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Dr. Mon-Juan Lee

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◎ <br />

2008.8~ Assistant Professor, Department of BioScience Technology,<br />

Chang Jung Christian University<br />

2007~2008 Postdoctoral Fellow, Institute of Biomedical Engineering,<br />

National Cheng Kung University, and Orthopaedic Research<br />

Center, Kaohsiung Medical University<br />

2006~2007 Postdoctoral Fellow, Institute of Medicine, Kaohsiung Medical<br />

University<br />

2003.7-10 Internship, <strong>Dr</strong>. R. Dickson’s Lab, Lombardi Cancer Center,<br />

Georgetown University, Washington DC, USA<br />

2000~2001 Assistant Researcher, R&D Department, ScinoPharm Taiwan,<br />

Ltd.<br />

◎ <br />

Ph.D. 2001~2006 Department of Life Science, National Tsing Hua<br />

University<br />

M.S. 1998~2000 Institute of Chemical Engineering, National Tsing<br />

Hua University<br />

B.S. 1994~1998 Department of Chemical Engineering, National<br />

Tsing Hua University<br />

◎ <br />

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Journals<br />

<strong>Lee</strong>, M. J.*, J. R. Hsu, Y. J. Wang, and C. Y. Chen. Polyamines are potent<br />

osteogenic inducers of human bone marrow-derived mesenchymal stem<br />

cells (In preparation). (*Corresponding author)<br />

<strong>Lee</strong>, M. J., H. T. Chen, C. M. Huang, G. J. Wang, M. L. Ho, and J. K.<br />

Chang. Suppression of PPARγ induces osteogenic gene expression and<br />

differentiation of adipose tissue-derived stem cells (Submitted).<br />

Chen, H. T. # , M. J. <strong>Lee</strong> # , M. L. Ho, C. H. Chen, S. H. Hung, H. I. Wang, Y.<br />

C. Fu, Y. H. Wang, G. J. Wang, and J. K. Chang. Osteogenic potential of<br />

human adipose tissue-derived stem cells in the elderly. J. Cell Mol. Med.<br />

(Revised). ( # The authors contributed equally to this work.)<br />

<strong>Lee</strong>, M. J., Liu, C. L., and H. Huang. 2010. Identification and biochemical<br />

characterization of a unique Mn 2+ -dependent UMP kinase from<br />

Helicobacter pylori. Arch. Microbiol.192: 739-746.<br />

Huang, Y. P., M. J. <strong>Lee</strong>, M. K. Yang, and C. W. Chen. 2010. The effects of<br />

montmorillonite-clay alignment on the crystallization and ion-conducting<br />

behaviors of poly(ethylene oxide)-nanocomposites. Appl. Clay Sci. 49:<br />

163-169.<br />

Ho, M. L., Y. H. Chen, H. J. Liao, C. H. Chen, S. H. Hung, M. J. <strong>Lee</strong>, G. J.<br />

Wang, J. K. Chang. 2009. Simvastatin increases osteoblasts and<br />

osteogenic proteins in ovariectomized rats. Eur. J. Clin. Invest. 39:<br />

296-303.<br />

<strong>Lee</strong>, M. J., H. Huang, W. Lin, R. R. Yang, C. L. Liu, and C. Y. Huang.<br />

2007. Activation of Helicobacter pylori inorganic pyrophosphatase and the<br />

importance of Cys16 in thermostability, enzyme activation and quaternary<br />

structure. Arch. Microbiol. 188: 473-482.<br />

<strong>Lee</strong>, M. J., C. H. Liu, S. Y. Wang, C. T. Huang, and H. Huang. 2006.<br />

Characterization of the Soj/Spo0J chromosome segregation proteins and<br />

identification of putative parS sequences in Helicobacter pylori. Biochem.<br />

Biophys. Res. Commun. 342: 744-50.<br />

<strong>Lee</strong>, M. J., C. Y. Huang, Y. J. Sun, and H. Huang. 2005. Cloning and<br />

characterization of spermidine synthase and its implication in polyamine<br />

biosynthesis in Helicobacter pylori strain 26695. Protein Expr. Purif. 43:<br />

140-8.<br />

Lu, P. K., S. Y. Chien, J. Y. Tsai, C. T. Fong, M. J. <strong>Lee</strong>, H. Huang, and Y.<br />

J. Sun. 2004. Crystallization and preliminary X-ray diffraction analysis of<br />

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spermidine synthase from Helicobacter pylori. Acta Crystallogr. D Biol.<br />

Crystallogr. 60: 2067-9.<br />

Hung, R. J., I. W. J. Hsu, J. L. <strong>Dr</strong>eiling, M. J. <strong>Lee</strong>, C. A. Williams, M. D.<br />

