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Dermatologic Differential Diagnosis.pdf. - Famona Site

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Serum sickness NEJM 311:1407–1413, 1984; Dermatol Clin<br />

3:107–117, 1985; associated with hepatitis B Arch Int Med<br />

141:623–629, 1981<br />

X-linked chronic granulomatous disease – discoid lupus-like<br />

lesions of face and hands in female carriers of X-linked chronic<br />

granulomatous disease BJD 104:495–505, 1981<br />

X-linked hypogammaglobulinemia (agammaglobulinemia)<br />

J Allergy 33:406–411, 1962<br />

DEGENERATIVE DISEASE<br />

Osteoarthitis – Heberden’s nodes on DIP joints<br />

– Bouchard’s nodes on PIP joints<br />

DRUGS<br />

BCG vaccination – morbilliform or purpuric eruptions with<br />

arthralgia, abdominal pain BJD 75:181–192, 1963; lichenoid and<br />

red papules and papulopustules Ped Derm 13:451–454, 1996<br />

Drug hypersensitivity syndrome AD 132:1315–1321, 1996<br />

Intralesional corticosteroid – periarticular rash Arthritis Rheum<br />

26:231–233, 1983<br />

Isotretinoin therapy for acne vulgaris JAAD 15:1061–1062, 1986<br />

Jarisch–Herxheimer reaction – treatment of syphilis,<br />

onchocerciasis, Lyme disease, strongyloidiasis AD 125:77–81,<br />

1989; Hautarzt 35:588–590, 1984<br />

Methotrexate osteopathy in low dose treatment of psoriasis<br />

AD 132:184–187, 1996<br />

Minocycline hypersensitivity syndrome or lupus-like syndrome<br />

Br Med J 312:169–172, 1996; BJ Rheumatol 674–676, 1994;<br />

Minocycline-induced p-ANCA+ cutaneous polyarteritis nodosa<br />

(vasculitis) JAAD 48:311–340, 2003; JAAD 44:198–206, 2001<br />

Non-pigmenting fixed drug eruption<br />

Sweet’s syndrome – drug-induced JAAD 34:918–923, 1996<br />

EXOGENOUS AGENTS<br />

Epoxy resin-associated fibrosis with arthralgia <strong>Dermatologic</strong>a<br />

161:33–44, 1980<br />

Plants – sharp-tipped leaves of palms or yuccas, rose<br />

thorns – deeply embedded – septic arthritis mimicking bony<br />

tumor J Bone Joint Surg Am 34:386–388, 1952<br />

Sea urchin spine granulomas – initial edema; delayed onset of<br />

bluish papules and nodules (granulomas); fusiform swelling of<br />

digits (synovitis) Clin Exp Dermatol 2:405–407, 1977;<br />

tenosynovitis and arthritis Joint Bone Spine 67:94–100, 2000<br />

Silicone gel breast implants – fever, rash, and arthritis West<br />

J Med 167:149–158, 1997<br />

INFECTIONS AND INFESTATIONS<br />

Actinomycosis of long duration Clin Inf Dis 27:889, 1998<br />

Acute bacterial endocarditis<br />

Adenovirus infection<br />

African histoplasmosis<br />

African tick bite fever (Rickettsia africae) – hemorrhagic pustule,<br />

purpuric papules; transmitted by Amblyomma ticks) – high fever,<br />

arthralgia, myalgia, fatigue, rash in 2–3 days, with eschar,<br />

maculopapules, vesicles, and pustules JAAD 48:S18–19, 2003<br />

African trypanosomiasis AD 131:1178–1182, 1995<br />

Arbovirus fever<br />

Dengue fever<br />

West Nile fever<br />

ARTHRITIS AND RASH 55<br />

O’nyong–Nyong fever – arbovirus; morbilliform eruption, fever,<br />

arthritis; sub-Saharan Africa Tyring p.399, 2002<br />

Sindbis – arbovirus; fever, rash, arthritis; Europe, Asia, Africa,<br />

Australia Tyring p.399, 2002<br />

Ross river fever<br />

Oropouche fever<br />

Phlebotomus fever<br />

Mayaro fever Mayaro – arbovirus; Brazil and Trinidad Tyring<br />

p.399, 2002<br />

Togavirus – morbilliform, maculopapular-petechial (Sindbis<br />

BJD 135:320–323, 1996; BJD 80:67–74, 1968; chickungunya<br />

Trans R Soc Trop Med Hyg 49:28–32, 1955; and<br />

O’Nyong–Nyong fever Trans R Soc Med Hyg 55:361–373,<br />

1961; bunyavirus fevers) with joint pains<br />

Barmah Forest virus – similar to Ross River virus Med J Aust<br />

152:463–466, 1990<br />

Bee and wasp stings – serum sickness as late onset<br />

manifestation NEJM 133:523–527, 1994; J Allergy Clin Immunol<br />

84:331–337, 1989<br />

Bejel (endemic syphilis)<br />

Brown recluse spider bite – purpuric morbilliform eruption in<br />

children at 24–48 hours JAAD 44:561–573, 2001<br />

Calymmatobacterium granulomatis (Donovanosis) – joint pain<br />

and swelling J Clin Inf Dis 25:24–32, 1997<br />

Candida – disseminated Candidiasis JAAD 26:295–297, 1992<br />

Capnocytophaga canimorsus Eur J Epidemiol 12:521–533,<br />

1996<br />

Cat scratch disease – Bartonella henselae; red papule,<br />

becomes vesicle, crusts, ulcerates, heals with scar Am J Dis<br />

Child 139:1124–1133, 1985; JAMA 154:1247–1251, 1954<br />

Chikungunya fever Tyring p.425,513, 2002; Clin Inf Dis<br />

20:225–231, 1995<br />

Fever, chills, severe pain in large joints<br />

Maculopapular eruption of the trunk, extensor surfaces<br />

East Africa, India<br />

Coccidioidomycosis<br />

Dengue fever (flavivirus) – morbilliform or scarlatiniform eruption<br />

on day 3–4, then becomes petechial; classic dengue fever with<br />

joint and bone pain (breakbone fever) with severe backache<br />

JAAD 49:979–1000, 2003; JAAD 46:430–433, 2002; Bull Soc<br />

Pathol Exot 86:7–11, 1993<br />

Dematiaceous fungal infections in organ transplant recipients –<br />

all lesions on extremities – bursitis, synovitis<br />

Alternaria<br />

Bipolaris hawaiiensis<br />

Exophiala jeanselmei, E. spinifera, E. pisciphera, E. castellani<br />

Exserohilum rostratum<br />

Fonsacaea pedrosoi<br />

Phialophora parasitica<br />

Dirofilaria – parasitic rheumatism Cutis 72:269–272, 2003;<br />

subcutaneous dirofilariasis JAAD 35:260–262, 1996<br />

Dracunculus – migration of this nematode into joints Dermatol<br />

Clinic 7:323–330, 1989<br />

Echovirus<br />

Erysipeloid<br />

Glanders – Pseudomonas mallei – cellulitis which ulcerates with<br />

purulent foul-smelling discharge, regional lymphatics become<br />

abscesses; nasal and palatal necrosis and destruction;<br />

metastatic papules, pustules, bullae over joints and face, then<br />

ulcerate; deep abscesses with sinus tracts occur; polyarthritis,<br />

meningitis, pneumonia Rook p.1146–1147, 1998, Sixth Edition<br />

Gonococcemia Am Fam Phys 34:77–79, 1986<br />

Acral purpuric vesicles, pustules<br />

Gray necrotic centers<br />

Hemorrhagic bullae

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