Sample Size and Power
Sample Size and Power
Sample Size and Power
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Phase I<br />
Enroll 3 people<br />
0/3 DLT 1/3 DLT 2 or 3 / 3 DLT<br />
Escalate to<br />
new dose<br />
Enroll 3 more<br />
at same dose<br />
0/new 3 DLT 1 or more /<br />
new 3DLT<br />
Escalate to<br />
new dose<br />
Stop<br />
Stop<br />
Drop<br />
down<br />
dose;<br />
start<br />
over