, synophrys, pinched nose, thin skin, lack of subcutaneous tissue, sparse hair Ped Derm 19:412–414, 2002; Eur J Pediatr 144:348–354, 1985 Duplication of the eyebrows, stretchable skin and syndactyly Dwarfism–alopecia–pseudoanodontia–cutis laxa Edward’s syndrome (trisomy 18) – cutis laxa of neck, hypertrichosis of the forehead and back, hemangiomas J Med Genet 15:48–60, 1978 Ehlers–Danlos syndrome – scarring; cutis laxa complicating Ehlers–Danlos syndrome type II Clin Exp Derm 21 (2): 135–137, 1996; Ehlers–Danlos syndrome type IX – X-linked Elejalde syndrome (acrocephalopolydactylous dysplasia) Birth Defects 13:53–67, 1977 Gerodermia osteodysplastica (Bamatter syndrome) (osteodysplastic geroderma) – short stature, cutis laxa-like changes with drooping eyelids and jowls (characteristic facies), osteoporosis and skeletal abnormalities; lax skin and joints, growth retardation Am J Med Genet 3:389–395, 1979; Hum Genet 40:311–324, 1978 Hemolytic anemia with emphysema and cutis laxa Hereditary gelsolin amyloidosis (AGel amyloidosis) – cutis laxa, corneal lattice dystrophy, cranial and peripheral polyneuropathy BJD 152:250–257, 2005
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A Clinician’s Guide to Dermatolog
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A Clinician’s Guide to Dermatolog
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Contents Dedication ii Foreword vii
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Pore 524 Port wine stain 524 Preaur
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Introduction Dermatologic different
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ABSCESS AUTOIMMUNE DISEASES, AND DI
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Leishmaniasis (Leishmania major) -
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Kaposi’s sarcoma Lipoma - inflame
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philtrum, thin upper lip, broad mou
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Bacterial cellulitis Candida - Cand
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Comedo-like acantholytic dyskeratos
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Sepsis Streptococcus pneumoniae - w
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Subacute bacterial endocarditis Gha
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PRIMARY CUTANEOUS DISEASES Alopecia
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Necrolytic migratory erythema witho
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Self-healing juvenile cutaneous muc
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Perineurioma - soft tissue perineur
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Lipomatosis of the hands - Madelung
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Osteoarthritis Osteomalacia Polymyo
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DEGENERATIVE DISEASES Follicular de
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Multiple carboxylase deficiency - t
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Porokeratosis of Mibelli of the sca
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Dwarfism-alopecia-pseudoanodontia-c
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Multiple follicular hamartomas with
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XXYY syndrome - features of Klinefe
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Kabuki makeup syndrome - short stat
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ANGIOKERATOMA CORPORIS DIFFUSUM BJD
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Pinta Scabies Skin & Allergy News 2
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Terbinafine AD 131:960-961, 1995 Th
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somatostatin, sulfa, vigabatrin, pi
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Erythema gyratum perstans BJD 58:11
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Trisomy 13 (trisomy D (13-15) - mem
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Serum sickness NEJM 311:1407-1413,
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Rocky Mountain spotted fever Ghatan
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PRIMARY CUTANEOUS DISEASES Acne con
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Pachydermoperiostosis JAAD 38:359-3
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Familial dysautonomia (Riley-Day sy
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Onchocerciasis - atrophic changes e
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Immunocytoma, multiple cutaneous BJ
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type); hypertrophy of lower part of
