the pursuit of parkinson's - The University of Alabama at Birmingham
the pursuit of parkinson's - The University of Alabama at Birmingham
the pursuit of parkinson's - The University of Alabama at Birmingham
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News Briefs<br />
rel<strong>at</strong>ed educ<strong>at</strong>ional programs.<br />
“<strong>The</strong> Cancer Resource Library will be an<br />
invaluable tool for p<strong>at</strong>ients who want to become<br />
proactive in <strong>the</strong>ir tre<strong>at</strong>ment and recovery,” says<br />
Edward Partridge, M.D., associ<strong>at</strong>e director for<br />
cancer control and popul<strong>at</strong>ion science <strong>at</strong> <strong>the</strong> cancer<br />
center. “A visit may be helpful to <strong>the</strong> newly<br />
diagnosed p<strong>at</strong>ient, or for those seeking follow-up<br />
inform<strong>at</strong>ion during or after tre<strong>at</strong>ment.”<br />
HUW THOMAS NAMED<br />
DEAN OF DENTISTRY<br />
Huw Francis Thomas, B.D.S., M.S., Ph.D.,<br />
has been named dean <strong>of</strong> <strong>the</strong> School <strong>of</strong> Dentistry,<br />
by acting provost Eli Capilouto. Thomas previously<br />
was <strong>the</strong> chairman <strong>of</strong> <strong>the</strong> Department <strong>of</strong><br />
Pedi<strong>at</strong>ric Dentistry <strong>at</strong> <strong>the</strong> <strong>University</strong> <strong>of</strong> Texas<br />
Health Science Center, San Antonio.<br />
“Dr. Thomas has a strong commitment to p<strong>at</strong>ient<br />
care, quality teaching, and community outreach programs,”<br />
Capilouto says. “He also understands and<br />
embraces <strong>the</strong> very important role a strong research<br />
program plays in <strong>the</strong> enhancement and growth <strong>of</strong> <strong>the</strong><br />
school. He is n<strong>at</strong>ionally recognized for his leadership<br />
in all <strong>of</strong> <strong>the</strong>se areas, as well as his ability to develop<br />
collabor<strong>at</strong>ive rel<strong>at</strong>ionships to bring dental educ<strong>at</strong>ion<br />
and better oral health to all facets <strong>of</strong> <strong>the</strong> popul<strong>at</strong>ion.”<br />
Thomas earned his bachelor <strong>of</strong> dental surgery<br />
degree from Guy’s Hospital <strong>at</strong> <strong>the</strong> <strong>University</strong> <strong>of</strong><br />
London, England. He earned a master’s degree in<br />
dental research from <strong>the</strong> <strong>University</strong> <strong>of</strong> Rochester, a<br />
certific<strong>at</strong>e in pedi<strong>at</strong>ric dentistry from <strong>the</strong> Eastman<br />
Dental Center, and a doctor<strong>at</strong>e in biomedical sciences<br />
from <strong>the</strong> <strong>University</strong> <strong>of</strong> Connecticut.<br />
“<strong>The</strong> School <strong>of</strong> Dentistry <strong>at</strong> UAB has an excellent<br />
reput<strong>at</strong>ion and is well situ<strong>at</strong>ed to continue<br />
providing high-quality educ<strong>at</strong>ion while serving its<br />
p<strong>at</strong>ients and enhancing its research efforts,”<br />
Thomas says. “I very much look forward to being<br />
part <strong>of</strong> this bright future.”<br />
FACULTY NEWS<br />
NATIONAL NEUROFIBROMATOSIS<br />
FOUNDATION NAMES BRUCE R. KORF<br />
NEW CHAIRMAN OF MEDICAL<br />
AFFAIRS COMMITTEE<br />
Bruce R. Korf, M.D., Ph.D., chair <strong>of</strong> <strong>the</strong> recently<br />
cre<strong>at</strong>ed Department <strong>of</strong> Genetics and <strong>the</strong> Wayne<br />
H. Finley and Sara Crews Finley Chair <strong>of</strong> Medical<br />
Genetics, has been named as <strong>the</strong> new chairman <strong>of</strong><br />
<strong>the</strong> Medical Affairs Committee for <strong>the</strong> N<strong>at</strong>ional<br />
Neur<strong>of</strong>ibrom<strong>at</strong>osis Found<strong>at</strong>ion (NNFF).<br />
Korf is one <strong>of</strong> <strong>the</strong> leading clinical experts and<br />
clinical researchers in <strong>the</strong> field <strong>of</strong> neur<strong>of</strong>ibrom<strong>at</strong>osis<br />
and has worked with <strong>the</strong> NNFF for more than<br />
15 years. He previously has served as chairman <strong>of</strong><br />
<strong>the</strong> found<strong>at</strong>ion’s Clinical Care Advisory Board<br />
and as chairman <strong>of</strong> <strong>the</strong> Found<strong>at</strong>ion’s Medical<br />
Policy Committee.<br />
