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Summer 2007 [pdf] - University of Kentucky - College of Pharmacy
Summer 2007 [pdf] - University of Kentucky - College of Pharmacy
Summer 2007 [pdf] - University of Kentucky - College of Pharmacy
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Page 1 <strong>of</strong> 5<br />
9/10/<strong>2007</strong><br />
July 13, <strong>2007</strong><br />
In this issue…<br />
• Message from the Chair<br />
• Groundbreaking for New UK <strong>College</strong> <strong>of</strong> <strong>Pharmacy</strong> Held<br />
• Hussain, Brouwer Honored as Outstanding UK Pharmaceutical Sciences Alumni<br />
• UK Researchers Find New Class <strong>of</strong> Nontoxic Cancer Treatments<br />
• Organic Solid State Chemistry Symposium Hosted by UK<br />
• Students Awarded Ph.D. During May Commencement<br />
• International Symposium on Microencapsulation is Sept. 9-12<br />
• Jay Attends Nano Conference in Beijing<br />
• Postdoctoral Pr<strong>of</strong>ile: Brett Jones<br />
• Program Helps Build UK Legacy Tradition<br />
• Four Faculty Honored with Teaching Awards<br />
• Freeman Receives Miles Award for Community Service<br />
Message from the Chair<br />
It was a busy spring semester at UK with the postgraduate conference and groundbreaking<br />
ceremony for the new pharmacy building. But it hasn’t seemed to slow down much now that it’s<br />
summertime.<br />
We currently have 18 students participating in the Pharmaceutical Sciences Undergraduate <strong>Summer</strong><br />
Research Program. The students are spending 10 weeks on campus being mentored by our faculty.<br />
In addition, we’re already planning for the fall as UK and AAPS will co-host the International<br />
Microencapsulation Conference bringing hundreds <strong>of</strong> scientists to Lexington. And we’re also<br />
preparing for a great new group <strong>of</strong> graduate students to arrive. In August, we’ll welcome 15 new<br />
students to the graduate program -- nine in the traditional pharmaceutical sciences track; five in the<br />
clinical and experimental therapeutics track; and our first student will be enrolled in the new<br />
pharmaceutical policy track.<br />
I hope you are having a great summer and please don’t forget our interest in sharing your alumni<br />
news.<br />
Sincerely,<br />
Patrick McNamara, Ph.D.<br />
Chair, Department <strong>of</strong> Pharmaceutical Sciences<br />
<strong>University</strong> <strong>of</strong> <strong>Kentucky</strong> <strong>College</strong> <strong>of</strong> <strong>Pharmacy</strong><br />
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Groundbreaking for New UK <strong>Pharmacy</strong> Building Held April 13
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Page 2 <strong>of</strong> 5<br />
9/10/<strong>2007</strong><br />
The <strong>University</strong> <strong>of</strong> <strong>Kentucky</strong> <strong>College</strong> <strong>of</strong> <strong>Pharmacy</strong> marked a significant milestone in the history and<br />
future <strong>of</strong> the <strong>College</strong> on April 13, as <strong>University</strong> and <strong>College</strong> <strong>of</strong>ficials held a ceremonial<br />
groundbreaking for a new 286,000 square-foot state-<strong>of</strong>-the art academic and research building.<br />
READ MORE<br />
For more information, visit the Building Update site at http://www.mc.uky.edu/pharmacy/building.html<br />
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Hussain, Brouwer Honored as Outstanding UK Pharmaceutical<br />
Sciences Alumni<br />
Kim Brouwer, Ph.D., and Munir Hussain, Ph.D., both 1983 UK graduates, were presented the<br />
inaugural Outstanding UK Pharmaceutical Sciences Alumni Award during a banquet April 20, held in<br />
conjunction with the UK Pharmaceutical Sciences Postgraduate Conference. READ MORE<br />
Postgraduate Conference Photo Gallery<br />
