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Antibody-Antigen Recognition and Antibody Development Antibody ...

Antibody-Antigen Recognition and Antibody Development Antibody ...

Antibodies - General •

Antibodies - General • Antibodies are proteins found in the blood and other bodily fluids of vertebrates. • Used by the immune system to neutralize bacteria, viruses, and other foreign particles. • Produced by B-Cells. • Identify specific markers on foreign bodies (antigens) called epitopes. Large antigens (like bacteria) may have many unique epitopes that antibodies can be developed against. © EnviroLogix 2006

Antibodies – General, Continued • Antibodies can be generated against proteins, nucleic acids, carbohydrates, lipids, small chemical groups, and peptides (10-15 amino acids long). • Small molecules such as chemicals or peptides may not be immunogenic (will not usually produce antibodies if they are injected into an animal). To make antibodies against small molecules they must be coupled to a large protein to form a hapten-carrier complex. • Antibodies are the key reagents in all immunoassays for many markets (health, environmental, veterinary, agriculture). © EnviroLogix 2006

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