Our Role in Establishment of Rasa-Aushadhi ... - Techno Ayurveda

Excellence of Rasaaushadhi In Ayurveda Practice – Part 2 

Instead of cursing the darkness 

Try to lit a small LIGHT – 

It becomes FLAME 

one day to cook your food 

Our Role in Establishment 

of 

Rasa-Aushadhi Glory in 

General Ayurveda Practice 

Dr. K. Shiva Rama Prasad, at http://technoayurveda.wordpress.com/ 

1

స “రస” ైదుయ్లకు అనందనలో 

A 

Technoayurveda International 

Presentation 

In 

Association with 

Ayurmitra 

Technoayurveda.wordpress.com 

Rasashastra Re-Orientation Program at 

NRS Govt. Ayurveda College, Vijayawada 

on 15-12-2009 

2

Excellence of Rasaaushadhi In Ayurveda Practice 

Rasa Aushadhi Common Diseases in GAP Research in RT 

Dhatuvada - Dehavedha 

न च रसशास्तर्ं धातुवादाथर्मेवेित मन्तव्यं 

देहवेधद्वार मुक्ते रेव परमूयोजनत्वात् 

रसेश्वर दशर्न 

‣ Conversion of the lower metals to higher is 

the job of “Chemistry”. 

‣ What is expected from “Rasashastra” is to 

make is the “Dehavedha” for the body to 

attain the “Mukti” from “Disease” 


3



Introduction 

• Rasashastra a Scientific Chemotherapy 

of Ayurveda is at Cross-Roads 

• The influences and advancements of - 

– “Pharmacy standards” 

– “Evidence Based Medicine protocols” 

– A major Global “Toxic concept campaign” and 

– “Ayurveda Fraternity Deception” 

• - are making panic to the Ayurveda 

community in general and Rasashastra 

(Pharmacy) division in specific. 


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Ayurveda in Research 

• The Excellency to bring back – Research in 

the any branch especially in Rasashastra is 

essential. 

• Ayurveda has many units of Research like – 

CCRAS, ICMR and many NGOs for making 

Research and informing the Research fruits 

to the user. 

– Whether the Researches in Ayurveda are 

User demand fulfillments 

– Are the Researches followed are up to 

the International standard to accept 

Globally our Medicine 

– Are we make user to satisfy by the – 

• “Standard” 

• “Effect” or 

• “Free of Toxicity” 

• By any other way . . . At least . . . 


5



Need of the Hour 

• To be frank the researches in Ayurveda 

are not user friendly and could not reach 

the ultimate user – General Ayurveda 

Practitioner 

• As we are at the Rasashastra researches 

in concern at present – it is necessary to 

know how the researches are made in this 

branch. 


6



Research in General 

• Researches are of many folds to obtain 

the “True Knowledge” – A search again 

and again to get the perfect knowledge. 

• Commonly followed are – 

– 1. Explorative Research 

• Literary 

• Experience survey 

– 2. Conclusive 

• Descriptive 

• Experimental 


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Research Process 

• Problem definition 

• Objectives set: purpose – place – status - means 

– Research questions 

– Hypothesis 

– Boundary of the study 

• Research design 

– Sampling – experiment – questioners 

• Data collection 

• Data analysis 

• Interpretation of results – should be with real world 

problem and conclusion 

• Validation of results 


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shadhi Common Diseases in GAP Research in RT Activity in Research 

Is Rasa-Medicine is Target oriented 

Rasa Parpati 

Parada 

Samanya 

Shodhana 

Gandhaka 

Samanya Shodhana 

Ghrita Bharjita 

Bhringaraja 

Godugdha 

Shodhita 

Gandhaka 

Lashuna + Saindhava 

with Lime Powder 

Hingulottha 

Parada 

Parpati 1 of 2 

Parpati 2 of 4 

hodhita Parada What Target differences are brought in usage of these 

combinations and permutations with set of combinations 

and permutations of Anupana, Sahapana in General 

Ayurveda Practice 


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Is Rasa-Medicine is Target oriented 

A cutting edge technology is the need of hour in Ayurveda. 

