Jennifer P. Lee, PharmD, BCPS - Paralyzed Veterans of America
Jennifer P. Lee, PharmD, BCPS - Paralyzed Veterans of America
Jennifer P. Lee, PharmD, BCPS - Paralyzed Veterans of America
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Methodology<br />
• VA electronic medical record (Computerized<br />
Patient Record System)<br />
• Pharmacokinetic calculations via non-steady<br />
state short infusion model 16<br />
o C peak = (Dose/t inf ) * (1-e -kt inf)/V d * K e<br />
o C trough = C peak * e -kt<br />
o CrCl (L/hr) = Vd x Ke<br />
16. Winters M. Basic Clinical Pharmacokinetics. Fourth Ed, 2004, Lippincott Williams and Wilkins.
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