A Genome-Wide Association Study of Drug-Induced Liver ... - AASLD

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A Genome-Wide Association Study of Drug-Induced Liver ... - AASLD

Isoniazid-induced Liver Injury

• Idiosyncratic, suspected genetic predisposition

• (Weak) evidence for familial clustering

• Essential component of treatment for

tuberculosis

Liver injury due to isoniazid (relatively)

common and severe

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