The road beyond Production & Practice should be visualized. 

Dravya Shodhana Probable 

Parada Hingulotha (Alimentary) Pittahara 

Lime powder 

(Ca+)(neural) Vatahara 

Lasuna + 

Saindhava 

(Tissue invader) 

Kaphahara 

Gandhaka Godugdha Agni 

Bhringaraj Panchabhutagni 

Whether the “Shodhana” makes the Dravya to reorganize the Chemical bonding 


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Parpati in Practice 

Parpati Additives Target 

Rasa 

Panchamruta 

Rasa + Gandhaka 

(Base combination) 

+ Loha, Abhraka 

Tamra 

Annavaha, Udakavaha 

Rasavaha, Lasika (Twak) 

Annavaha, Pranavaha 

Sukravaha 

Bola + Bola Rakta vaha, Artavavaha 

Loha + Loha Annavaha, Lasika (Twak) 

Swarna + Swarna Annavaha, Pranavaha 

Sukravaha 

Tamra 

Sweta 



+ Tamra, 

Vatsanabha 

Soraka, Sphatika, 

Navasara 

Annavaha, Mootravaha 

Lasika (Twak) 

Annavaha, Mootravaha 


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Raw drug collection - Identification 

Who Answers 

Pharmaceutical 

Ingredient 

Shodhana 

Single / Multiple 

Shodhita 

Ingredients 

Multiple Bhavana 

Multiple Preparation 

methods 

Marana 

Multi 

combinations 

Multiple Pharmacokinetics 

Multiple Pharmacodynamics 

Anupana 

Is there any Genotoxicity 

Drug Target Action 

Sahapana 

Aushadha Kaala 

Drug concentrations 

to maintain half life 

Drug Excretion 

Clinical 

attitudes 


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Another Example of Kupipakwa Rasayana 

• In Kupi pakwa Rasayana procedures – the medicine 

collection is from the “Talastha” or “Kantastha” and 

“Ubhayastha”. 

• Taking the example of “Somanatha tamra Bhasma and 

Malla Sindhura (Tamra sindhura) are from one preparation. 

– The “Kantastha” – called as Tamra Sidhura acts on STI, Tamaka 

Swasa 

– Where as – the “Talastha” collection called as Tamra Bhasma 

acts on – many diseases, especially on Annvaha, Pranavaha, 

Twak vikara, etc. 

• What makes the difference of collection in a process 

• Whether the target is to prepare one medicine in a 

pharmaceutical procedure or two Birds in one shot 

• Does such short cut methods are encouraged by the Learned 

community 


13


mmon Diseases in GAP Research in RT Activity in Research Research Methods to Adopt 

What Literary Research 

• Literary research in Rasashastra has a 

wide scope and is the need of the hour. 

• The print available Rasashastra books are 

few and the abundance of Manuscripts 

makes – a chance to explore Rasashastra. 

• For Eg. – a preparation have many 

dialects of preparation methods – 

scrutinizing them makes us to have a 

target oriented potent Medicine to reach. 


14


mmon Diseases in GAP Research in RT Activity in Research Research Methods to Adopt 

How to survey in RT 

• Survey and education of Rasa medicine 

usage in the practice is recorded – 

– What is the need for Practitioner 

• Symptom target 

• Disease target 

• Organ target 

• System target 

• Health target 

– What medicines are causing the adverse 

effects – Classified Recordings of - 

• Hypersensitivity 

• Hepato toxicity 

• Nephro toxicity 

• Neuro toxicity 


15


mon Diseases in GAP Research in RT Activity in Research Research Methods to Adopt 

Do we do Descriptive Research in RT 

• Much of the present day Researches are 

following the Descriptive Method researches 

– which are with limited scope - as – 

• Prospective study – common 

– Physico / Pharmaco -chemical studies 

– Drug effect in clinical study 

• Retrospective study – Reverse 

pharmacology study - uncommon in 

Ayurveda 


16


Research in RT Activity in Research Research Methods to Adopt Research Models 

Experimental Research in RT 

Experimental studies have no pickup in 

Ayurveda because of non-efficiencies 

/exposure in maintenance of – 

Animal Houses and 

Analytical lab. 

