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NHMRC Glaucoma Guidelines - ANZGIG

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<strong>NHMRC</strong> GUIDELINES FOR THE SCREENING, PROGNOSIS, DIAGNOSIS, MANAGEMENT AND PREVENTION OF GLAUCOMA<br />

Chapter 1 – Recommendations and Evidence statements<br />

Recommendation<br />

• Survey for glaucoma<br />

particularly in<br />

patients greater<br />

than 50 years of<br />

age, with any myopia,<br />

with abnormal blood<br />

pressure, with a history<br />

of migraine, with diabetes,<br />

with peripheral vasospasm,<br />

with eye injury and/or<br />

with ongoing steroid use.<br />

• Monitor for glaucoma<br />

particularly in<br />

patients greater<br />

than 70 years<br />

of age, with<br />

IOP >21 mmHg,<br />

large and/or asymmetric<br />

cup-to-disc ratio<br />

(compared with disc<br />

size), disc haemorrhage,<br />

and thin central<br />

corneal thickness.<br />

Evidence Statements<br />

Risk factors identified from patient history –<br />

Intraocular pressure<br />

Evidence strongly supports the assessment of intraocular<br />

pressure in all individuals with suspected glaucoma, as it<br />

is a significant risk factor for the development of all forms<br />

of glaucoma.<br />

Evidence strongly supports using 21mmHg as the upper<br />

limit for usual intraocular pressure.<br />

Risk Factors identified from patient history –<br />

Alterations in cup:disc ratio and asymmetry<br />

Evidence supports the assessment of cup:disc ratio, and<br />

cup:disc ratio asymmetry, when assessing the risk of<br />

glaucomatous damage occurring.<br />

Risk Factors identified from patient history –<br />

Optic disc haemorrhage<br />

Evidence supports past signs, or current presence, of<br />

optic disc haemorrhages as significant risk factors for the<br />

development and progression of glaucoma.<br />

Evidence supports more aggressive treatment of patients<br />

with ocular hypertension, or glaucoma, who present with<br />

optic disc rim haemorrhages, or evidence of past optic disc<br />

rim haemorrhages.<br />

Risk Factors identified from patient history –<br />

Central corneal thickness<br />

Evidence supports the assessment of central corneal<br />

thickness in patients with ocular hypertension, or suspected<br />

cases of glaucoma.<br />

Risk factors for specific glaucoma types and stages –<br />

Angle closure<br />

Expert/consensus opinion suggests that hypermetropia,<br />

family history of angle closure, advancing age, female<br />

gender, Asian descent and shallow anterior chamber<br />

are risk factors for the development of angle closure,<br />

and angle closure glaucoma.<br />

Risk factors for specific glaucoma types and stages –<br />

Progression of established glaucoma<br />

Evidence indicates that factors associated with greater risk<br />

of glaucoma progression include elevated/fluctuating<br />

intraocular pressure, optic disc haemorrhage, increased<br />

severity of glaucomatous disc damage and very low blood<br />

pressure. These patients require greater reduction in<br />

intraocular pressure.<br />

Evidence<br />

Statement<br />

Grade<br />

A<br />

A<br />

C<br />

B<br />

B<br />

B<br />

B<br />

14 National Health and Medical Research Council

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