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Dermatologic Differential Diagnosis.pdf. - Famona Site

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228 A CLINICIAN’S GUIDE TO DERMATOLOGIC DIFFERENTIAL DIAGNOSIS, VOLUME 1<br />

Blushing (physiologic flushing) – emotional<br />

Central nervous system lesions<br />

Autonomic hyperreflexia – spinal cord lesions<br />

Ciliary neuralgia (cluster headaches) – unilateral periorbital<br />

headache with lacrimation and conjunctival injection with<br />

unilateral flushing of the face Rook p.2782, 1998,<br />

Sixth Edition<br />

Destruction of the Gasserian ganglion J Neurol Neurosurg<br />

Psychiatry 46:611–616, 1983<br />

Diencephalic autonomic epilepsy<br />

Horner’s syndrome, including congenital Horner’s syndrome –<br />

unilateral facial flushing J Neurol Neurosurg Psiachiatry<br />

53:85–86<br />

Hypertensive diencephalic syndrome – hyperhidrosis and<br />

blotchy erythema of face and neck with salivation,<br />

tachycardia, and sustained hypertension Rook p.2782, 1998,<br />

Sixth Edition; Rook p.2782, 1998, Sixth Edition<br />

Organic psychosis Ann Intern Med 98:30–34, 1983<br />

Lesions of pons, medulla, cortex<br />

Tumors compressing the third ventricle<br />

Increased intracranial pressure J Neurosurg 92:1040–1044,<br />

2000<br />

Cholinergic urticaria BJD 110:587–910, 1984<br />

Flushing after breaking of a fever<br />

Gustatory flushing, including congenital gustatory flushing<br />

Otolaryngol Head Neck Surg 104:878–880, 1991<br />

Hyperthermia from exercise; from exogenous heat<br />

Physiologic flushing – exercise, emotions, hot drinks<br />

Physiologic gustatory sweating<br />

Spinal cord injuries – facial flushing accompanying profuse<br />

sweating of face, neck, upper trunk with lesions at or above<br />

T6 JAAD 20:713–726, 1989<br />

ANTIDROMIC SENSORINEURAL FLUSHING<br />

Auriculotemporal syndrome (Frey syndrome)<br />

AD 133:1143–1145, 1997<br />

Brainstem and trigeminal nerve involvement<br />

Diabetic autonomic neuropathy<br />

Facial migraine<br />

Familial dysautonomia (Riley–Day syndrome)<br />

Hyperthermia in infants<br />

Interalia tumors of the posterior fossa<br />

Parkinson’s disease<br />

Spinal cord lesions<br />

CIRCULATING VASODILATOR FLUSHING<br />

IV contrast media (iohexol)<br />

Adenosine 3′5′ monophosphate<br />

Aminophylline Ghatan p.245, 2002, Second Edition<br />

Amyl and butyl nitrite<br />

Anti-emetics – alizapride, metoclopramide<br />

Bromocriptine in parkinsonism<br />

Caffeine withdrawal syndrome<br />

Calcium channel blockers – felodipine, nifedipine, amlodipine,<br />

diltiazem JAAD 45:323–324, 2001; BJD 136:974–975, 1997<br />

Carbon monoxide poisoning<br />

Carcinoid syndrome – face, neck, upper trunk associated withs<br />

diarrhea, breathlessness, and wheeze; foregut (stomach, lung,<br />

pancreas, biliary tract) – bright red or pink geographic flush,<br />

sustained, with burning, lacrimation, wheezing, sweating;<br />

hindgut (appendix and ileum) – patchy, violaceous (cyanotic)<br />

flush, intermixed with pallor, short duration BJD 152:71–75,<br />

2005; Rook p.2101, 1998, Sixth Edition; AD 77:86–90, 1958;<br />

edema, telangiectasia, cyanotic nose and face, rosacea Acta<br />

DV (Stockh) 41:264–276, 1961<br />

Chlorpropamide flush Ann Intern Med 95:468–476, 1981<br />

Cholinergic drugs (metrifonate)<br />

Chylomicronemia syndrome – flushing with ingestion of alcohol<br />

Combination anesthesia with isoflurane and fentanyl<br />

Corticosteroids – high dose pulse methylprednisolone; oral<br />

triamcinolone<br />

Cyclosporine<br />

Cyproterone<br />

Diazoxide Ghatan p.246, 2002, Second Edition<br />

Etretinate<br />

Glutamate Ghatan p.246, 2002, Second Edition<br />

Gonadotropin-releasing hormone therapy in patients with<br />

prostatic cancer J North Am Menopause Soc 2:159–161, 1995<br />

Human corticotropin-releasing hormone Clin Investig<br />

72:331–336, 1994<br />

Hydralazine Ghatan p.246, 2002, Second Edition<br />

Hyperbradykininism (Streeten’s syndrome)<br />

Hyperthyroidism<br />

IL-2 reaction JAMA 258:1624–1629, 1987<br />

Iohexol – radiographic contrast medium<br />

Isosorbide dinitrate Ghatan p.246, 2002, Second Edition<br />

Isotretinoin<br />

Metronidazole with or without alcohol<br />

Mithramycin<br />

Morphine<br />

Nicotinamide<br />

Nicotinic acid (high dose) (prostaglandin D2 release) Clin<br />

Pharmacol Ther 50:66–70, 1991<br />

Nifedipine Rook p.2100, 1998, Sixth Edition<br />

Nitrate Ghatan p.246, 2002, Second Edition<br />

Nitroglycerin Rook p.2100, 1998, Sixth Edition<br />

Opiates<br />

Organic solvents<br />

Papaverine Ghatan p.246, 2002, Second Edition<br />

Persantin Ghatan p.246, 2002, Second Edition<br />

Pharmacologic menopause – 4-hydroxy androsterone, danazol,<br />

doxorubicin AD 128:1408, 1992, tamoxifen, clomiphene citrate,<br />

decapeptyl, leuprolide; cancer chemotherapy – doxorubicin,<br />

alpha interferon, methramycin, cacarbazine, cisplatin<br />

Phenolic flavanoids<br />

Phentolamine Rook p.2100, 1998, Sixth Edition<br />

Pheochromocytoma JAAD 46:161–183, 2002<br />

Prostacycline Circulation 106:1477–1482, 2002; Rook p.2100,<br />

1998, Sixth Edition; NEJM 334:296–302, 1996<br />

Prostaglandin E Rook p.2100, 1998, Sixth Edition<br />

Renal cell carcinoma – carcinoid-like syndrome caused by a<br />

prostaglandin secreting renal cell carcinoma Arch Int Med<br />

140:1095–1096, 1980<br />

Reserpine Ghatan p.246, 2002, Second Edition<br />

Rifampin<br />

Tamoxifen

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