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The Maximum Expiratory Flow-Volume Curve with Air and a Low ...

The Maximum Expiratory Flow-Volume Curve with Air and a Low ...

Table

Table 1-Maximum Flow rates at 50% Vital Capacity (V5o), L/Sec Subject No. 1 2 3 4 5 6 7 8 9 10 Total Mean Day I AM Mean 8.13 5.73 5.86 3.42 3.98 501 4.72 5.86 3.70 SD 0.33 0.24 0.26 0.11 0.16 0.09 0.14 0.13 0.31 PM Mean 6.61 4.68 5.76 3.29 3.41 4.72 5.08 6.47 4.14 Day 2 SD 0.12 0.08 0.17 0.20 0.11 0.16 0.19 0.21 0.20 AM Mean 7.30 5.01 5.33 3.34 3.67 4.52 4.76 6.56 3.34 SD 0.37 0.15 0.17 0.13 0.09 0.16 0.14 0.21 0.11 PM Mean 6.51 4.82 5.38 3.09 3.39 4.54 4.59 6.50 3.66 Day 3 SD 0.17 0.19 0.20 0.12 0.17 0.12 0.14 0.13 0.19 AM Mean 7.52 5.01 4.46 3.06 3.33 4.52 4.37 6.49 3.60 SD 0.30 0.14 0.26 0.11 0.09 0.12 0.11 0.15 0.15 PM Mean 7.02 5.03 4.51 3.17 3.66 3.74 5.21 6.84 4.44 SD 0.13 0.11 0.12 0.13 0.07 0.13 0.21 0.13 0.12 Day 31 AM Mean 7.69 5.10 4.99 3.30 3.59 5.08 4.73 5.84 3.98 SD 0.32 0.09 0.12 0.10 0.15 0.16 0.07 0.24 0.34 PM Mean 8.47 5.40 5.91 3.53 3.38 5.32 4.34 6.03 3.56 SD 0.41 0.09 0.23 0.05 0.11 0.19 0.27 0.22 0.17 Total Mean 7.41 5.10 5.27 3.28 3.55 4.68 4.73 6.32 3.80 SD 0.71 0.36 0.57 0.19 0.24 0.47 0.33 0.39 0.39 AM Mean 7.66 5.21 5.16 3.28 3.64 4.78 4.65 6.19 3.66 PM Mean 7.15 4.98 5.39 3.27 3.46 4.58 4.81 6.46 3.95 3.48 4.99 0.17 1.42 3.83 4.80 0.13 1.14 3.32 4.72 0.10 1.34 3.42 4.59 0.12 1.20 3.32 4.57 0.10 1.39 3.28 4.69 0.07 1.31 3.61 4.79 0.14 1.26 3.72 4.97 0.16 1.54 3.50 4.76 0.23 1.33 3.43 4.77 3.56 4.76 Table 2-Increase in Maximal Flow at 50% Vital Capacity Breathing Helium-Oxygen (J50) % Subject No. 1 2 3 4 5 6 7 9 10 Day 1 AM Mean 32.5 44.6 36.4 32.9 64.9 37.9 43.4 36.1 64.0 SD 18.3 16.5 2.8 8.2 9.3 2.8 3.2 7.7 12.7 PM Mean 76.7 60.7 45.1 28.6 82.6 56.7 30.1 37.2 34.3 SD 5.8 8.2 7.7 4.3 11.8 17.7 3.8 8.8 4.4 Total Mean 43.6 13.9 50.2 13.3 Day 2 AM Mean 20.7 39.4 39.0 44.3 78.6 53.4 47.1 37.9 35.9 SD 5.7 5.4 5.9 4.4 7.7 6.4 4.4 4.2 4.1 PM Mean 37.0 56.1 18.0 27.0 56.0 52.3 69.1 31.8 58.1 SD 5.2 12.1 10.4 2.7 7.2 4.4 3.4 5.0 6.5 Day 3 AM Mean 21.2 49.2 64.6 27.0 48.4 52.1 41.9 48.1 53.2 SD 5.2 4.3 9.7 2.7 4.0 3.4 2.3 5.7 3.6 PM Mean 79.6 61.4 73.3 35.3 59.3 76.4 35.2 38.9 38.7 SD 8.0 6.7 6.2 3.8 3.4 25.7 3.4 5.2 5.4 44.0 14.5 45.1 13.3 45.1 16.8 55.4 17.8 Day 31 AM Mean 60.8 65.9 56.0 30.8 49.4 54.4 28.4 49.3 47.4 SD 8.3 8.4 5.4 4.1 6.6 8.1 5.6 5.4 3.6 PM Mean 34.9 54.6 26.2 23.8 54.2 44.4 54.4 48.4 51.7 SD 6.3 3.9 5.1 2.6 4.7 4.5 4.0 5.2 2.0 Total Mean 45.4 54.0 44.8 31.2 61.7 53.5 43.7 41.0 47.9 SD 23.8 12.1 19.0 7.3 13.9 15.4 13.2 8.5 11.7 AM Mean 33.8 49.8 49.0 33.7 60.3 49.5 40.2 42.9 50.1 PM Mean 57.0 58.2 40.7 28.7 63.0 57.5 47.2 39.1 45.7 49.2 19.1 43.6 16.7 47.0 16.9 45.5 48.6 24 BEREND ET AL CHEST, 80: 1, JULY, 1981 Downloaded From: http://publications.chestnet.org/ on 05/16/2014

