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PROGRAM<br />

page 1<br />

FACULTY<br />

page 5<br />

PRESENTERS<br />

page 13


0630-0900 Registration Open<br />

0700-0800 Sorin Sponsored Breakfast<br />

PATIENT SAFETY SESSIONS<br />

Thursday February 16 th , 2012<br />

Moderator-Susan Englert<br />

0800-0805 Bryan V. Lich, CCP, CPMT Opening Remarks<br />

0805–0855 Bruce Searles, BS, CCP Case Studies in Catastrophe: Could This<br />

Have Happened to you?<br />

0855-0945 David Fitzgerald, BS, CCP Implications & Certification Requirement for<br />

a VAD <strong>Program</strong><br />

0945-1000 Break & Exhibits Open<br />

1000-1050 Bill DeBois Keeping the Cycle of Change Safe<br />

1050-1130 Robert Dunton, MD, FACS Update on Bioethics: Information for<br />

<strong>Perfusion</strong>ists<br />

1130-1230 Nonin Medical Sponsored Lunch<br />

1230-1320 Bruce Searles, BS, CCP Simulation Training for <strong>Perfusion</strong>ists:<br />

Justification & Implementation<br />

1320-1410 Steve Montague Jumpseating in the OR: The <strong>Perfusion</strong>ist<br />

as Safety Observer<br />

1410-1430 Break & Exhibits Open<br />

1430-1520 Robert Dunton, MD, FACS Flying Safely on Bypass<br />

1520-1610 Steve Montague Lifewings: Patient Safety<br />

1610-1700 David Fitzgerald, BS, CCP The Age of Innovation- This is not your<br />

Father’s ECMO Circuit<br />

18:00 – 20:00 Vendor Reception<br />

1


BLOOD MANAGEMENT SESSIONS<br />

Friday February 17 th , 2012<br />

Moderator-Tunisia Ellis<br />

0700-0800 Cytomedix Sponsored Breakfast<br />

Al Stammers, MSA, CCP, CPBMT<br />

An Update on Autologous Platelet-Gel:<br />

Results from Our First 7,000 Procedures<br />

0800-0805 Tunisia Ellis, MS, CCP Announcements<br />

0805-0855 Peter Everts, PhD PRP in Musculoskeletal<br />

0855-0945 David Palmer, EdD, CCP, LP Jefferson Regional Medical Center’s<br />

Experience Using The Viper <strong>Perfusion</strong><br />

Charting System<br />

0945-1000 Break & Exhibits Open<br />

1000-1050 Al Stammers, MSA, CCP, CPBMT Blood Sweat and Fears: Hemostasis<br />

Management Techniques during Cardiac<br />

Surgery<br />

1050-1130 Susan Englert, RN, CCP, CPBMT Blood Management: Tug of War<br />

1130-1230 Covidien Sponsored Lunch<br />

1230-1320 Peter Everts, PhD The Synergy of PRP & Fat Tissue in<br />

Reconstructive Surgery<br />

1320-1410 Dr. Paul DiGiorgi, MD, FACS Minimally Invasive Surgery<br />

1410-1500<br />

Jeffrey Travis, MD, FACS &<br />

Ty Walker, CCP<br />

Eat More Chicken (Open Forum<br />

Discussion)<br />

1500-1515<br />

Break<br />

1515-1605 Charles Roberts, MD CABG in the Setting of Carotid Stenosis:<br />

How to Avoid Stroke<br />

1605-1655 Robin Zappocosta, RN The Time is Right and Size Matters<br />

2


BLOOD MANAGEMENT & NEW TECHNOLOGY SESSIONS<br />

Saturday February 18 th , 2012<br />

Moderator-Ty Walker<br />

0700-0800 Hospira Sponsored Breakfast<br />

Dr. Richard Juda<br />

New Options in Plasma Volume Expansion<br />

In the OR & ICU<br />

0800-0805 Ty Walker, CCP Announcements<br />

0805-0855 Dennis Borne Medical Malpractice Insurance & the<br />

<strong>Perfusion</strong>ist<br />

0855-0945 Jeffrey Travis, MD, FACS Use of a TEG in Cardiac Surgery<br />

0945-1000 Break & Exhibits Open<br />

1000-1100 Keynote Address<br />

James Lonquist, MD, FACS<br />

How to Succeed in Blood Management<br />

1100-1150 Al Stammers, MSA, CCP, CPBMT ProvenCare Medicine: A Primer for Future<br />

Health Care Delivery Models<br />

1150-1250<br />

1250-1340<br />

Haemonetics Sponsored Lunch<br />

Alan Heldman, MD, FACS<br />

Transapical AVR in the Hybrid OR Setting<br />

1340-1430 John Rivera Autotransfusion Quality Control<br />

1430-1445 Break<br />

1445-1535 Gary Allen, MD, FACS Heparin Management During OPCAB<br />

1535-1625 Susan Englert, RN, CCP, CPBMT Patient Safety Issues: Leave Your Ego Out<br />

of the Room<br />

1625-1715 Ty Walker, CCP Simulation Stimulation<br />

1715-1730 Robert Pascotto, MD Heart to Heart Mission: A Tribute to<br />

Volunteers<br />

1900-2200 Party On The Gulf<br />

3


19:00 – 22:00<br />

Sanibel <strong>Perfusion</strong> Symposium’s<br />

Party On The Gulf<br />

LIVE ENTERTAINMENT<br />

SPEAKER EVALUATION & CERTIFICATE LINKS<br />

Online Speaker Evaluations<br />

Online CME Certificates<br />

Note: CME Certificates will be available online 2 weeks after the conference.<br />

4


Faculty<br />

5


BRYAN V. LICH, CCP, CPBMT<br />

I was born in Omaha, Nebraska and attended the University of Nebraska-Lincoln. In college, I first learned about perfusion<br />

while working as a phlebotomist at Bryan Memorial Hospital. After graduating from the University of Nebraska, I went on to<br />

the Texas Heart Institute to study <strong>Perfusion</strong>. I began <strong>Perfusion</strong>.<strong>com</strong> as a student project in 1995 while attending perfusion<br />

school in Houston, TX. After graduation, I moved to Ft. Myers, Florida to begin my career.<br />

Presently, I reside and work in Ft. Myers, Florida as the owner of <strong>Perfusion</strong>.<strong>com</strong>, Inc. I presently serve on the AmSECT<br />

board or directors and the board of directors for the Florida <strong>Perfusion</strong> Society, and I am involved in a number of other<br />

professional societies.<br />

PROFESSIONAL AFFILIATIONS & ACHEIVEMENTS<br />

• Certified by The American Board of Cardiovascular <strong>Perfusion</strong><br />

• Fellow, The American Society of Extracorporeal Technology<br />

• Member, AmSECT Perioperative Blood Management Committee<br />

• Director Zone 3, The American Society of Extracorporeal Technology<br />

• Treasurer, Florida <strong>Perfusion</strong> Society<br />

• Chairman, The International <strong>Perfusion</strong> Association<br />

• Board Member, <strong>Perfusion</strong> Research & Education Foundation<br />

• Director, Heart-to-Heart Mission<br />

• <strong>Perfusion</strong>ist of the Year, Nominee, AmSECT 2007<br />

• Award of Excellence Nominee, AmSECT 2008<br />

• <strong>Perfusion</strong>ist of the Year, AmSECT 2009<br />

6


IRIS J. CHACON, RRT,CCP<br />

Hi, my name is Iris J. Chacon. I was born in Honduras Central America, and at the age of 14 my parents, siblings and I<br />

moved to the United States. It was a very difficult adjustment to make as a teenager. I was unable to speak the English<br />

language and at the same time had to adjust to a different culture. Nevertheless, I survived my first year of school, and<br />

eventually finished High School. After High School, I enrolled as a freshman at Loyola University, in New Orleans. I<br />

graduated from Loyola University with a biology degree, and a minor in both Chemistry and Psychology. Soon after College,<br />

I decided to be in the medical field, and went on to Respiratory School to be<strong>com</strong>e a respiratory therapist. While working as<br />

respiratory therapist, I worked in the NICU unit at Ochsner Hospital in New Orleans. During this time I became involved in<br />

ECMO and became interested in perfusion. After three years as a respiratory therapist, I applied to the perfusion program at<br />

Ochsner Hospital in 1993. I was accepted in the program out of 100 applicants. The <strong>Perfusion</strong> curriculum consisted of a two<br />

year program with only two perfusion students per year accepted into the program. After graduating from the <strong>Perfusion</strong><br />

program, I came to north Florida for my first job. I worked in the Gainesville area for seven years. Subsequently, my<br />

husband and I relocated to Texas for a year. Thereafter, I returned back to Florida, and applied for a job to travel with<br />

perfusion.<strong>com</strong>. I started traveling with PDC in Jan 2003. Since then, I have worked my way up the ladder to be<strong>com</strong>e the<br />

Vice President of perfusion.<strong>com</strong>. I can sincerely state that since then, I have enjoyed every moment of this great adventure<br />

at perfusion.<strong>com</strong>.<br />

7


TUNISIA ELLIS, MS, CCP<br />

Greetings everyone, my name is Tunisia A. Ellis. I was born in Bellevue, NE and grew up in a military family. I spent my<br />

childhood living in Berlin, Germany and Bellevue, Nebraska. I attended The University of Nebraska-Omaha, where I ran<br />

track and studied Biology.<br />

I received my Masters of <strong>Perfusion</strong> Sciences from The University of Nebraska Medical Center and performed my clinical<br />

rotations in Peoria, IL, Kansas City, MO, Omaha, NE and London, England.<br />

After graduation, I accepted my first <strong>Perfusion</strong> position in Orlando, FL. I now reside in Naples, FL working with<br />

<strong>Perfusion</strong>.<strong>com</strong>, Inc. in the Naples, Punta Gorda, & Fort Myers area. I also enjoy traveling as a <strong>Perfusion</strong>ist to accounts<br />

throughout the United States. Thank you for <strong>com</strong>ing to the first Sanibel <strong>Perfusion</strong> Symposium. ENJOY!!<br />

PROFESSIONAL AFFILIATIONS & ACHEIVEMENTS<br />

• Sanibel <strong>Perfusion</strong> Society Meeting Coordinator, <strong>Perfusion</strong>.<strong>com</strong>, Inc. 2011+<br />

• AmSECT Chairman of the 50 th Celebration Committee 2011+<br />

• <strong>Perfusion</strong>ist of the Year, Nominee, AmSECT 2012<br />

• Certified by The American Board of Cardiovascular <strong>Perfusion</strong><br />

• Member, The American Society of Extracorporeal Technology 2000+<br />

• Member, Florida <strong>Perfusion</strong> Society 2008+<br />

• Secretary, Florida <strong>Perfusion</strong> Society 2010<br />

8


C. TY WALKER, CCP, CPBMT<br />

Ty Walker has been a pioneer and vocal advocate for blood management for the last 20 years. Ty has shared his research<br />

and ideas with the perfusion <strong>com</strong>munity at countless meetings throughout his career in perfusion. Recently, Ty’s institution<br />

(St. Francis Hospital, Columbus, GA) has received a PHA Quality and Patient Safety Award and the ITC Award for Patient<br />

Safety & Quality, directly as a result of Ty’s involvement is spearheading a blood management program.<br />

9


SUSAN J. ENGLERT, RN, CNOR, CCP, CPBMT<br />

Having grown up in the small northwestern town of Hill City, Kansas I attended the nearby college of Fort Hays State<br />

University. This gave me the opportunity to participate on the college softball team and the Tiger Deb Dance Drill Team.<br />

After deciding to study nursing, I transferred to St. Mary of the Plains School of Nursing located in Wichita, Kansas. Given<br />

the opportunity to work on the CVOR team, I quickly fell in love with the perfusion profession and enrolled in the St. Mary of<br />

the Plains School of <strong>Perfusion</strong>.<br />

Upon successful <strong>com</strong>pletion of St. Mary's perfusion school, I continued working as a perfusionist for Via Christi Medical<br />

Center and Specialty Care. My 30 years of employment in the Wichita area came to an end when I transferred to Tavares,<br />

Florida for my dream job and a golden opportunity of starting a brand new open heart program at the prestigious Florida<br />

Hospital Waterman and am employed by <strong>Perfusion</strong>.<strong>com</strong>.<br />

I have been happily married for 28 (or 22 depends on who you ask, LOL)...and out of 31, that's not too bad!!! My husband,<br />