“Dr. Korf’s distinguished career as both scientist<br />
and physician, combined with his long record<br />
<strong>of</strong> service to NF, make him <strong>the</strong> ideal choice to lead<br />
<strong>the</strong> found<strong>at</strong>ion’s medical and research programs,”<br />
says found<strong>at</strong>ion president Peter Bellermann. “<strong>The</strong><br />
found<strong>at</strong>ion has built its reput<strong>at</strong>ion by facilit<strong>at</strong>ing<br />
collabor<strong>at</strong>ion among scientists and institutions<br />
th<strong>at</strong> are normally in competition for resources and<br />
ideas; Dr. Korf’s outstanding credentials will lend<br />
gre<strong>at</strong> weight to <strong>the</strong> found<strong>at</strong>ion’s efforts to continue<br />
this tradition.”<br />
“As we learn more about <strong>the</strong> biology <strong>of</strong> <strong>the</strong><br />
neur<strong>of</strong>ibrom<strong>at</strong>oses, I look forward to working<br />
closely with <strong>the</strong> N<strong>at</strong>ional Neur<strong>of</strong>ibrom<strong>at</strong>osis<br />
Found<strong>at</strong>ion in its efforts to facilit<strong>at</strong>e <strong>the</strong> transl<strong>at</strong>ion<br />
<strong>of</strong> this new knowledge to better methods <strong>of</strong><br />
diagnosis and tre<strong>at</strong>ment,” Korf says.<br />
NF is a genetic disorder th<strong>at</strong> causes tumors to<br />
grow along nerves throughout <strong>the</strong> body. NF<br />
affects 100,000 Americans: 1 in 4,000 have NF<br />
Type 1, 1 in 40,000 have NF Type 2. <strong>The</strong> NNFF,<br />
a nonpr<strong>of</strong>it organiz<strong>at</strong>ion, is <strong>the</strong> leading resource<br />
on NF. NNFF provides direct services to children<br />
and adults with NF, as well as inform<strong>at</strong>ion and<br />
resources to <strong>the</strong> public and medical pr<strong>of</strong>essionals<br />
via a toll-free number, 1-800-323-7938, and <strong>the</strong><br />
NF Web site, [www.nf.org].<br />
ALVAREZ NAMED GYN ONC<br />
DIVISION DIRECTOR<br />
Ronald D. Alvarez, M.D., succeeded Edward<br />
E. Partridge, M.D., as director <strong>of</strong> <strong>the</strong> Division <strong>of</strong><br />
Gynecologic Oncology in <strong>the</strong> Department <strong>of</strong><br />
Obstetrics and Gynecology on October 1, 2003.<br />
After 13 years as division director, Partridge<br />
stepped down to devote more time to community-based<br />
research and service, particularly ongoing<br />
programs for <strong>the</strong> underserved in cancer care,<br />
prevention, and control. He will continue to see<br />
p<strong>at</strong>ients and serve as vice chairman <strong>of</strong> <strong>the</strong><br />
Department <strong>of</strong> Obstetrics and Gynecology and as<br />
associ<strong>at</strong>e director for cancer prevention and control<br />
in <strong>the</strong> UAB Comprehensive Cancer Center.<br />
Alvarez also holds appointments as pr<strong>of</strong>essor <strong>of</strong><br />
gynecologic oncology and senior scientist in <strong>the</strong><br />
Cancer Center, where he leads <strong>the</strong> Women’s<br />
Cancer Program. He is also a senior scientist in<br />
<strong>the</strong> UAB Gene <strong>The</strong>rapy Center and collabor<strong>at</strong>es<br />
on developing gene <strong>the</strong>rapy str<strong>at</strong>egies for reproductive<br />
malignancies.<br />
A n<strong>at</strong>ive <strong>of</strong> New Orleans and gradu<strong>at</strong>e <strong>of</strong> LSU,<br />
Alvarez received his M.D. degree from LSU<br />
Medical Center in 1983. He completed his<br />
internship (1984) and residency (1986) <strong>at</strong> UAB.<br />
He was chief resident in OB/GYN before joining<br />
<strong>the</strong> UAB faculty as an instructor and research fellow<br />
in 1987. <strong>The</strong> recipient <strong>of</strong> numerous awards<br />
and honors, he has been included several times in<br />
<strong>The</strong> Best Doctors in America and on Good<br />
Housekeeping’s list <strong>of</strong> best doctors for women. He<br />
also received <strong>the</strong> 1994 American College <strong>of</strong><br />
OB/GYN Outstanding Pr<strong>of</strong>essor Award.<br />
On future plans for <strong>the</strong> Division <strong>of</strong> Gynecologic<br />
Oncology, Alvarez comments, “We expect to build<br />
upon <strong>the</strong> excellent found<strong>at</strong>ion established under<br />
Dr. Partridge’s superb leadership. We plan to do<br />
this by enhancing our clinical services and continuing<br />
