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Small Animal Radiology and Ultrasound: A Diagnostic Atlas and Text

Small Animal Radiology and Ultrasound: A Diagnostic Atlas and Text

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552 <strong>Small</strong> <strong>Animal</strong> Radiolo g y <strong>and</strong> Ultrasono graphy<br />

Fig. 4-100 A 4-year-old male<br />

mixed breed dog had a right rear<br />

limb lameness for 5 months. Soft-tissue<br />

swelling is noted in the stifle<br />

joint (open arrows). There are areas<br />

of irregular bony proliferation on<br />

the proximal <strong>and</strong> distal margins of<br />

the patella <strong>and</strong> on the proximal<br />

aspect of the distal femoral articular<br />

surface (closed arrows). Diagnosis:<br />

Mild degenerative joint disease. This<br />

was secondary to rupture of the cranial<br />

cruciate ligament.<br />

Primary degenerative joint disease results from apparently normal wear <strong>and</strong> tear. No<br />

specific or predisposing cause can be identified. Secondary degenerative joint disease<br />

results from a specific or predisposing condition or event such as those listed below.<br />

●<br />

Trauma (injury to adjacent bone, ligament, tendon, articular cartilage, joint capsule)<br />

●<br />

Conformational or developmental abnormality (abnormal stress or use of the limb<br />

that results from congenital, inherited, or acquired limb deformities)<br />

●<br />

Metabolic, nutritional, <strong>and</strong> idiopathic disorders (e.g., hemophilia, mucopolysaccharidosis,<br />

hypervitaminosis A, hyperparathyroidism, or congenital hypothyroidism)<br />

●<br />

Neoplastic arthropathy (tumors arising from the periarticular soft tissues)<br />

●<br />

Infectious arthritis (bacterial, mycotic, viral, protozoal, <strong>and</strong> mycoplasmal arthritis)<br />

●<br />

Immune-mediated arthritis (erosive <strong>and</strong> nonerosive)<br />

●<br />

Crystal-induced arthritis (includes gout <strong>and</strong> pseudogout, or calcium pyrophosphate<br />

dihydrate [CPPD] deposition disease)<br />

●<br />

Villonodular synovitis<br />

D E G E N E R AT I V E J O I N T D I S E A S E<br />

Degenerative joint disease, also known as osteoarthritis <strong>and</strong> osteoarthrosis, is a common<br />

arthropathy with many diverse causes. The radiographic features of degenerative joint disease<br />

are similar regardless of the underlying etiology (Figs. 4-100 <strong>and</strong> 4-101). 425-429 Softtissue<br />

swelling usually is minimal. Periarticular periosteal proliferation occurs at the sites<br />

of joint capsule <strong>and</strong> ligamentous attachment <strong>and</strong> at the margins of the articular cartilage.<br />

This proliferation usually is smooth <strong>and</strong> uniformly mineralized with well-defined margins.<br />

The subchondral bone may become thinned, thickened, dense, or irregular. Intraarticular<br />

or periarticular bony densities may be seen. These densities may be due to avulsion fractures,<br />

joint capsule or tendinous mineralizations, or mineralization of detached articular<br />

cartilage fragments, known as joint mice or synovial osteochondromatosis. 431,436-467<br />

Narrowing of the joint space <strong>and</strong> subchondral bone cysts may be observed. Malalignment<br />

of articular surfaces or joint subluxation may be seen with some specific conditions; however,<br />

weight-bearing or stress radiographs may be required to demonstrate joint instability<br />

(Fig. 4-102). 11 In most cases, the radiographic findings are less extensive than those<br />

observed at surgery or necropsy. The more severe the radiographic findings, the poorer the<br />

prognosis despite the correction of any underlying disease. With severe degenerative<br />

changes, the underlying cause may be obscured. The progression of the radiographic<br />

changes usually is slow, with little difference observed over several months.<br />

Primary degenerative joint disease, resulting from normal wear <strong>and</strong> tear on a joint, is<br />

uncommon in small animals but may be observed as an incidental finding. It typically

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