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<strong>of</strong> autoimmunity centers to speed transl<strong>at</strong>ion <strong>of</strong><br />

basic research into new therapies and to further<br />

our understanding <strong>of</strong> human immunology.”<br />

UAB’s long and notable history <strong>of</strong> basic and<br />

clinical study in the field <strong>of</strong> autoimmune research<br />

was a key factor in the NIH’s decision to name it<br />

a center <strong>of</strong> excellence. “UAB received the highest<br />

score among all institutions applying for this<br />

award,” Carter says. “We have gre<strong>at</strong> expertise and<br />

many proven strengths in this area <strong>of</strong> research.”<br />

In addition to its basic research activities, the<br />

center, as part <strong>of</strong> its grant applic<strong>at</strong>ion, has proposed<br />

two clinical studies: one on psori<strong>at</strong>ic arthritis<br />

and one on lupus. “A steering committee <strong>of</strong><br />

leaders representing all the centers will decide<br />

which clinical studies to conduct and which centers<br />

will particip<strong>at</strong>e based on each center’s expertise,”<br />

Carter says. “If one or both <strong>of</strong> UAB’s proposed<br />

clinical studies are selected, the center will<br />

receive additional funding to support these trials.”<br />

“Collabor<strong>at</strong>ive center projects will unite the<br />

expertise <strong>of</strong> investig<strong>at</strong>ors working in diverse areas<br />

<strong>of</strong> human autoimmune disease,” says Larry W.<br />

Moreland, M.D., director <strong>of</strong> clinical activities for<br />

the UAB center. “Taking part in the development<br />

and implement<strong>at</strong>ion <strong>of</strong> these groundbreaking<br />

investig<strong>at</strong>ions will expand our collective knowledge<br />

and place UAB <strong>at</strong> the forefront <strong>of</strong> human<br />

immunological research.”<br />

NIH AWARDS UAB<br />

NEW CENTER ON MINORITY<br />

HEALTH DISPARITIES<br />

Diabetes kills African Americans <strong>at</strong> a r<strong>at</strong>e double<br />

th<strong>at</strong> <strong>of</strong> whites. Colon-cancer mortality is a<br />

third higher, and overall mortality is 50 percent<br />

higher. Now UAB will use a $4.25 million federal<br />

grant to try to help change those st<strong>at</strong>istics through<br />

research, screening and educ<strong>at</strong>ion programs, and<br />

training <strong>of</strong> health-rel<strong>at</strong>ed pr<strong>of</strong>essionals.<br />

The four-year grant comes from the NIH’s<br />

N<strong>at</strong>ional Center on Minority Health and Health<br />

Disparities. It establishes a Regional Deep South<br />

Project Export Center <strong>of</strong> Excellence for Minority<br />

Health (Project Export) to begin developing a<br />

health-disparities center. Selwyn M. Vickers,<br />

M.D., pr<strong>of</strong>essor <strong>of</strong> surgery, is principal investig<strong>at</strong>or<br />

for the program. The grant was developed in<br />

conjunction with co-principal investig<strong>at</strong>ors Mona<br />

Fouad, M.D., Edward Partridge, M.D., and<br />

C<strong>at</strong>arina Kiefe, M.D.<br />

“The health gap between minorities and whites<br />

is a problem th<strong>at</strong> st<strong>at</strong>istics make obvious, and it is<br />

particularly severe in the Black Belt counties <strong>of</strong><br />

<strong>Alabama</strong> with highest concentr<strong>at</strong>ions <strong>of</strong> African<br />

Americans,” Vickers says. “This new center <strong>of</strong><br />

excellence, incorpor<strong>at</strong>ing Project Export, will help<br />

coordin<strong>at</strong>e and build on existing efforts <strong>at</strong> UAB<br />

to comb<strong>at</strong> this problem <strong>of</strong> health disparities in<br />

our st<strong>at</strong>e and region.”<br />

UAB’s center is one <strong>of</strong> seven around the n<strong>at</strong>ion<br />

to receive st<strong>at</strong>us as a comprehensive center <strong>of</strong><br />

excellence and full funding in this fiscal year. The<br />

center aims to build partnerships <strong>at</strong> institutions<br />

enrolling a significant number <strong>of</strong> students from<br />

health-disparity popul<strong>at</strong>ions and will promote<br />

particip<strong>at</strong>ion and training in biomedical and<br />

behavioral research <strong>at</strong> these historically black colleges<br />

and universities.<br />

Vickers noted th<strong>at</strong> Project Export initially will<br />

reach out to the community through screening<br />

and educ<strong>at</strong>ion programs for diabetes and colon<br />

cancer. The diabetes program will be conducted<br />

in Jefferson County in associ<strong>at</strong>ion with the faithbased<br />

Center for Urban Missions, and colon cancer<br />

will be the target <strong>of</strong> programs in Macon<br />

County in partnership with the BND Cancer<br />

Center, a priv<strong>at</strong>e organiz<strong>at</strong>ion.<br />

Project Export will be an integral part <strong>of</strong> the center<br />

and make use <strong>of</strong> UAB’s research and training<br />

expertise in partnership with historically black colleges<br />

and universities in the st<strong>at</strong>e. “There is a need<br />

to recruit and train minorities as health workers,<br />

particularly in the Black Belt,” Vickers says. “A<br />

summer training program is planned in conjunction<br />

with the black colleges in order to prepare students<br />

for careers in allied-health pr<strong>of</strong>essions.”<br />

USING WIRELESS TECHNOLOGY TO<br />

IMPROVE EMERGENCY MEDICAL CARE<br />

Rapid advances in wireless communic<strong>at</strong>ion<br />

technology could provide big benefits in improving<br />

emergency medical response, say UAB<br />

researchers. The l<strong>at</strong>est technology could produce<br />

major improvements in the 911 system and in<br />

how Emergency Medical Services (EMS) teams<br />

handle medical emergencies ranging from heart<br />

<strong>at</strong>tacks to large-scale disasters.<br />

UAB researchers have received a $3.2 million<br />

contract from the N<strong>at</strong>ional Library <strong>of</strong> Medicine, a<br />

