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Rheumatoid Arthritis

Rheumatoid Arthritis

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Etiology<br />

• Immune mediated chronic inflammation<br />

• Trigger: Environmental<br />

Antigen<br />

Genetic (30%)<br />

Self Antigen<br />

T cell activation<br />

Chronic Inflammation<br />

Lymphoid cells infiltrate synovium<br />

New blood vessels form in synovium<br />

Synovial proliferation<br />

Joint destruction

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