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NANOTECHNOLOGY IN THE FOOD CHAIN - Favv

NANOTECHNOLOGY IN THE FOOD CHAIN - Favv

134 implementations of

134 implementations of high-tech innovation (again with a special focus on nanotechnology, biotechnology and ICT) in food or feed industry along a knowledge transfer chain will be awarded with the European Food Implementation Award. The final goal of the project is to set up a European Institute for Food Processing to strengthen the European food industry for global competition. Building blocks for this institute developed within the project include a sustainability action plan, innovation guidelines, fundraising, knowledge transfer schemes, and an Agenda for the White Book on food processing technologies. The latter will allow decision makers to objectively weigh up pros and cons of technologies.

Evaluation and adaption of in vitro testing for the assessment of the toxicity of nanomaterials Paul Troisfontaines & Roel Anthonissen Scientific Institute of Public Health, Department of Health and Surveillance, Toxicology division E-mail: Paul.Troisfontaines@wiv-isp.be Nanoparticles and nanostructured materials have been broadly developed in the past decade and are used in an increasing number of applications and industries (drugs, food, sport, leisure, luxury, surface treatment...). The emergence of materials with new properties, some similar to atmospheric ultrafine particles, raises the question of their safety and especially the adequacy of assessment tools and prevention of risk with these new materials. Risk assessment is particularly difficult in the case of nanomaterials as many uncertainties remain regarding the potential dangers of these new agents. The data on the toxicity of nanomaterials is scarce. Since late 2006, we are developing a program that participates in the evaluation of the potential risks posed by nanomaterials to human health. The evaluation of the robustness of in vitro testing methods (cell viability, oxidative stress and genotoxicity) for hazard assessment of nanomaterials is one of the subjects of research in the toxicology laboratory. If thorough characterization of the material is crucial in the hazard evaluation, the question of the interactions of the particles with the different test systems used for in vitro toxicology is also of great importance. With particles in suspension a classic endpoint quantifier like fluorescence can easily be perturbed and more simply, the particles can interact with the test reagents and induce bias in the outcome of the evaluation. It is therefore important to establish robust methodologies to evaluate the effects of nanoparticles on living systems. We are presently participating in a program where the robustness of genotoxicity methods is assessed with, among others, food grade nanomaterials. This research supports a proposed scientific expertise into broader programs that focus on strategies to define the boundaries of existing risk assessment and propose new methods (Working Party on Manufactured nanomaterials, OECD, 135

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