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Follicular atrophoderma Bazex-Dupre
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Tricho-odonto-onycho-ectodermal dys
Page 86 and 87: Onychomycosis - black nail Ghatan p
Page 88 and 89: DRUG ERUPTIONS Linear fixed drug er
Page 90 and 91: linear and whorled macular pigmenta
Page 92 and 93: Carcinoid syndrome - flushing, patc
Page 94 and 95: PHOTODERMATOSES Lichen planus actin
Page 96 and 97: Pigmented purpuric eruption Purpura
Page 98 and 99: PRIMARY CUTANEOUS DISEASES Atopic d
Page 100 and 101: severe intrauterine growth retardat
Page 102 and 103: Cinnarizine - lichen planus pemphig
Page 104 and 105: Coxsackie A (5,9,10,16) - maculopap
Page 106 and 107: INFILTRATIVE DISEASES Amyloidosis,
Page 108 and 109: JEB cicatricial - autosomal recessi
Page 110 and 111: Superficial mucocoele - oral bulla
Page 112 and 113: INFLAMMATORY DISORDERS Erythema mul
Page 114 and 115: BULLAE IN NEWBORN Textbook of Neona
Page 116 and 117: with or without neuromuscular disea
Page 118 and 119: Orf AD 126:356-358, 1990 Papular ur
Page 120 and 121: INFECTIONS AND INFESTATIONS AIDS -
Page 122 and 123: CALM and pulmonary stenosis Ann DV
Page 124 and 125: Staphylococcus epidermidis AD 120:1
Page 126 and 127: CHALKY MATERIAL EXTRUDED FROM LESIO
Page 128 and 129: PHOTODERMATITIS Acute sunburn Rook
Page 130 and 131: INFILTRATIVE DISEASES Amyloidosis I
Page 132 and 133: Localized lichen myxedematosus (pap
Page 134 and 135: Cowden’s syndrome (multiple hamar
Page 138 and 139: Kabuki makeup syndrome - short stat
Page 140 and 141: CTCL JAAD 29:331-334, 1993 Eruptive
Page 142 and 143: IPEX syndrome - X-linked; immune dy
Page 144 and 145: p.219, 2001; Rook p.636,1006 1998,
Page 146 and 147: Ichthyosis Interstitial granulomato
Page 148 and 149: Hypogammaglobulinemia Ghatan p.107,
Page 150 and 151: Leprosy Lyme disease - including de
Page 152 and 153: INFILTRATIVE DISEASES Langerhans ce
Page 154 and 155: Famotidine (Pepcid) JAAD 31:671-678
Page 156 and 157: and feet; atrophy with mottled hypo
Page 158 and 159: EAR, HARD (PETRIFIED AURICLES) Cond
Page 160 and 161: Protothecosis - verrucous plaque Sc
Page 162 and 163: Granuloma faciale, extrafacial BJD
Page 164 and 165: Greig cephalopolysyndactyly - malfo
Page 166 and 167: Hemangiomas J Pediatr Surg 35:420-4
Page 168 and 169: and face with perioral rugae; aged
Page 170 and 171: Pyomyositis - with purpura JAAD 10:
Page 172 and 173: Distichiasis-lymphedema syndrome -
Page 174 and 175: Itraconazole AD 130:260-261, 1994 V
Page 176 and 177: UNILATERAL FOOT EDEMA Freiberg’s
Page 178 and 179: of the buttocks and thighs with ele
Page 180 and 181: Lymphatic malformation Lymphedema -
Page 182 and 183: Melanocytic nevi - erosions overlyi
Page 184 and 185: Intravenous immunoglobulin (IVIG) B
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Keratosis-ichthyosis-deafness (KID)
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Psoriasis AD 136:875-880, 2000; Ped
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seborrheic dermatitis AD 138:117-12
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Psittacosis - morbilliform eruption
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urticarial, and rubella-like exanth
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CONGENITAL LESIONS Collodion baby R
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Dermatomyositis - eyelid edema JAAD
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METABOLIC DISEASES Acrodermatitis e
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vesiculopustules, red papules, crus
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dermatitis, cribriform scrotal atro
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urticaria, rhinoconjunctivitis Am J
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Parinaud’s oculoglandular fever -
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31:145-158, 1986; Am J Ophtalmol 88
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TOXINS Alkali burn Arsenic poisonin
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PSYCHOCUTANEOUS Anorexia nervosa -
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Ascher’s syndrome Carcinoid syndr
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Histoplasmosis in HIV disease Cutis
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Inverted follicular keratosis J Cli
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Cowden’s syndrome - trichilemmoma
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INFECTIONS AND INFESTATIONS Alterna
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Morphea, linear (en coup de sabre)
