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• Those who had been representatively assigned to the<br />

circumcision group had a 60% (South <strong>Africa</strong>), 53%<br />

(Kenya), <strong>and</strong> 51% (Ug<strong>and</strong>a) lower incidence of <strong>HIV</strong><br />

infection compared to men assigned to the control<br />

group.<br />

• Women indirectly benefit through the reduction in <strong>HIV</strong><br />

prevalence of male partners<br />

• Unclear whether VMMC has positive impact on<br />

reduction in <strong>HIV</strong> transmission via anal sex.- MSM,<br />

transgender<br />

• Does not protect partners of <strong>HIV</strong> positive men who are<br />

circumcised. (CD4 count needs to be >350 for MC)

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