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UK Researchers Find New Class <strong>of</strong> Nontoxic Cancer Treatments<br />
A new class <strong>of</strong> compounds developed by <strong>University</strong> <strong>of</strong> <strong>Kentucky</strong> researchers shows promise as a<br />
nontoxic treatment <strong>of</strong> some cancers previously treated with toxic chemotherapy. In a study published<br />
in the April 30 issue <strong>of</strong> the academic journal Chemistry & Biology, UK pharmaceutical sciences<br />
graduate student Abby Ho mentored by assistant pr<strong>of</strong>essor Kyung-Bo Kim and ophthalmology and<br />
visual sciences assistant pr<strong>of</strong>essor Royce Mohan describe a compound that acts directly on LMP2, a<br />
component <strong>of</strong> the immune proteasome variant that has been identified abundantly expressed in<br />
certain types <strong>of</strong> tumors, including some prostate cancers. READ MORE<br />
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Organic Solid State Chemistry Symposium Hosted by UK<br />
The Midwest Organic Solid State Chemistry Symposium (MOSSC) was held for the first time in<br />
Lexington on June 8-9. Conference chairs for the event were Tonglei Li, Ph.D., assistant pr<strong>of</strong>essor<br />
in the UK Department <strong>of</strong> Pharmaceutical Sciences, and Carol Brock, Ph.D., pr<strong>of</strong>essor, in the UK<br />
Department <strong>of</strong> Chemistry. More than 40 participants from 10 institutions attended the event.<br />
MOSSCS provides opportunities to exchange ideas and research results pertaining to the organic<br />
solid state in an informal atmosphere with an emphasis on presentations by graduate students and<br />
postdoctoral associates. Invited lecturers and reports <strong>of</strong> research on organic materials dealing with<br />
crystal engineering, mixed crystals, polymorphism, solid state synthesis and reactivity, host-guest<br />
chemistry, crystal growth, optical behavior, transport properties, pharmaceuticals, molecular<br />
recognition, critical behavior and related properties all are commonly presented at the MOSSC<br />
Symposium. For more information, contact Dr. Li at Tonglei@uky.edu.<br />
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11 Students Awarded Ph.D. During May Commencement
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Page 3 <strong>of</strong> 5<br />
9/10/<strong>2007</strong><br />
The <strong>University</strong> <strong>of</strong> <strong>Kentucky</strong> <strong>College</strong> <strong>of</strong> <strong>Pharmacy</strong> honored 11 graduate students during the <strong>2007</strong><br />
Graduation Recognition Ceremony held May 4 at the UK Singletary Center for the Arts. Those<br />
receiving degrees and their current positions:<br />
Joshua T. L. Ayers, Ph.D. (May 11, 2006)<br />
“Synthesis and Evaluation <strong>of</strong> Pyridinium Derivatives as Central Nervous System Nicotinic<br />
Acetylcholine Receptor Ligands”<br />
Mentor: Peter A. Crooks, Ph.D.<br />
Current position: Senior Scientist, AstraZeneca, Wilmington, Del.<br />
Tao Liu, Ph.D. (May 30, 2006)<br />
“Generating Novel Derivatives <strong>of</strong> the Anticancer Agent Gilvocarcin by Combinatorial Biosynthesis”<br />
Mentor: Jürgen Rohr, Ph.D.<br />
Current position: Postdoc in Dr. Ben Shen’s lab, <strong>University</strong> <strong>of</strong> Wisconsin-Madison <strong>College</strong> <strong>of</strong><br />
<strong>Pharmacy</strong><br />
Korie G. Counts, Ph.D. (June 2, 2006)<br />
“Mechanistic and Structural Investigation <strong>of</strong> Yersinia Pestis Arginine Decarboxylase”<br />
Mentor: Marcos A. Oliveira, Ph.D.<br />
Current position: Technology Manager, Center for Technology Commercialization, Cincinnati<br />
Children’s Hospital Medical Center<br />
Jigna D. Patel, Ph.D. (June 21, 2006)<br />
“Pharmaceutically Engineered Nanoparticles For Enhancing Immune Responses to HIV-1 Tat and<br />
Gag p24 Proteins”<br />
Mentor: Russell J. Mumper, Ph.D.<br />
