Jay J. Listinsky, MD, Ph.D. Curriculum Vitae - Department of Radiology

Jay J. Listinsky, M.D., Ph.D.
Curriculum Vitae
Date: 9/12/06
CLINICAL APPOINTMENTS:
July 2003-June 2006
July 1988-May 2003
July 1987-June 1988
Radiologist, Section of Breast Imaging
The Cleveland Clinic Foundation
Cleveland, Ohio
Radiologist, Body Imaging and
Mammography Sections,
University of Alabama Hospital
Birmingham, Alabama
Attending Radiologist
Strong Memorial Hospital
Rochester, New York
EDUCATION:
Institution
Mo/Year
University of Wisconsin-
06/1974
Madison
The University of Chicago
08/1979
The University of Chicago
06/1982
Pritzker School of Medicine
Degree
Bachelor of Science
(Molecular Biology)
Doctor of Philosophy (Pharmacology)
Doctor of Medicine
MEDICAL LICENSURE:
State of Ohio
License Number 35-08-2889-L

State of New York
License Number 154818-1
1983-88 and 2004-present
BOARD CERTIFICATION:
American Board of Radiology
(Diagnostic Radiology), 06/1987
POSTDOCTORAL TRAINING:
Month/Year Title Institution
07/1982-06/1983 Resident in Radiology University of
Louisville
Hospitals, Louisville, KY
07/1983-06/1986 Resident in Radiology Strong Memorial
Hospital
Rochester, NY
07/1986-06/1987 Fellow in NMR Research University of
Rochester/
Strong Memorial
Hospital
Rochester, NY
ACADEMIC APPOINTMENTS:
Year Rank/Title Institution
06/2002-present Assistant Professor of Pathology University of Alabama
(Secondary appointment) Hospital
02/1994-05/2003 Assistant Professor of Radiology University of Alabama
(Part-Time, including Leave of Hospital
Absence from 2/94 - 2/97)
07/1988-02/1994 Assistant Professor of Radiology University of Alabama
(Full Time)
Hospital

07/1987-06/1988 Assistant Professor of Radiology University of
Rochester/
Strong Memorial
Hospital
Rochester, NY
AWARDS/HONORS:
N.I.H. Graduate Fellowship, 1975-1976
National Research Service Award, 1976-1978
Co-recipient (with Dr. Robert G. Bryant) of United States Patent #4,927,624
issued May 22, 1990, for "Clay Magnetic Resonance Contrast Agents for
Gastrointestinal Consumption or Introduction."
PROFESSIONAL SOCIETY MEMBERSHIPS:
American Medical Association
International Society for Magnetic Resonance in Medicine
(also member of the MR of Cancer Study Group)
Radiological Society of North America
American Institute of Ultrasound in Medicine
Society of Breast Imaging
American Roentgen Ray Society
Ohio State Medical Association
EDITORIAL SERVICES:
Manuscript Reviewer for Radiology (1989-2002)
Book Reviewer for Radiology (1986-1997)
Poster Reviewer for 9th Annual Meeting of Society for Magnetic Resonance
Imaging (April 1991)
Manuscript Reviewer for Stauffer Award of the AUR (awarded 1991)
GRANT SUPPORT (PAST):
Co-investigator, 1 H NMR Spectroscopy of Whole Cells (Department of Pathology
Award to Principal Investigator: Catherine M. Listinsky, M.S., M.D.), 1992-1998.
Co-investigator (40% effort), “Modulation of breast cancer by α-L-fucose.” (U.S.

