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Fact#1: Limited Evidence Based<br />

Medicine Leading to Clinical Practice<br />

RCT of PCB for the Treatment of De Novo SFA Disease (ITT= PTA Only)<br />

PACIFIER<br />

(Medtronic)<br />

LEVANT I<br />

(Lutonix)<br />

Fem-PAC<br />

(Medrad)<br />

N=45<br />

-0.05<br />

N=35<br />

N=39<br />

N=34<br />

N=31<br />

Thunder<br />

N=48<br />

(Medrad)<br />

N=41<br />

0.3<br />

0.46<br />

0.4<br />

0.61<br />

0.8<br />

1.09<br />

POBA<br />

PCB<br />

1.7<br />

-0.5 0 0.5 1 1.5 2<br />

Angiographic Late Loss (mm)<br />

“Still less than<br />

several<br />

hundred<br />

patients having<br />

6 month<br />

angiographic<br />

data and long<br />

term follow up”

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