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PARANEOPLASTIC Bazex syndrome Necro
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Reactive perforating collagenosis U
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SELF-MUTILATION Hereditary sensory
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Calcium oxalate Am J Kid Dis 25:492
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Connective tissue disease - eosinop
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Herpes simplex infection, chronic i
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Thyroid releasing hormone Thyrotrop
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Diabetes mellitus Epidermolysis bul
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Dentist 24:65-69, 2004; Burkitt cel
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aldehyde Br Dent J 168:115-118, 199
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Job’s syndrome Kindler’s syndro
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Mukamel syndrome - autosomal recess
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Hypertension, post-traumatic Olfact
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Horner’s syndrome - medullary inf
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140:689-695, 1999; JID 103:277-281,
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Melanoma - verrucous and keratotic
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hyperkeratosis, sensorineural deafn
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Juvenile plantar dermatosis Acta DV
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PRIMARY CUTANEOUS DISEASE Acanthosi
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HYPERPIGMENTATION, DIFFUSE AUTOIMMU
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PHOTODERMATOSES Bronze baby syndrom
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Cyclophosphamide - black longitudin
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Liver disease, chronic - diffuse mu
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Pigmentary mosaicism - phylloid hyp
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Pigmented purpuric eruptions includ
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Kaposi’s sarcoma in AIDS JAAD 22:
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Penicillamine Rook p.3395, 1998, Si
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Schinzel-Giedion syndrome - autosom
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Hairy cutaneous malformation of the
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METABOLIC Acromegaly - hirsutism in
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Cornelia de Lange syndrome - specif
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plugged pit; may be verrucous; fili
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Corticosteroids - injected; topical
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Progressive macular hypomelanosis A
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Laser Traumatic scars Clin Inf Dis
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NEOPLASTIC Kaposi’s sarcoma JAAD
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mutation in gene encoding 3β-hydro
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Bruton’s hypogammaglobulinemia -
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Epidermolysis bullosa acquisita IgA
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Atopic dermatitis Confluent and ret
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Romberg’s syndrome - heterochromi
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PSYCHOCUTANEOUS DISEASES Bulimia ne
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spot lentigo (reticulated black sol
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BJD 144:594-596, 2001; JAAD 44:273-
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TRAUMA Minor trauma Dermatol Clin 6
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Trichothiodystrophy syndromes - BID
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Leeches Leishmaniasis - post-kala-a
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AD 109:526-528, 1974; unilateral pu
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SYNDROMES Aarskog syndrome - single
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TOXINS Arsenical keratoses Eosinoph
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Ehlers-Danlos syndrome, type IV - p
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METABOLIC DISEASES Milia-like calci
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Pemphigus vulgaris Scleroderma Sjö
