28.11.2014 Views

2007 Annual Report - College of Pharmacy - The Ohio State University

2007 Annual Report - College of Pharmacy - The Ohio State University

2007 Annual Report - College of Pharmacy - The Ohio State University

SHOW MORE
SHOW LESS

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

Academic Divisions, 2006-<strong>2007</strong><br />

Division <strong>of</strong> Medicinal Chemistry and Pharmacognosy<br />

Li, Pui-Kai<br />

Brueggemeier, Robert W.<br />

Carcache de-Blanco, Esperanza<br />

Chen, Ching-Shih<br />

Curley, Robert W.<br />

Kinghorn, A Douglas<br />

Li, Chenglong<br />

Tjarks, Werner<br />

Werbovetz, Karl A.<br />

Whetstone, Jennifer L.<br />

Cassady, John M.<br />

Doskotch, Raymond<br />

Jagadeesh, Jogikal<br />

Olson, Carter<br />

Robertson, Larry<br />

Soloway, Albert<br />

Associate Pr<strong>of</strong>essor and Chair<br />

Pr<strong>of</strong>essor and Dean<br />

Assistant Pr<strong>of</strong>essor (joint, <strong>Pharmacy</strong> Practice and Admin.)<br />

Pr<strong>of</strong>essor<br />

Pr<strong>of</strong>essor<br />

Pr<strong>of</strong>essor and Jack L. Beal Chair<br />

Assistant Pr<strong>of</strong>essor<br />

Assistant Pr<strong>of</strong>essor<br />

Assistant Pr<strong>of</strong>essor<br />

Visiting Assistant Pr<strong>of</strong>essor<br />

Emeritus Pr<strong>of</strong>essor and Dean<br />

Pr<strong>of</strong>essor Emeritus<br />

Pr<strong>of</strong>essor Emeritus<br />

Pr<strong>of</strong>essor Emeritus<br />

Pr<strong>of</strong>essor Emeritus<br />

Emeritus Pr<strong>of</strong>essor and Dean<br />

<strong>The</strong> Division <strong>of</strong> Medicinal Chemistry and Pharmacognosy is composed <strong>of</strong> faculty members<br />

with diversified research interests representing synthetic organic,<br />

natural products, and biological chemistry. Research in medicinal<br />

chemistry emphasizes drug design and includes:<br />

❖ the synthesis <strong>of</strong> organic medicinal products,<br />

❖ elucidation <strong>of</strong> the biochemistry <strong>of</strong> medicinal agents,<br />

❖ examination <strong>of</strong> the relationship <strong>of</strong> chemical structure to<br />

biological activity, qualitative and quantitative analysis <strong>of</strong><br />

drugs and related products, application <strong>of</strong> computational<br />

chemistry to drug design.<br />

Research in pharmacognosy emphasizes drug discovery and<br />

encompasses:<br />

❖ the isolation and structure determination <strong>of</strong><br />

pharmacologically active natural products from plants and<br />

microbes,<br />

❖ studies on the structure and biochemistry <strong>of</strong> biological products,<br />

❖ examination <strong>of</strong> the biosynthesis <strong>of</strong> natural products,<br />

❖ evaluation <strong>of</strong> the biochemical effects <strong>of</strong> these active constituents.<br />

Pui-Kai (Tom) Li<br />

Chair<br />

Werner Tjarks was born and<br />

raised in Bremen Germany, a<br />

northern seaport town. Werner’s<br />

studies in chemistry, drug design<br />

and environmental aspects in<br />

Germany led him to the US in the<br />

early nineties to work with<br />

Dr. Albert Soloway in a postdoctoral<br />

position. In 1997 he took<br />

a position as a Research Scientist<br />

and now as a faculty member,<br />

focuses in the area <strong>of</strong> cancer<br />

research, specifically nucleoside<br />

chemistry. Wener is attempting to<br />

apply this science to the<br />

development <strong>of</strong> anti-cancer drugs.<br />

His research team is using<br />

neutron-capture therapy to treat<br />

cancer. Werner recalls that Dr.<br />

Soloway was never too busy to<br />

talk with any <strong>of</strong> his colleagues.<br />

His <strong>of</strong>fice door was always open<br />

giving his research group the<br />

accessibility to him so critical to<br />

their success in the lab.<br />

Werner finds the academic<br />

climate at OSU conducive to<br />

collaboration and has forged<br />

important relationships with<br />

colleagues from the <strong>College</strong> <strong>of</strong><br />

Medicine and the Veterinary<br />

Biological Science Department.<br />

This year, Dr. Tjarks was<br />

promoted to Associate Pr<strong>of</strong>essor<br />

<strong>of</strong> <strong>Pharmacy</strong>.<br />

Karl Werbovetz’s experience at the<br />

Walter Reed Army Institute <strong>of</strong><br />

Research gave him the opportunity to<br />

see drug development in action and<br />

formed his ideas for current<br />

programs and collaborations here at<br />

OSU. His research now is in the area<br />

<strong>of</strong> anti-parasitic drug discovery and<br />

development. A major problem in<br />

developing countries, lethal<br />

parasites, carried by insects, are a<br />

major cause <strong>of</strong> death. As there is no<br />

financial incentive to develop drugs<br />

in this area, Karl works with NIH,<br />

WHO and the Bill and Melinda Gates<br />

Foundation to fund his research.<br />

Karl joined our <strong>College</strong> in 2000 and<br />

found a new commitment to<br />

infectious disease research here at<br />

OSU. His collaborations with<br />

colleagues across campus are<br />

building a bridge between <strong>Pharmacy</strong><br />

and other health units to continue<br />

this important work in the area <strong>of</strong><br />

infectious disease.<br />

From a small town in upstate<br />

New York (Holland Patent), Karl is<br />

happy to have found a home at <strong>Ohio</strong><br />

<strong>State</strong>, both pr<strong>of</strong>essionally and<br />

personally. He and his wife, Julie,<br />

are raising their family <strong>of</strong> 3 (Luke,<br />

Ben and Graham) in Worthington.<br />

This year, Dr. Werbovetz was<br />

promoted to Associate Pr<strong>of</strong>essor <strong>of</strong><br />

<strong>Pharmacy</strong>.<br />

21

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!