Biomedical Engineering - Technische Universiteit Eindhoven

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Biomedical Engineering - Technische Universiteit Eindhoven

Partners in Health

Biomedical Engineers need a broad range of knowledge, skills and facilities. The excellent

facilities at TU/e are supplemented with the facilities and clinical experience accessed

through our collaborations with other universities, academic hospitals and industrial

corporations. In addition, the three leading universities of technology in the Netherlands

have joined forces in the 3TU Federation, so they can share knowledge and strengthen

their positions nationally and internationally.

Heart for science

A shining example of engineers improving healthcare

Department of Biomedical Engineering

Engineers in a Clinical Environment

We work closely with hospitals to optimize the mutual benefits

of engineers in a clinical environment, including a longestablished

cooperation with the university and academic

hospital of Maastricht (MUMC+), where parts of the Medical

Engineering master program take place. We also collaborate

with the University Medical Center (UMC) in Utrecht, the

Academic Medical Center (AMC) in Amsterdam and the

Catharina Hospital in Eindhoven. Several part-time professors

in our department are doctors and one of our part-time

professors is a clinical chemist who works in three hospitals in

Eindhoven and Veldhoven.

Biomedical Engineers are good mediators

between the biomedical and clinical researchers

and the more specialized engineers.” Frans Smeets,

Managing Director, Maastricht Instruments

Valorization

As valorization is one of the spearheads of our policy, we enjoy

various forms of cooperation with trade and industry. Amongst

our industrial partners are Philips Healthcare, DSM, Medtronic

Bakken Research and Maastro. In fact, our cooperation

with industry is close and very successful. Evidence of

this is provided by TU/e’s placement in the 2009 Leiden

Ranking, published by the Center for Science and Technology

Studies (CWTS), as the global leader in the field of industry

cooperation.

The fact that several spin-off companies have emerged from

the department of Biomedical Engineering shows that our

research has societal and economic impact. For example, the

spin-off HemoLab operates independently to test products

and protocols in the field of cardiovascular technology, taking

them to a higher level of application for pathophysiological

processes. The spin-off QTIS/e focuses on developing and

commercializing tissue-engineered heart valves and blood

vessels. We encourage innovative entrepreneurship by offering

our students and researchers special education (through

the Brabant Center of Entrepreneurship & TiasNimbas) and

facilities (TU/e innovation Lab).

Heart for science

Consider a baby, suffering from a dysfunctional aortic

heart valve. You could treat this by implanting a traditional

mechanical heart valve, but it would require multiple

operations throughout her lifetime, because the mechanical

heart valve cannot adapt to her growing body. Her quality

of life could be greatly improved if it were possible to

implant an autogenic heart valve. Autogenic heart valves

are created from a person’s own cells and will adapt and

grow along with their body. Fabrication of an autogenic

heart valve is one of the research topics in the Department

of Biomedical Engineering at TU/e.

Protagoras

Protagoras: study association Biomedical Engineering

If you want to get in touch with our Biomedical Engineering

students for information, promotion, lectures or excursions,

Protagoras is your point of contact. Protagoras is the study

association for all Biomedical Engineering students,

in charge of:

• Education: Study materials such as books and old exams

are made available and we give feedback and evaluation

for the department.

• Experience: We organize excursions, lectures, symposia

and study tours abroad.

• Entertainment: We organize various parties and other

activities, such as bowling and weekly drinks in our own bar.

Contact Information

Technische Universiteit Eindhoven (TU/e)

Department of Biomedical Engineering

Tel: +31 (0)40 247 5132

E-mail: secretariaat.bmt@tue.nl

More information, contact details,

route & map on website: www.tue.nl/bmt

Protagoras

Biomedical Engineering study association

Tel: +31 (0)40 247 2758

E-mail: extern@protagoras.tue.nl

More information, contact details,

route & map on website: www.protagoras.tue.nl

Biomedical

Engineering

Where Engineers

Improve Healthcare

Where innovation starts


Profile

Education

Research

There is an endless demand in modern healthcare for technologies to improve the diagnosis,

treatment and prevention of health problems. To meet this demand, the Eindhoven University

of Technology (TU/e) focuses a great deal of its research and education on health technologies

and has a department devoted entirely to this socially vital area: Biomedical Engineering.