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Down’s syndrome Familial cold urt
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enal failure; associated with hepat
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2003; JAAD 31:561-566, 1994; Ann Rh
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Lipomas BJD 146:125-128, 2002; J Fo
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Familial mitral valve prolapse synd
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Ganglioneuroma of cervical sympathe
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Nailbed or nailplate hemorrhage Rup
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METABOLIC DISEASES Homocystinuria -
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Epstein’s pearls (milia) in oral
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Reticular erythematous mucinosis Se
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Darier’s disease Granuloma facial
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PSYCHOCUTANEOUS DISEASES Factitial
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Phaeoacremonium inflatipes - fungem
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Lichen spinulosus JAAD 22:261-264,
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facial asymmetry, macrostomia, epib
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Juvenile hyaline fibromatosis (syst
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INFECTIONS AND INFESTATIONS Acantha
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Phaeohyphomycosis, subcutaneous Ped
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PHOTODERMATITIS Hydroa vacciniforme
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Congestive heart failure Overwhelmi
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CONGENITAL AND/OR ACQUIRED NEVI Bar
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lipoatrophic streaks extend down le
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Congenital self-healing Langerhans
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Epidermoid cysts, plantar - HPV-60-
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INFLAMMATORY DISEASES Bunion Extrav
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IgM storage papule - pink or skin-c
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Nevus lipomatosis superficialis - m
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1990; Nephron 53:73-75, 1989; dialy
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JAAD 47:251-257, 2002; JAAD 45:596-
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Syphilis Sex Transm Dis 14:52-53, 1
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Vascular calcification - cutaneous
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Arteriovenous fistulae - congenital
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papules JAAD 44:324-329, 2001; prim
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Squamous cell carcinoma Sweat gland
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Leprosy - lepromatous leprosy Rook
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Desmoid tumor - subcutaneous mass i
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PRIMARY CUTANEOUS DISEASES Axillary
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Hemangiopericytoma JAAD 37:887-920,
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Langerhans cell histiocytosis - ulc
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Noonan’s syndrome - keloids Regre
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Malignant fibrous histiocytoma Mela
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JAAD 12:207-212, 1985 Phialophora r
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Merkel cell tumor AD 140:609-614, 2
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esponse element binding protein Ped
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Basan’s syndrome Dermatopathia pi
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PRIMARY CUTANEOUS DISEASES Alopecia
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INFECTIONS Abscess of buccal mucosa
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PRIMARY CUTANEOUS DISEASES Acanthos
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Calcium channel blockers J Am Dent
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Desquamative gingivitis Eosinophili
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Muckle-Wells syndrome Am J Med Gene
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Plaquenil Quinacrine Quinidine - bl
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Malignant schwannoma (neurofibrosar