John, is currently working in the Afghanistan warzone as the in-county managing auditor on all DoD contracts. I have three<br />

beautiful children, Danielle, 26, obtained her accounting degree and is currently working for the IRS as an tax law research<br />

analyst and instructor. Whitney, 24, also obtained an accounting degree and is currently working toward her MBA. In<br />

addition, she is a certified yoga instructor and is working part time, instructing yoga. My youngest child is my son, Johnny,<br />

21 who is currently attending Kansas State University and is actively applying to perfusion school.<br />

As current President of AmSECT, I am anxiously looking forward to celebrating AMSECT's 50th International Conference at<br />

the Hilton Bonnet Creek Resort in Orlando, Florida, March 28-31. 2012. I would like to extent to all my colleagues, an<br />

invitation to join us for this exciting celebration!!<br />

10


MARCO POLIZZI, RN, MHA, LHRN<br />

I was born in Lucca, Italy and grew up between Florence, Italy & Brussels, Belgium. I spent my childhood living in Belgium<br />

and Italy, and often traveled from England to North Africa. I attended The Brussels State Technical School for Electrical<br />

Engineering, and lived in Belgium till the end of 1989.<br />

I received my Nursing Degree from Edison College, and my Master of Health Care Administration from National-Louis<br />

University, Chicago.<br />

I have more than 10 years of diverse leadership experience as a clinical/administrative manager, educator and perioperative<br />

nursing while promoting professional healthcare delivery, supported by progressive clinical coaching, and<br />

clinical/administrative staff development.<br />

11


PETER M. ZUCK, RN, CCP<br />

I was born and raised in St. Louis, Missouri and graduated from Washington University with a major in Architectural<br />

Design. I received my RN from Barnes Hospital, part of the Washington University Medical Center, where I worked in<br />

open heart as a scrub nurse. I graduated from Texas Heart Institute in 1988 and received a BS from the University of<br />

Texas in perfusion technology. I’ve worked in Southwest Florida as a perfusionist ever since and am currently employed<br />

as the credentialing officer and service manager for <strong>Perfusion</strong>.Com. I’m a former executive board member of the Florida<br />

<strong>Perfusion</strong> Society and the clinical coordinator and chief perfusionist at Gulf Coast Medical Center. I’m a retired rugby<br />

player, advanced scuba diver, and avid golfer. I also volunteer my time with the Boy Scouts of America and have two<br />

sons active in scouting.<br />

12


Presenters<br />

13


Thursday, February 16 th , 2012<br />

Patient Safety Sessions<br />

Moderator-Susan Englert<br />

Bruce Searles, BS, CCP<br />

Case Studies in Catastrophe: Could this have<br />

happened to you?<br />

Through the careful dissection of real life<br />

perfusion catastrophes and the system failures<br />

that made them possible, this presentation will<br />

illuminate aspects of every professionals practice<br />

and illustrate how they can contribute, positively<br />

or negatively, to the safety of your patients.<br />

Audience participation will be encouraged and<br />

practical suggestions will be made to help reduce<br />

the risk of crisis for the cardiac surgery patient.<br />

14


David Fitzgerald, BS, CCP<br />

Implications & Certification Requirement for a<br />

VAD <strong>Program</strong><br />

Despite aggressive pharmacological therapies,<br />

nearly 280,000 patients die every year from<br />

advanced heart failure. Although heart<br />

transplantation remains the standard of care for<br />

this patient population, the demand for organs<br />

greatly exceeds the number of suitable donors.<br />

As a result, clinicians have turned to<br />

alternative options in the treatment of advanced<br />

refractory heart failure. The recent emergence of<br />

second and third generation ventricular assist<br />

devices (VAD’s) may seemingly improve longterm<br />

patient out<strong>com</strong>es, as the large and pulsatile<br />

implantable devices give way to smaller and<br />

more durable pumps designed to reduce devicerelated<br />

<strong>com</strong>plications and optimize patient quality<br />

of life. Improvements in mechanical pump design<br />

would benefit patients waiting for an organ as<br />

well as those who do not qualify<br />

for transplantation, referred to as Destination<br />

Therapy.<br />

Over the last couple years, several new<br />

technologies have been introduced to treat<br />

advanced heart failure, with many more<br />

anticipated devices on the horizon.<br />

Cardiovascular <strong>Perfusion</strong>ists should be expected<br />

to be key members of an institutional<br />

mechanical circulatory assist program, as our<br />

formal education provides a perfect <strong>com</strong>plement<br />

of patient physiology and extracorporeal<br />

technology. But the challenge will be maintaining<br />

our proficiency with each new device in this<br />

rapidly growing industry. In particular, continued<br />

education for perfusionists,<br />

Identifying practice guidelines and performance<br />

measures, participating in the Joint Commission<br />

certification process, and the creation of<br />

appropriate standards all designed to optimize<br />

patient safety and out<strong>com</strong>e.<br />

Affiliation:<br />

Chief of Cardiovascular <strong>Perfusion</strong><br />

INOVA Heart and Vascular Institute<br />

INOVA Fairfax Hospital for Children<br />

(703) 776-3728 voice<br />

(703) 776-2830 fax<br />

david.fitzgerald@inova.org<br />

15


Bill DeBois, CCP, MBA<br />

Keeping the Cycle of Change Safe<br />

Abstract:<br />

Continuous change is a key ingredient in the<br />

improvement process. The desire for such<br />

change can <strong>com</strong>e about either by a need to<br />

improve current conditions, implementation of<br />

best practices or just a quest to be the best. In<br />

which case you will not follow the pack, but rather<br />

blaze your own trail. The important concept is to<br />

track both the changes and results very closely.<br />

The goal of change should be an improved state.<br />

Occasionally though, the goal or aim may be<br />

overlooked or the constraints and barriers not<br />

fully understood. While change may be desired,<br />

it may not be <strong>com</strong>municated well enough to<br />

those who are needed to assist in the change.<br />

Also overlooked is the recruitment of<br />

knowledgeable and enthusiastic stakeholders<br />

who will help to drive the change forward, and<br />

most importantly they will help identify any<br />

potential problems that may result from the<br />

change.<br />

Techniques used by behavioral psychologists<br />

may be helpful in easing the cycle of change<br />

process. A technique known as motivational<br />

interviewing is based on the assumption that our<br />

behaviors are a product of our thoughts and our<br />

feelings. Individuals may understand that while<br />

something<br />

may be bad for us it may not necessarily lead us<br />

to change our behavior. To change one’s<br />

behavior it may also be necessary to change the<br />

feelings as well. For example, process<br />

participants must be<strong>com</strong>e un<strong>com</strong>fortable with the<br />

current state.<br />

The key to healthcare organizations<br />

implementing change is their ability to rapidly<br />

spread innovations and new ideas, which are<br />

generated from projects. As an example,<br />

improvements in glucose control in a cardiac<br />

intensive care unit may not be implanted into<br />

other areas of the hospital. Leadership needs to<br />

assure that these best practice methods are<br />

universally accepted throughout the organization.<br />

When considering opportunities, improvement<br />

teams are organized to focus on a project to<br />

solve problems that are crippling organizational<br />

performance. The results however should be<br />

considerably greater than the required effort of<br />

the project. The performance elements that need<br />

to be considered are:<br />

16


1. Cycle Times (Turn-around times)<br />

2. Costs (Inventory costs)<br />

3. Output capacity (Improved, out<strong>com</strong>es,<br />

caseloads)<br />

4. Satisfaction (Both employee and patient)<br />

5. Revenue Potential<br />

Plan, Do, Check, Act is an elegant methodology<br />

for change. It starts with a problem statement,<br />

proceeds through a planning and data collection<br />

phase and re-evaluation. For continuous<br />

improvement, this cycle must be forward moving<br />

and permanently adjusted.<br />

17


Dr. Robert Dunton, FACS<br />

Update on Bioethics: Information for<br />

<strong>Perfusion</strong>ists<br />

<strong>Perfusion</strong>, as a medical profession, is an<br />

important <strong>com</strong>ponent of the overall care team of<br />

patients, and as such is subject to the same<br />

ethical expectations as all healthcare providers.<br />

A brief overview of the basic principles of medical<br />

ethics is presented, with special reference to the<br />

role provided by perfusionists.<br />

18


Bruce Searles, BS, CCP<br />

Simulation Training for <strong>Perfusion</strong>ists:<br />

Justification & Implementation<br />

High fidelity simulation is being increasingly<br />

utilized to educate health professionals for both<br />

students preparing to enter the field and<br />

professionals in clinical practice. The scope of<br />

practice of the cardiovascular perfusionist is very<br />

technical and based on physiologic data that is<br />

be<strong>com</strong>ing easier to simulate. This <strong>com</strong>bination<br />

makes perfusion ideally suited for very high<br />

quality simulation training. This presentation will<br />

review the justification for integrating simulation<br />

training into the perfusionist’s professional life,<br />

starting in school and continuing throughout your<br />

career. Models of successfully implemented and<br />

proposed simulation training programs will be<br />

reviewed. <strong>Perfusion</strong>ists’ with more than 10 years<br />

left in their career may find this presentation’s<br />

closing predictions to be very interesting.<br />

19


Steve Montague<br />

Jumpseating in the OR: The <strong>Perfusion</strong>ist as<br />

Safety Observer<br />

Crew Resource Management (CRM) is a human<br />

factors “bundle” that evolved in<br />

<strong>com</strong>mercial aviation to address short<strong>com</strong>ings in<br />