Biomedical engineers improve human health through cross-disciplinary activities that integrate

the engineering sciences with the biomedical sciences and clinical practice.

Biomedical Engineering (BME) is a familiar discipline around the world, but there are many

different types of programs. In 1997 TU/e was one of the first universities to introduce an integrated

five-year BME program leading to a master’s degree. From the outset, the curriculum integrates

the natural sciences and engineering disciplines with cell biology and pathophysiology.

It is also designed to meld seamlessly with the research in our own department.

Research ranges from regenerative medicine to image anaylsis to molecular

engineering. The research is performed in eight specialized research groups that

cooperate in several mutual projects, such as developing an artificial human

kidney and designing personalized medicines.

Synergy of education and research

The Department of Biomedical Engineering provides

high-quality academic education and cutting-edge research.

• Education

One bachelor’s track, Biomedical Engineering, and two

master’s tracks, Biomedical Engineering and Medical

Engineering.

• Research

performed in eight specialized research groups and covers

everything from regenerative medicine to image analysis

to molecular engineering.

Contact between the 300 undergraduate students, 200

graduate students and 180 researchers is open and personal.

This allows the students to have good interaction with the

scientists and medical specialists. As a result, our students

are capable of performing and coordinating basic and applied

scientific research in the field of biomedical engineering from

a very early stage in their careers. The close collaboration

between our researchers also fosters cooperation between

research groups in numerous shared projects, such as the

development of an artificial human kidney and the design of

personalized medicines.

“To discover why these diseases develop is a

key driver for me.” Prof.dr.ir. Luc Brunsveld, Chemical Biology /

Department of Biomedical Engineering

Partners in health

The Department of Biomedical Engineering collaborates

closely with other health-oriented departments at TU/e, other

universities, academic hospitals and industrial partners. Much

of this collaboration occurs through international contacts in

countries such as China, the U.S.A., Australia and European

countries.

Bachelor’s program

The three-year bachelor’s program focuses on research and

development and offers a broad range of knowledge and skills.

Students take courses on mathematics, physics, chemistry,

electrical engineering, mechanical engineering, computer

science, physiology and biology. From day one, they work

together in teams on state-of-the-art biomedical problems,

so that they also develop such valuable skills as cooperation,

communication and reporting. The students are guided by

graduate students, post-docs and academic staff, including

professors, in these projects.

Besides the fixed parts of the bachelor’s program, students

choose their own track. Many students choose to broaden

their scope by studying another field of research, perhaps

at another university or even abroad. Popular tracks are

Medicine and Management Sciences.

Master programs

When it comes time to move on to a master’s degree program,

there are plenty of appropriate ones to choose from at other

universities. Students who have taken specific medical

elective courses are eligible to the admission procedure of

the Selective Utrecht Medical Master (SUMMA) program at

Utrecht University, the Arts-Klinisch Onderzoeker program

(AKO) of the University at Maastricht, and the Medical Masters

programs in Groningen (ZIG) and Amsterdam. However, most

students decide to follow a master program that belongs to

the Life Sciences and Engineering graduate program. This TU/e

graduate program includes the master program Biomedical

Engineering and the master program Medical Engineering.

Biomedical Engineering

The Master in Biomedical

Engineering is strongly

research focused and aims to

develop general solutions for

a patient group. Biomedical

engineers specialize in one

particular field relevant to

clinical problems.

Medical Engineering

The Master in Medical

Engineering aims to

integrate advanced medical

technologies into clinical

practice. Medical engineers

develop solutions to clinical

problems. They solve patient

specific problems, through

models and technologies.

At the start of both master programs, students become a

member of one of our eight research groups. They design their

own personal curriculum in cooperation with a professor. Most

students go abroad for a three-to-four-month internship as part

of the program, with popular destinations being the U.S.A. and

Australia. In fact, the study materials for both the bachelor’s

and master programs are in English, so all students are wellprepared

for an international career.

Careers for a biomedical engineer

Most graduates will start working as a researcher after

finishing their master Biomedical Engineering or Medical

Engineering. But some of them become: developer, project

manager, lecturer, salesman, advisor...