The limping or dependent studies are 

successful some times but not yielding 

the full-fledged fruits and results to the 

Ayurveda community. 

More systematic animal experiments 

and lab studies are required as the 

AYUSH is funding and encouraging for 

the “Expressive Projects” 


17


Activity in Research Research Methods to Adopt Research Models 

Research Models in RT 

• Best Research model for successful 

Penetration Rating in to market is through 

fulfilling the peoples needs – 

• Mathematical – 

– Inventory 

– Parametric 

– Replacement 

• Algorithmic – is a well-defined sequence steps 

to solve a problem 

– Combinational 

– Polynomial 


18



Inventory Research 

• Present day researches seems to validate ancient 

formulations rather than productivity 

• No contribution of the “Neo-Rasashastra” is 

brought forward 

• An inventory model is – 

– Classify and visualize the old formula as TLC, HPTC, 

Finger print technology, etc 

– Chemical structure is identified 

– Reconstruct the chains for validation and comparison 

– Restructure the combination to the needs of user 

– Rejuvenation of Vedic Chemistry 

– There by combating the present day dreadful diseases 


19



Parametric Research 

• A classical design of Research (validation)– 

mere Chemical constituents – studied with - 

– Pre-fixed Parameters 

– Chemical structure evaluated 

– Limited framework to study 

• A locality 

• One medicine 

• Small duration 

– Mono-directional 

– Target based 

– Result oriented 


20



Replacement Research 

• In Ayurveda – we are commonly using the 

substitutes – 

– Whether the replacements are equivalent 

– Does they give exactly results as their substitutes 

– we don’t know! 

• Instead – using Replacement Research is 

better – here we replace with – 

– Standard replacement 

– Equivalent replacement (based on Rasa, Guna, etc) 

– Omitting replacement 

– Complete replacement 


21


Research Methods to Adopt Research Models GAP in Research Conclusion 

Combinational Research 

• The medicines commonly used are of Herbomineral 

combinations 

• The combinational research in Rasashastra is 

defined as – 

– A team of Rasashastra - Chemistry – 

Botany – Pharmacy – Ayurveda Specialized 

Branch - are together to work on a 

compound – unbiased 

– Various methods of said preparations are 

compared for the – structure – safety 

(Toxicity) – economy - efficacy – 


22



Polynomial Research 

• It is defined as - A mathematical function that is 

the sum of a number of terms – 

– As the standards of the Ayurveda are unique and not 

fit to the “Rest of the World” – 

• A multi center – large sample – uni-directional studies are 

invited 

– This is possible by the universities or CCRAS or ICMR – 

creating a Nodal officer to control the studies all over – even the 

PG Centers 

• A common minimum policy is created to ensure 

the 

– Drug Safety 

– Half life 

– Target area and 

– Excretion 


23



Reverse Pathology – Reverse Pharmacology 

• Reverse pathology in Ayurveda is said as – Samprapti 

Vighatana 

• Planning of the Vighatana with the combination is the 

most important task in Ayurveda Practice. It is possible 

with the understanding of Ayurveda principles and 

application of – 

– Rasa 

– Guna 

– Veerya 

– Vipaka 

– Prabhava 

• Reverse Pharmacology is understood under the present 

day technology about – 

– Drug Excretion 

– Drug target 

– Half life, etc 


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Example • Madhumeha patho-physiology is – 

• Bahumootrantaka Ras – Tissues of body are liquidated - 

used in Madhumeha has – – The sugar reserves undertakes neo- 

• Ahiphena 

glucogenesis 

• Dadima 

– Non utilization of CHO by muscles or 

• Kadali 

even for transformation in to deposits 

• Parad 

– Free CHO (Shareera Kleda) mix with 

• Loha 

fluids (Ap Dhatu) of the body 

• Mouktika 

especially Rakta 

• Praval 

– Expresses as “Bahudrava shleshma 

• Shalmali 

yukta – Madhurakta” 