teamwork and <strong>com</strong>munication. As<br />

CRM evolved, crews realized that their<br />

contribution to flight safety exceeded just their<br />

own particular flight responsibilities. Every<br />

crewmember is responsible for overall<br />

flight safety as a collateral duty. Because<br />

perfusionists are normally prepared to go on<br />

bypass well in advance of the rest of the OR<br />

team, they are a knowledgeable clinician<br />

with a temporarily low task loading. During this<br />

time, the perfusionist is ideally suited<br />

to assist the team, and ultimately the patient, by<br />

serving as a safety observer.<br />

During this interactive session we’ll discuss the<br />

background of CRM, its application in<br />

healthcare, and recent results. We’ll also provide<br />

context for specific applications of<br />

CRM behaviors and orient these behaviors to<br />

standardized actions or events (checklists,<br />

protocols, etc). Finally, we’ll discuss how the<br />

perfusionist can further integrate<br />

themselves into the OR team and foster effective<br />

teamwork.<br />

Overall Course Objectives: Upon <strong>com</strong>pletion of<br />

the seminar, participants should be<br />

able to improve patient out<strong>com</strong>es by being able<br />

to:<br />

• Discuss the results that have been achieved by<br />

organizations who have<br />

implemented CRM.<br />

• Demonstrate a simple technique to make an<br />

assertive statement to address a<br />

perceived patient safety concern.<br />

• Identify specific performance improvements<br />

that perfusionists can expect to see<br />

20<br />

when teams routinely implement CRM behaviors.<br />

CRM teaches universal skills that enhance<br />

<strong>com</strong>munication and collaboration among<br />

members of teams engaged in high consequence<br />

endeavors.<br />

Affiliation:<br />

LifeWings Partners, LLC<br />

1163 Halle Park Circle<br />

Collierville, TN 38017<br />

Biography:<br />

Steve Montague serves as the Executive Vice<br />

President for LifeWings and has over 30 years<br />

experience in aviation. Captain Montague is an<br />

engaging facilitator and TeamSTEPPSTM Master<br />

Trainer with a vast amount of experience in the<br />

design and implementation of CRM-based<br />

patient safety programs. He has provided<br />

program implementation for over 45 clients


including Vanderbilt University Medical Center,<br />

Rush University Health Center, Vassar Brothers<br />

Medical Center, Ohio State University Medical<br />

Center, and University of California—Los<br />

Angeles.<br />

Prior to joining LifeWings, Mr. Montague was a<br />

Naval Aviator and served as a fighter pilot, flight<br />

instructor, course developer, procurement<br />

consultant, and <strong>Program</strong> Model Manager at the<br />

U.S. Navy’s Landing Signal Officer School. He<br />

has over 15,000 flight hours and more than 350<br />

carrier landings. Mr. Montague currently serves<br />

as a Captain and First Officer for a major<br />

international airline. He has an Airline Transport<br />

Pilot rating and is qualified in the MD80, B757,<br />

B767, DC10, and MD11.<br />

Captain Montague is an internationally sought<br />

after keynote speaker whose most recent<br />

engagements include the National Council of<br />

State Boards of Nursing, the International<br />

Meeting on Simulation in Healthcare, the<br />

Karolinska Institute, and the Western Graduate<br />

Education Association.<br />

Mr. Montague graduated from the U.S. Naval<br />

Academy with a Bachelor of Science degree in<br />

Aerospace Engineering, and is currently pursuing<br />

his Master of Science degree in Human Factors<br />

and System Safety.<br />

21


Robert Dunton, MD, FACS<br />

Flying Safely on Bypass<br />

Critical to the safe conduct of cardiopulmonary<br />

bypass is adherence to the use of checklists.<br />

Following proscribed procedures in an orderly<br />

and well-documented fashion leads to<br />

predictable and safe out<strong>com</strong>es. Such practice is<br />

well associated with improved out<strong>com</strong>es in other<br />

endeavors, most notably in aviation. The<br />

parallels between safe flying and safe perfusion<br />

have been documented previously, and are<br />

worthy of further consideration.<br />

Biography:<br />

Dr. Dunton is a board-certified cardiothoracic<br />

surgeon. Prior to joining Bon Secours, he had<br />

been a cardiothoracic surgeon at Dartmouth<br />

Hitchcock Medical Center in Concord, N.H. since<br />

2001. He has served as the medical coordinator<br />

of the Concord Hospital Open Heart <strong>Program</strong><br />

and as an assistant professor of surgery at<br />

Dartmouth Medical School. He has been involved<br />

in academic activities at Northeastern University<br />

<strong>Perfusion</strong> Training <strong>Program</strong> and research<br />

activities for the Northern New England<br />

Cardiovascular Disease Study Group.<br />

Dr. Dunton received a Bachelor’s degree in<br />

biology from Baldwin-Wallace College in Berea,<br />

Ohio, and his medical degree from Albany<br />

Medical College in Albany, N.Y. He did a general<br />

surgery internship and residency at Hartford<br />

Hospital in Hartford, Conn., where he received<br />

the Upjohn Outstanding Intern Award. He was a<br />

senior resident in cardiac surgery at Boston<br />

Children’s Hospital and <strong>com</strong>pleted a fellowship in<br />

cardiothoracic surgery at New England<br />

Deaconess Hospital in Boston. Dr. Dunton has<br />

also earned a Master's degree in Bioethics from<br />

the Union Graduate College and the Mt. Sinai<br />

School of Medicine in New York, NY.<br />

He has co-authored and published numerous<br />

articles and has presented papers to many<br />

surgical societies. He has been a member of the<br />

American Heart Association Council on<br />

Cardiovascular Surgery and Anesthesia since<br />

2004. Dr. Dunton is a Fellow in the American<br />

College of Surgeons and the American College<br />

of Chest Surgeons and a member of the Society<br />

of Thoracic Surgeons.<br />

22


Steve Montague<br />

Lifewings: Patient Safety<br />

Patient safety is the responsibility of every<br />

clinician, but organizations also have a<br />

responsibility to put safe systems into place to<br />

support safe practices. These safe practices<br />

must take place in an environment that includes<br />

<strong>com</strong>peting pressures such as production, cost,<br />

equal access, confidentiality, etc. High Reliability<br />

Organizations (HROs) such as aircraft carrier<br />

flight deck crews, nuclear submarines, and wild<br />

land<br />

firefighting crews have learned some important<br />

lessons that should be implemented in<br />

healthcare.<br />

Several case studies will be discussed, with<br />

critical lessons learned from High Reliability<br />

Organizations applied to healthcare settings.<br />

Among the results published in peer-reviewed<br />

literature, are these:<br />

Surgical death rate decreased 47%<br />

Inpatient <strong>com</strong>plications decreased 36%<br />

Surgical Site Infection rate decreased 45%<br />

Unplanned return to OR rate decreased 25%<br />

Conclusion: Thoughtful application of evidence<br />

based practices from other high consequence<br />

professions can yield substantially better patient<br />

out<strong>com</strong>es.<br />

23


David Fitzgerald, BS, CCP<br />

The Age of Innovation- This is not your<br />

Father’s ECMO Circuit<br />

Over the last several years, many ECMO<br />

clinicians have experienced a significant change<br />

in both circuit technology and design. Large<br />

silicone oxygenators and roller pumps have given<br />

way to smaller, more bio<strong>com</strong>patible and reliable<br />

<strong>com</strong>ponents, as evidenced by the ELSO<br />

Registry. In both pediatric and adult ECMO, the<br />

new design in extracorporeal circuitry has been<br />

credited to improved patient care, as less<br />

hemolysis, blood transfusions, and mechanical<br />

disturbances have helped clinicians optimize safe<br />

out<strong>com</strong>es for this critical population of patients.<br />

Anecdotally, these improvements have also not<br />

only lead to not only the expansion of indications<br />

for support, but also may allow for prolonging the<br />

duration of ECMO support.<br />

Affiliation:<br />

Chief of Cardiovascular <strong>Perfusion</strong><br />

INOVA Heart and Vascular Institute<br />

INOVA Fairfax Hospital for Children<br />

(703) 776-3728 voice<br />

(703) 776-2830 fax<br />

david.fitzgerald@inova.org<br />

24


Friday, February 17 th , 2012<br />

Blood Management Sessions<br />

Moderator-Tunisia Ellis<br />

Peter Everts, PhD<br />

PRP in Musculoskeletal Injuries<br />

Abstract:<br />

Musculoskeletal injuries represent a large<br />

number of both professional, and recreational<br />

sports injuries. In the US, The prevalence for<br />

sports injuries is more than 11% in the<br />

Netherlands, with approximately more than 2.5<br />

million injuries per year. These injuries are often<br />

located in the myotendinous junction. Treatment<br />

options are extensively, depending on the<br />

severity of the trauma, but has remained limited<br />

mostly to immobilization, cooling, <strong>com</strong>pression,<br />

elevation, pain medication, anti-inflammatory<br />

drugs, and ultimately mobilization.<br />

At present, new biological treatment strategies, to<br />

enhance muscle and tendon healing, have <strong>com</strong>e<br />

available. Furthermore, patients expect faster<br />

and less invasive treatment options.<br />

Autologously prepared platelet rich plasma (PRP)<br />

is a volume of plasma with, among others, high<br />

concentrations of platelets containing several<br />

growth factors. PRP applications have been<br />

extensively described in the literature as a<br />

Potential PRP application techniques in patients<br />

with musculoskeletal injuries, relevant to<br />

physicians who treat musculoskeletal injuries,<br />

like lateral epicondilitis of the elbow, Achilles<br />

tendon tendinopathies, patella tendon<br />

tendinopathies, and other regions will be<br />

described.<br />

PRP matrix grafts along with other biologic<br />

grafting techniques are be<strong>com</strong>ing more prevalent<br />

in the treatment paradigms of musculoskeletal<br />

medicine. These PRP matrix grafts provide<br />

effective, safe, relatively low- cost treatment.<br />

Potential PRP application techniques in patients<br />

with musculoskeletal injuries, relevant to<br />

physicians who treat musculoskeletal injuries,<br />

like lateral epicondilitis of the elbow, Achilles<br />

tendon tendinopathies, patella tendon<br />

tendinopathies, and other regions will be<br />

described.<br />

PRP matrix grafts along with other biologic<br />

grafting techniques are be<strong>com</strong>ing more prevalent<br />

25


in the treatment paradigms of musculoskeletal<br />

medicine. These PRP matrix grafts provide<br />

effective, safe, relatively low- cost treatment<br />

options to patients who have the time and<br />

wherewithal to allow collagen synthesis and<br />

maturation at the graft site. PRP matrix grafts<br />

appear to restore tissue homeostasis and<br />

biotensegrity of collagen. Other pain inhibiting<br />

effects are also present in PRP matrix grafts<br />

which allow earlier resumption of pain free<br />

activity. It is the author’s experiences that these<br />

grafts, along with other regenerative grafting<br />

options, are at times the only viable treatment<br />

option for a select group of patients with<br />

degenerative myofascial tissue injuries. The<br />

authors re<strong>com</strong>mend appropriate first line<br />

therapies such as relative rest, appropriate<br />

bracing and kinesiotaping, evaluation of kinetic<br />

chain mechanics, and physical therapy with or<br />

without eccentric loading protocols be utilized<br />

prior to the use of these PRP matrix grafting<br />

protocols.<br />

Reduction in pain after PRP applications has<br />

been observed by several authors. However, an<br />

explanation of this phenomena has not always<br />

been given. The authors believe that serotonin<br />

released from activated platelets might be<br />

responsible for decreased pain, as described by<br />

Everts and Fanning. Except for the growth<br />