The sectors and companies that graduates (after their master)

work in can be found in the diagram below.

• Universities (PhD students) (30%)

• (Academic) Hospitals (22%)

• Development of medical

products (16%)

• Pharmaceutical companies (10%)

• Small companies (10%)

• National research institutes (5%)

• Organisation and finances (5%)

• Other (2%)

As there is always more to learn, graduates may continue

studying. They often choose for an education program at

the School for medical Physics and Engineering to become a

clinical physicist, a qualified medical engineer or qualified

medical Informatics professional. Or they choose a four year

research program to become a PhD.

“In my biomedical engineering study, I learned

to discuss with all kind of engineers at a high

level and to quickly identify the innovative

aspects of inventions. This boosted my career

as a consultant and enables me to efficiently

translate technical ideas into commercial

products.” Jasper Levink, Business development

consultant, ttopstart

Soft Tissue Biomechanics and

Engineering

Prof.dr.ir. Frank Baaijens &

Prof. dr. Carlijn Bouten

Through experimentation and numerical

modeling, we study how living tissues

adapt to mechanical loading. We apply

the knowledge of tissue proliferation

and differentiation thus obtained to

biomedical problems such as prosthesis

design, pressure ulcers and the

engineering of living tissues and organs

(e.g., heart valves and intervertebral

discs).

Cardiovascular Biomechanics

Prof.dr.ir. Frans van de Vosse

We develop experimental and

computational models of the cardiovascular

system for the purpose of

supporting medical decision making

in clinical practice. The models can be

used in the development of methods

for quantitative measurements (e.g.,

pressure, flow, and tissue deformation)

and to predict the outcome of medical

intervention (e.g., surgery and

medication).

Orthopaedic Biomechanics

Prof.dr. Keita Ito

We combine engineering and biology

to expand our understanding of the

biomechanical function of musculoskeletal

tissues, as well as their adaptive

developmental and physiological nature.

Our investigations of degenerative

diseases and regenerative treatment

strategies target the three tissues bone,

articular cartilage and intervertebral disc.

Biomedical Image Analysis

Prof.dr.ir. Bart ter Haar Romenij

We develop new robust image analysis

algorithms for computer-aided diagnosis

and interactive 3D visualization to help

in extracting quantitative information

from medical images. We apply these

techniques to practical clinical problems,

with an emphasis on the cardiovascular

system (3D deformation, ablation,

4D flow, interventions) and the brain

(tractography, surgery navigation).

Biomodeling & Bioinformatics

Prof.dr. Peter Hilbers

We investigate and apply molecular

modeling methods, machine learning,

systems biology and parameter

estimation techniques to construct

computational models. With these

models, we improve our qualitative and

quantitative knowledge of biomedical

processes and structures, such as

biomembranes, protein interactions

and complex biochemical networks, and

diseases, such as metabolic syndrome

and diabetes mellitus.

Chemical Biology

Prof.dr.ir. Luc Brunsveld

We apply novel chemistry techniques to

biology to enhance our understanding

of diseases on the molecular level and

develop new or personalized drugs.

Our targets of interest are studies of

the nuclear receptors that play a role

in cancer and the visualization and

assembly processes of proteins, such as

disease relevant membrane proteins.

Biomedical Chemistry

Prof.dr. Bert Meijer

Our aim is to develop new molecular

tools and biomaterials for biomedical

research using supramolecular

interactions. We create new materials

for tissue engineering (e.g., an artificial

kidney), novel peptide-based scaffolds

for drug delivery, and proteins with

attractive biomedical properties for

molecular imaging. We focus on artificial

structures that are indistinguishable

from their natural counterparts.

Biomedical NMR

Prof.dr. Klaas Nicolay

We develop non-invasive imaging

techniques to improve the diagnosis and

treatment of cardiovascular diseases,

metabolic disorders and cancer. Our

research focuses on expanding the

capabilities of Magnetic Resonance

Imaging (MRI) and Spectroscopy (MRS).

Following initial validation in preclinical

studies, we aim to translate promising

methods into clinical use.

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