Dermatologic Differential Diagnosis.pdf. - Famona Site

64 A CLINICIAN’S GUIDE TO DERMATOLOGIC DIFFERENTIAL DIAGNOSIS, VOLUME 1
Congenital constriction band of the trunk (variant of amniotic
band syndrome) Ped Derm 14:470–472, 1997
Congenital enteric sinus cyst (split notochord syndrome) – pit
Ped Derm 20:221–224, 2003
Congenital erosive and vesicular dermatitis with reticulate supple
scarring JAAD 32:873–877, 1995, Ped Derm 15:214–218, 1998;
JAAD 17:369–376, 1987; AD 121:361–367, 1985
Congenital varicella syndrome – atrophic scarred limb
Congenital cutis laxa – abdomen; dysplasia of abdominal
muscles Rook p.2017, 1998, Sixth Edition
Dorsal dermal sinus
Facial fusion defect
Linear telangiectatic erythema and mild atrophoderma Cutis
39:69–70, 1987
Melanocytic nevus – hypoplasia underlying a giant congenital
melanocytic nevus Ped Derm 17:387–390, 2000
Midline cervical clefts – vertically oriented atrophic area of
lower anterior neck, associated skin tags or sinus tracts,
fibrous bands connect to platysma muscle AD 141:1161–1166,
2005; Int J Derm 19:479–486, 1980
Myelomeningocoele
Pre-auricular skin defects AD 133:1551–1554, 1997
Ring chromosome 13 syndrome – scalp defect
Sacral dimples
Spinal dysraphism with overlying dimple, sinus, lipoma, faun tail
nevus, dermoid cyst, hemangioma, port wine stain AD
112:1724–1728, 1976
Sternal cleft (congenital midline presternal atrophic defect of the
chest) – congenital atrophic dimple or scar of upper chest
Supraumbilical cleft Textbook of Neonatal Dermatology,
p.120, 2001
Trisomy 13 – scalp defects
Varicella – scarring over dermatomes, limb hypoplasia, low
birth weight, mild mental retardation, cataract, chorioretinitis
Lancet i:1547–1550, 1994
DEGENERATIVE
Age-related fine wrinkling (crinkling) and laxity Rook
p.2004,2019, 1998, Sixth Edition
DRUG-INDUCED
Atrophic scars secondary to drug eruption
Bleomycin – scaly linear erythema of dorsa of hands
with atrophy and telangiectasia (dermatomyositis-like)
JAAD 48:439–441, 2003
Corticosteroid atrophy – systemic, intralesional, topical
corticosteroids Rook p.2006–2007,3550, 1998, Sixth Edition;
AD 126:1013–1014, 1990; perilesional linear atrophic streaks
Ped Derm 4:259–260, 1987; linear atrophy due to intralesional
corticosteroid injections of de Quervain tendonitis Cutis
73:197–198, 2004; oral, inhaled, topical-induced acne rosacea –
papules, pustules, atrophy, telangiectasia Clin Exp Dermatol
18:148–150, 1993; AD Forsch 247:29–52, 1973; multifocal
lipoatrophy due to intravenous cortisol JAAD 46:S130–132,
2002; striae; intra-articular corticosteroid injection
Hydroxyurea – atrophic, scaling, poikilodermatous patches
with erosions on the backs of the hands, sides of the feet JAAD
45:321–322, 2001; atrophy of skin and subcutaneous tissue
JAAD 36:178–182, 1997
Indinivir (protease inhibitor) – striae JAAD 41:467–469, 1999;
lipodystrophy and abnormal fat distribution (crix belly – central
adiposity) JAAD 46:284–293, 2002
Insulin injection lipoatrophy – dimple or more extensive area of
atrophy Ped Derm 11:310–314, 1994
Methimazole and carbimazole – aplasia cutis congenita Ped
Derm 3:327–330, 1986
Methotrexate – semicircular lipoatrophy Ped Derm 19:432–435,
2002
Misoprostol – extensive frontotemporal defects of scalp and
temporal bones Clin Dysmorphol 2:76–80, 1993
Nelfinavir (protease inhibitor) – lipodystrophy and abnormal fat
distribution (crix belly – central adiposity); striae JAAD
46:284–293, 2002
Penicillamine dermatopathy AD 125:92–97, 1989
Phytonadione (fat soluble vitamin K) injection – sclerodermiform
atrophic plaques AD 137:957–962, 2001; AD 121:1421–1423,
1985; Cutis 43:364–368, 1989; JAAD 38:322–324, 1998; Cutis
61:81–83, 1998
Protease inhibitors – facial lipoatrophy BJD 142:496–500, 2000;
lipodystrophy of face, arms, legs, and buttocks with central fat
accumulation of abdomen, breasts, and dorsocervical fat pad
JAAD 50:809–810, 2004
Saltpeter-induced PXE like changes
Saquinavir (protease inhibitor) – lipodystrophy and abnormal fat
distribution (crix belly – central adiposity); striae JAAD
46:284–293, 2002
EXOGENOUS AGENTS
Coal tar products – pitch, asphalt, creosote – diffuse melanosis
of exposed skin; evolves to atrophy, telangiectasia, lichenoid
papules, follicular keratosis Rook p.1791, 1998, Sixth Edition
Smoker’s face – linear wrinkling and atrophy AD 128:255–262,
1992
INFECTIONS AND INFESTATIONS
AIDS – lipoatrophy of face, arms, and legs (associated with
increase fat of abdomen) JAAD 42:727–730, 2000
Botryomycosis – granulomatous reaction to bacteria with
granule formation; single or multiple abscesses of skin
and subcutaneous tissue break down to yield multiple sinus
tracts; small papule; heals with atrophic scars; extremities,
perianal sinus tracts, face Int J Dermatol 22:455–459, 1983;
AD 115:609–610, 1979
Chronic tropical folliculitis
Herpes simplex; congenital herpes simplex infection due to
intrauterine infection – generalized cigarette paper atrophy
J Pediatr 110:97–101, 1987; Ped Derm 4:336–340, 1987
HIV disease – anetoderma AD 128:661–662, 1992
Leprosy – secondary anetoderma; Lucio’s phenomenon –
atrophic scars JAAD 48:958–961, 2003
Lyme borreliosis (Borrelia burgdorferi) – acrodermatitis
chronica atrophicans – red to blue nodules or plaques;
tissue-paper-like wrinkling; pigmented; poikilodermatous;
hands, feet, elbows, knees; subcutaneous nodules of elbows
and knees, with ulnar fibrous bands; sclerosis of lower legs
with ulceration JAAD 49:363–392, 2003; BJD 121:263–269,
1989; Int J Derm 18:595–601, 1979
Molluscum contagiosum, healed – cribriform scarring BJD
144:1094–1095, 2001