factors in the Alpha-granules, large amounts of<br />

serotonin are contained within the dense platelet<br />

granules. Since platelet counts of the PRP are<br />

generally almost six fold higher, when <strong>com</strong>pared<br />

to whole blood levels, serotonin levels are<br />

therefore also significantly increased at the<br />

wound site. This phenomena has been explained<br />

in detail by, Sprott et al. who reported on pain<br />

reduction following acupuncture and measured a<br />

decrease in serotonin concentration in platelets<br />

from these patients and an increase in serotonin<br />

levels in plasma, suggesting normalization of<br />

plasma serotonin levels due to the mobilization of<br />

platelet serotonin.<br />

26<br />

The use of PRP in tendinopaties in regenerative,<br />

musculoskeletal, medicine still needs to find it’s<br />

place, and we should be aware not to find a<br />

disease that can be healed by PRP, but perform<br />

solid evidence base studies to prove the right<br />

directions for use, efficacy, and costs benefits.<br />

Affiliation:<br />

The Da Vinci Clinic in Geldrop, The Netherlands,<br />

is an expert center for tissue regeneration and<br />

hyperbaric medicine.<br />

Email: everts@me.<strong>com</strong>


David Palmer, EdD, CCP, LP<br />

Jefferson Regional Medical Center’s<br />

Experience Using the Viper <strong>Perfusion</strong><br />

Charting System<br />

Abstract:<br />

Advantages associated with utilizing electronic<br />

medical records for perfusion charting include<br />

patient care documentation, research and quality<br />

improvement. Enhanced ability for ongoing<br />

perfusion practice modification is a key attribute<br />

leading to improved patient out<strong>com</strong>es. The<br />

electronic medical record (EMR) provides the<br />

opportunity for the average perfusion department<br />

to improve the quality of care and patient safety.<br />

An EMR can decrease charting time and charting<br />

errors providing increased productivity along with<br />

reduction of medical errors. <strong>Perfusion</strong> leadership<br />

requires a prerequisite of IT knowledge about<br />

<strong>com</strong>puters to implement and manage this<br />

challenge since EMR can have a difficult learning<br />

curve. <strong>Perfusion</strong>ists are also faced with learning<br />

another practice associated with quality<br />

assurance realities and the approach used to<br />

implement these new perspectives can impact<br />

the perfusion team. Our department offers an<br />

exception to some negative IT assumptions while<br />

positively challenging perfusion paradigms.<br />

Jefferson Regional Medical Center’s experience<br />

implanting the Spectrum Medical electronic chart<br />

and quality assurance plan into our normal<br />

perfusion routine represents a story <strong>com</strong>mon to<br />

most national perfusion departments. This<br />

discussion will focus on our early efforts<br />

justifying, implementing and integrating the<br />

system into our perfusion practice.<br />

Biography:<br />

David Palmer received an undergraduate degree<br />

in biology and master’s degree in educational<br />

leadership from Carlow University in Pittsburgh.<br />

His Doctorate is in Education from Duquesne<br />

University in Pittsburgh. He is a graduate from<br />

Shadyside Hospital’s School of <strong>Perfusion</strong> and is<br />

27


employed by Procirca, an affiliate of the<br />

University of Pittsburgh Medical Center. David<br />

volunteers as a paramedic in his <strong>com</strong>munity and<br />

serves with the ABCP, AC-PE and CAAHEP as a<br />

Board member. David and his wife Alane, who is<br />

also a perfusionist, live just outside the city of<br />

Pittsburgh in Green Tree with their three children<br />

and dog Penny.<br />

Affiliation:<br />

University of Pittsburgh Medical Center<br />

200 Lothrop Street<br />

Pittsburgh, PA 15213-2582<br />

Email: palmerda@upmc.edu<br />

28


Al Stammers, MSA, CCP, CPBMT<br />

Blood Sweat and Fears: Hemostasis<br />

Management Techniques during Cardiac<br />

Surgery<br />

As long as there has been extracorporeal flow<br />

there has existed a need to understand the<br />

various influences that affect hemostatic<br />

imbalance. Indeed, the pathophysiologic<br />

consequences of uncontrolled coagulation have<br />

been the nemesis for both thrombotic and<br />

hemorrhagic disorders. Cardiovascular disease<br />

often results from imbalances in both<br />

procoagulant and anticoagulant forces, and the<br />

conduct of extracorporeal circulation results in<br />

the disruption of protein derived coagulation<br />

systems as well as, and concentration and<br />

function of circulating thrombocytes. The<br />

endothelial lining also plays a key role in<br />

maintaining key hemostatic balances. The cross<br />

talk between hemostasis and coagulation is seen<br />

by the interconnected relationship between these<br />

two diverse, yet linked, phenomena.<br />

Cardiac surgery with cardiopulmonary bypass<br />

(CPB) has been ground zero for studying<br />

hemostatic imbalances. The majority of surveys<br />

on safety and CPB have identified bleeding and<br />

coagulation disturbances as the number one<br />

incident associated with its application. This has<br />

resulted in the publication of numerous<br />

systematic reviews on various techniques utilized<br />

to diminish the consequences of excessive<br />

haemorrhage while limiting patient exposure to<br />

allogeneic blood products and judiciously<br />

administering costly pharmaceutical agents. The<br />

incorporation of methodologies based upon<br />

utilizing the best available evidence and<br />

<strong>com</strong>parative effectiveness has refocused<br />

strategies for blood conservation. Indeed, an<br />

entire discipline has emerged dedicated to<br />

improving the knowledge of blood management<br />

29<br />

that has transcended into multiple surgical and<br />

medical clinical situations.<br />

Perhaps nowhere else in medicine does such a<br />

critical evaluation of the forces impacting the<br />

development and clot stabilization exist. The<br />

ability to easily quantify the effects of<br />

interventions by measuring blood loss, blood<br />

product infusion and resource consumption<br />

creates a touchstone for measuring interventions.<br />

This has necessitated a continued evaluation of<br />

the methods that are incorporated in blood<br />

conservation. Each center performing cardiac<br />

surgery with CPB is uniquely able to assess the<br />

efficacy of interventions at a fundamental level.<br />

The incorporation of information technology and<br />

the expansion of the electronic medical record in<br />

hospitals will serve as an effective tool to quantify<br />

performance and benchmark local results to<br />

regional and national data.<br />

Research on the effectiveness of interventions<br />

that make up a <strong>com</strong>prehensive blood<br />

management program are often hindered by the<br />

<strong>com</strong>plexities of variable-to-variable interactions<br />

that may obscure subtle benefits, and hence,


under emphasize contributions that occur<br />

through amalgamation. The present report will<br />

review the results obtained from formalizing<br />

blood management techniques at a regional<br />

medical center.<br />

Comprehensive Patient Blood Management<br />

<strong>Program</strong> at Geisinger Health Systems<br />

1. Preoperative Management<br />

a. Preoperative Blood Management<br />

Services<br />

b. Anemia Correction<br />

c. Pharmacologic Control<br />

2. Intraoperative Management<br />

a. Transfusion Algorithms<br />

i. Preoperative Coagulation<br />

Assessment<br />

ii. Microvascular Bleeding<br />

Protocols<br />

iii. Long Term Assist<br />

Management<br />

b. Coagulation Assessment using<br />

Point-of-Care Devices<br />

c. Cross Discipline Volemic Control<br />

d. CPB Circuit Configuration and<br />

Management<br />

i. Oxygenator<br />

ii. Cardioplegia<br />

iii. Intraoperative<br />

Autotransfusion<br />

iv. Ultrafiltration<br />

e. Autologous Priming<br />

f. Plasmapheresis with Platelet<br />

Concentration<br />

g. Utilization of Anticoagulants and<br />

Procoagulants<br />

h. Placement of Autotransfusion<br />

Devices in Obstetrics<br />

3. Postoperative Management<br />

a. Mediastinal Blood Collection and<br />

Postoperative Autotransfusion<br />

b. Utilization of Procoagulants<br />

Select Reference List<br />

1. Yazer MH, Waters JH. How do I<br />

implement a hospital-based blood<br />

management program? Transfusion Nov<br />

21, 2011 [Epub ahead of print].<br />

2. Geisinger Health Systems Blood<br />

Conservation <strong>Program</strong>s.<br />

http://www.geisinger.org/services/blood_c<br />

ons/<br />

3. Ganter, MT, Spahn DR. Active,<br />

personalized, and balanced coagulation<br />

management saves lives in patients with<br />

massive bleeding. Anesthesiology 2010;<br />

113:1016–8.<br />

4. Levy JH, Tanaka KA. The anticoagulated<br />

patient: Strategies for effective blood loss<br />

management. Surgery 2007;142:S71-S77.<br />

5. Moskowitz DM, McCullough JN, Shander<br />

A, et al. The impact of blood conservation<br />

on out<strong>com</strong>es in cardiac surgery: Is it safe<br />

and effective? Ann Thorac Surg<br />

2010;90:451–9.<br />

6. Goodnough, LT, Shander A. Blood<br />

management. Arch Pathol Lab Med.<br />

2007;131:695–701.<br />

30


7. Rivera JJJ, Iribarren JL, Raya JM, et al.<br />

Factors associated with excessive<br />

bleeding in cardiopulmonary bypass<br />

patients: a nested case-control study. J<br />

Cardiothorac Surg 2007:2;1-7.<br />

McGill N, O'Shaughnessy D, Pickering R, et al.<br />

Mechanical methods of reducing blood<br />

transfusion in cardiac surgery: randomised<br />

controlled trial. British Medical<br />

31


Susan Englert, RN, CCP, CPBMT<br />

Blood Management: Tug of War<br />

Blood Conservation modalities will be discussed<br />

and identified through literature review and<br />

ethical issues. Areas for improvement will be<br />

reviewed through the multidisciplinary players.<br />

The future of blood management will be<br />

discussed through the changing paradigm and<br />

identifying blood management champions in your<br />

facilities with take home messages.<br />

Affiliation:<br />

Susan J. Englert, RN, CNOR, CPBMT, CCP<br />

Chief <strong>Perfusion</strong>ist<br />

<strong>Perfusion</strong>.<strong>com</strong><br />

Florida Hospital Waterman<br />

1000 Waterman Way<br />

Tavares, Florida 32778<br />

Office 352-253-3333 ext 6715<br />

sjenglert12@gmail.<strong>com</strong><br />

sjenglert@perfusion.<strong>com</strong><br />

32


Peter Everts, PhD<br />

The Synergy of PRP & Fat Tissue in<br />

Reconstructive Surgery<br />

Abstract:<br />

Tissue repair at wound sites begins with clot<br />

formation, and subsequently platelet<br />

degranulation with the release of platelet growth<br />

factors, which are necessary and well-regulated<br />

processes to achieve wound healing. Plateletderived<br />

growth factors are biologically active<br />

substances that enhance tissue repair<br />

mechanisms, such as chemotaxis, cell<br />

proliferation, angiogenesis, extracellular matrix<br />

deposition, and remodeling. This review<br />

describes the biological background and results<br />

on the topical use of autologous platelet-rich<br />

plasma and platelet gel in gynecologic, cardiac,<br />

and general surgical procedures, including<br />

chronic wound management and soft-tissue<br />

injuries.<br />

Affiliation:<br />

The Da Vinci Clinic in Geldrop, The Netherlands,<br />

is an expert center for tissue regeneration and<br />

hyperbaric medicine.<br />

Email: everts@me.<strong>com</strong><br />

33


Dr. Paul DiGiorgi, MD, FACS<br />

<strong>Perfusion</strong> Pearls in Minimally Invasive<br />

Cardiac Surgery<br />

Abstract:<br />

Minimally invasive cardiac surgery introduces<br />

several advantages for patients but new<br />

challenges can arise requiring careful planning to<br />

optimize out<strong>com</strong>es.<br />

Case scenarios will be discussed focusing on<br />

similarities and differences between minimally<br />

invasive and standard sternotomy approaches to<br />

cardiac surgery. Technical as well as<br />

<strong>com</strong>municative factors will be discussed.<br />

Biography:<br />