Current position: Senior Scientist, Research Formulations Department, Pfizer, Groton, Conn.<br />
Joseph P. Medendorp, Ph.D. (June 29, 2006)<br />
“Chemometrics, Spectrometry, and Sensors for Integrated Sensing and Processing: Advancing<br />
Process Analytical Technology”<br />
Mentor: Robert A. Lodder, Ph.D.<br />
Current position: Research Scientist, Coldstream Laboratories Inc. and AllTranz, Lexington, Ky.<br />
Kalyani G. Bharadwaj, Ph.D. (July 21, 2006)<br />
“Effect <strong>of</strong> Local and Systemic Angiotensin II (ANGII) on Adipocyte Growth and Differentiation”<br />
Mentor: Lisa A. Cassis, Ph.D.<br />
Bethel V. Sharma, Ph.D. (June 15, 2006)<br />
“Hinge Motion Protein-Based Fluorescence Assays for Biosensing and Biomolecular Screening<br />
Applications”<br />
Mentor: Sylvia Daunert, Ph.D.<br />
Current position: Research Scientist, Analytical Biological Services, Landsdale, Penn.<br />
Li Li, Ph.D. (September 18, 2006)<br />
“Hepatic Cytochrome P450 Reductase-Null Mice as an Animal Model to Study Electron Transfer<br />
Pathways in Cholesterol Synthesis and CYP2E1-Mediated Drug Metabolism”<br />
Mentor: Todd D. Porter, Ph.D.<br />
Current position: Senior Chemist, Dow Chemical China Company Ltd.<br />
Graduation Photo Gallery<br />
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International Symposium on Microencapsulation is Sept. 9-12
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Page 4 <strong>of</strong> 5<br />
9/10/<strong>2007</strong><br />
Pharmaceutical scientists from around the world will be traveling to Lexington in September for the<br />
16th International Symposium on Microencapsulation. The biennial event set for Sept. 9-12 was last<br />
held in the U.S. in 1995. It is co-sponsored by the American Association <strong>of</strong> Pharmaceutical Scientists<br />
(AAPS) and the UK <strong>College</strong> <strong>of</strong> <strong>Pharmacy</strong>. READ MORE<br />
In addition, registration, directions and information on accommodations are available at the<br />
Microencapsulation Symposium homepage at http://www.mc.uky.edu/cpst/micro16.<br />
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Jay Attends Nano Conference in Beijing<br />
Michael Jay, Ph.D., pr<strong>of</strong>essor, attended the ChinaNANO<strong>2007</strong>, the International Conference on<br />
Nanoscience and Technology, held June 4-6, in Beijing, China. He presented, “Dexamethasone<br />
Palmitate Nanoparticles Prepared by Nanotemplate,” during the Nanobiology and Nanomedicine<br />
panel session. READ MORE<br />
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Postdoctoral Pr<strong>of</strong>ile: Brett Jones<br />
Brett Jones, Ph.D., is a postdoctoral scholar in the UK Department <strong>of</strong> Pharmaceutical Sciences with<br />
Penni Black, Ph.D, assistant pr<strong>of</strong>essor. His research involves analyzing the expression <strong>of</strong> various<br />
members <strong>of</strong> the mitogen-activated protein kinase (MAPK) signaling pathway in non-small cell lung<br />
cancer cell lines.<br />
Jones is a native <strong>of</strong> Adelaide, Australia, and graduated in 1994 with a bachelor’s degree in<br />
microbiology and biomedicine from The Flinders <strong>University</strong> <strong>of</strong> South Australia, and a bachelor’s<br />
degree in developmental biology in 1996, also from Flinders <strong>University</strong>. In May 1996, he joined the<br />
graduate program at the School <strong>of</strong> <strong>Pharmacy</strong> and Medical Sciences at The <strong>University</strong> <strong>of</strong> South<br />
Australia. His research project, entitled, “The molecular characterization <strong>of</strong> xenobiotic-metabolising<br />
enzymes in Australian marsupials,” provided the first available information on the identification and<br />
relative expression <strong>of</strong> the cytochrome P450 and UDP-glucuronosyltransferase enzyme families in<br />
