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Dermatologic Differential Diagnosis.pdf. - Famona Site

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554 A CLINICIAN’S GUIDE TO DERMATOLOGIC DIFFERENTIAL DIAGNOSIS, VOLUME 1<br />

Thrombotic vasculitis (venous thrombosis) AD 133:1051–1052,<br />

1997<br />

Protein C deficiency<br />

Protein S deficiency<br />

Anti-thrombin III deficiency<br />

Hyperhomocystinemia<br />

Activated protein C resistance<br />

Tufted angioma – purpuric plaque JAAD 20:214–225, 1989<br />

Urticarial vasculitis, including urticarial vasculitis associated<br />

with mixed cryoglobulins, hepatitis B or C infection, IgA<br />

multiple myeloma, infectious mononucleosis, monoclonal IgM<br />

gammopathy (Schnitzler’s syndrome), fluoxetine ingestion,<br />

metastatic testicular teratoma, serum sickness, Sjögren’s<br />

syndrome, systemic lupus erythematous Clin Rev Allergy<br />

Immunol 23:201–216, 2002; JAAD 38:899–905, 1998;<br />

Medicine 74:24–41, 1995; JAAD 26:441–448, 1992<br />

Vasculitis – splinter hemorrhages Ghatan p.85, 2002,<br />

Second Edition; urticarial vasculitis – painful purpuric plaques<br />

on edematous hands AD 141:1457–1462, 2005<br />

Venous stasis – stasis purpura (orthostatic purpura); acute or<br />

chronic; stasis dermatitis Ghatan p.22, 2002, Second Edition<br />

Wegener’s granulomatosis – petechiae, palpable purpura, facial<br />

purpuric plaque JAAD 48:311–340, 2003; AD 130:861–867,<br />

1994; JAAD 10:341–346, 1984; splinter hemorrhages<br />

Ghatan p.85, 2002, Second Edition<br />

PURPURA, NEONATAL<br />

Textbook of Neonatal Dermatology, p.305, 2001<br />

Alloimmune neonatal thrombocytopenia<br />

Alport syndrome variants<br />

Congenital megakaryocytic thrombocytopenia<br />

Drug-related immune thrombocytopenia<br />

Extramedullary hematopoiesis (blueberry muffin baby)<br />

Fanconi’s anemia<br />

Giant platelet syndromes (Bernard–Soulier, May–Hegglin)<br />

Glanzmann’s thrombasthenia<br />

Gray platelet syndrome<br />

Hemorrhagic disease of the newborn<br />

Hereditary clotting factor deficiencies<br />

Hereditary thrombocytopenias<br />

Hermansky–Pudlak syndrome<br />

HIV infection<br />

Infections, multiple organisms<br />

Kasabach–Meritt syndrome<br />

Maternal autoimmune thrombocytopenia (ITP, LE)<br />

Parvovirus B19<br />

Primary platet production/function defects<br />

Protein C deficiency<br />

Protein S deficiency<br />

Purpuric phototherapy-induced eruption<br />

Sepsis<br />

Thrombocytopenia with absent radii syndrome<br />

TORCH syndrome<br />

Trauma<br />

Trisomy 13<br />

Trisomy 18<br />

Vasculitis, cutaneous Rook p.2178, 1998, Sixth Edition<br />

Collagen vascular diseases<br />

Henoch–Schönlein purpura Ped Derm 15:357–359, 1998;<br />

Ped Derm 12:314–317, 1995; Am J Dis Child 99:833–854,<br />

1960; in the adult AD 125:53–56, 1989<br />

Infectious vasculitis (not embolic)<br />

Paraneoplastic vasculitis<br />

Systemic vasculitis<br />

Volkmann ischemic contracture, congenital (neonatal<br />

compartment syndrome) – upper extremity circumferential<br />

contracture from wrist to elbow; necrosis, cyanosis, edema,<br />

eschar, bullae, purpura; irregular border with central white<br />

ischemic tissue with formation of bullae, edema, or spotted<br />

bluish color with necrosis, a reticulated eschar or whorled<br />

pattern with contracture of arm; differentiate from necrotizing<br />

fasciitis, congenital varicella, neonatal gangrene, aplasia cutis<br />

congenital, amniotic band syndrome, subcutaneous fat<br />

necrosis, epidermolysis bullosa BJD 150:357–363, 2004<br />

Wiskott–Aldrich syndrome<br />

X-linked recessive thrombocytopenia<br />

PURPURIC RASH AND FEVER<br />

JAAD 37:673–705, 1997<br />

AUTOIMMUNE DISEASES AND DISEASES<br />

OF IMMUNE DYSFUNCTION<br />

Antineutrophil cytoplasmic antibody syndrome – purpuric<br />

vasculitis, orogenital ulceration, fingertip necrosis, pyoderma<br />

gangrenosum-like ulcers BJD 134:924–928, 1996<br />

Bowel-associated dermatitis-arthritis syndrome<br />

AD 135:1409–1414, 1999; JAAD 14:792–796, 1986;<br />

Mayo Clin Proc 59:43–46, 1984; AD 115:837–839, 1979<br />

Graft vs. host reaction – petechiae AD 125:1685–1688, 1989;<br />

oral purpura Postgrad Med 66:187–193, 1979<br />

Lupus erythematosus – systemic lupus erythematosus with<br />

thrombocytopenia or vasculitis JAAD 48:311–340, 2003; Arch<br />

Fam Med 9:553–556, 2000; purpuric macules, purpuric<br />

urticaria, palpable purpura Rook p. 2152, 1998, Sixth Edition;<br />

BJD 135:355–362, 1996; with antiphospholipid antibodies –<br />

purpura fulminans Haematologica 76:426–428, 1991; splinter<br />

hemorrhages with vasculitis Arch Int Med 116:55–66, 1965;<br />

systemic lupus erythematosus – lesions of palate, buccal<br />

mucosa, gums; red or purpuric areas with red haloes break<br />

down to form shallow ulcers BJD 135:355–362, 1996; BJD<br />

121:727–741, 1989; neonatal lupus JAAD 40:675–681, 1999;<br />

Clin Exp Rheumatol 6:169–172, 1988; follicular petechiae in<br />

SLE BJD 147:157–158, 2002; splinter hemorrhages Ghatan<br />

p.85, 2002, Second Edition<br />

Rheumatoid arthritis – vasculitis – palpable purpura,<br />

petechiae JAAD 53:191–209, 2005; JAAD 48:311–340, 2003;<br />

BJD 147:905–913, 2002; purpuric infarcts of paronychial areas<br />

and digital pads (Bywater’s lesions) purpuric papules<br />

Cutis 71:462, 464, 2003; Rook p. 2184, 1998, Sixth Edition; BJD<br />

77:207–210, 1965; bullae of fingertips and toetips with or<br />

without purpura Rook p. 2184, 1998, Sixth Edition; BJD<br />

77:207–210, 1965; large hemorrhagic lesions, gangrene with<br />

necrotizing arteritis Rook p. 2214, 1998, Sixth Edition; splinter<br />

hemorrhages Ghatan 2002 p.85,172, Second Edition<br />

Serum sickness J Invest Allergol Clin Immunol 9:190–192,<br />

1999; Medicine (Balt) 67:40–57, 1988<br />

Still’s disease – mimicking acute bacterial endocarditis Eur<br />

Heart J 16:1448–1450, 1995

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