Medical School: NYU School of Medicine,<br />

General Surgery Training: University of<br />

Connecticut, Cardiothoracic Research Fellow:<br />

Columbia University, Cardiothoracic Fellowship:<br />

NYU Medical Center<br />

34


Jeffrey Travis, MD, FACS & Ty Walker, CCP<br />

Eat More Chicken<br />

Introduction:<br />

a case that was presented to our group of a rare<br />

allergy of both beef and pork. The reason for<br />

consultation was aortic stenosis and coronary<br />

artery disease. The patient presents with<br />

cutaneous rash, hives and develops itching after<br />

several hours post ingestion of either beef or<br />

pork. He described one incident of massive<br />

swelling of the hands and throat, making it<br />

difficult to breathe. In general, this is a very<br />

active, well-developed 65 year old white male<br />

with no apparent distress. The patient has had a<br />

known murmur for quite some time. A recent<br />

echo revealed severe aortic stenosis which was<br />

confirmed with catheterization. The cath showed<br />

a valve area of 0.5 cm and a gradient of 67<br />

mmHg and also a 70% LAD and 70% OMI<br />

occlusion of the coronary arteries.<br />

Methods / Case Report:<br />

After reviewing the literature we found an actual<br />

article in the Journal of Thoracic and<br />

Cardiovascular Surgery “Heparin Allergy:<br />

Successful Desensitization for Cardiopulmonary<br />

Bypass”. This protocol uses a six day<br />

desensitization strategy with cautious<br />

intravenous doses of heparin, increased each<br />

day. Once reviewed, and with direction from our<br />

Chief of Cardiovascular Surgery, we proceeded<br />

with this therapy and course of action. We felt<br />

this was a safe choice for the patient and would<br />

answer questions such as can we desensitize the<br />

patient over time. Also, by monitoring platelet<br />

counts, we can rule out the possibility of HIT.<br />

Results / Discussion:<br />

With a successful and slightly altered treatment<br />

35<br />

therapy course, we ruled out an allergy to<br />

heparin and heparin-induced thrombocytopenia.<br />

Cardiac surgery was scheduled and performed in<br />

a routine fashion with no alteration in<br />

anticoagulation strategy. A mechanical aortic<br />

valve was placed, LIMA to LAD, and saphenous<br />

vein to OMI was performed. Benedryl was given<br />

as an added precautionary measure after<br />

induction. The patient was extubated the same<br />

day and up and talking the morning after surgery.<br />

Conclusion:<br />

This unique case provided a leading example of<br />

a team approach to patient care and superior<br />

patient out<strong>com</strong>es. I would like to personally thank<br />

our Chief of Cardiac Surgery for his passion and<br />

team approach in patient care and a key leader<br />

in our Blood Management <strong>Program</strong>.<br />

Affiliation:<br />

Lexington Cardiovascular Surgery


Biography:<br />

Born and raised in SC. Undergrad at Clemson,<br />

MD from USC. General surgery and Thoracic<br />

surgery at Wake Forest University. Partner<br />

Columbus Cardiovascular Surgery 6.5 years.<br />

Just Starting heart program at Lexington Medical<br />

Center<br />

36


Dr. Charles Roberts<br />

CABG in the Setting of Carotid Stenosis: How<br />

to Avoid Stroke<br />

Brief Biography<br />

Charles Stewart Roberts, MD, was born in<br />

Washington, D.C., in 1960, and educated at<br />

Vanderbilt (B.A., 1981) and Emory (M.D., 1986)<br />

universities. He had general surgical training at<br />

Barnes Hospital in St. Louis, and at the Medical<br />

University of South Carolina in Charleston,<br />

separated by two years in cardiovascular<br />

research in the Surgery Branch of the National<br />

Heart, Lung, and Blood Institute of the National<br />

Institutes of Health in Bethesda (1988-90). He<br />

<strong>com</strong>pleted a three-year fellowship in<br />

cardiothoracic surgery at the University of North<br />

Carolina in Chapel Hill in 1996, followed by one<br />

year in pediatric and adult cardiac surgery at the<br />

Royal Brompton Hospital in London.<br />

In 1997 he was appointed Assistant Professor of<br />

Surgery at the University of North Carolina,<br />

where his practice consisted of pediatric and<br />

adult cardiac surgery. In 2001 he went to<br />

Winchester Medical Center (Valley Health<br />

System) in Winchester, Virginia, where he has<br />

been Chief of Thoracic and Cardiovascular<br />

Surgery since 2004. His main interests are<br />

coronary and carotid atherosclerosis and valvular<br />

heart disease, and his practice consists of<br />

roughly 300 cardiovascular operations a year.<br />

Dr. Roberts has had three books published. The<br />

first, An Olive Branch for the Conquered<br />

(1990), is a collection of previously published<br />

poems. The second is a biography of his<br />

grandfather, Life and Writings of Stewart R.<br />

Roberts, MD: Georgia’s First Heart Specialist<br />

(1993), who was president of the Southern<br />

Medical Association in 1924 and the American<br />

Heart Association in 1933-4. The third book,<br />

Stoking the Fire: A Surgical Memoir of<br />

London (1999), describes his fellowship year<br />

with Mr. Christopher Lincoln, a distinguished<br />

cardiac surgeon.<br />

Dr. Roberts is author or co-author of some 80<br />

medical publications, the majority concerning<br />

cardiovascular disease. Singular editorials<br />

include one titled, “Postoperative Drug Therapy<br />

to Extend Survival After Coronary Artery Bypass<br />

Grafting” (Ann Thorac Surg 2000: 60; 1315-6),<br />

and another titled, “Cardiovascular Surgery as a<br />

Single Specialty: The Case to Unify Cardiac and<br />

37


Vascular Surgery” (J Thorac Cardiovasc Surg<br />

2008: 136; 267-70), two causes in which he<br />

believes. Medical history is a related interest and<br />

Dr. Roberts has presented at several annual<br />

meetings of the American Osler Society, of which<br />

he is a member.<br />

38


Robin Zappacosta, RN<br />

The Time is Right & Size Matters<br />

Abstract:<br />

Intra-aortic balloon pump (IABP) therapy is a<br />

proven treatment in the stabilization of severely<br />

<strong>com</strong>promised cardiac patients. The effects of<br />

providing increased myocardial oxygen supply,<br />

while also decreasing myocardial oxygen<br />

consumption, are well documented. The<br />

effectiveness of counterpulsation therapy is<br />

dependent on optimal volume displacement,<br />

synchronized within the cardiac cycle.<br />

Objectives:<br />

1. identify a method of improving<br />

timing in an irregular cardiac<br />

rhythm<br />

2. explore alternative methods of<br />

evaluating effectiveness of<br />

therapy<br />

3. discuss the effects of<br />

augmentation and challenges<br />

to optimal augmentation<br />

Affiliation:<br />

Global Clinical Sales Manager<br />

Teleflex Cardiac Care<br />

39


Saturday, February 18 th , 2012<br />

Blood Management & New Technology Sessions<br />

Moderator-Ty Walker<br />

Dennis Borne<br />

Medical Malpractice Insurance & the<br />

<strong>Perfusion</strong>ist<br />

Abstract:<br />

Definition of Medical Malpractice Insurance.<br />

Components to Policy<br />

<strong>Perfusion</strong>ist's need for Product<br />

Methods / Case Report:<br />

MedPlus' involvement in <strong>Perfusion</strong> market<br />

Texas Department of Insurance<br />

Texas Heart Institute<br />

Results / Discussion:<br />

Available Markets and Products<br />

Reason for Shortage of Markets<br />

Conclusion:<br />

Future of <strong>Perfusion</strong> Insurance<br />

What to look for in a policy<br />

Risk Retention Group<br />

Affiliation:<br />

President, Medical Professional Liability<br />

Underwriting Solutions, LLC (MedPlus, LLC)<br />

9555 W. Sam Houston Pkwy, STe 475<br />

Houston, TX 77099<br />

Email: dennis@medplusllc.<strong>com</strong><br />

40


Jeffrey Travis, MD, FACS<br />

Use of a TEG in Cardiac Surgery<br />

Abstract:<br />

TEG is a powerful tool in the use of blood<br />

management. In this presentation, we outline all<br />

the settings we have found it to be clinically<br />

useful in a <strong>com</strong>munity hospital setting.<br />

Methods / Case Report:<br />

We have recently introduced blood management<br />

into our hospital. The TEG has had the most<br />

broad reaching effect of any strategy employed<br />

to date.<br />

Conclusion:<br />

The TEG is a point of care test that delivers vital<br />

information to the practicing clinician that aids in<br />

reducing blood product usage and resources.<br />

Affiliation:<br />

Lexington Cardiovascular Surgery<br />

Email:jtravis007@charter.net<br />

Biography:<br />

Born and raised in SC. Undergrad at Clemson,<br />

MD from USC. General surgery and Thoracic<br />

surgery at Wake Forest University. Partner<br />

Columbus Cardiovascular Surgery 6.5 years.<br />

Just Starting heart program at Lexington Medical<br />

Center<br />

41


Dr. James Lonquist, MD, FACS<br />

Keynote Address:<br />

How to Succeed in Blood Management<br />

Abstract:<br />

Blood Management is a multi-disciplinary<br />

process designed to promote the optimal use of<br />

blood products. Cardiac surgery is uniquely<br />

positioned to play a leadership role in the<br />

implementation of a hospital wide blood<br />

management effort. An effective program<br />

en<strong>com</strong>passes preoperative optimization,<br />

intraoperative conservation measures, and<br />

careful postoperative management.<br />

Communication and alignment with the blood<br />

bank, laboratory, information technology, nursing,<br />

and hospital administration all contribute to the<br />

success of the program. Increasing awareness<br />

of transfusion risks has resulted in a more<br />

restrictive approach to transfusion triggers over<br />

the past decade. Education of health care<br />

practitioners in the current evidence based<br />

guidelines plays a vital part in changing<br />

transfusion practices. The ultimate goal is to<br />

ensure safe and appropriate use of blood<br />

resources.<br />

42


Al Stammers, MSA, CCP, CPBMT<br />

ProvenCare Medicine: A Primer for Future<br />

Health Care Delivery Models<br />

Introduction<br />

Health care delivery is a <strong>com</strong>plex process that<br />

utilizes sophisticated integrated technologies to<br />

provide society with a safe and reproducible<br />

system of medical management. Its delivery is<br />

intimately tethered by economic constraints<br />

which have been emphasized in the United<br />

States when the Patient Protection and<br />

Affordable Care Act was signed into law by<br />

President Barack Obama on March 23, 2010.<br />

Although there are numerous factors that<br />

influence how health care is delivered there is an<br />

inherent expectation that patients will receive the<br />

right care at the right time using the best<br />

techniques so that out<strong>com</strong>e is related to the<br />

severity of the illness, more so then the process<br />

of how it is delivered. Although intuitive in nature<br />

this has not been shown to be how care is<br />

delivered in America. Clearly an evolving health<br />

environment has established mandates for<br />

change across the entire system that involves<br />

and affects the providers, payors and patients.<br />

Geisinger Health Systems (GHS) has undertaken<br />

an innovative approach to dealing with this<br />

changing health care environment. This system<br />

redesign began six years ago starting with<br />

cardiac surgery, and has since be<strong>com</strong>e an<br />

integral philosophy that has been engrained as<br />

the foundation for care across GHS.<br />

The Geisinger System<br />

Founded in 1915, GHS is an integrated delivery<br />

system (IDS) located in central northeastern<br />

Pennsylvania that serves 43 rural counties and<br />

over 2.6 million residents. This area of<br />

Pennsylvania is known for its industrial<br />

development which occurred during the previous<br />

century because of the abundance of resources<br />

(anthracite coal, limestone, and iron ore)<br />

necessary for the production of steel. GHS is<br />

made up of three fully owned tertiary or<br />

quaternary inpatient facilities employing over<br />

14,000, including 800 physicians at 60 sites. It is<br />

one of the largest non-medical school based<br />

graduate medical education systems in the<br />