Army Medical Research and Materiel Command IDEA Award to Principal
Investigator: Gene P. Siegel, M.D., Ph.D.), 7/15/99-8/14/02.
BIBLIOGRAPHY
MANUSCRIPTS:
Manuscripts published:
1. Listinsky J.J., Kohli J.D. and Goldberg L.I. Consistent unmasking of
dopamine-induced dilation of the canine femoral vascular bed. J Pharmacol Exp
Ther 1980; 215: 662-667.
2. Horn P.T., Kohli J.D., Listinsky J.J. and Goldberg L.I. Regional variation in the
alpha-adrenergic receptors in the canine resistance vessels. Naunyn
Schmiedebergs Arch Pharmacol 1982; 318:166-172.
3. Listinsky J.J., Wood B.P., Ekholm S.E. Parietal osteomyelitis and epidural
abscess: a delayed complication of fetal monitoring. Pediatr Radiol
1986;16:150-151.
4. Listinsky J.J. and Bryant R.G. Gastrointestinal contrast agents: A
diamagnetic approach. Magn Reson Med 1988;8:285-292.
5. Marshall E., Listinsky J.J., Bryant R.G. and Hornak J. Magnetic resonance
imaging using a ribbonator: hand and wrist. Magn Reson Med 1989; 9:369-378.
6. Listinsky J.J. and Griffiths H.J. The shark's fin: a radiologic sign of pillar
fracture-dislocation of the cervical spine. J Med Imaging 1989;3:243-246.
7. Rominger M.B., Kenney P.J., Morgan D.E., Bernreuter W.B., Listinsky J.J.
Gadolinium-enhanced MR imaging of renal masses. RadioGraphics
1992;12(6):1097-1116.
8. Sur S.K., Heinsbergen J.F., Listinsky J.J. and Bryant R.G. Electron spin
resonance and nuclear magnetic relaxation dispersion studies of commercial clay
minerals and zeolites. J Colloid Interface Sci 1993;157:141-146.
9. Wu X. and Listinsky J.J. Effects of transverse cross-relaxation on
magnetization transfer. J Magn Reson Series B 1994;105:73-76.
10. Listinsky J.J., Siegal G.P., Listinsky C.M. α-L-Fucose - a potentially critical
molecule in pathologic processes including neoplasia. Amer J Clin Pathol
1998;110:425-440.

11. Listinsky J.J., Listinsky C.M., Alapati V., Siegal G.P. Cell surface fucose
ablation as a therapeutic strategy for treatment of malignant neoplasms. Adv
Anat Pathol, 2001;8:330-337.
12. Wright H., Listinsky J., Quinn C., Rim A.., Crowe J., Kim, J. Increased
ipsilateral whole breast vascularity as measured by magnetic resonance
angiography (MRA) in patients with breast cancer. (Abstract presented at the
annual meeting of the American Society of Breast Surgeons, March 16-20,
2005.) Am J Surg 2005 Oct; 190(4):576-9.
13. Wright H., Listinsky J., Rim A., Chellman-Jeffers M., Patrick R., Rybicki L.,
Kim J., Crowe, J. MRI as a diagnostic tool for breast cancer in premenopausal
women. (Abstract presented at the annual meeting of the American Society of
Breast Surgeons, March 16-20, 2005.) Am J Surg 2005 Oct; 190(4):576-9. *
*Note: This paper will be abstracted with figures in: Breast Diseases: A Year
Book Quarterly (Mosby-Year Book, Inc., Eva Singletary, ed.) in 2006.
Manuscripts in Preparation:
Listinsky J.J. and Siegal G.P. What's special about fucose? (to be submitted to
Medical Hypotheses).
Shepardson L.B. and Listinsky J.J. The significance of whole-lesion contrast
enhancement patterns as estimated by computer-aided detection (CAD) in MRI
of the breast. (to be submitted to Radiology).
Enriquez, L. and Listinsky, J.: Clinical application of MR imaging in the
management of breast cancer. (submitted to the Cleveland Clinic Journal of
Medicine).
Yuan K., Listinsky C.M., Singh R.K., Listinsky J.J. and Siegal, G.P. Cell
surface associated alpha-L-fucose moieties modulate human breast cancer
neoplastic progression. (submitted to Laboratory Investigation).
ABSTRACTS :
Abstracts Accepted:
Enriquez, L. and Listinsky, J.J. MRI of infiltrating lobular carcinoma sometimes shows
important discrepancies between CAD images and delayed MIP images. Abstract

