PowerPoint Presentation (PDF) - Perfusion.com
PowerPoint Presentation (PDF) - Perfusion.com
PowerPoint Presentation (PDF) - Perfusion.com
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Conflicting Evidence<br />
• Bleeding study<br />
• Hypothermia<br />
induces platelet<br />
inhibition.<br />
• Platelet function<br />
normal when<br />
restored to 37°C.<br />
• Fundamental Paper<br />
for normothermic<br />
practice today<br />
Valeri CR, Feingold H, Cassidy G, Ragno G, Khuri<br />
S, Altschule MD. Hypothermia-induced reversible<br />
platelet dysfunction. Ann Surg 1987;205:175-181.<br />
• Separated from CPB<br />
• as low as 34°C<br />
• no differences in<br />
blood loss<br />
• blood product use<br />
was similar between<br />
the groups<br />
Nathan HJ, Wells GA, Munson JL, Wozny D.<br />
Neuroprotective effect of mild hypothermia in<br />
patients undergoing coronary artery surgery with<br />
cardiopulmonary bypass: a randomized trial. 6<br />
Circulation 2001;104:I85-91.
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