Oberst, R. B. Dickson, and C. Y. Lin. 2004. Assembly of adherens<br />

junctions is required for sphingosine 1-phosphate-induced matriptase<br />

accumulation and activation at mammary epithelial cell-cell contacts. Am.<br />

J. Physiol. Cell Physiol. 286: C1159-69.<br />

Conference Papers<br />

International Conference<br />

<strong>Lee</strong>, M. J., Y. P. Huang, M. K. Yang, C. W. Chen, and C. H. Lin.<br />

Crystallization and ion-conducting behaviors of poly(ethylene<br />

oxide)-nanocomposite under an electric field. 238th ACS National Meeting<br />

& Exposition, Washington DC, USA, August 16-20, 2009.<br />

Wang, Y. H., M. J. <strong>Lee</strong>, J. K. Chang, M. L. Ho, H. C. Chu, S. C. Lai, and G.<br />

J. Wang. Transfection of Human Bone Marrow Stromal Cells Using<br />

Microporation, an Effective Non-Viral Transfection Technique. 55th Annual<br />

Meeting of the Orthopaedic Research Society, Las Vegas, Nevada, USA,<br />

February 22-25, 2009.<br />

<strong>Lee</strong>, M. J., C. M. Huang, H. T. Chen, G. J. Wang, M. L. Ho, and J. K.<br />

Chang. Suppression of PPARγ Induces Osteogenic Gene Expression and<br />

Differentiation of Adipose Tissue-Derived Stem Cells. 55th Annual Meeting<br />

of the Orthopaedic Research Society, Las Vegas, Nevada, USA, February<br />

22-25, 2009.<br />

Hui-Ting Chen, Mei-Ling Ho, <strong>Mon</strong>-<strong>Juan</strong> <strong>Lee</strong>, Chung-Hwan Chen, Hsin-I<br />

Wang, Yi-Hui Chen, Gwo-Jaw Wang, Je-Ken Chang. Osteogenic potential<br />

of human adipose tissue-derived stem cells in the elderly osteoporotic<br />

population. Sixth ISSCR Annual Meeting, Philadelphia, USA, June 11-14,<br />

2008.<br />

<strong>Lee</strong>, M. J., H. Huang, C. K. Chou, Y. C. Tsai, F. G. Tseng, and C. C.<br />

Chieng. Diagnostic antigens and antibodies patterned by micro stamping<br />

system. Sixth International Conference on Miniaturized Chemical and<br />

Biochemical Analysis Systems, Nara New Public Hall, Nara, Japan,<br />

November 3-7, 2002.<br />

Local Conference<br />

<strong>Lee</strong>, M. J. Effect of polyamines on the osteogenic differentiation of human<br />

bone marrow-derived mesenchymal stem cells. Sixth Annual Meeting of<br />

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Taiwan Society for Stem Cell Research (TSSCR), Taichung, Taiwan,<br />

October 9, 2010. (Plenary speaker)<br />

<strong>Lee</strong>, M. J., C. M. Huang, H. T. Chen, G. J. Wang, M. L. Ho, and J. K.<br />

Chang. Suppression of PPARγ Induces Osteogenic Gene Expression and<br />

Differentiation of Adipose Tissue-Derived Stem Cells. Annual meeting of<br />

Orthopaedic Association ROC, Taoyuan, Taiwan, October 25-26, 2008.<br />

<strong>Lee</strong>, M. J., H. T. Chen, M. L. Ho, Y. H. Chen, H. I. Wang, G. J. Wang, and<br />

J. K. Chang. Osteogenic Potentials of Adipose Tissue-Derived Stem Cells:<br />

An in vivo Study. Annual meeting of Orthopaedic Association ROC,<br />

Taoyuan, Taiwan, October 25-26, 2008.<br />

Chang, J. K., H. T. Chen, C. M. Huang, M. J. <strong>Lee</strong>, G. J. Wang, and M. L.<br />

Ho. Enhancement of osteogenesis through interfering PPARγ2 mRNA in<br />

3T3-L1 cell line. Annual meeting of Orthopaedic Association ROC,<br />

Taoyuan, Taiwan, October 27-28, 2007.<br />

<strong>Lee</strong>, M. J., W. Lin, R. Lo, R. R. Yang and H. Huang. Characterization of<br />

wild-type and mutant spermidine synthases from Escherichia coli. The 21 st<br />

Joint Annual Conference of Biomedical Sciences, pp. 231, 2006.<br />

<strong>Lee</strong>, M. J., C. Y. Huang, I. Z. Sam and H. Huang. Molecular cloning and<br />

functional characterization of HP0832 gene from Helicobacter pylori. The<br />

Nineteenth Joint Annual Conference of Biomedical Sciences, pp. 327,<br />

2004.<br />

<strong>Lee</strong>, M. J. and I. M. Chu. Study on the air/water interfacial adsorption of an<br />

egg phosphatidylcholine and Tween 80 mixture. The Fifth Conference on<br />

Biomedical Engineering, pp. 595, 2000.<br />

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