accepted (Scientific poster exhibit), Radiological Society of North American, The
92nd Scientific Assembly & Annual Meeting, Chicago, IL, 2006.
Bolek, T. and Listinsky, J.J. Changes in CAD-detected patterns of intralesional
enhancement in breast cancer following chemotherapy. Abstract accepted
(Educational exhibit), Radiological Society of North American, The 92nd
Scientific Assembly & Annual Meeting, Chicago, IL, 2006.
Louie, L.D., Crowe, J.P., Listinsky, J.J., Kim, J.A., Dawson, A.E., Obuchowski,
N.A. and Rim, A.S. Accuracy of MRI in estimating breast cancer extent after
chemotherapy. 29th Annual San Antonio Breast Cancer Symposium, San
Antonio, Texas, 2006.
Published Abstracts:
1. Listinsky J.J., Kohli J.D. and Goldberg L.I. Consistent unmasking of
dopamine-induced vasodilation in the canine femoral vasculature by yohimbine.
Pharmacologist 1978; 20:244. (Platform presentation).
2. Listinsky J.J. Actions of selective alpha-adrenergic blocking agents in the
canine femoral vascular bed. Medicine on the Midway 1982;36(4):19. (Platform
presentation).
3. Listinsky J.J., Bryant R.G., Szumowski J., Marshall E., Hornak J. Magnetic
resonance imaging of the testicles using single turn solenoids. Society of
Magnetic Resonance in Medicine, Sixth Annual Meeting, New York, New York,
August 1987; p. 225. (Platform presentation).
4. Marshall E., Listinsky J.J., Bryant R.G. and Hornak J. Magnetic resonance
imaging using a ribbonator: hand and wrist. Society of Magnetic Resonance in
Medicine, Sixth Annual Meeting, New York, New York, August 1987; p. 835.
(Poster exhibit).
5. Listinsky J.J., Marshall E., Bryant R.G., Jones J.A., Lovelock J. and Hornak J.
MRI of the wrist using a perforated single turn solenoid. Society of Magnetic
Resonance in Medicine, Sixth Annual Meeting, New York, New York, August
1987; p. 712. (Poster exhibit).
6. Listinsky J.J., Szumowski J., Bryant R.G. Image contrast maps for gradientrefocused
echo imaging. Society of Magnetic Resonance in Medicine, Sixth
Annual Meeting, New York, New York, August 1987; p. 900. (Poster exhibit).
7. Marshall E., Listinsky J.J., Bryant R.G. and Hornak J.P. Novel resonator
designs. 29th Experimental Nuclear Magnetic Resonance Spectroscopy