several adult and neonatal Australian marsupial species. His thesis work concluded with the<br />
successful cloning <strong>of</strong> two cytochrome P450 CYP2C cDNA sequences from the Koala (Phascolarctos<br />
cinereus), designated CYP2C47 and CYP2C48. The sequences represented the first two CYP450<br />
cDNAs to be cloned for any Australian marsupial species. Prior to joining Dr Black’s lab, Jones<br />
completed an initial postdoctoral fellowship in the UK Graduate Center for Toxicology with Pr<strong>of</strong>essor<br />
Mary Vore.<br />
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Ph.D. Program Helps Build UK Legacy Tradition<br />
In the fall <strong>of</strong> 1981, when Joe Fleishaker was a senior in the pharmacy program at Duquesne<br />
<strong>University</strong> in Pittsburgh, he came to Lexington to visit the <strong>University</strong> <strong>of</strong> <strong>Kentucky</strong> while checking out<br />
graduate programs. At the time, he had no way <strong>of</strong> knowing the lifelong connection he'd have with UK<br />
and the Bluegrass. READ MORE<br />
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Four Faculty Honored with Teaching Awards
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Page 5 <strong>of</strong> 5<br />
9/10/<strong>2007</strong><br />
Four UK Department <strong>of</strong> Pharmaceutical Sciences faculty members have been recognized for<br />
outstanding contributions in the classroom during the past academic year.<br />
Peter Crooks, Ph.D., pr<strong>of</strong>essor, and Tonglei Li, Ph.D., assistant pr<strong>of</strong>essor, were awarded the<br />
Robert A. Blouin Excellence in Graduate Education Awards. Todd Porter, Ph.D., associate<br />
pr<strong>of</strong>essor, and Paul Bummer, Ph.D., associate pr<strong>of</strong>essor, received the Robert A. Blouin Excellence<br />
in Pharmaceutical Pr<strong>of</strong>essional Education Awards. The awards honor Blouin, who served as a UK<br />
<strong>College</strong> <strong>of</strong> <strong>Pharmacy</strong> faculty member beginning in 1978 until 2003 when he retired as the college’s<br />
associate dean for research and graduate education. He currently serves as dean at the <strong>University</strong> <strong>of</strong><br />
North Carolina School <strong>of</strong> <strong>Pharmacy</strong>.<br />
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Freeman Receives Miles Award for Community Service<br />
It was seven years ago when UK <strong>College</strong> <strong>of</strong> <strong>Pharmacy</strong> faculty member Dr. Patricia Rippetoe<br />
Freeman (B.S, 1987, Ph.D., 1991) learned two <strong>of</strong> her children were gradually losing their hearing.<br />
Utilizing her instincts not only as a mother, but one with a Ph.D., she did what she knew best –<br />
research. Her investigation began to learn as much as she could to help her young sons, Kenneth<br />
and Edward. READ MORE<br />
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Email addresses needed<br />
We are trying to catch up with former graduate students, postdoctoral fellows and former<br />
faculty. Please send current contact information <strong>of</strong> folks you knew at UK and are still in close contact<br />
with to pschair@email.uky.edu and <strong>of</strong> course please forward your friends and colleagues this<br />
newsletter.<br />
UK Pharmaceutical Sciences e-News is an electronic publication from the <strong>University</strong> <strong>of</strong> <strong>Kentucky</strong> <strong>College</strong> <strong>of</strong> <strong>Pharmacy</strong><br />
Department <strong>of</strong> Pharmaceutical Sciences. You are currently subscribed to receive this publication. If you received this<br />
newsletter and would like to UNSUBSCRIBE OR if you were forwarded the newsletter by a friend and would like to be a<br />
SUBSCRIBER, please send an email to Kristi Lopez at kwlope0@email.uky.edu.
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