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Kernel Methods for Pattern Analysis John Shaw-Taylor University of Southampton & Nello Cristianini University of Bristol Kernel methods provide a powerful and unified framework for pattern discovery, motivating algorithms that can act on general types of data (e.g. strings, vectors or text) and look for general types of relations (e.g. rankings, classifications, regressions, clusters). The application areas range from neural networks and pattern recognition to machine learning and data mining. This book, developed from lectures and tutorials, fulfils two major roles: firstly it provides practitioners with a large toolkit of algorithms, kernels and solutions ready to use for standard pattern discovery problems in fields such as bioinformatics, text analysis, image analysis. Secondly it provides an easy introduction for students and researchers to the growing field of kernel-based pattern analysis, demonstrating with examples how to handcraft an algorithm or a kernel for a new specific application, and covering all the necessary conceptual and mathematical tools to do so. Contents: Preface; Part I Basic Concepts: 1. Pattern analysis; 2. Kernel methods: an overview; 3. Properties of Kernels; 4. Detecting stable patterns; Part II Pattern Analysis Algorithms: 5. Elementary algorithms in feature space; 6. Pattern analysis using eigendecompositions; 7. Pattern analysis using convex optimisation; 8. Ranking, clustering and data visualisation; Part III Constructing Kernels: 9. Basic kernels and kernel types; 10. Kernels for text.; 11. Kernels for structured data: strings, trees, etc.; 12. Kernels from generative models; Part IV Appendices; Appendix A Proof omitted from the main text; Appendix B Notational conventions; Appendix C List of pattern analysis methods; Appendix D List of kernels; Bibliography; Index. ISBN: 9780521813976 476pp £ 55.00 BIOTECHNOLOGY/ BIOINFORMATICS Digital Image Processing for Medical Applications Geoff Dougherty California State University, Channel Islands NEW Image processing is a hands-on discipline, and the best way to learn is by doing. This text takes its motivation from medical applications and uses real medical images and situations to illustrate and clarify concepts and to build intuition, insight and understanding. Designed for advanced undergraduates and graduate students who will become end-users of digital image processing, it covers the basics of the major clinical imaging modalities, explaining how the images are produced and acquired. It then presents the standard image processing operations, focusing on practical issues and problem solving. Crucially, the book explains when and why particular operations are done, and practical computerbased activities show how these operations affect real images. All images, links to the public-domain software ImageJ and custom plug-ins, and selected solutions are available from www.cambridge.org/books/dougherty. Contents: Preface; 1. Introduction; 2. Imaging systems; 3. Medical images obtained with ionizing radiation; 4. Medical images obtained with nonionizing radiation; 5. Fundamentals of digital image processing; 6. Image enhancement in the spatial domain; 7. Image enhancement in the frequency domain; 8. Image restoration; 9. Morphological image processing; 10. Image segmentation; 11. Feature recognition and classification; 12. Three-dimensional visualization; 13. Medical applications of imaging; 14. Frontiers of image processing in medicine; Appendix A. The Fourier Series and Fourier Transform; Appendix B. Set theory and probability; Appendix C. Shape and texture; Bibliography; Index. ISBN: 9780521181938 462pp ` 695.00 58
Biomechanics Concepts and Computation Cees Oomens Technische Universiteit Eindhoven, Holland Marcel Brekelmans Technische Universiteit Eindhoven, Holland & Frank Baaijens Technische Universiteit Eindhoven, Holland NEW This quantitative approach integrates the classical concepts of mechanics and computational modelling techniques, in a logical progression through a wide range of fundamental biomechanics principles. Online MATLAB ® -based software, along with examples and problems using biomedical applications, will motivate undergraduate biomedical engineering students to practise and test their skills. The book covers topics such as kinematics, equilibrium, stresses and strains, and also focuses on large deformations and rotations and non-linear constitutive equations, including visco-elastic behaviour and the behaviour of long slender fibrelike structures. This is the first textbook that integrates both general and specific topics, theoretical background and biomedical engineering applications, as well as analytical and numerical approaches. This is the definitive textbook for students. Contents: Preface; 1. Vector calculus; 2. The concepts of force and moment; 3. Static equilibrium; 4. The mechanical behaviour of fibres; 5. Fibres: time dependent behaviour; 6. Analysis of a one-dimensional continuous medium; 7. Biological materials and continuum mechanics; 8. Stress in three-dimensional continuous media; 9. Motion: the time as an extra dimension; 10. Deformation and rotation, deformation rate and spin; 11. Local balance of mass, momentum and energy; 12. Constitutive modelling of solids and fluids; 13. Solution strategies for solid and fluid mechanics problems; 14. Numerical solution of one-dimensional diffusion equation; 15. The onedimensional convection-diffusion equation; 16. The three-dimensional convection-diffusion equation; 17. Shape functions and numerical integration; 18. Infinitesimal strain elasticity problems; References; Index. Microbial Biotechnology Fundamentals of Applied Microbiology 2nd Edition Alexander N. Glazer University of California, Berkeley & Hiroshi Nikaido University of California, Berkeley Knowledge in microbiology is growing exponentially through the determination of genomic sequences of hundreds of microorganisms and the invention of new technologies such as genomics, transcriptomics, and proteomics, to deal with this avalanche of information. These genomic data are now exploited in thousands of applications, ranging from those in medicine, agriculture, organic chemistry, public health, biomass conversion, to biomining. Microbial Biotechnology: Fundamentals of Applied Microbiology focuses on uses of major societal importance, enabling an indepth analysis of these critically important applications. Some, such as wastewater treatment, have changed only modestly over time, others, such as directed molecular evolution, or ‘green’ chemistry, are as current as today’s headlines. This fully revised second edition provides an exciting interdisciplinary journey through the rapidly changing landscape of discovery in microbial biotechnology. An ideal text for courses in applied microbiology and biotechnology courses, this book will also serve as an invaluable overview of recent advances in this field for professional life scientists and for the diverse community of other professionals with interests in biotechnology. Contents: Preamble; 1. Microbial diversity; 2. Microbial biotechnology, scope, techniques and examples; 3. Production of proteins in bacteria and yeast; 4. The world of ‘omics’ - genomics, transcriptomics, proteomics and metabolomics; 5. Recombinant and synthetic vaccines; 6. Plantmicrobe interactions; 7. Microbial insecticides; 8. Microbial polysaccharides and polyesters; 9. Amino acids; 10. Antibiotics; 11. Biocatalysis in organic chemistry; 12. Biomass; 13. Ethanol; 14. Environmental applications. ISBN: 9780521875585 346pp ` 2400.00 ISBN: 9780521729673 576pp ` 595.00 Introductory Biomechanics C. Ross Ethier University of Toronto & Craig A. Simmons University of Toronto Introductory Biomechanics is a new, integrated text written specifically for engineering students. It provides a broad overview of this important branch of the rapidly growing field of bioengineering. A wide selection of topics is presented, ranging from the mechanics of single cells to the dynamics of human movement. No prior biological knowledge is assumed and in each chapter, the relevant anatomy and physiology are first described. The biological system is then analyzed from a mechanical viewpoint by reducing it to its essential elements, using the laws of mechanics and then tying mechanical insights back to biological function. This integrated approach provides students with a deeper understanding of both the mechanics and the biology than from qualitative study alone. The text is supported by a wealth of illustrations, tables and examples, a large selection of suitable problems and hundreds of current references, making it an essential textbook for any biomechanics course. 59
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