Conference (ENC), Rochester, New York, April 1988; p. 149. (Poster exhibit).
8. Listinsky J.J., Bryant R.G., Weiss S.L. Kaolin: first trials as a negative
gastrointestinal MR contrast agent in humans. Society of Magnetic Resonance
in Medicine, Seventh Annual Meeting, San Francisco, California, August 1988, p.
525. (Poster exhibit).
9. Rominger M.B., Kenney P.J., Listinsky J.J. Advances in MRI of the pancreas
at 1.5 T. Society of Magnetic Resonance in Medicine, Tenth Annual Meeting,
San Francisco, California, August 1991, p. 104. (Poster exhibit).
10. Wu X. and Listinsky J.J. Lineshape of magnetization transfer. Society of
Magnetic Resonance in Medicine, Tenth Annual Meeting, San Francisco,
California, August 1991, p. 679. (Poster exhibit).
11. Rominger M.B., Listinsky J.J., Walter M., Bernreuter W.K., Hicks J.N. Can
limited MRI replace high resolution CT in sinusitis? Society of Magnetic
Resonance in Medicine, Tenth Annual Meeting, San Francisco, California,
August 1991, p. 1268. (Poster exhibit).
13. Wu X. and Listinsky J.J. Model of magnetization transfer in MR imaging.
Radiology 1991;181(P):142. (Platform presentation).
14. Rominger M.B., Kenney P.J., Morgan D.E., Listinsky J.J., Bernreuter W.K.
Indications for Gadolinium-enhanced MR imaging for renal mass evaluation.
Radiology 1991; 181(P). (Poster exhibit).
15. Bernreuter W.K., Rominger M.B., Kenney P.J., Listinsky J.J., Blackburn
W.D. Jr., Alarcon G.S. MR imaging of hands in early rheumatoid arthritis.
Radiology 1991;181(P). (Poster exhibit).
16. Rominger M.B., Bernreuter W.K., Lee, D.H., Kenney P.J., Masear V.R.,
Listinsky J.J. Wrist Ligaments: What can be seen at MR imaging and which are
important? Radiology 1991;181(P). (Poster exhibit).
17. Rominger M.B., Bernreuter W.K., Listinsky J.J., Lee D.H., Kenney P.J.,
Colgin S.L. High resolution MR imaging of wrist cartilage. Radiology
1991;181(P). (Poster exhibit).
18. Wu X. and Listinsky J.J. Models of solid-like protein protons in
magnetization transfer imaging. Radiology 1992;185(P):303. (Platform
presentation).
19. Wu X. and Listinsky J.J. Modified Bloch equations and models of
magnetization transfer in MR imaging. The 33rd Experimental Nuclear Magnetic
Resonance Spectroscopy Conference (ENC), Asilomar, CA, April, 1992. (Poster

exhibit).
20. Wu X. and Listinsky J.J. Spin temperature model of solid-like protein protons
in magnetization transfer imaging. Radiology 1993;189(P):349. (Poster exhibit).
21. Listinsky C.M., DeMuth P.A., Sakai T.T., Krishna N.R., Castleberry R.P.,
Listinsky J.J. 1H nuclear magnetic resonance (NMR) spectroscopy of human
acute leukemia. Mod Pathol 1993;6(1):138A. (Poster exhibit).
22. Listinsky C.M., Siegal G.P., Wang M.H., DeMuth P.A., Sakai T.T., Listinsky
J.J. Mobile fucolipid content in the membranes of neoplastic cells: a potential
prognostic marker measured by 1H NMR spectroscopy. Mod Pathol
1994;7(1):142A. (Poster exhibit).
23. Listinsky J.J. and Listinsky C.M. Developing NMR spectroscopy for clinical
use in surgical pathology. Mod Pathol 1994;7(1):165A. (Poster exhibit).
24. Listinsky J.J., Siegal G.P., Wang M.H., DeMuth P.A., Sakai T.T., Listinsky
C.M. Potential clinical use of 1H COSY in surgical pathology. 35th Experimental
Nuclear Magnetic Resonance Conference (ENC), Asilomar, CA, April, 1994.
(Poster exhibit).
25. Listinsky C.M., Siegal G.P., Wang M.H., Castleberry R.P., DeMuth P.A.,
Sakai T.T., Listinsky J.J. Additional evidence for the biological relevance of
fucolipid in the membranes of tumor cells, with proposed practical technical
modifications. Society of Magnetic Resonance, 2nd Meeting Aug. 6-12, 1994.
(Poster exhibit).
26. Listinsky C.M., DeMuth P.A. Jablonsky M., Grubbs C.J., Listinsky J.J. 2-
Dimensional proton NMR correlation spectroscopy of MNU-induced rat mammary
tumors. Mod Pathol 1995;8(1):166A. (Poster exhibit).
27. Listinsky J.J., Listinsky C.M., Myers R.B., Grizzle W.E., DeMuth P.A., Lawing
L.F., Siegal G.P. Alpha-fucosidase reduces the invasiveness of DU-145 prostate
carcinoma cells in vitro. Mod Pathol 1996;9(1):147A. (Poster exhibit).
28. Siegal G.P., Listinsky J.J., Listinsky C.M., Alapati V., Singh R. Fucose
modulates key properties of the malignant phenotype in cultured human breast
cell lines. (Poster exhibit). American Society for Investigative Pathology (ASIP)
annual scientific meeting, Orlando, FL, March 2001.
29. Siegal, G. P., Listinsky, J.J., Listinsky, C. M., Alapati, V., Singh, R. Fucose
modulates key properties of the malignant phenotype in cultured human breast
cell lines. FASEB Journal: Late Breaking Abstracts Supplement 15:49, 2001.
30. Siegal G.P., Listinsky C.M., Alapati V.R., Yuan K., Singh R.K., Listinsky, J.

