Artesunate versus quinine for severe malaria in children - iDOC Africa
Clinical questions • Specific clinical questions were identified using the PICOTS format. • We performed a comprehensive search on PubMed and the Cochrane library to compare the outcomes of patients. • The quality of evidence was assessed using the GRADE approach.
Outcomes considered Population Children under 15 years of age Intervention Artesunate Comparator Quinine Outcomes Death, neurological sequelae, hypoglycaemia episodes, parasite and fever clearance times. Setting Malaria endemic areas