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Evolution<br />
and 3d<br />
structure<br />
Isocitrate<br />
dehydrogenase:<br />
The distance from<br />
the active site<br />
(yellow) determines<br />
the rate of evolution<br />
Dean, A. M. and G. B. Golding. 2000,<br />
Enzyme evolution explained (sort of),<br />
Pacific Symposium on Bioinformatics<br />
2000