J. CD44-associated alpha-L-fucose modulates the invasive ability of breast
cancer cells. Abs #1279, Mod Pathol 2002;14(1):308A. 2002.
31. Yuan K., Listinsky C.M., Singh R.K., Xu Y., Listinsky J.J, Siegal G.P. Alpha-Lfucosidase
inhibits breast cancer cell invasion. FASEB Journal 17:A1368, 2003.
32. Yuan K., Listinsky C.M., Singh R.K., Listinsky J.J, and Siegal, G.P. Cell
surface alpha-L-fucose associated CD44 modulates the invasive ability of
human breast cancer cells. Abstracts for the UAB Cell Adhesion and Matrix
Research Center Retreat. Birmingham, AL, April 25, 2003.
33. Yuan K., Rezonzew G., Listinsky J., Listinsky C., Singh R., Kucik D., and
Siegal, G.P. Glycosylation effects on human breast cancer cell adhesion &
invasion are modulated through the simple sugar, fucose. 95th Annual Meeting
Proceedings of the American Association for Cancer Research 46: , 2004.
34. Shepardson L.B. and Listinsky J.J. The significance of whole-lesion contrast
enhancement patterns as estimated by computer-aided detection (CAD) in MRI
of the breast. Radiology 2005;459(P): SSM-01-02 (Scientific session).
35. Quinn C.A. and Listinsky J.J Abnormal vascular enhancement patterns as
adjunct findings of malignancy in MRI of the breast. Radiology
2005;738(P):1048-BP-e. (Educational exhibit).
36. Moeslein F. and Listinsky J.J. The spectrum of MRI findings of ductal
carcinoma in situ as demonstrated by computer-aided detection (CAD).
Radiology 2005;738(P):1051-BP-e. (Educational exhibit).
Thesis/Book Chapters
Listinsky J.J. Actions of dopamine agonists and antagonists in the canine
femoral vascular bed. Ph.D. Thesis, Department of Pharmacological and
Physiological Sciences, The University of Chicago, 1979.
Kohli J.D., Listinsky J.J. and Goldberg L.I. The inhibitory neurogenic effects of
N,N-di-n-propyl dopamine: A vascular dopamine agonist. Proceedings of the
Symposium on Peripheral Dopaminergic Receptors, Strasbourg, France, July,
1978, ed. by J. Imbs and J. Schwartz, pp. 249-255, Pergamon Press, New York,
1979.
Goldberg L.I., Kohli J.D. and Listinsky J.J. Comparison of peripheral pre- and
post-synaptic dopamine receptors. Advances in the Biosciences, "Presynaptic
Receptors," ed. by S. Langer, K. Starke and M. Dubocovich, Vol. 18, pp. 37-4l,
Pergamon Press, New York, 1979.

Goldberg L.I., Kohli J.D., Listinsky J.J., McDermed J.D. Structure activity
relationships of pre- and post-synaptic dopamine receptors mediating
vasodilation. 4th International Catecholamine Symposium, Asilomar, CA,
September, 1978. In Catecholamines: Basic and Clinical Frontiers, ed. by E.
Usdin, I.J. Kopin and J. Barchas, pp. 447-449, Pergamon Press, New York 1979.