• Udumbara 

– The liquids mixed with CHO of the 

• Vanga 

body are transported to the KUB – 

termed as - Madhumeha 

– i.e. Elimination of excess fluids along 

with Shareera Kleda (Glucose) 

– The reverse pathology planned on 

these grounds are – in RED – & 

– Fluid Regulation 

– CHO Regulation 


25



Repatriation Hypothesis i.e. Reverse Pathology 

Ahiphena paralyzes 

sigmoid smooth 

mussels & Dadima 

prevents the fluid 

re absorption from 

colon by reverse 

peristalsis, Loha 

require maximum 

fluid for synthesis 

and absorbs the 

water once again – 

so, the fluid reentry 

in to system 

is regulated at the 

same time Shalmali 

absorbs the fluid in 

the colon 

Same time the Urine reabsorption 

from Henley's loop 

is retarded by Vanga, and 

Kadali 

- Udumbara makes the 

integumentary system 

(Lasika) to constrain and fluid 

retained is drained back to 

system 

1 

2 

Fluid Regulation 


26



Repatriation Hypothesis i.e. Reverse Pathology 

CHO Regulation 

Formation of shareera 

kleda – CHO is 

through Liver (Mamsa 

Khanda) and 

Pancreas – there by 

the Parada acts as 

agent to and prevents 

the neo-glycolysis 

3 

CHO combustion is done 

through rapid muscle 

movements by initiating 

Acetylcholine at motor 

endplates in muscle fiber 

through - Mouktika – 

Pravala 

Heat generated with 

muscle movement makes 

the bahudrava shleshma 

to evaporate 

5 

Shalmali, Parada 

initiates the 

pancreas to regulate 

the CHO 


4 

27


Activity in Research Research Methods to Adopt Research Models GAP in Research 

GAP Research Models 

• General Ayurveda Practitioners Research 

models are with – 

– Involved Data base recording and 

– submission to the nearest center for analysis – 

as a part of big survey 

• Suggesting the center for – 

– epidemic and endemic events and 

– actively participating in Health campaigns with 

– Evidence based Research drugs provided by 

the center in time 


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Activity in Research Research Methods to Adopt Research Models GAP in Research 

• Area specific diseases are submitted and a common drug 

therapy modules are adopted as per the centers advise 

• Center responsibilities - 

GAP Research Models 

– Periodical CME for the practitioners with in 50 -100 KM 

diameter 

– Door to door survey of health / disease conditions 

– Providing Easy access to the people about pro and 

cant's of drug 

– Life line access through telephone / Internet in 

Institutional / Hospital centers 

– Radio talks / TV shows / FM Radio services organized 

to create Awareness to the Local people 


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Responsibilities of Practitioner 

• Reclassify the usage of Rasaaushadhi in 

– Infectious 

– Metabolic 

– Emergencies, etc 

• Diseases of attention 

– AIDS 

– Cancer 

– ED 

– Paralysis 

• Developing the databank for EB Ay Medicine 

• Defining the Rasaushadhi in Departmental use – 

Shalya, Prasuthi, etc. 

• Suggestion of Contribution required in practice 

• Ethical practices in Rasa practice 


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• The Interference of too many or 

• No involvement 

Conclusion 

– is the problem in Ayurveda Research 

• Developing Teamwork instead & Working 

Unbiased in the Research and incorporating 

Rasaaushadhi vividly in General Ayurveda Practice 

are the solutions for development - because …. 

–आरोग्यम ् (रस) भाःकरािदच्छेत ् 


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Excellence of Rasaaushadhi In Ayurveda Practice – Part 2 

technoayurveda@gmail.com 

THANK YOU 

Dr. K. Shiva Rama Prasad 

Of . . . technoayurveda.wordpress.com It’s 

Technoayurveda on International 

Excellence of Rasaaushadhi In Ayurveda Presentation Practice 

Dr. K. Shiva Rama Prasad, Professor & Head, Kayachikitsa, Amrita School of Ayurveda, Kerala 

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Our Role in Establishment of Rasa-Aushadhi ... - Techno Ayurveda

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