country. The entire enterprise has been<br />

connected with an electronic health record (EHR)<br />

since 1995, which is used across all GHS<br />

entities. The EHR has provided the foundation for<br />

<strong>com</strong>prehensive longitudinal care across the IDS.<br />

43


As an IDS Geisinger owns its own managed care<br />

<strong>com</strong>pany termed the Geisinger Health Plan<br />

(GHP), which serves over 230,000 members. In<br />

addition to providing coverage to GHS providers<br />

it also contracts with over 18,000 non-employed<br />

physicians and 90 additional hospitals. It is rated<br />

the best private and best Medicare health plan in<br />

Pennsylvania and is ranked in the top five<br />

nationally 1 .<br />

ProvenCare<br />

In 2005 the GHS board of directors challenged<br />

senior leadership to reengineer the system under<br />

which care is delivered. The impetus for this drive<br />

was not entirely based upon improving out<strong>com</strong>es<br />

since the system had enjoyed good success<br />

under the current care delivery system. Instead it<br />

was a process designed to focus on innovation<br />

leading to targeted strategies such as care<br />

coordination and transitions, chronic care<br />

optimization, illness prevention through the<br />

engagement of patients, and a transformation of<br />

how acute episodic care is delivered. This was<br />

being done to enhance health care value while<br />

emphasizing individualized patient care.<br />

Accenting the preventative measures was a<br />

<strong>com</strong>mitment to improve diagnostic and treatment<br />

efforts employing the best available evidence.<br />

The reengineering of acute episodic care has<br />

been termed the ‘warranty’ because one of the<br />

basic tenets of this process is the proviso that if<br />

all the steps in the care plan were followed GHS<br />

would be financially responsible for any<br />

<strong>com</strong>plications that resulted within 90 days of<br />

1 http://www.ncqa.org/<br />

44<br />

surgery. Since it is impossible to reduce<br />

<strong>com</strong>plication rates to zero, the historical cost (2-<br />

year) of <strong>com</strong>plications could be calculated and<br />

added to the mean cost of the procedure that<br />

purchasers would pay up-front, but not be<br />

responsible for as in a traditional fee-for-service<br />

system.<br />

The initial patients were all enrolled in the GHP,<br />

which assured a continuum of care and served<br />

as the ‘sweet spot’ for the launch of the<br />

ProvenCare initiative. The cost of the procedure<br />

was a single-bundled payment mutually agreed<br />

upon using a risk-based pricing process where<br />

discounts would be given to either the provider or<br />

payor based upon historical results.<br />

The target care models that were identified as<br />

potentially benefiting from the ProvenCare<br />

methodology had the following characteristics:<br />

1. Large impact by patient population or<br />

resource consumption<br />

2. A significant amount unjustified variation<br />

3. Large amount of evidence based or<br />

consensus derived best practice<br />

guidelines<br />

4. Presence of out<strong>com</strong>e metrics and<br />

benchmarks<br />

5. High interest from clinical champions or<br />

consumers<br />

6. Those with observed out<strong>com</strong>es furthest<br />

from expected performance<br />

It was felt that the areas with the greatest impact<br />

would be those seen with the management of<br />

chronic disease states. Conditions such as


diabetes, congestive heart failure, chronic kidney<br />

disease, hypertension and coronary artery<br />

disease were all evaluated. The first application<br />

using the ProvenCare methodology was focused<br />

on acute episodic surgical care of patients<br />

presenting with coronary artery disease who<br />

underwent a coronary artery bypass graft<br />

(CABG) procedure, and was termed ProvenCare<br />

CABG.<br />

Proven CABG<br />

Geisinger’s cardiac surgery service line is<br />

distributed between two hospitals (Geisinger<br />

Medical Center - GMC, Danville, PA and<br />

Geisinger Wyoming Valley – GWV, Wilkes Barre,<br />

PA) separated by approximately 60 miles. There<br />

are six adult cardiac surgeons, one pediatric<br />

cardiac surgeon, and 8 perfusionists who provide<br />

service for both facilities. The 2010 total cardiac<br />

case number was 634 cases with 74% of them<br />

performed at the GMC facility.<br />

At GHS the surgical intervention for most patients<br />

presenting with coronary artery disease has been<br />

to use a beating heart, off-pump technique.<br />

Although out<strong>com</strong>es for patients treated with<br />

CABG had been excellent, the surgical team<br />

identified a number of idiosyncratic tendencies<br />

amongst surgeons with how patients were<br />

managed. Standardization of care was therefore,<br />

a critical element driving the reengineering<br />

process. The decision to standardize care<br />

delivery was agreed upon amongst all surgeons<br />

and a mechanism to accept a system wide<br />

approach utilizing guidelines determined through<br />

either an evidence-based best practice or<br />

consensus opinion approach, utilized. The 2004<br />

American College of Cardiology-American Heart<br />

Association Guidelines was chosen as the<br />

foundation for standardization. Each guideline<br />

was reviewed and further defined with<br />

measurable indicators for performance, as well<br />

as individuals identified who took overall<br />

responsibility. The group identified 20 adoptable<br />

guidelines with 40 separate elements of care.<br />

Patients were also required to sign a CABG<br />

Patient Compact outlining their <strong>com</strong>mitment to<br />

the ProvenCare model.<br />

Benchmarking results from the Society of<br />

Thoracic Surgeons Database served as the<br />

historical basis for performance and <strong>com</strong>pared to<br />

the results after the guidelines were<br />

implemented. Primary metrics for analysis<br />

included adherence to workflow guidelines and<br />

financial impact. PC patients were enrolled for<br />

one year (February 2007 through February 2007)<br />

and <strong>com</strong>pared to a conventional care (CC) group<br />

(operated upon in 2005).<br />

Results<br />

The program began in February 2006 and by<br />

August of that year 100% of all PC patients<br />

(n=117) received all 40 elements of care. When<br />

<strong>com</strong>pared to the CC group (n=137) there was a<br />

trend towards reduced adverse events in the PC<br />

group as <strong>com</strong>pared to CC. There was a<br />

reduction in hospital charges by 5% in the PC<br />

group as <strong>com</strong>pared to the CC group that most<br />

likely occurred by a drop in length-of-stay from<br />

6.3 to 5.3 days.<br />

45


physicians had an added incentive in the form of<br />

a financial bonus when all elements of care were<br />

provided. Insurance <strong>com</strong>panies and third party<br />

purchases would value the ‘warranty’ and share<br />

in a proactive fee structure that limited the costs<br />

for adverse events emphasizing the trend in<br />

health care reimbursement towards pay-for-<br />

Conventional Care<br />

(n=137)<br />

ProvenCare<br />

(n=117)<br />

N % N % P Value<br />

Blood Products Used 32 23.4 19 16.2 0.17<br />

Reintubated during hospital stay 4 2.9 1 0.9 0.38<br />

Operative <strong>com</strong>plication 8 5.8 5 4.3 0.78<br />

Infection: Sternum - Deep 1 0.7 1 0.9 1.00<br />

Neurologic <strong>com</strong>plication 2 1.5 1 0.9 1.00<br />

Pulmonary <strong>com</strong>plication 10 7.3 3 2.6 0.15<br />

Atrial fibrillation 31 22.6 30 25.6 0.58<br />

Any <strong>com</strong>plication STS Definition 53 39.0 41 35.0 0.55<br />

Postoperative LOS (median) 4 4 0.25<br />

Readmission to ICU 4 2.9 1 0.9 0.38<br />

Operative Mortality 2 1.5 0 0.0 0.50<br />

Discussion<br />

The underlying principle of the PC model is a<br />

strict adherence to either evidence-based or<br />

consensus reached guidelines would result in a<br />

consistency of care application assuring that<br />

patients receive the current best-medicine<br />

approach to acute episodic procedures such as<br />

cardiac surgery. For CABG surgery the<br />

performance. Most importantly patients would not<br />

be seen as passive participants in their care<br />

delivery but take an active role in their health<br />

management. The success of Proven Care<br />

CABG has led to its expansion in other service<br />

areas across the GHS, which include cataract<br />

surgery, hip replacement surgery, percutaneous<br />

coronary intervention and perinatal care.<br />

46


The utilization of PC methodology that<br />

incorporates an evidence-based or consensus<br />

reached guidelines for perfusion would<br />

standardize how perfusion care is delivered and<br />

result in a more consistent throughput of activity<br />

amongst staff. The perfusion EHR will provide<br />

the foundation by which data would be collected<br />

and analyzed to allow performance review.<br />

Variation from the clinical guidelines would<br />

remain the judgment of the clinician who<br />

assesses patient response avoiding the<br />

‘cookbook’ tendencies that develop by strict<br />

adherence to algorithmic principles.<br />

1. Eagle KA, Guyton RA, Davidoff R, et al.<br />

ACC/AHA 2004 Guideline Update for<br />

Coronary Artery Bypass Graft Surgery:<br />

Summary Article. Circulation.<br />

2004;110:1168-76.<br />

2. Casale AS, Paulus RA, Selna MJ, et al.<br />

"ProvenCareSM": a provider-driven payfor-performance<br />

program for acute<br />

episodic cardiac surgical care. Ann Surg.<br />

2007;246:613-21.<br />

3. Berry SA, Doll MC, McKinley KE, Casale<br />

AS, Bothe A Jr. ProvenCare: quality<br />

improvement model for designing highly<br />

reliable care in cardiac surgery. Qual Saf<br />

Health Care. 2009;18:360-8.<br />

4. Steele G Jr. Re-engineering systems of<br />

care: surgical leadership. J Am Coll Surg.<br />

2010;210:1-5.<br />

Affiliation<br />

Alfred H. Stammers, MSA, CCP, PBMT<br />

Director of <strong>Perfusion</strong> Services<br />

Geisinger Health System<br />

ahstammers@geisinger.edu<br />

Summary<br />

The critical elements for success of the<br />

ProvenCare model include a dedicated<br />

<strong>com</strong>mitted support from senior leadership and<br />

management; the engagement of clinical,<br />

administrative and financial stakeholders to<br />

agree to methodology; a precise identification of<br />

workflow processes to standardize delivery<br />

reengineered where necessary to over<strong>com</strong>e<br />

hurdles; and a <strong>com</strong>mitment from patients to<br />

engage in the care process.<br />

References<br />

47


Dr. Allen Heldman<br />

Transapical AVR in the Hybrid OR Setting<br />

Abstract:<br />

Alan W. Heldman, MD, FSCAI<br />

Professor of Medicine<br />

Cardiovascular Division<br />

Clinical Research Building<br />

1120 NW 14th Street, #1118<br />

Miami, FL 33136<br />

305-243-5138 Office<br />

305-243-1731 Fax<br />

University of Miami Miller School of Medicine<br />

48


John G. Rivera, B.S., M.A.<br />

Rethinking Blood Conservation; the Role of<br />

Autotransfusion<br />

Abstract:<br />

Blood is in short supply and the costs to collect,<br />

process, test, maintain and transfuse it will<br />

continue to grow. Some authors have noted that<br />

patients receiving allogeneic transfusions have<br />

more adverse out<strong>com</strong>es and longer lengths of<br />

stay than patients who do not receive donor<br />

blood. Insurance organizations are examining<br />

surgical out<strong>com</strong>es and have instituted a pay for<br />

performance mechanism for reimbursement.<br />

Consequently, these “never events” are not being<br />

reimbursed by the insurers and the hospitals are<br />

being forced to absorb those additional costs.<br />

In 2007 the Society of Thoracic Surgeons, in<br />

conjunction with the Society of Cardiovascular<br />

Anesthesia, issued practice guidelines for<br />

Perioperative Blood Transfusion and Blood<br />

Conservation in Cardiac Surgery. Multiple<br />

modalities were identified both in the<br />

preoperative and perioperative setting that would<br />

directly impact the practice of transfusion during<br />

cardiovascular surgery. The goal of these<br />