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METABOLIC DISEASES Acrodermatitis e
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heel Ped Derm 21:655-656, 2004; Med
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AD 124:1678-1682, 1988; JAAD 13:908
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Porokeratosis of Mantoux - craterif
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Epidermolytic hyperkeratosis (bullo
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Sclerodactyly, non-epidermolytic pa
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Incontinentia pigmenti - plantar hy
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Type IX - PPK with sclerodactyly, H
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Eccrine nevus - brown papule JAAD 5
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J Trop Med Hyg 89:43-45, 1986; Bol
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Relapsing linear acantholytic derma
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Keratoacanthoma - digital papule AD
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PHOTODERMATOSES Disseminated superf
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Mixed tumor of the face J Dermatol
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Fibroepithelioma of Pinkus - flat-t
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Bacterial folliculitis, usually sta
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Atrophoderma vermiculatum Ped Derm
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widespread dermatitis, palmoplantar
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Juvenile xanthogranuloma Dis Chest
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SYNDROMES Alagille syndrome (arteri
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Papular urticaria Roseola infantum
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Irritant contact dermatitis Sea urc
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Tanapox - pruritic papule, initiall
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Neurofibroma Neuroma, including sol
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Angiomas, eruptive - treatment with
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Poroma - papilloma, especially of s
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Toxoplasmosis - pityriasis lichenoi
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Keratoacanthoma visceral carcinoma
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Bowen’s disease AD 130:204-209, 1
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Primary lymphoma Leuk Lymphoma 26:4
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Granular cell tumor (granular cell
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paraffinoma resulting in penile enl
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Basal cell carcinoma Genital Skin D
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myopathy JAAD 53:639-643, 2005; AD
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Amebiasis - Entameba histolytica De
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Candidiasis Int J Derm 38:618-622,
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PERIANAL ULCERS, SINGLE OR MULTIPLE
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testis, nasopharyngeal carcinoma; l
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Syphilis - primary (chancre), secon
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Psoriasis Seborrheic dermatitis Vit
Page 520 and 521:
Alprazolam (Xanax) - phototoxic JAA
Page 522 and 523:
Oxyphenbutazone - UVA Paraquat - du
Page 524 and 525:
Occlusive dressings - photosensitiv
Page 526 and 527:
Variegate porphyria - weatherbeaten
Page 528 and 529:
Pityriasis rubra pilaris - seborrhe
Page 530 and 531:
Salvarson Thiazides Tripelennamine
Page 532 and 533:
Juvenile plantar dermatosis Lamella
Page 534 and 535:
Poikiloderma vasculare atrophicans
Page 536 and 537:
Parkes-Weber syndrome - port wine s
Page 538 and 539:
contractures; taut shiny skin; feta
Page 540 and 541:
Red sea coral contact dermatitis In
Page 542 and 543:
BJD 152:1085-1086, 2005; BJD 152:3-
Page 544 and 545:
PSYCHOCUTANEOUS DISEASES Anorexia n
Page 546 and 547:
Terbinifine JAAD 36:858-862, 1997 T
Page 548 and 549:
SYNDROMES Arthropathy, rash, chroni
Page 550 and 551:
Lipoid proteinosis BJD 151:413-423,
Page 552 and 553:
Myotonic dystrophy Syndromes of the
Page 554 and 555:
Mutation in 3β-hydroxysteroid dehy
Page 556 and 557:
virus (Southeast Brazil), Whitewate
Page 558 and 559:
Leptospirosis Meningococcemia Pneum
Page 560 and 561:
Calciphylaxis Chronic renal failure
Page 562 and 563:
Dermatosparaxis - easy bruisability
Page 564 and 565:
Acroangiodermatitis (gravitational
Page 566 and 567:
DRUG-INDUCED Dilantin hypersensitiv
Page 568 and 569:
Streptococcus viridans Strongyloide
Page 570 and 571:
Fogo selvagem JAAD 20:657, 1989 Her
Page 572 and 573:
Coccidioidomycosis - papulopustules
Page 574 and 575:
Tularemia - Franciscella tularensis
Page 576 and 577:
SYNDROMES Behçet’s disease - pap
Page 578 and 579:
Corticosteroid (topical) atrophy; s
Page 580 and 581:
Robert’s syndrome (hypomelia-hypo
Page 582 and 583:
hyperkeratoses extending over Achil
Page 584 and 585:
PRIMARY CUTANEOUS DISEASES Acne vul
Page 586 and 587:
Helicobacter cinaedi - cellulitis A
Page 588 and 589:
Squamous cell carcinoma - intraoral
Page 590 and 591:
Radiation mucositis - intraoral red
Page 592 and 593:
Post-vaccination Semin Pediatr Infe
Page 594 and 595:
Parvovirus B19 infection - red/viol
Page 596 and 597:
Eccrine angiomatous hamartoma Eccri
Page 598 and 599:
Muckle-Wells syndrome Multicentric
Page 600 and 601:
PARANEOPLASTIC DISEASES Cutis verti
Page 602 and 603:
INFECTIONS Coxsackie B4 hemorrhagic
Page 604 and 605:
Hunter’s syndrome - decreased sul
Page 606 and 607:
Progressive cribriform and zosterif
Page 608 and 609:
Pilar cyst (trichilemmal cyst) JAAD
Page 610 and 611:
Ectodermal dysplasias with clefting
Page 612 and 613:
Melanocytic nevus Rook p.1722-1723,
Page 614 and 615:
Microcystic adnexal carcinoma - ski
Page 616 and 617:
Burns Carcinoma Dental sinus Eczema
Page 618 and 619:
INFECTIONS OR INFESTATIONS Brucello
Page 620 and 621:
GEMSS syndrome - autosomal dominant
Page 622 and 623:
Verruciform xanthoma BJD 150:161-16
Page 624 and 625:
EXOGENOUS AGENTS Mustard gas exposu
Page 626 and 627:
INFLAMMATORY DISORDERS Erythema mul
Page 628 and 629:
Abruzzo-Erickson syndrome (cleft pa
Page 630 and 631:
Kenny syndrome (tubular stenosis) C
Page 632 and 633:
Tay syndrome - autosomal recessive,
Page 634 and 635:
Russell-Silver syndrome - large hea
Page 636 and 637:
Dissecting cellulitis of the scalp
Page 638 and 639:
Squamous cell carcinoma Staphylococ
Page 640 and 641:
Nasal alar colobomas, mirror hands
Page 642 and 643:
Mycobacterium avium-intracellulare
Page 644 and 645:
TATTOO, PALPABLE: LESIONS IN A TATT
Page 646 and 647:
hypodontia, short upper lip bound d
Page 648 and 649:
Coats’ disease - cutaneous telang
Page 650 and 651:
NEOPLASTIC DISEASES Actinic keratos
Page 652 and 653:
Neurofibromatosis - usually unilate
Page 654 and 655:
Candidiasis Ghatan p.93, 2002, Seco
Page 656 and 657:
Plummer-Vinson syndrome AD 105:720,
Page 658 and 659:
INFLAMMATORY DISORDERS Crohn’s di
Page 660 and 661:
exanthem with islands of sparing (
Page 662 and 663:
74:278-281, 2000; Br J Plast Surg 5
Page 664 and 665:
central scaling, scarring, atrophy,
Page 666 and 667:
Cryptococcosis - punched out ulcers
Page 668 and 669:
Ulcers with regional adenopathy - a
Page 670 and 671:
Type 9 - ACC as feature of malforma
Page 672 and 673:
Sclerosing lymphangitis of the peni
Page 674 and 675:
Rat bite fever Rhizopus azygosporus
Page 676 and 677:
Felty’s syndrome - arthritis, leu
Page 678 and 679:
Sixth Edition; Int J Dermatol 27:49
Page 680 and 681:
Omphalitis - periumbilical erythema
Page 682 and 683:
DeBarsey syndrome - umbilical herni
Page 684 and 685:
Pyoderma gangrenosum-like lesions,
Page 686 and 687:
DRUG-INDUCED ACE inhibitors - lisin
Page 688 and 689:
Eosinophilic pustular folliculitis
Page 690 and 691:
cold-induced cholinergic urticaria
Page 692 and 693:
Phenylbutazone Phenytoin Piperazine
Page 694 and 695:
LYMPHOCYTIC Peripheral vascular dis
Page 696 and 697:
Cryptococcosis Leishmaniasis - leis
Page 698 and 699:
Leishmaniasis - verrucous form of l
Page 700 and 701:
Pagetoid reticulosis AD 125:402-406
Page 702 and 703:
VASCULAR Angiokeratomas Angiokerato
Page 704 and 705:
Thermal burn - child abuse; vulvar
Page 706 and 707:
DRUGS Corticosteroid-induced fat ne
Page 708 and 709:
PSYCHOCUTANEOUS DISEASES Factitial
Page 710 and 711:
Kaposi’s sarcoma Tyring p.224, 20
Page 712 and 713:
Phenylthiourea - hypopigmentation o
Page 714 and 715:
Griscelli’s syndrome Hallerman-St
Page 716 and 717:
Vogt-Koyanagi-Harada syndrome - occ
Page 718 and 719:
Connective tissue nevus Ped Derm 22
Page 720 and 721:
Retinoid dermatitis - isotretinoin,
Page 722 and 723:
YELLOW NAIL SYNDROME JAAD 28:792-79
Page 724 and 725:
lesions BJ Clin Pract 27:271-273, 1
Page 726 and 727:
PRIMARY CUTANEOUS DISEASE Atopic de
Page 728 and 729:
Plane xanthomas - normolipemic plan
Page 730 and 731:
Dermatomyositis - centripetal flage
Page 732 and 733:
ZOSTERIFORM LESIONS/SEGMENTAL DISOR
Page 734 and 735:
PHOTODERMATOSES Favre-Racouchot syn
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