branch <strong>of</strong> the NIH, to study the integr<strong>at</strong>ion <strong>of</strong><br />

wireless technology with EMS services. The study,<br />

called Advanced Network Infrastructure for Health<br />

and Disaster Management, is directed by Helmuth<br />

Orthner, Ph.D., pr<strong>of</strong>essor <strong>of</strong> health inform<strong>at</strong>ics in<br />

UAB’s School <strong>of</strong> Health Rel<strong>at</strong>ed Pr<strong>of</strong>essions.<br />

“Our ability to handle medical emergencies is<br />

<strong>at</strong> a revolutionary threshold with the emergence<br />

<strong>of</strong> technologies such as secure, high-speed wireless<br />

communic<strong>at</strong>ions and powerful hand-held computing<br />

and communic<strong>at</strong>ion devices,” says<br />

Orthner. “This study will allow us to test how to<br />

integr<strong>at</strong>e these technologies within the EMS community<br />

in an important new way.”<br />

Orthner says the lessons learned will have value<br />

for EMS teams responding to any kind <strong>of</strong> medical<br />

emergency. He says any changes to the current<br />

system must be capable <strong>of</strong> rapid, failsafe escal<strong>at</strong>ion<br />

so th<strong>at</strong> the system can seamlessly respond to<br />

situ<strong>at</strong>ions ranging from an individual 911 call to<br />

major disasters such as c<strong>at</strong>astrophic we<strong>at</strong>her<br />

events or terrorist <strong>at</strong>tacks.<br />

Co-principal investig<strong>at</strong>ors with Orthner are<br />

Gary Grimes, Ph.D., UAB pr<strong>of</strong>essor <strong>of</strong> engineering,<br />

and Thomas Terndrup, M.D., chair <strong>of</strong> the<br />

Department <strong>of</strong> Emergency Medicine.<br />

SCREEN-SAVER PROVES EFFECTIVE IN<br />

EDUCATING HOSPITAL PHYSICIANS<br />

A training program th<strong>at</strong> uses interactive screensaver<br />

images linked to a Web site to prepare hospital-based<br />

clinicians to respond to bioterrorist<br />

<strong>at</strong>tacks is an effective altern<strong>at</strong>ive to more costly<br />

and more time-consuming educ<strong>at</strong>ional methods,<br />

according to a recent study published in the<br />

American Journal <strong>of</strong> Infection Control. Thomas<br />

Terndrup, M.D., chair <strong>of</strong> the Department <strong>of</strong><br />

Emergency Medicine and director <strong>of</strong> the Center<br />

for Emergency Care and Disaster Preparedness,<br />

led the pilot study to develop and test the new<br />

training program, available on the center’s Web<br />

site <strong>at</strong> [www.uab.edu/cecdp].<br />

“Before the terrorist <strong>at</strong>tacks in September 2001<br />

and subsequent anthrax <strong>at</strong>tacks, few hospitals<br />

considered it a priority to integr<strong>at</strong>e bioterrorist<br />

preparedness into their disaster plans,” Terndrup<br />

says. “Afterward, however, the challenge to educ<strong>at</strong>e<br />

hospital-based clinicians and infection-control<br />

practitioners to recognize and respond to a<br />

bioterrorist event took precedence.”<br />

The pilot study, funded in part by the Agency<br />

for Healthcare Research and Quality, aimed to<br />

streamline hospital preparedness efforts through<br />

the implement<strong>at</strong>ion <strong>of</strong> a screen-saver program as<br />

an educ<strong>at</strong>ional tool for clinicians. “Initi<strong>at</strong>ives to<br />

prepare hospital-based practitioners must fit<br />

among the demands <strong>of</strong> p<strong>at</strong>ient care, administr<strong>at</strong>ive<br />

duties, and continuing educ<strong>at</strong>ion within specialties,”<br />

Terndrup says. “The interactive screensaver<br />

program was designed with these consider<strong>at</strong>ions<br />

in mind.”<br />

The screen-saver program also may direct the<br />

user to access a Web site for additional bioterrorist<br />

inform<strong>at</strong>ion and Web-based learning modules<br />

relevant to the user’s particular specialty. The site,<br />

[www.bioterrorism.uab.edu], currently <strong>of</strong>fers<br />

nine continuing-educ<strong>at</strong>ion courses developed<br />

specifically for the following specialties: emergency<br />

medicine, radiology, p<strong>at</strong>hology, infection<br />

control, pedi<strong>at</strong>rics, family practice, internal medicine,<br />

and derm<strong>at</strong>ology.<br />

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