guidelines was to establish a consistent practice<br />

of transfusion during cardiovascular surgery that<br />

reflected the implementation of a written<br />

algorithm which relied upon multiple clinical<br />

factors including lower hemoglobin thresholds.<br />

Unfortunately, <strong>com</strong>pliance with these guidelines<br />

was limited and written updates in 2010 and<br />

2011 were created to take advantage of other<br />

modalities that were now available. Many<br />

clinicians have not reviewed these documents<br />

and have not fully <strong>com</strong>plied with these directives.<br />

The latest update to these Guidelines in 2011<br />

also identified clinical practices that were under<br />

the auspices of the perfusionists such as: smaller<br />

volume cardiopulmonary bypass circuits,<br />

specialized tubing coatings, the use of centrifugal<br />

pumps, advanced heparin management,<br />

retrograde autologous priming (RAP),<br />

hemodilution and autotransfusion.<br />

Saving blood makes sense for everyone involved<br />

in the practice of transfusion. The use of a<br />

restrictive allogeneic transfusion practice has<br />

directly resulted in improved patient out<strong>com</strong>es<br />

and lower treatment costs. A written transfusion<br />

algorithm that is followed explicitly in the<br />

49


perioperative and postoperative settings is a<br />

critical first step. The use of multiple modalities<br />

and evidenced based practices are well<br />

documented and indicated per the STS Meta<br />

analysis of 753 articles over a two (2) year time<br />

period. Validation of all practices, along with<br />

periodic quality control measurement, is<br />

mandated by the appropriate regulatory bodies<br />

including AABB.<br />

In addition to a limited blood supply, the direct<br />

costs to collect, test, process, store, monitor and<br />

transfuse blood can vary from $500 to $1,200.<br />

Hospital clinical performance is being reviewed<br />

by CMS and reimbursement may be lowered for<br />

poor performance. Several states are publishing<br />

these results in local newspapers and internet<br />

savvy patients are choosing hospitals and<br />

surgeons based upon this data. Unfortunately,<br />

patients are arriving at the hospital are in<br />

exceedingly poor clinical condition. This includes<br />

the ongoing use of anticoagulation and platelet<br />

inhibitor therapy. The number<br />

Rethinking Blood Conservation; the Role of<br />

Autotransfusion (continued)<br />

of high risk patients who are older males, obese,<br />

diabetics, smokers and having a history of<br />

previous surgery with blood transfusion is<br />

increasing as <strong>com</strong>pared to the same kind of<br />

cardiovascular surgery patients from 10 years<br />

ago. Many patients self medicate with nutritional<br />

supplements such as garlic, Gingko Biloba,<br />

ginseng, green tea, Red Yeast Rice, vitamin E,<br />

St. John’s Wort, and aspirin. These agents can<br />

cause resistance to anticoagulation therapies<br />

and inhibition of platelet function. The bottom<br />

line is that these “sicker” patients are subject to<br />

50<br />

significantly increased perioperative bleeding.<br />

Even the heparin anticoagulant being used in<br />

cardiovascular surgery is subject to variability.<br />

Autotransfusion is one of the primary modalities<br />

being re<strong>com</strong>mended to limit allogeneic<br />

transfusion. It is a relatively inexpensive<br />

procedure with tremendous flexibility. The<br />

process is safe, fast, efficient and easy to<br />

implement. Available autotransfusion devices<br />

are highly automated and can be rapidly<br />

implemented and deployed. Autotransfusion is<br />

the only transfusion alternative that is routinely<br />

accepted by Jehovah’s Witness patients.<br />

Validation and ongoing quality control of<br />

autotransfusion devices require direct oversight<br />

and testing in the laboratory setting. Written<br />

policies and procedures should be reviewed by<br />

the Laboratory Medical Director on an annual<br />

basis and operator <strong>com</strong>petencies need to be<br />

frequently validated. There must be a medical<br />

director responsible for the autotransfusion<br />

program.<br />

A wide variety of personnel are involved in the<br />

operation of autotransfusion devices. Although<br />

perfusion personnel are the primary operators of<br />

autotransfusion devices during cardiovascular<br />

surgery, other medical personnel are running<br />

these devices in non-cardiovascular cases.<br />

Anesthesia technologists and technicians,<br />

nurses, surgical technicians, medical<br />

technologist, respiratory therapists and other<br />

personnel regularly present in Operating Rooms<br />

are responsible for running autotransfusion<br />

machines. These personnel must <strong>com</strong>plete<br />

annual autotransfusion training and certification.<br />

The American Society of Extracorporeal<br />

Technology has created a standardized


autotransfusion testing program that can be<br />

<strong>com</strong>pleted on line in a proctored setting. Passing<br />

this test authorizes the participant to be<br />

credentialed as a Perioperative Blood<br />

Management Technologist (PBMT).<br />

In the hands of an appropriately trained and<br />

credentialed operator, autotransfusion generates<br />

safe and high quality washed packed red cells.<br />

The process of autotransfusion is fast and the<br />

patient benefit is immediate. Blood is literally<br />

being recycled and valuable allogeneic blood<br />

supplies are conserved for use for other patients<br />

who are not eligible for or are contraindicated for<br />

autotransfusion. Autotransfusion is a highly<br />

<strong>com</strong>plementary activity that helps to conserves<br />

the limited allogeneic blood supply.<br />

Bibliography<br />

Gorman-Koch, C, Liang, L, Duncan, A. I.,<br />

Mihaljevic, T, Cosgrove, DM, Loop, FD, Starr,<br />

NJ, Blackstone, EH. Morbidity and mortality risk<br />

associated with red blood cell and blood<strong>com</strong>ponent<br />

transfusion in isolated coronary artery<br />

bypass grafting. Critical Care Medicine<br />

2006;34,6:1608-1616<br />

Thoracic Surgeons and the Society of<br />

Cardiovascular Anesthesiologists clinical practice<br />

guidelines. Annals of Thoracic Surgery<br />

2007;835(5 Suppl):S27-86<br />

Ferraris, VA, et al. 2010 Update to the Society of<br />

Thoracic Surgeons Blood Conservation<br />

Guidelines<br />

Ferraris, VA, Brown, JR, Despotis, GJ, Hammon,<br />

JW, Reece, TB, Sibu, SP, Song, HK, Clough,<br />

ER, Shore-Lesserson, LJ, Goodnough, LT,<br />

Mazer, CD, Shander, A, Stafford-Smith, M,<br />

Waters, J, Baker, RA, Perf D, Dickinson, TA,<br />

Fitzgerald, DJ, Likosky, DS, Shann, KG. 2011<br />

Update to the Society of Cardiovascular<br />

Surgeons and the Society of Cardiovascular<br />

Anesthesiologists Blood Conservation Clinical<br />

Practice Guidelines. Annals of Thoracic Surgery<br />

2011;91:944-82<br />

Standards for Perioperative Autologous Blood<br />

Collection and Administration, 4 th Edition, AABB,<br />

2009<br />

Guidelines for Blood Recovery and Reinfusion in<br />

Surgery and Trauma, AABB, November 2010<br />

Shander, A, Hoffman, A, Ozawa, S, Theusinger,<br />

OM, Gombotz, H, Spahn, DR. Activity-based cost<br />

of Blood Transfusions in surgical patients at four<br />

hospitals. Transfusion 2010;50:753-765<br />

Ferraris, VA, Ferraris, SP, Saha, SP, Haan, CK,<br />

Royston, BD, Bridges, CR, Higgins, RSD,<br />

Despotis, GJ, Brown, JR, Speiss, BD, Shore-<br />

Lesserson, LJ, Stafford-Smith, M, Mazer, CD,<br />

Bennett-Guerrero, E, Hill, SE, Body, S.<br />

Perioperative Blood Transfusion and blood<br />

conservation in cardiac surgery: the Society of<br />

51


Gary Allen, MD, FACS<br />

How Low can We Go, the Attenuation of<br />

Heparin during OPCAB<br />

Abstract:<br />

Background: The optimum heparin dosing<br />

strategy for off-pump coronary artery bypass<br />

graft (OPCAB) surgery is not well described. A<br />

review of the literature shows<br />

Heparin dosages between 70 U/kg – 500 U/kg<br />

and corresponding activated clotting times (ACT)<br />

between 250 – 500 seconds (s). We<br />

hypothesized that an ACT of 200 s would provide<br />

satisfactory anticoagulation and possibly reduce<br />

peri-operative blood loss. To achieve our ACT<br />

goal we examined three different dosing<br />

formulas.<br />

Method: Twenty (estimated at this time)<br />

consecutive OPCAB patients were studied at a<br />

single institution. The HEPCON HMS (Medtronic<br />

Minneapolis, MN) in conjunction with the Heparin<br />

Dose Response (HDR) was used to derive<br />

heparin dosages. Dosing strategies were as<br />

follows: Formula 1. [heparin] to achieve ACT 200<br />

s x total blood volume (TBV), Formula 2 (1/3)<br />

[heparin] to achieve ACT 480 s x TBV , and<br />

Formula 3 [heparin] to achieve ACT 480 s.<br />

Protamine doses were calculated for full heparin<br />

reversal.<br />

Results: There were 11 males (55%) and 9<br />

females (45%). Mean age was 69 + 4.5 years.<br />

The mean number of grafts was 2.4 + 0.6.<br />

Patients with a history of coagulopathy were<br />

excluded. Mean anticoagulation data and<br />

standard error of the mean are presented<br />

52


In the table below:<br />

HEPARIN<br />

(UNITS)<br />

Calculated<br />

Additional<br />

ACT (S)<br />

Baseline<br />

Post<br />

heparin<br />

End of case<br />

PROTAMINE<br />

(U)<br />

Formula<br />

1<br />

Formula<br />

2<br />

Formula<br />

3<br />

Administered<br />

Dose<br />

A multiple-choice survey questionnaire was<br />

developed and electronically distributed within<br />

perfusion <strong>com</strong>munity in association with<br />

<strong>Perfusion</strong>.Com. Patients undergoing OPCAB<br />

procedures were assigned in a randomized<br />

fashion. The HEPCON HMS, targeted levels for<br />

ACT values and corresponding heparin<br />

strategies, results obtain with this device were<br />

used to develop the empirical formulas for<br />

attenuating heparins affects, in addition the<br />

HEPCON HMS is based on the maintenance of<br />

individually determined heparin levels.<br />

The HEPCON HMS in conjunction with the<br />

Heparin Dose Response (HDR) produced the<br />

parameters for the genesis of three different<br />

calculations/formulas. The first formula evolved<br />

based only on using one third of the total<br />

re<strong>com</strong>mended amount of heparin. The second<br />

formula was based on one third of the calculated<br />

heparin concentration in order to achieve an ACT<br />

of 480sec, multiplied by the patients total blood<br />

volume. The third formula en<strong>com</strong>passed the<br />

manipulation of the HEPCON HMS parameter,<br />

200sec replaced the original 480sec and the<br />

<strong>com</strong>putations were revised, reducing the heparin<br />

concentration significantly, it was also multiplied<br />

by the total blood volume. Each particular<br />

equation proposed a total amount of heparin for a<br />

given attenuation of anticoagulation. Based on<br />

our objectivity, our prior experience and the<br />

expectation of the calculated heparin dose, a<br />

total amount of heparin would be determined,<br />

respectively. In addition, we investigated the<br />

protamine dose that would be required to return<br />

to a normal hemostatic system and whether or<br />

not that should actually be administered,<br />

depended on the relative amount.<br />

Ht/cm Wt/kg TBV<br />

X = Heparin Concentration acquired to achieve<br />

480sec ACT<br />

Y = HEPCON HMS predicted Total Amount of<br />

Heparin<br />

Z = Heparin Concentration acquired to achieve<br />

200sec ACT, after established baseline with HDR<br />

53


1. Y divided by 3 = Total amount of Heparin<br />

2. 1/3 of X multiplied by TBV = Total amount<br />

of Heparin<br />

3. Z multiplied by TBV = Total amount of<br />

Heparin<br />

54


Susan Englert, RN, CCP, CPBMT<br />

Patient Safety Issues: Leave Your Ego Out of<br />

the Room<br />

Abstract:<br />

Important identifiers promoting patient safety and<br />

preventing <strong>com</strong>plications will be discussed. The<br />

importance of high reliability clinical teamwork<br />

and decreasing risk will be stressed as key<br />

<strong>com</strong>ponents. I will be reviewing out<strong>com</strong>es to<br />

