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Clinical Research Experience

Clinical Research Experience

Minimal impact of adding

Minimal impact of adding false events or of missing real events Active (10,000) Control (10,000) OR (& 95%CI) Z score True events 800 1000 0.78 (0.71-0.86) 4.9 Extra false events (evenly distributed) + 10% 890 1090 0.80 (0.73-0.88) 4.7 + 20% 980 1180 0.81 (0.74-0.89) 4.6 Missing real events (unevenly distributed) - 10% 720 900 0.78 (0.71-0.87) 4.7 - 20% 640 800 0.79 (0.71-0.88) 4.4

HPS: Effects of simvastatin-allocation on ADJUDICATED major vascular events

Clinical Research Experience
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