our efforts to educ<strong>at</strong>e <strong>the</strong> practitioners <strong>of</strong><br />
today and tomorrow. Ano<strong>the</strong>r major goal is to continue<br />
<strong>the</strong> cutting-edge research th<strong>at</strong> will improve<br />
<strong>the</strong> lives <strong>of</strong> women <strong>at</strong> risk for or diagnosed with a<br />
gynecologic cancer.”<br />
WEISS RECEIVES PRESTIGIOUS<br />
JAVITS AWARD FOR BRAIN RESEARCH<br />
David Weiss, Ph.D., pr<strong>of</strong>essor <strong>of</strong> neurobiology,<br />
has been selected to receive a Sen<strong>at</strong>or Jacob Javits<br />
Award in <strong>the</strong> Neurosciences by <strong>the</strong> N<strong>at</strong>ional<br />
Institute <strong>of</strong> Neurological Disorders and Stroke<br />
(NINDS), one <strong>of</strong> <strong>the</strong> N<strong>at</strong>ional Institutes <strong>of</strong> Health<br />
(NIH). <strong>The</strong> award is for $2.4 million over seven<br />
years to carry out fundamental studies on <strong>the</strong><br />
dynamics <strong>of</strong> <strong>the</strong> GABA receptor, <strong>the</strong> brain’s major<br />
molecular detector for restraining or inhibiting electrical<br />
activity. <strong>The</strong> receptor plays a role in such<br />
actions as preventing epileptic seizures. Anxiety<br />
and rage can occur due to ineffective function <strong>of</strong> <strong>the</strong><br />
GABA inhibition system, and <strong>the</strong> effects <strong>of</strong> alcohol<br />
and actions <strong>of</strong> sed<strong>at</strong>ives target <strong>the</strong> GABA system.<br />
<strong>The</strong> prestigious Javits Investig<strong>at</strong>or Awards were<br />
established by <strong>the</strong> U.S. Congress in 1983 to honor<br />
<strong>the</strong> l<strong>at</strong>e Sen<strong>at</strong>or Jacob Javits, who suffered from<br />
amyotrophic l<strong>at</strong>eral sclerosis (ALS), a degener<strong>at</strong>ive<br />
neurological disorder also known as Lou Gehrig’s<br />
disease. Javits was a champion <strong>of</strong> research into a<br />
wide variety <strong>of</strong> disorders <strong>of</strong> <strong>the</strong> brain. <strong>The</strong> awards<br />
are intended to recognize and support <strong>the</strong> research<br />
<strong>of</strong> distinguished investig<strong>at</strong>ors who are expected to<br />
be highly productive over <strong>the</strong> next seven years.<br />
Weiss pioneered <strong>the</strong> use <strong>of</strong> labor<strong>at</strong>ory techniques<br />
to allow for molecular manipul<strong>at</strong>ion <strong>of</strong> <strong>the</strong><br />
brain’s GABA receptors, as well as visualiz<strong>at</strong>ion <strong>of</strong><br />
<strong>the</strong> dynamics <strong>of</strong> GABA receptors interacting with<br />
chemical signals from neighboring nerve cells in<br />
<strong>the</strong> brain. This work forms <strong>the</strong> basis for extending<br />
<strong>the</strong> understanding <strong>of</strong> a number <strong>of</strong> aspects <strong>of</strong> brain<br />
function where <strong>the</strong> process <strong>of</strong> chemical inhibition<br />
in <strong>the</strong> brain is essential.<br />
“Weiss’s research into GABA’s interactions<br />
within <strong>the</strong> brain has led to <strong>the</strong> development <strong>of</strong><br />
new ways <strong>of</strong> tracking those processes in <strong>the</strong> living<br />
system in order to provide a precise view <strong>of</strong> <strong>the</strong><br />
GABA receptor in action,” says Michael<br />
Friedlander, Ph.D., chair <strong>of</strong> <strong>the</strong> Department <strong>of</strong><br />
Neurobiology. “It is for <strong>the</strong>se breakthroughs and<br />
<strong>the</strong> promise <strong>of</strong> important discoveries to come<br />
from his program th<strong>at</strong> <strong>the</strong> NIH has made this<br />
prestigious award to Dr. Weiss.”<br />
Weiss received his Ph.D. in neuroscience from<br />
Baylor College <strong>of</strong> Medicine in 1987 and carried out<br />
a postdoctoral fellowship in physiology and biophysics<br />
<strong>at</strong> <strong>the</strong> <strong>University</strong> <strong>of</strong> Miami School <strong>of</strong><br />
Medicine. He served on <strong>the</strong> faculty <strong>of</strong> <strong>the</strong> <strong>University</strong><br />
<strong>of</strong> South Florida before joining UAB in 1995.<br />
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