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Vascular Malformations Smith 12-12-2012 - Inova Health System

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2/8/20<strong>12</strong><br />

Hereditary Hemorrhagic<br />

Telangiectasia<br />

>3 concurrent cerebral AVMS –Rare!<br />

An angiodyplastic disorder with AD inheritance<br />

AVM<br />

• Dysregulated<br />

angiogenesis <br />

continued vascular<br />

remodeling<br />

• Peak age: 20-40 year<br />

old<br />

• Risk of hemorrhage: 2-<br />

4%/year<br />

– ~50% present with<br />

symptoms of<br />

hemorrhage<br />

NECT<br />

AVM Grading: Spetzler -Martin<br />

Scale<br />

• Size<br />

– Small (6 cm) = 3<br />

• Location<br />

– Noneloquent = 0<br />

– Eloquent = 1<br />

• Venous drainage<br />

– Superficial = 0<br />

– Deep = 1<br />

3

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