produce a better, safer, patient care and a better<br />

experience of care for patients. Team factors<br />

and a safety pyramid will be identified through<br />

teamwork climate and trust.<br />

Affiliation:<br />

Susan J. Englert, RN, CNOR, CPBMT, CCP<br />

Chief <strong>Perfusion</strong>ist<br />

<strong>Perfusion</strong>.<strong>com</strong><br />

Florida Hospital Waterman<br />

1000 Waterman Way<br />

Tavares, Florida 32778<br />

Office 352-253-3333 ext 6715<br />

sjenglert12@gmail.<strong>com</strong><br />

sjenglert@perfusion.<strong>com</strong><br />

55


Ty Walker, CCP<br />

Simulation Stimulation<br />

Abstract:<br />

<strong>Perfusion</strong>.<strong>com</strong> takes great pride in the<br />

continuous development & education of its<br />

<strong>Perfusion</strong>ist & PBMT’s.<br />

One of the requirements of our organization is to<br />

have documented monthly meetings. These<br />

monthly meetings give us an excellent<br />

opportunity to go over one situational event that<br />

could potentially affect all of us in our practice.<br />

These events could be structured to be<br />

simulations in the OR, or verbal discussions on<br />

treatments for patients with certain diagnosis’.<br />

The goal would be constant stimulation of our<br />

thought process, a structured team approach,<br />

and continuous continuity of care.<br />

What a better opportunity to continually raise the<br />

bar and set standards which are superior to other<br />

perfusion corporations. Each month we will<br />

supply our group with a topic of discussion.<br />

56


Breakfast &<br />

Lunch<br />

With<br />

Vendors<br />

57


THURSDAY<br />

Sorin – Breakfast 0700-0800; Presenter Ty Walker, CCP, CPBMT<br />

Nonin – Lunch 1130-1230; Presenter Ty Walker, CCP, CPBMT<br />

FRIDAY<br />

Cytomedix – Breakfast 0700-0800 Presenter Al Stammers, MSA, CCP,<br />

CPBMT<br />

Covidien – Lunch 1130-1230; Presenter TBD<br />

SATURDAY<br />

Hospira – Breakfast 0700-0800; Presenter Dr. Richard Juda<br />

Haemonetics – Lunch 1130-1230; Presenter Mike Miller<br />

58


Al Stammers, MSA, CCP, CPBMT<br />

An Update on Autologous Platelet-Gel:<br />

Results from Our First 7,000 Procedures<br />

No idea is so outlandish that it should not be<br />

considered with a searching but at the same time<br />

a steady eye.<br />

Winston Churchill<br />

A person with a new idea is a crank until the idea<br />

succeeds.<br />

Mark Twain<br />

Few areas of blood management have been<br />

simultaneously so widely revered yet broadly<br />

questioned as the process of autologous platelet<br />

gel (APG). An equal balance of skepticism<br />

tempers the degree of enthusiasm where a<br />

believer’s passion is only surpassed by a critic’s<br />

admonitions. APG is described as the process of<br />

harvesting one’s own cells (platelets),<br />

concentrating them, exposing them to an agonist,<br />

activating them to release their intrinsic<br />

substances, and applying them to an area of the<br />

body in need of healing. Its growth over the past<br />

decade can best be described as geographically<br />

variant where certain locations have seen<br />

explosive growth while others have seen little to<br />

no acceptance. It is clearly a technology in<br />

search of a science, which suffers from the<br />

conventional wisdom of a lack of evidence-base.<br />

Its origins can be traced to the techniques of<br />

intraoperative plasmapheresis.<br />

Although the process of plasmapheresis has<br />

been in clinical use for over 50 years, its<br />

application as a perioperative clinical tool was not<br />

59<br />

appreciated until the mid 1970’s. Initial research<br />

focused on the separation of autologous whole<br />

blood into fractions that could be administered<br />

throughout the surgical procedure. In cardiac<br />

surgery this technique became popular in the late<br />

1980’s, but controversy surrounding its<br />

reproducible efficacy led to its decline in the late<br />

1990’s. Although a number of studies promoted<br />

the benefits of plasmapheresis as a blood<br />

conservation measure, an equal number failed to<br />

show a reduction in allogeneic blood product<br />

utilization.<br />

During the past two decades, however, this<br />

technique has reemerged not based upon its<br />

original potential to improve hemostasis, but<br />

instead related to the contribution of the platelet<br />

and its biological affect on wound healing. A<br />

secondary benefit of this process, and one that<br />

has promoted its popularity is the derivation of<br />

the product from an autologous source. It is


harvested from the same individual to whom it<br />

will be applied. The growth of APG has occurred<br />

most rapidly during the past decade both in the<br />

United States and across Europe and is<br />

beginning to expand in Asia. What makes APG<br />

so attractive is the ease of which the platelets<br />

can be harvested using point-of-care devices that<br />

are utilized both in clinics and physician offices<br />

as well as throughout operating theaters. The<br />

technique for making APG begins with a modified<br />

plasmapheresis procedure that yields a plateletrich<br />

plasma (PRP) fraction either by a<br />

centrifugation procedure or through the process<br />

of ultrafiltration (the former being the most<br />

utilized technique). Once the platelets are<br />

harvested they are activated and degrannulate<br />

releasing various intrinsic proteins primarily by<br />

exocytosis from alpha granules. The PRP<br />

fraction usually has a platelet count of 4 to 6<br />

times that found in the unfractionated sample<br />

with a normal concentration of fibrinogen. Hence,<br />

APG can also be termed fibrin-platelet gel as a<br />

result of <strong>com</strong>bining coagulation with cellular<br />

activation. Since white cells are retained as well<br />

some have coined the term platelet-richleukocyte<br />

plasma. The following review is not<br />

intended to be neither <strong>com</strong>prehensive nor<br />

inclusive and readers are directed elsewhere for<br />

a more in-depth evaluation, but instead to<br />

address several major clinical applications and<br />

controversies surrounding the use of APG in<br />

surgery.<br />

Clinical Applications<br />

One of the most attractive facets of APG is its<br />

broad applicability for improving wound healing<br />

across a diverse population of patients.<br />

Estimates of its yearly potential use range into<br />

the hundreds of thousands of patients in the<br />

United States alone 2 . However, the majority of<br />

cases reported thus far in the literature have<br />

been focused on three main areas: dermatology,<br />

orthopedics and maxofacillary surgery. Other<br />

developing services that have reported on its use<br />

include cardiac surgery and plastic surgery.<br />

Autologous Platelet Gel Use at Geisinger<br />

Health System<br />

We began using the techniques of APG in 2002<br />

with total figures for one of our hospitals shown in<br />

Figure 1. From 2002 through December 2011 we<br />

performed over 7,000 procedures where AGF<br />

were applied. This represents various specialties<br />

with the preponderance clustered in orthopedic<br />

and cardiac and surgery. Within orthopedics we<br />

began our experience with APG spine surgery<br />

but have since shifted to the use of autologous<br />

stem cells for spinal fusions. Presently the<br />

majority of our orthopedic cases involve<br />

regenerative injection therapy for rotator cuff and<br />

shoulder surgeries (52.1% of non-cardiac cases<br />

performed in 2008) followed by its use in anterior<br />

cruciate ligament surgery (18.3% of non-cardiac<br />

cases performed in 2008). APG is also applied<br />

for non-union and tendon surgeries although to a<br />

lesser degree (5.3% of non-cardiac cases<br />

performed in 2008). 70% of these procedures<br />

are performed in an outpatient basis with patients<br />

60<br />

2 Personal <strong>com</strong>munications with Harvest Technologies,<br />

Plymouth, MA, USA


eceiving this therapy for same-day surgery.<br />

More recently we have expanded our application<br />

of this technique in the area of wound<br />

management for non-healing wounds.<br />

We examined the effects of APG on infection rate<br />

in cardiac surgical patients and reviewed<br />

consecutive cardiac surgical patients. Of the<br />

2,259 patients reviewed 382 had received APG<br />

applied to all surgical incisions <strong>com</strong>bined with a<br />

mixture of 10% calcium chloride (5mL) and<br />

bovine thrombin (5,000 units). The incidence of<br />

superficial infection was significantly lower in the<br />

APG group (n=0.3%) versus either a historical<br />

group of 929 patients (1.5%) and a concurrent<br />

group of patients (n=948) who did not receive<br />

APG (1.8%), p


may yield a platelet concentrate of up to 10 times<br />

the initial baseline level. During processing,<br />

anticoagulated whole blood is automatically<br />

separated into red blood cells and plasma. The<br />

plasma along with the upper portion of the buffy<br />

coat layer are decanted into separate collection<br />

devices- a reservoir for platelet poor plasma<br />

(PPP) and a syringe for platelet rich plasma<br />

(PRP). Typically 3 to 10 mL of PRP provides a<br />

sufficient volume of material for various<br />

applications.<br />

Conclusion<br />

The use of APG has had a gradual and subdued<br />

penetration as a clinical modality to enhance<br />

wound healing. This tempered acceptance has<br />

its foundation linked to the paucity of strong<br />

evidence for its expansion, and although used in<br />

centers throughout the world, is most often linked<br />

to individual perceived notion of benefit. Its<br />

growth, or decline, will most assuredly be linked<br />

to the appearance of well-designed randomized<br />

trials as they appear in the literature. Until then it<br />

will remain a modality used passionately by those<br />

convicted of its perceived benefit to enhance<br />

healing.<br />

Selected References<br />

1. Stammers AH, Trowbridge C, Marko M,<br />

Woods EL, Brindisi N, Pezzuto J, Klayman<br />

M, Fleming S, Petzold J. Autologous<br />

Platelet Gel: Fad or Savoir? Do We Really<br />

Know? J Extra Corpor Technol. 2009;42:25-<br />

30.<br />

2. Rhee JS, Black M, Schubert U, Fischer S,<br />

et al. The functional role of blood platelet<br />

62<br />

<strong>com</strong>ponents in angiogenesis. Thromb<br />

Haemost. 2004;92:394-402.<br />

3. Everts PA, Knape JT, Weibrich G, et al.<br />

Platelet-rich plasma and platelet gel: a<br />

review. J Extra Corpor Technol.<br />

2006;38:174-87.<br />

4. Mehta S, Watson JT. Platelet rich<br />

concentrate: basic science and current<br />

clinical applications. J Orthop Trauma.<br />

2008;22:432-8.<br />

5. Singer AJ, Clark RA. Cutaneous wound<br />

healing. N Engl J Med. 1999;341:738-46.<br />

6. Charo IF, Ransohoff RM. The many roles of<br />

chemokines and chemokine receptors in<br />

inflammation. N Engl J Med. 2006;354:610-<br />

2.<br />

7. Soheil Y, Venters G, Vu S, et al. Role of<br />

growth factors in scar contraction: an in vitro<br />

analysis. Ann Plast Surg. 1995;34:495-501.<br />

8. Feiz-Erfan I, Harrigan M, Sonntag VK,<br />

Harrington TR. Effect of autologous platelet<br />

gel on early and late graft fusion in anterior<br />

cervical spine surgery. J Neurosurg Spine.<br />

2007;7:496-502.<br />

9. Tsai CH, Hsu HC, Chen YG, Lin MJ, Chen<br />

HT. Using the growth factors-enriched<br />

platelet glue in spinal fusion and its<br />

efficiency. J Spinal Disord Tech<br />

2009;22:246–250.<br />

10. Zavadil DP, Satterlee CC, Costigan JN, Holt<br />

DW, Shostrom VK. Autologous platelet gel<br />

and platelet-poor plasma reduce pain with<br />

total shoulder arthroplasty. J Extra Corpor<br />

Tech. 2007;39:177-182.<br />

11. Galasso O, Mariconda M, Romano G, et al.<br />

Expandable intramedullaryu nailing and<br />

platelet rich plasma to treat long bone non –<br />

unions. J Orthopaed Traumatol.<br />

2008;9:129-34.<br />

12. Trowbridge CC, Stammers, AH, Woods E,<br />

Yen B, Klayman M, Gilbert C. Use of<br />

platelet gel and its effects on infection in<br />

cardiac surgery. J ExtraCorp Tech.<br />

2005;37:381–6.


13. Englert SJ, Estep TH, Ellis-Stoll CC.<br />

Postoperative surgical chest and leg<br />

incision sites using platelet gel: a<br />

retrospective study. J ExtraCorp Tech.<br />

2008;40:225-8.<br />

14. Snyder EL, Calhoun BC. Topical platelet<br />

growth factor therapy: of lotions and<br />

potions. Transfusion. 2001;41:1186-9.<br />

15. Mazzucco L, Balbo V, Cattana E,<br />

Guaschino R, Borzini P. Not every PRP-gel<br />

is born equal. Evaluation of growth factor<br />

availability for tissues through four PRP-gel<br />

preparations: Fibrinet, RegenPRP-Kit,<br />

Plateltex and one manual procedure. Vox<br />

Sang. 2009;97:110-8.<br />

16. Giusti I, Rughetti A, D'Ascenzo S, Millimaggi<br />

D, Pavan A, Dell'Orso L, Dolo V.<br />

Identification of an optimal concentration of<br />

platelet gel for promoting angiogenesis in<br />

human endothelial cells. Transfusion.<br />

2009;49:771-8.<br />

17. Rademakers LM, Gründeman PF,<br />

Bolderman RW, van der Veen FH, Maessen<br />

JG. Stability of an autologous platelet clot in<br />

the pericardial sac: An experimental and<br />

clinical study. J Thorac Cardiovasc Surg.<br />

2009;137:1190-4.<br />

Affiliation:<br />

Director of <strong>Perfusion</strong> Services<br />

Geisinger Health System<br />

100 North Academy Ave<br />

M.C. 20-15<br />

Danville, PA 17822-2015<br />

(570) 214-2471 phone<br />

(570) 271-7062 fax<br />

ahstammers@geisinger.edu<br />

63


Robert Pascotto, MD, FACS<br />

Heart to Heart Mission: A Tribute to<br />

Volunteers<br />

This cardiac surgical program was initiated to<br />

fulfill a void and need for cardiac surgery at Jose<br />

Maria Cabral y Baez Hospital in Santiago,<br />

Dominican Republic. This is a 520 bed public<br />

hospital that cares for indigent patients and<br />

serves a population greater than 4.0 million<br />

people. There is no cardiac surgery in the area.<br />

The hospital has a medical school and residency<br />

program for postgraduate education affiliated<br />

with it.<br />

We did our first operative procedures September<br />

2002. Since then we have operated on 262<br />

patients with excellent results. The patients are<br />

mostly young individuals with valvular heart<br />

disease.<br />

I started the Cardiac Surgical <strong>Program</strong> in Fort<br />

Myers in 1975. Since then, our group has<br />

expanded to 7 Cardiac Surgeons and operate at<br />

3 centers, Southwest Regional Medical Center,<br />

Naples Community Hospital and Lee Memorial<br />

Health Park. These past 36 years have been<br />

very fulfilling, however I felt that at this point in<br />

my life helping to aid in the preservation of<br />

human life in a country less fortunate than our<br />

own was also an important calling. I have<br />

recently retired and have dedicated my time to<br />

further enhance the program.<br />

Our team of usually 14 – 16 members is<br />

<strong>com</strong>prised of nurses, technicians, and assistants,<br />

as well as doctors, who are not only using their<br />

personal vacation time to make these journeys,<br />

but are also paying their own way to do so. While<br />

there we have educated young doctors and<br />

hospital staff in the care and treatment of the<br />

cardiac surgical patient.<br />

64<br />

This program is strongly influenced by the<br />

tradition of service that physicians and the<br />

medical profession have. It provides a<br />

mechanism to expand one’s horizons and gain<br />

insight into the importance of a global vision and<br />

understanding in today’s world. It also provides<br />

another venue for continuing personal<br />

enrichment and self-education necessary for a<br />

well-rounded individual involved in the care of<br />

cardiac surgical patients. This emotionally rich<br />

and rewarding experience benefits not only the<br />

patients and their families, but has dramatically<br />

affected all team members personally.<br />

I hope to continue this ongoing program with<br />

donations from our hospitals, pharmaceutical<br />

<strong>com</strong>panies, manufacturers of medical products<br />

and their distributors, as well as individuals.<br />

Currently, the program is in need of assistance<br />

from those people and organizations that are in a<br />

position to help make this mission a continued<br />

success.


If any individuals would like to discuss and learn<br />

more or volunteer in this humanitarian endeavor,<br />

i.e. cardiac surgeons, physician assistants, scrub<br />

techs, OR or ICU nurses, anesthesiologists or<br />

CRNA's, please contact me at (239) 851-0142 or<br />

via email at rdpascotto@gmail.<strong>com</strong> .<br />

Biography:<br />

Dr. Robert D. Pascotto received his<br />

undergraduate training at Manhattan College and<br />

continued with his medical education at<br />

Creighton University After <strong>com</strong>pleting his general<br />

surgical residency at St. Vincent's Hospital and<br />

Medical Center in New York City, he continued<br />

with his Thoracic and Cardiovascular Surgery<br />

residency at Methodist Hospital, Baylor College<br />

of Medicine in Houston and Indiana University<br />

Medical Center. While at Baylor, Dr. Pascotto<br />

had the opportunity to train with one of the<br />

pioneers of Cardiovascular Surgery, Dr. Michael<br />

E. Debakey. Dr. Pascotto is board certified by the<br />

American Board of Surgery and the American<br />

Board of Thoracic Surgery. He is a Fellow of the<br />

American College of Cardiology, American<br />

College of Chest Physicians and American<br />

College of Surgeons. He is active on many<br />

hospital <strong>com</strong>mittees in a leadership position and<br />

past president of the Medical Staff.<br />

65

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