Artesunate versus quinine for severe malaria in children - iDOC Africa
Summary of findings • We found one Cochrane review (Sinclair et. al 2012) and no further RCTs. • Four trials in the Cochrane review met our inclusion criteria. • We found one study that examined the cost effectiveness of the two interventions.
Quality of evidence Quality assessment Quality Importance Studies Design Limitations in study methods Outcome: Death 4 RCTs None ⊕⊕⊕⊕ HIGH CRITICAL • RRR 24% (10% to 35%) • Intervention beneficial – supported by evidence.