Table 3-Volume at which Curves Breathing Air and Helium-Oxygen First Meet (VisoV), % VC Subject No. Day 1 1 2 3 4 5 6 7 9 10 Total Mean AM Mean 18.7 24.0 20.8 11.4 10.8 5.1 1.3 14.8 1.7 12.1 SD 14.0 5.1 4.2 6.1 9.5 2.9 2.4 2.0 2.6 7.5 PM Mean 6.4 12.6 6.9 15.1 8.6 22.2 4.2 20.7 15.6 12.5 Day 2 SD 4.1 3.6 6.0 2.9 6.1 4.4 3.8 3.7 1.8 3.6 AM Mean 18.1 11.4 14.8 13.3 5.2 11.0 6.6 10.4 21.8 12.5 SD 2.7 2.4 6.7 1.9 2.2 3.8 4.1 4.8 2.1 1.2 PM Mean 26.1 15.1 30.1 15.2 11.2 12.3 0.8 12.4 10.0 14.8 SD 7.4 2.8 9.2 1.6 8.9 3.3 1.7 8.6 6.7 6.6 Day 3 AM Mean 15.9 9.6 17.7 15.3 20.3 13.8 6.4 8.3 10.6 13.1 SD 6.5 4.5 .5 1.3 12.3 2.3 3.8 5.2 2.0 2.9 PM Mean 1.7 10.0 7.4 17.3 3.2 7.9 9.9 4.6 6.2 7.6 Day 31 SD 2.1 6.2 3.1 4.2 3.0 6.4 2.1 3.8 5.6 4.5 AM Mean 12.6 3.3 10.2 18.6 14.7 1.9 32.4 10.2 11.6 12.8 SD 3.9 3.3 2.3 3.2 3.4 3.0 2.1 3.5 1.7 5.5 PM Mean 10.6 8.9 21.2 13.2 9.6 6.3 8.7 8.2 20.0 11.9 SD 4.8 4.0 3.0 2.3 6.2 9.6 3.8 7.9 8.3 4.8 Total Mean 13.8 11.9 16.1 14.9 10.5 10.1 8.8 11.2 12.2 12.2 SD 9.6 6.9 9.1 3.8 8.5 7.6 9.9 6.9 7.7 8.3 AM Mean 16.3 12.1 15.9 14.7 12.8 7.9 11.7 10.9 11.4 12.6 PM Mean 11.2 11.6 16.4 15.2 8.1 12.2 5.9 11.5 12.9 11.7 The tests were performed in the morning (between 9 all the effects that were statistically significant and 10 AM) and the afternoon (between 4 and 5 PM) on involved the subject variable. The measurement of three successive days and again on one day a month later. Viso differed from the other two in that, in addi- The curves were coded and analyzed independently on three separate occasions by each of three experienced ob- tion, an observer main effect was found to be staservers who measured the V50 and superimposed the air tistically significant. This means that across all suband He-02 curves, matched at residual volume, on tracing jects and the given days and the given times, for paper to obtain the and VisoT. Due to a technical some observers, the measurements were consistently problem, one subject did not breathe the He-02 mixture on the day 1 morning tests, and the readings for V50 and higher than for others. In general, the effects in- VisoV for this subject were treated as missing values, #{237}a volving observer differences were of much lower for the 5O and Viso the results of nine subjects only magnitude than the others, since their variations were analyzed. A full description of the statistical methods occurred on the same test while the day-to-day diiis given in the Appendix. ferences involved a repetition of testing. RESULTS The main effects of day and time and the two- way interaction between day and time were not The results of the readings for the V50, V5o, and statistically significant for any of the measurements. Viso are given in Tables 1 to 3. For the to and Thus, it was not found that on the average the Table 4-Estimates of Hierarchal Variation Components Measurement 2 row2 cIT2 lTD2 as2 \?& 0.017 (0.OlO)t 0.018 (0.010) 0.122 (0.070) 0.04 (0.024) 1.74 LW50 5.042 (0.100) 23.167 (0.463) 192.550 (3.846) . . . 50.071 Viso1 21.836 (68.025) 4.908 (15.290) 39.626 (123.445) 2.355 (7.336) 0.321 *q 2=variation between different readings by same observer on same test pooled over all observers and all tests. ao = additional variation due to observer differences on same test pooled over all tests. ITT2 =additional variation due to the test being repeated pooled over all days and all subjects. CD2 =additional variation due to the repeated tests involving different days pooled over all subjects. a2 =additional variation due to the tests being carried out on different subjects. tNumbers in parentheses are ratios to u2. CHEST, 80: 1, JULY, 1981 MAXIMUM EXPIRATORY FLOW-VOLUME CURVE 25 Downloaded From: http://publications.chestnet.org/ on 05/16/2014

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