2007 Annual Report - College of Pharmacy - The Ohio State University

Chin, Y.-W., H.-A. Jung, Y. Liu, B.-N. Su, J.A. Castoro, W.J. Keller, M.A. Pereira, and A.D. Kinghorn.
Anti-oxidant constituents of the roots and stolons of licorice (Glycyrrhiza glabra). J. Agric. Food Chem., 2007,
55, 4691-4697.
Kinghorn, A.D. and N.-C. Kim. “Discovering New Natural Sweeteners,” in Optimising Sweet Taste in Foods, ed.
W. Spillane, Woodhead Publishing Ltd./CRC Press, Cambridge, U.K., 2006, pp. 292-306.
Kim, S., A.A. Salim, S.M. Swanson, and A.D. Kinghorn. Potential of cyclopenta[b]benzofurans from Aglaia
species in cancer chemotherapy. Anticancer Agents Med. Chem. (formerly Curr. Med. Chem. - Anticancer Agents),
2006, 6, 319-345.
Jiang, Z.; Georgel, P.; Li, C.; Choe, J.; Crozat, K.; Rutschmann, S.; Du, X.; Bigby, T.; Mudd, S.; Sovath, S.;
Wilson, I. A.; Olson, A. and Beutler B. “Details of Toll-like receptor:adapter interaction revealed by germ-line
mutagenesis”. Proc. Nat. Acad. Sci. 2006, 103: 10961-10966.
Division of Pharmaceutics
Kosarek, CE, Hu X, Couto CG, Kisseberth WC, Green E, Au JL-S, Wientjes, MG. Phase I evaluation of lowdose
suramin as chemosensitizer of doxorubicin in dogs with naturally occurring cancers. J. Vet. Int. Med., J Vet.
Intern. Med., 20:1172-1177, 2006
Lu D, Wientjes MG, Lu Z, and Au JL-S. Tumor priming enhances delivery and efficacy of nanomedicines.
J Pharmacol. Exp. Ther., 322:80-88, 2007.
Hu L, Au JL-S, and Wientjes MG. Computational modeling to predict effect of treatment schedule on drug
delivery to prostate in humans. Clin. Cancer Res, 13:1278-1287, 2007.
Cheng H, Liu Z, Blum W, Byrd J, Klisovic R, Grever MR, Marcucci G, Chan KK. Quantification of Valproic
Acid and its Metabolite 2-propyl-4-pentenoic Acid in Human Plasma Using HPLC-MS/MS. J Chrom B, 2006.
Wei X, Dai G, Liu Z, Cheng H, Xie Z, Marcucci G, Chan KK. In vivo and in vitro Metabolism of GTI-2040, a
Phosphorothioate Oligonucleotide Antisense Targeting Ribonucleotide Reductase, Using Ion-pair Reversed Phase
HPLC Coupled with Electrospray Ion-trap Mass Spectrometry. AAPSJ, 8(4) article 84, 2006.
Fang L, Battisti RF, Cheng H, Reigan P, Xin Y, Shen J, Ross D, Chan KK, Martin EW, Wang PG, and Sun D.
Enzyme Specific Activation of Benzoquinone Ansamycin Prodrugs using HuCC49 CH2-ß Galactosidase
Conjugates. J Med Chem 49(21): 6290-6297, 2006.
Stram DO, Yuan J-M, Chan KK, Gao Y-T, Ross RK, Yu MC. Beta-cryptoxanthin and Lung Cancer in Shanghai,
China -an Examination of Potential Confounding with Cigarette Smoking Using Urinary Cotinine as a
Biomarker or True Tobacco Exposure. Nutrition and Cancer, 57(2), 2006.
Shah MH, Binkley P, Chan KK, Xiao J, Arbogast D, Collamore M, Farra Y, Young D, Wright J, and Grever M.
Cardiotoxicity of Histone Deacetylase Inhibitor Depsipeptide in Patients with Metastic Neuroendocrine Tumors.
Clin Cancer Res 12: 3997-4003, 2006.
Wei X, Dai G, Marcucci G, Liu Z, Hoyt D, Blum W, and Chan KK. A Specific Picomolar Hybridization-Based
ELISA Assay For The Determination Of Phosphorothioate Oligonucleotides in Plasma and Cellular Matrices.
Pharm Res 23(6):1251-1264, 2006.
Liu Z, Xie Z, Liu S, Blum W, Perrotti D, Paschka P, Klisovic R, Byrd JC, Chan KK, and Marcucci G.
Characterization of in vitro and in vivo hypomethylating effect of decitabine in acute myeloid leukemia by a
rapid, specific and sensitive LC-MS/MS method. Nucleic Acid Res. 35(5).
Liu S, Klisovic RB, Vukosavljevic T, Yu J, Paschka P, Huynh L, Pang J, Liu Z, Blum W, Chan KK, Perrotti D and
Marcucci G. Targeting AML1/ETO-HDAC repressor complex: a novel mechanism of valproic acid mediated gene
expression and cellular differentiation in AML-ETO-positive acute myeloid leukemia cells. J. Pharmacol. Exp.
Therap.
35